Clinical Trials on BRAF Mutation-Related Tumors
Total 2245 results
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AIO-Studien-gGmbHUniversitätsklinikum Hamburg-Eppendorf; Merck Serono GmbH, Germany; Pierre Fabre...RecruitingColorectal Cancer | Colon Cancer | BRAF V600 Mutation | BRAF V600E | Localized CancerGermany
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National Cancer Institute (NCI)Active, not recruitingMetastatic Melanoma | Stage III Cutaneous Melanoma AJCC v7 | Stage IV Cutaneous Melanoma AJCC v6 and v7 | Metastatic Malignant Solid Neoplasm | Stage IIIC Cutaneous Melanoma AJCC v7 | Unresectable Solid Neoplasm | BRAF V600E Mutation Present | BRAF V600K Mutation Present | Stage IIIA Cutaneous Melanoma... and other conditionsUnited States
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Boehringer IngelheimCompletedSolid Tumors, KRAS MutationJapan
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University of California, San FranciscoGlaxoSmithKlineRecruitingMetastatic Solid Tumor | BRCA1 Mutation | BRCA2 Mutation | PALB2 Gene Mutation | ATM Gene MutationUnited States
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Guangdong Provincial People's HospitalShanghai Junshi Bioscience Co., Ltd.RecruitingNon-Small Cell Lung Cancer | BRAF V600 Mutation | MET Amplification | MET Exon 14 Skipping Mutation | RET Driver Mutation | Erb-B2 Receptor Tyrosine Kinase Exon 20 MutationChina
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Pierre Fabre MedicamentCompletedMelanoma | BRAF V600E Unresectable or Metastatic Melanoma | BRAF V600E Metastatic NSCLCChina
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Boehringer IngelheimActive, not recruitingSolid Tumors, KRAS MutationSpain, United Kingdom, United States, Belgium
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Sidney Kimmel Comprehensive Cancer Center at Johns...Bristol-Myers Squibb; Vanderbilt University; Avon Breast Health Access FundActive, not recruitingMetastatic Solid Tumor | SF3B1 Gene Mutation | Spliceosome Mutation | U2AF1 Gene Mutation | SRSF2 Gene MutationUnited States
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Sun Yat-sen UniversityNot yet recruitingNSCLC | BRAF V600 Mutation | MET Exon 14 MutationChina
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M.D. Anderson Cancer CenterNational Cancer Institute (NCI)CompletedMetastatic Malignant Neoplasm | Advanced Malignant Neoplasm | Recurrent Malignant Neoplasm | Refractory Malignant Neoplasm | BRAF Gene MutationUnited States
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City of Hope Medical CenterNational Cancer Institute (NCI)RecruitingThyroid Gland Anaplastic Carcinoma | BRAF V600K Mutation Present | BRAF NP_004324.2:p.V600EUnited States
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Boehringer IngelheimActive, not recruitingSolid Tumors, KRAS Mutation; SOS1United States, Netherlands, Germany
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Ambrx, Inc.WithdrawnHER2 Mutation-Related Tumors | HER2 Amplified Solid TumorsUnited States
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Gustave Roussy, Cancer Campus, Grand ParisActive, not recruitingMetastatic Radioactive Iodine Refractory Thyroid Cancer Patients With RAS or BRAF MutationFrance
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Faeth TherapeuticsActive, not recruitingAdvanced Solid Tumor | PIK3CA Mutation | PTEN Loss of Function MutationUnited States
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Dr Cipto Mangunkusumo General HospitalCompletedColorectal Cancer | APC Gene Mutation | TP53 Gene Mutation | PIK3CA Gene Mutation | KRAS Mutation-Related Tumors | MLH1 Gene MutationIndonesia
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Pamela MunsterNovartisWithdrawnLocally Advanced Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm | Solid Tumors, Adult | HPV-Related Squamous Cell Carcinoma | Human Papillomavirus-Related Carcinoma | PIK3CA Mutation-Related Tumors | PIK3CA Mutation | Human Papillomavirus-Related Squamous Cell CarcinomaUnited States
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Hubei Biological Medicine Industrial Technology...UnknownAdvanced Solid Tumors | HRD | BRCA MutationChina
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Poitiers University HospitalCompletedPancreatic Cancer | Circulating Tumor DNA | KRAS Mutation-Related Tumors
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Sidney Kimmel Comprehensive Cancer Center at Johns...Merck Sharp & Dohme LLCActive, not recruitingHigh Tumor Mutation Burden | High TMB (Tumor Mutation Burden) | MSS (Microsatellite Stable)United States
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Children's Oncology GroupNational Cancer Institute (NCI)RecruitingCentral Nervous System Tumor | Somatic Mutation | Pediatric Central Nervous System Tumor | Discordant TwinUnited States
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Calithera Biosciences, IncCompletedNSCLC | Solid Tumors | KRAS Gene Mutation | CRCUnited States
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The First Affiliated Hospital of Soochow UniversityRecruitingCore Binding Factor Acute Myeloid Leukemia | KIT Mutation-Related TumorsChina
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Korean Cancer Study GroupUnknownMetastatic Solid Tumor | DDR Gene MutationKorea, Republic of
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University Health Network, TorontoBayer; AstraZeneca; Amgen; Applied Health Research Centre; Takeda Canada, Inc.; Programs...RecruitingCancer | Malignancies Multiple | Malignant Solid Tumor | Cancer, Therapy-Related | Molecular Sequence Variation | Genetic Alteration | Gene Fusion | Receptor Tyrosine Kinase Gene Mutation | RTK Family Gene Mutation | Ras (Kras or Nras) Gene MutationCanada
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Federation Francophone de Cancerologie DigestiveMerck Sharp & Dohme LLC; Pierre Fabre LaboratoriesRecruitingColorectal Cancer | BRAF V600E Mutation PositiveFrance
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Boehringer IngelheimCompleted
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Technische Universität DresdenTerminatedBrain Metastases | Malignant Melanoma Stage IV | BRAF V600 MutationGermany
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UNICANCERPierre Fabre MedicamentRecruitingMetastatic Colorectal Cancer | BRAF V600E Mutation PositiveFrance
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Prisma Health-UpstateIpsenRecruitingSolid Tumor | ARID1A Gene MutationUnited States
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Boehringer IngelheimRecruitingSolid Tumor, KRAS MutationUnited States, Taiwan, Japan
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University of California, San FranciscoNovartisCompletedBRAF Mutant Metastatic MelanomaUnited States
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Cascadian Therapeutics Inc.TerminatedAdvanced BRAF-mutant CancersUnited States
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Pierre Fabre MedicamentClinactCompletedMetastatic Colorectal Cancer | BRAF V600E Mutation PositiveFrance, United Kingdom, Spain, Belgium, Germany, Italy, Austria
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Novartis PharmaceuticalsCompletedBRAF-positive Metastatic MelanomaUnited States
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Thai Red Cross AIDS Research CentreChulalongkorn University; Queen Savang Vadhana Memorial Hospital, ThailandCompletedNVP Plasma Level | NVP Related Mutation | 3TC Related MutationThailand
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UNICANCERMerck Sharp & Dohme LLC; Pierre Fabre Medicament; European Association of Dermato...RecruitingBrain Metastases | Malignant Melanoma | BRAF V600 MutationFrance
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Frontier Medicines CorporationRecruitingColorectal Cancer | Pancreatic Cancer | Non Small Cell Lung Cancer | Metastatic Solid Tumor | Solid Tumor, Adult | Unresectable Solid Tumor | KRAS G12C | Advanced Solid Tumors With KRAS G12C MutationsUnited States
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Idience Co., Ltd.Active, not recruitingSolid Tumors | Homologous Recombination Deficiency | Homologous Recombination Repair Gene MutationKorea, Republic of
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Abramson Cancer Center of the University of PennsylvaniaCompletedAdvanced BRAF Mutant MelanomaUnited States
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Sun Yat-sen UniversityRecruitingNon-small Cell Lung Cancer (NSCLC) | EGFR-TKI Resistant Mutation | EGFR-TKI Sensitizing Mutation | Somatic Mutation | Germline MutationsChina
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PfizerCompletedBRAF or NRAS Mutant Metastatic MelanomaUnited States, Netherlands, Italy, Germany, Switzerland
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Novartis PharmaceuticalsCompletedBRAF v600 Mutated Metastatic MelanomaUnited States
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AmgenActive, not recruitingAdvanced/Metastatic Solid Tumors With KRAS p.G12C MutationTaiwan, Hong Kong
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D3 Bio (Wuxi) Co., LtdRecruitingAdvanced Solid Tumors With MAPK Pathway MutationsAustralia, China, United States
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University Medical Center NijmegenRecruitingOvarian Cancer | BRCA1 Gene Mutation | BRCA2 Gene Mutation | RAD51C Gene Mutation | RAD51D Gene Mutation | BRIP1 Gene MutationNetherlands, United States, Belgium, Norway, Poland, Italy, Australia, Mexico, Brazil, Sweden, Uruguay
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Array BioPharmaTerminatedLocally Advanced Metastatic BRAF Mutant MelanomaAustralia, Canada, Netherlands, United States
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Novartis PharmaceuticalsCompletedBRAF Positive Metastatic MelanomaUnited States
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Northwestern UniversityNational Cancer Institute (NCI)RecruitingColorectal Cancer | Colorectal Cancer Stage IV | Stage IV Colorectal Cancer Positive for BRAF V600E MutationUnited States
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Xynomic Pharmaceuticals, Inc.Not yet recruitingMelanoma | Cancer | Colorectal Cancer | Nonsmall Cell Lung Cancer | Thyroid Cancer | BRAF V600 Mutation