Clinical Trials on BRCA Gene Rearrangement
Total 861 results
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Peking University Cancer Hospital & InstituteNot yet recruitingColorectal Cancer | Radiofrequency Ablation | Liver Metastasis | KRAS Gene | Safe Margin
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Shanghai University of Traditional Chinese MedicineUnknownGene Mutation-Related Cancer | Traditional Chinese Medicine
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Universitat Pompeu FabraHospital Universitari Joan XXIII de Tarragona.Completed
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Orthofix s.r.l.CompletedJoint Diseases | Genu Varum | Genu Valgum | Knee Deformity | Ankle Deformity | Length Inequality, Leg | Discrepancy Length; Congenital | Deformity of LimbItaly
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Mayo ClinicNational Cancer Institute (NCI)RecruitingRecurrent B-Cell Non-Hodgkin Lymphoma | Recurrent Primary Mediastinal (Thymic) Large B-Cell Lymphoma | Recurrent High Grade B-Cell Lymphoma With MYC, BCL2, and BCL6 Rearrangements | Refractory High Grade B-Cell Lymphoma With MYC, BCL2, and BCL6 Rearrangements | Recurrent Diffuse Large B-Cell... and other conditionsUnited States
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AstraZenecaParexel; Covance; Iqvia Pty Ltd; Theradex; Myriad Genetics, Inc.CompletedNon-Germline BRCA Mutated Ovarian CancerItaly, Spain, Sweden, Canada, Czechia, Poland, United Kingdom, Israel, Austria, Belgium, Switzerland, Netherlands, Bulgaria, Finland, Norway, Denmark, Slovenia, Portugal
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AstraZenecaCompletedBRCA or HRR+ Mutated Ovarian Cancer PatientsItaly, Spain, Canada, Czechia, Poland, United Kingdom, Hungary, Bulgaria
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AstraZenecaNo longer availablePSR Ovarian Cancer With a BRCA MutationJapan
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Shanghai General Hospital, Shanghai Jiao Tong University...Not yet recruitingTo Evaluate the Scaling Clinical Study of AAV2-RPE65 Gene Therapy Agent (LX101) in Patients With Congenital Amaurosis (LCA)
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Hunan Province Tumor HospitalNot yet recruitingLung Adenocarcinoma | ALK Gene Mutation | ImmunotherapyChina
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XuanwuH 2University of CologneRecruitingAlzheimer Disease | Subjective Cognitive Decline | Neuroimaging | GeneChina
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Memorial Sloan Kettering Cancer CenterMerck Sharp & Dohme LLC; Genentech, Inc.RecruitingEsophageal Cancer | Gastric Adenocarcinoma | HER2 Gene MutationUnited States
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Regeneron PharmaceuticalsRecruitingCongenital Hearing Loss Secondary to Biallelic Mutations of the Otoferlin Gene (OTOF)Spain, United Kingdom, United States
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Fundamenta Therapeutics, Ltd.The First Affiliated Hospital of Zhengzhou UniversityNot yet recruitingAllogeneic, CAR-T, Protein Sequestration, Non-gene Edited
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Institute of Hematology & Blood Diseases HospitalRecruiting
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Shengjing HospitalNot yet recruitingPostoperative Delirium | General Anesthesia | Circadian Rhythm Disorders | Exosomes | Clock GeneChina
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University College, LondonNIHR Rare Diseases Translational Research Collaboration; Barts Cardiovascular...RecruitingLamin A/C Gene Mutation | Dilated Cardiomyopathy, FamilialUnited Kingdom
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The Hospital for Sick ChildrenThe National Pancreas FoundationWithdrawnCystic Fibrosis | CFTR Gene Dysfunction
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Changhoon YooCompletedCholangiocarcinoma | Biliary Tract Cancer | HER-2 Gene Amplification | HER-2 Protein OverexpressionKorea, Republic of
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Beijing Tongren HospitalUnknownNeuromyelitis Optica | Glucocorticoid Resistance | GeneChina
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Cancer Institute and Hospital, Chinese Academy...Not yet recruitingEarly-stage Triple-negative Breast Cancer With BRCA1/2 MutationsChina
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Northwestern UniversityNational Institutes of Health (NIH); National Institute on Deafness and Other...CompletedStroke | Aphasia | Anomia | Dysgraphia | AgrammatismUnited States
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Shirley Ryan AbilityLabU.S. Department of EducationCompleted
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David Bond, MDRecruitingRecurrent Primary Mediastinal (Thymic) Large B-Cell Lymphoma | Refractory Primary Mediastinal (Thymic) Large B-Cell Lymphoma | Recurrent High Grade B-Cell Lymphoma With MYC, BCL2, and BCL6 Rearrangements | Refractory High Grade B-Cell Lymphoma With MYC, BCL2, and BCL6 Rearrangements | Recurrent... and other conditionsUnited States
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University of Texas Southwestern Medical CenterCompletedAnatomic Stage I Breast Cancer AJCC v8 | Anatomic Stage IA Breast Cancer AJCC v8 | Anatomic Stage IB Breast Cancer AJCC v8 | Anatomic Stage II Breast Cancer AJCC v8 | Anatomic Stage IIA Breast Cancer AJCC v8 | Anatomic Stage IIB Breast Cancer AJCC v8 | Anatomic Stage IIIA Breast Cancer AJCC v8 | Prognostic... and other conditionsUnited States
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Fudan UniversityNot yet recruitingLung Cancer | Minimal Residual Disease | EGFR Gene Mutation
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Stanford UniversityNot yet recruitingPTEN Gene Mutation | PTEN Hamartoma Tumor Syndrome | PTEN Hamartoma SyndromeUnited States
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David E GerberCancer Prevention Research Institute of Texas; Sagimet Biosciences Inc.Recruiting
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OnKure, Inc.Active, not recruitingMelanoma | NRAS Gene Mutation | RAS MutationUnited States
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Kuopio University HospitalMedical University of Vienna; Rigshospitalet, Denmark; University College, London and other collaboratorsActive, not recruitingCoronary Artery Disease | Refractory Angina Pectoris | Gene TransferDenmark, Finland
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European Institute of OncologyActive, not recruitingLobular Breast Carcinoma | CDH1 Gene InactivationItaly
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Shanghai Pulmonary Hospital, Shanghai, ChinaCompletedEGFR Gene Mutation | Lung Adenocarcinoma Stage IIIChina
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Chul KimBristol-Myers Squibb; AstraZeneca; Walter Reed National Military Medical Center; Hackensack Meridian HealthActive, not recruitingNonsmall Cell Lung Cancer | EGFR Gene MutationUnited States
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Korean Association for the Study of Targeted TherapyChonnam National University Hospital; Kyungpook National University Hospital; Konkuk University Medical Center and other collaboratorsCompletedHER2 Gene Mutation | Adenocarcinoma Lung Stage IVKorea, Republic of
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Thammasat UniversityCompletedPrimary Gonarthrosis | Genu Recurvatum
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AstraZenecaCompletedRelapsed Ovarian Cancer, BRCA Mutation, Platinum SensitivityUnited States, Canada
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AGO Research GmbHCompleted
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Centre Hospitalier Universitaire de la RéunionNot yet recruitingBreast Cancer | BRCA2 Mutation | Genetic Disease
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Fondazione Policlinico Universitario Agostino Gemelli...RecruitingNSCLC Stage IV | ALK Gene Mutation | ALK Sensitizing MutationItaly
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The Fourth Affiliated Hospital of Zhejiang University...CompletedNSCLC | EGFR Gene Mutation | Non-small-lung-cell CancerChina
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Turning Point Therapeutics, Inc.Active, not recruitingAdvanced Solid Tumor | Metastatic Solid Tumors | MET Gene AlterationsUnited States, France, Korea, Democratic People's Republic of, Korea, Republic of, Spain
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Fondazione I.R.C.C.S. Istituto Neurologico Carlo...University of Campania "Luigi Vanvitelli"; IRCCS National Neurological Institute...Active, not recruitingParkinson Disease | GBA Gene MutationItaly
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Aarhus University HospitalRoche Pharma AGEnrolling by invitationLung Cancer | ALK Gene Mutation | Resistance, Disease | MutationDenmark
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Second Affiliated Hospital of Wenzhou Medical UniversityRecruitingInflammatory Bowel Disease | Gene Abnormality | ChineseChina
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Hunan Province Tumor HospitalRecruitingCarcinoma, Non-Small Cell Lung | EGFR Gene MutationChina
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Daping Hospital and the Research Institute of Surgery...CompletedNSCLC | Advanced Cancer | EGFR Gene Amplification | Stage IV NSCLC | Stage IIIB NSCLCChina
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Murdoch Childrens Research InstituteRoyal Children's Hospital; Peter MacCallum Cancer Centre, AustraliaNot yet recruitingArteriovenous Malformations | Vascular Malformations | MAP2K1 Gene Mutation | PIK3CA-related Overgrowth Spectrum | Vascular Anomalies | Lymphangioma | Lymphatic Malformation | KRAS G12D | Venous Malformation | Vascular Anomaly | KRAS G12C | PI3K Gene Mutation | Slow-Flow Vascular Malformation | Fast-Flow Vascular... and other conditionsAustralia
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Memorial Sloan Kettering Cancer CenterCompletedOvarian Cancer | Non Small Cell Lung Cancer | RET Gene Mutation | BRAF Gene MutationUnited States
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Children's Hospital Medical Center, CincinnatiRecruitingNeurofibromatosis 1 | Noonan Syndrome | Legius Syndrome | Cardiofaciocutaneous Syndrome | Costello Syndrome | SYNGAP1-Related Intellectual Disability | DLG4 | RAS Mutation | Noonan Syndrome With Multiple Lentigines | Noonan Neurofibromatosis Syndrome | Smith-Kingsmore Syndrome | MTOR Gene Mutation | GATOR-1 Gene... and other conditionsUnited States
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Tanta UniversityCompletedDeformity of Limb | Deformity Knee