Clinical Trials on BRCA 1 Gene Mutation

BRCA1 and BRCA2 Mutation Carrier and BRCAness Phenotype

Italy

Metastatic Breast Cancer | BRCA1 Mutation

Poland

Chemotherapy Effect | Immunotherapy | Tumor Mutation Burden | PD-1/L1 Inhibitor

China

GIST, Malignant | KIT Gene Mutation | KIT Exon 13 Mutation

Germany

Neoplasms | Neoplasms by Histologic Type | Urogenital Neoplasms | Neoplasms by Site | Carcinoma | Neoplasms, Glandular and Epithelial | Genital Neoplasms, Female | Ovarian Diseases | Adnexal Diseases | Carcinoma, Ovarian Epithelial | Ovarian Cancer | Angiogenesis | Genital Diseases, Female | Antineoplastic Agents | BRCA1... and other conditions

China

Acute Myeloid Leukemia With Gene Mutations

Cancer | Drug-Related Side Effects and Adverse Reactions | Cancer, Treatment-Related | EGFR Gene Mutation

Taiwan

HIV-1 Infected Patients | Fold-change Resistance | Resistance Mutations

Italy

Glioblastoma | Recurrent Glioblastoma | EGFR Gene Mutation | Supratentorial Glioblastoma | EGFR Gene Amplification | TP53 wt Allele

United States

Kidney Cancer | Renal Cell Carcinoma | ALK Gene Mutation | MET Gene Mutation | HLRCC | Renal Tumor Histology | Cutaneous Leiomyoma | BAP1 Tumor Predisposition Syndrome | VHL Syndrome | Birt-Hogg-Dube Syndrome | Familial Renal Cancer | FLCN Gene Mutation | FH Gene Mutation | Cutaneous Leiomyomata With Uterine Leiomyomata

China

Breast Neoplasms | Breast Diseases | Antineoplastic Agents | Aromatase Inhibitors | Neoplasms, Breast | Hormone Receptor Positive Breast Carcinoma | ESR1 Gene Mutation

Italy

Amyotrophic Lateral Sclerosis (ALS) | Mutation in the Superoxide Dismutase-1 (SOD1) Gene

Recurrent Glioma | Low-grade Glioma | Glioma, Malignant | IDH2 Gene Mutation | IDH1 Mutation

United States

Lung Neoplasms | EGFR Gene Mutations

Korea, Republic of

HER2 Gene Mutation

China

Gene Mutation in Infantile Onset Diabetes Mellitus

Egypt

Cancer | Lung Cancer Metastatic | MET Gene Mutation

Korea, Republic of

Fatigue | Overweight | Lynch Syndrome | Chronic Lymphocytic Leukemia | BRCA1 Gene Mutation | BRCA2 Gene Mutation | Breast Carcinoma | Cancer Survivor | Ovarian Carcinoma | Health Status Unknown | Body Mass Index 25 or Greater

United States

Full Gene Sequences of c-KIT、PDGFRA and DOG1 Are Analyzed With the Screening-sequencing Approach | Investigate the Characteristics and Variations Associated With the Different Gene Mutations of c-KIT、PDGFRA and DOG1 in GIST Patients

Hereditary Breast and Ovarian Cancer Syndrome | Adult Solid Neoplasm | BRCA1 Mutation Carrier | BRCA2 Mutation Carrier

United States

Breast Cancer | Genetic Predisposition | BRCA Mutation | Occult Cancer

Pakistan

Lung Cancer Metastatic | EGFR Gene Mutation

United States

Acute Myeloid Leukemia | Juvenile Myelomonocytic Leukemia | Acute Lymphoblastic Leukemia | AML | Acute Leukemia | Neurofibromatosis 1 | Hematologic Malignancy | Myelodysplasia | Minimal Residual Disease | Chromosome Abnormality | Monosomy 7 | Remission | Somatic Mutation | Cytogenetic Abnormality | TP53 | Fetal Hemoglobin | Intrachromosomal Amplification of Chromosome... and other conditions

United States

Non-Small Cell Lung Cancer | KRAS Gene Mutation | Advanced or Metastatic Solid Tumors Irrespective of Gene Alterations

United States

Breast Cancer | Ovarian Cancer | BRCA1 Mutation | BRCA2 Mutation | Life Style | Cadmium Exposure

Italy

Ovarian Cancer | Fallopian Tube Cancer | BRCA1 Mutation | BRCA2 Mutation | High Grade Serous Carcinoma | Primary Peritoneal Carcinoma | Carcinosarcoma, Ovarian

United Kingdom

Thyroid Cancer | Anaplastic Thyroid Cancer | BRAF Gene Mutation | BRAF Mutation-Related Tumors

United States

Breast Cancer | Gastric Cancer | Cancer Gene Mutation

United States

Metastatic Breast Cancer | Triple Negative Breast Cancer | PD-L1 Gene Mutation

Italy

EGFR Gene Mutation | Tyrosine Kinase Mutation | Non-Small Cell Adenocarcinoma

Mexico

Heart Failure | Lamin A/C Gene Mutation | Laminopathy

Italy

Chondrosarcoma | IDH1 Gene Mutation | Chondrosarcoma, Grade 2 | Chondrosarcoma, Grade 3

United States

VHL Gene Mutation | Polycythemia; Familial | Erythrocytosis; Familial | HIF-2alpha Erythrocytosis | PHD2 Erythrocytosis | Chuvash Erythrocytosis

HNSCC | HRAS Gene Mutation

United States, Belgium, Spain, United Kingdom, Taiwan, Denmark, Korea, Republic of, Netherlands, Thailand, Germany, Malaysia, Austria, Italy, Greece, Australia, Norway

Advanced Breast Cancer | ER-positive Breast Cancer | HER2-negative Breast Cancer | ESR1 Gene Mutation

Advanced Solid Malignancies | Breast Cancer - ER+, HER2 - | Breast Cancer - ER+, HER2-, PIK3CA Gene Mutation

United States, United Kingdom

Breast Cancer | Triple Negative Breast Neoplasms | HRpos Breast Neoplasms | BRCA 1 /2 and / or HRD

Germany

Lymphoma | Lung Neoplasms | Tuberculosis | EGF-R Positive Non-Small Cell Lung Cancer | Sarcoidosis | Mediastinal Lymphadenopathy | Hilar Lymphadenopathy | ROS1 Gene Mutation | PDL1 Gene Mutation | ALK Translocation

Italy

Ductal Breast Carcinoma in Situ | BRCA1 Mutation Carrier | BRCA2 Mutation Carrier | Atypical Ductal Breast Hyperplasia | Lobular Breast Carcinoma in Situ

United States

Metastatic Melanoma | BRAF Gene Mutation

United States

Non-small Cell Lung Cancer | EGFR Gene Mutation | EGFR-TKI Resistant Mutation

Colorectal Cancer | Pancreatic Cancer | Thyroid Carcinoma | Solid Tumor, Adult | Malignant Melanoma | Non-Small Cell Lung Carcinoma | BRAF Gene Mutation | Gliomas, Malignant | Ras (Kras or Nras) Gene Mutation | CRAF Gene Mutation

United States

Esophageal Cancer | Radiation Exposure | Gene Mutation-Related Cancer

China

Metastatic Colorectal Cancer | PIK3CA Gene Mutation

Korea, Republic of

ALS Caused by Superoxide Dismutase 1 (SOD1) Mutation

United States, Canada, Italy, Belgium, New Zealand, Japan, France, Germany, United Kingdom

Colon Cancer | Chemotherapy Effect | Chemotherapeutic Toxicity | MTHFR Gene Mutation

Costa Rica

AML With Gene Mutations

Australia

Breast Cancer | Ovarian Cancer | Prostate Cancer | Pancreas Cancer | BRCA1 Mutation | BRCA-Mutated Ovarian Carcinoma | BRCA-Associated Breast Carcinoma | HRD Positive Advanced Ovarian Cancer

United States

Lynch Syndrome | Colon Adenoma | Colon Carcinoma | MLH1 Gene Mutation | MSH2 Gene Mutation

United States

Lung Cancer, Non-small Cell | Circulating Tumor DNA | EGFR Gene Mutation | EGFR-TKI Resistant Mutation | Primary Resistance

China