Clinical Trials on BRCA Gene Rearrangement
Total 869 results
-
Roswell Park Cancer InstituteCelgeneWithdrawnRecurrent Acute Myeloid Leukemia | Refractory Acute Myeloid Leukemia | IDH2 Gene Mutation | Blasts Under 5 Percent of Peripheral Blood White Cells | Bone Marrow Blasts Decreased by 50 Percent or More Compared to Pretreatment LevelUnited States
-
National Cancer Institute (NCI)Active, not recruitingRecurrent Breast Carcinoma | Metastatic Triple-Negative Breast Carcinoma | Metastatic Malignant Neoplasm in the Brain | Stage IV Breast Cancer AJCC v6 and v7 | Metastatic Breast Carcinoma | Metastatic BRCA-Associated Breast CarcinomaUnited States, Puerto Rico
-
Northwestern UniversityNational Cancer Institute (NCI)RecruitingSarcoma | Cervical Cancer | Ovarian Cancer | Fallopian Tube Cancer | Vulvar Cancer | Endometrial Cancer | Vaginal Cancer | Hereditary Breast/Ovarian Cancer (brca1, brca2) | Uterine LeiomyomataUnited States
-
Shandong Provincial HospitalRecruitingMantle Cell Lymphoma | Diffuse Large B-cell Lymphoma | High Grade B-Cell Lymphoma, Not Otherwise Specified | High Grade B-Cell Lymphoma With MYC and BCL2 and/or BCL6 Rearrangements | B-cell NonHodgkin LymphomaChina
-
All India Institute of Medical Sciences, New DelhiVardhman Mahavir Medical College And Safdarjung Hospital; Institute of Human... and other collaboratorsNot yet recruitingAphasia, Broca | Stroke Rehabilitation
-
University of CalgaryCompletedStroke | Aphasia, Non-fluentCanada
-
Peloton Therapeutics, Inc., a subsidiary of Merck...Active, not recruitingVHL - Von Hippel-Lindau Syndrome | VHL Gene Mutation | VHL Syndrome | VHL Gene Inactivation | VHL-Associated Renal Cell Carcinoma | VHL-Associated Clear Cell Renal Cell CarcinomaUnited States, Denmark, United Kingdom, France
-
Daping Hospital and the Research Institute of Surgery...Not yet recruitingNon Small Cell Lung Cancer | Non Small Cell Lung Cancer Stage IIIB | EGFR Gene Mutation | Non-small Cell Lung Cancer Stage IV
-
Daping Hospital and the Research Institute of Surgery...Not yet recruitingNon Small Cell Lung Cancer | EGFR Gene Mutation | Non-small Cell Lung Cancer Stage IV | Non Small Cell Lung Cancer Stage IIIA
-
National Cancer Institute (NCI)Active, not recruitingKRAS Gene Mutation | Recurrent Lung Non-Small Cell Carcinoma | Stage IV Lung Non-Small Cell Cancer AJCC v7United States
-
CENTOGENE GmbH RostockEnrolling by invitationHereditary Diseases | FXN Gene | FRDALebanon
-
University of MinnesotaCompletedStroke | Brain Injuries | Aphasia | Non-fluent AphasiaUnited States
-
Henan Cancer HospitalRecruiting
-
AbbVieNo longer availableHigh Grade Serous Ovarian Cancer | Solid Tumors With Documented BRCA, BARD, or PALB or Other Acceptable DNA Mutations or Anomalies That Are Scientifically Sound | Triple Negative Breast Cancer (TNBC) | Patients Requiring Veliparib Suspension Formulation
-
Peloton Therapeutics, Inc., a subsidiary of Merck...National Institutes of Health (NIH)CompletedClear Cell Renal Cell Carcinoma | Von Hippel-Lindau Disease | Clear Cell RCC | ccRCC | VHL Gene Mutation | VHL Syndrome | VHL Gene Inactivation | VHL | Von Hippel | Von Hippel's Disease | Von Hippel-Lindau Syndrome, Modifiers ofUnited States
-
AstraZenecaMerck Sharp & Dohme LLC; Myriad Genetic Laboratories, Inc.CompletedMetastatic Adenocarcinoma of the Pancreas | Germline BRCA1/2 Mutations andUnited States, France, Italy, Spain, United Kingdom, Belgium, Canada, Germany, Korea, Republic of, Australia, Israel, Netherlands
-
Indiana UniversityBreast Cancer Research FoundationWithdrawnHigh-grade Serous Ovarian Cancer | BRCA1 Mutation | TNBC - Triple-Negative Breast CancerUnited States
-
Northwell HealthRecruitingGlioblastoma | Brain Cancer | Brain Tumor | GBM | Brain Neoplasm | Brain Neoplasm, Malignant | EGFR Gene OverexpressionUnited States
-
Arcus Biosciences, Inc.Gilead SciencesActive, not recruitingNon Small Cell Lung Cancer | Nonsquamous Nonsmall Cell Neoplasm of Lung | Non Small Cell Lung Cancer Metastatic | Sensitizing EGFR Gene MutationUnited States, Korea, Republic of, Singapore, Taiwan
-
Oncoethix GmbHCompletedTriple Negative Breast Cancer | Pancreatic Ductal Adenocarcinoma | Castrate-resistant Prostate Cancer | CRPC | NUT Midline Carcinoma | Non-small Cell Lung Cancer With Rearranged ALK Gene/Fusion Protein or KRAS Mutation
-
Australasian Leukaemia and Lymphoma GroupNot yet recruitingHigh-grade B-cell Lymphoma | DLBCL - Diffuse Large B Cell Lymphoma | High Grade B-Cell Lymphoma With MYC and BCL2 or BCL6 Rearrangements | DLBCL, Nos Genetic Subtypes | High Grade B-Cell Lymphoma, Not Otherwise Specified | Follicular Large Cell Lymphoma, Relapsed | Follicular Large Cell Lymphoma
-
Shandong Provincial HospitalRecruitingMantle Cell Lymphoma | Diffuse Large B Cell Lymphoma | B-cell Non Hodgkin Lymphoma | High Grade B-Cell Lymphoma, Not Otherwise Specified | High Grade B-Cell Lymphoma With MYC and BCL2 and/or BCL6 RearrangementsChina
-
Instituto do Cancer do Estado de São PauloServierRecruitingAcute Lymphoid Leukemia | Chemotherapeutic Toxicity | Minimal Residual Disease | Gene AbnormalityBrazil
-
Enliven TherapeuticsRecruitingHER2-positive Metastatic Breast Cancer | HER2 Gene Mutation | HER2 Mutant Non-small Cell Lung Cancer | HER2 AmplificationSpain, United States, Korea, Republic of, Taiwan, Italy, Australia, France
-
Children's Hospital of Chongqing Medical UniversityRecruiting
-
M.D. Anderson Cancer CenterNational Cancer Institute (NCI); Genentech, Inc.RecruitingAcute Myeloid Leukemia | Therapy-Related Acute Myeloid Leukemia | Hematologic and Lymphocytic Disorder | Acute Myeloid Leukemia in Remission | FLT3 Gene Mutation | Minimal Residual Disease PersistenceUnited States
-
Centre Leon BerardCompletedGastrointestinal Stromal Tumors | Resected Gastrointestinal Stromal Tumors | Non-metastatic | High Risk of Recurrence | KIT Gene MutationFrance
-
TESS Research FoundationStanford UniversityEnrolling by invitationEpilepsy | Movement Disorders | Rare Diseases | Genetic Disorder | Citrate Transporter Deficiency | SLC13A5 Deficiency | EIEE25 | Kohlschutter-Tonz Syndrome (Non-ROGDI) | 17p13.1 Deletions Confined to SLC13A5 Gene | Citrate Transporter DisorderUnited States
-
Betta Pharmaceuticals Co., Ltd.UnknownNon Small Cell Lung Cancer Stage IIIB | EGFR Gene Mutation | Non Small Cell Lung Cancer Stage IIIAChina
-
Sheba Medical CenterAstraZenecaSuspendedCarcinoma, Non-Small-Cell Lung | Genes, erbB-1Israel
-
Rutgers, The State University of New JerseyNational Cancer Institute (NCI)TerminatedAcute Lymphoblastic Leukemia | Mantle Cell Lymphoma | Non-Hodgkin Lymphoma | Myelodysplastic Syndrome | Plasma Cell Myeloma | Recurrent Diffuse Large B-Cell Lymphoma | Refractory Diffuse Large B-Cell Lymphoma | Minimal Residual Disease | Therapy-Related Acute Myeloid Leukemia | Therapy-Related Myelodysplastic... and other conditionsUnited States
-
National Cancer Institute (NCI)CompletedRecurrent Fallopian Tube Carcinoma | Recurrent Ovarian Carcinoma | Recurrent Primary Peritoneal Carcinoma | Breast Carcinoma | Ovarian Carcinoma | Pancreatic Carcinoma | Prostate Carcinoma | Recurrent Breast Carcinoma | Estrogen Receptor Negative | HER2/Neu Negative | Progesterone Receptor Negative | Triple-Negative... and other conditionsUnited States
-
Associazione Italiana per lo Studio del PancreasRecruitingLynch Syndrome | BRCA1 Mutation | BRCA2 Mutation | Familial Pancreatic Cancer | Hereditary Pancreatitis | Peutz-Jeghers Syndrome | FAMMM - Familial Atypical Mole Malignant Melanoma SyndromeItaly
-
Beijing Neurosurgical InstituteNot yet recruitingGlioma | Non-fluent Aphasia
-
Assiut UniversityCompletedNon Fluent Aphasia in Subacute Stroke
-
AstraZenecaMerck Sharp & Dohme LLC; European Network of Gynaecological Oncological Trial... and other collaboratorsActive, not recruitingRelapsed Ovarian Cancer | Following Complete or Partial Response to Platinum Based Chemotherapy | Platinum Sensitive | BRCA MutatedKorea, Republic of, France, China, Italy, United States, Israel, United Kingdom, Canada, Japan, Germany, Brazil, Netherlands, Belgium, Poland, Australia, Russian Federation, Spain
-
zr Pharma & GmbHFoundation MedicineCompletedOvarian Cancer | Fallopian Tube Cancer | Peritoneal Cancer | Advanced Solid Tumor With Evidence of Germline or Somatic BRCAUnited States, Israel, Spain, Canada, United Kingdom
-
Academic and Community Cancer Research UnitedNational Cancer Institute (NCI)RecruitingBile Duct Adenocarcinoma | Fanconi Anemia Complementation Group Gene Mutation | Metastatic Bile Duct Carcinoma | PTEN Gene DeletionUnited States
-
Hospital Universitario La FeUnknownMalignant Hyperthermia | Polymorphisms in Genes RYR1 and CACNAS1SSpain
-
M.D. Anderson Cancer CenterRecruitingMyelodysplastic Syndrome | Recurrent Acute Myeloid Leukemia | Refractory Acute Myeloid Leukemia | Myeloproliferative Neoplasm | Acute Myeloid Leukemia With Gene MutationsUnited States
-
M.D. Anderson Cancer CenterNational Cancer Institute (NCI); Spectrum Pharmaceuticals, IncActive, not recruitingEGFR Exon 20 Mutation | ERBB2 Gene Mutation | Recurrent Lung Non-Small Cell Carcinoma | Stage IV Non-Small Cell Lung Cancer AJCC v7United States
-
Fred Hutchinson Cancer CenterNational Cancer Institute (NCI); AstraZeneca; Juno Therapeutics, Inc.; MedImmune...TerminatedRecurrent Diffuse Large B-Cell Lymphoma | Recurrent Primary Mediastinal (Thymic) Large B-Cell Lymphoma | Refractory Diffuse Large B-Cell Lymphoma | Refractory Primary Mediastinal (Thymic) Large B-Cell Lymphoma | Refractory High Grade B-Cell Lymphoma With MYC, BCL2, and BCL6 Rearrangements | Diffuse Large B-Cell Lymphoma, Not Otherwise SpecifiedUnited States
-
Baxter Healthcare CorporationRecruitingRegional Citrate Anticoagulation (RCA) | Continuous Renal Replacement Therapy (CRRT) | Acute Kidney Injury (AKI)United States
-
Massive Bio, Inc.RecruitingMelanoma | Follicular Lymphoma | Carcinoma | Myelodysplastic Syndromes | Leukemia | Cancer | Breast Cancer | Myeloproliferative Disorders | Glioblastoma | Myelofibrosis | Ovarian Cancer | Mantle Cell Lymphoma | Marginal Zone Lymphoma | Neuroendocrine Tumors | Non Small Cell Lung Cancer | COVID | Non Hodgkin Lymphoma | Cholang... and other conditionsUnited States
-
University of PennsylvaniaMemorial Sloan Kettering Cancer Center; Susan G. Komen Breast Cancer FoundationEnrolling by invitationOvarian Cancer | BRCA MutationUnited States
-
Lynkcell EuropeEnrolling by invitationBreast Cancer | Breast Neoplasms | Ovarian Neoplasms | Ovarian Cancer | HER2-positive Breast Cancer | HER2-negative Breast Cancer | HER-2 Protein Overexpression | BRCA MutationUkraine
-
AstraZenecaMerck Sharp & Dohme LLC; GOG Foundation; Myriad Genetic Laboratories, Inc.Active, not recruitingAdvanced Ovarian Cancer | Newly Diagnosed | FIGO Stage III-IV | Partial Response | Complete Response | BRCA Mutation | First Line Platinum ChemotherapyKorea, Republic of, France, Italy, United States, Israel, Canada, China, Brazil, United Kingdom, Poland, Australia, Japan, Netherlands, Russian Federation, Spain
-
University of California, San FranciscoNational Institute of Neurological Disorders and Stroke (NINDS)RecruitingStroke | Epilepsy | Hypoxic-Ischemic Encephalopathy | Neonatal Seizure | Intracranial Hemorrhage | Gene AbnormalityUnited States
-
Northwestern UniversityNational Cancer Institute (NCI)Active, not recruitingDiffuse Large B-Cell Lymphoma | Diffuse Large B-Cell Lymphoma, Not Otherwise Specified | High Grade B-Cell Lymphoma, Not Otherwise Specified | T-Cell/Histiocyte-Rich Large B-Cell Lymphoma | High Grade B-Cell Lymphoma With MYC and BCL2 and/or BCL6 Rearrangements | Diffuse Large B-Cell Lymphoma... and other conditionsUnited States
-
Pace UniversityEmory UniversityNot yet recruitingDepressive Disorder | Stroke, Acute | Movement, Abnormal | Expressive Aphasia