Clinical Trials on Bacterial Overgrowth

Total 17871 results

Hôpital Louis Mourier

Completed

Microbial and Pharmacological Assessment of Chlorhexidine

Pneumonia, Ventilator-Associated | Infection, Bacterial | Chlorhexidine | Oropharynx Abnormality | Bacterium; Agent
Laboratoires Thea

Completed

Clinical Efficacy and Safety of T1225 Versus Tobramycin 0.3 % Eye Drops in the Treatment of Purulent Bacterial Conjunctivitis of Children.

Purulent Bacterial Conjunctivitis

France
GlaxoSmithKline

Completed

Drug-drug Interaction Study of Gepotidacin

Infections, Bacterial

United States
GlaxoSmithKline
Biomedical Advanced Research and Development Authority

Completed

Pharmacokinetics (PK) Study of Gepotidacin (GSK2140944) in Adult Subjects With Varying Degrees of Hepatic Impairment and in Matched Control Subjects With Normal Hepatic Function

Infections, Bacterial

United States
GlaxoSmithKline

Terminated

A Study to Evaluate Safety, Tolerability and Pharmacokinetics of Ascending Intravenous Single Dose and Repeat Dose of GSK3342830

Infections, Bacterial

Australia
GlaxoSmithKline

Completed

Relative Bioavailability Study in Healthy Subjects (PDF112034)

Infections, Bacterial

United States
GlaxoSmithKline

Completed

A Repeat Dose Escalation Study to Investigate the Safety, Tolerability and Pharmacokinetics of GSK1322322 in Healthy Subjects

Infections, Bacterial

Australia
Catholic University of the Sacred Heart
University Hospital, Geneva; Universiteit Antwerpen; Clinical Centre of Serbia; Canisius-Wilhelmina Hospital and other collaborators

Unknown

SATURN 04 Nosocomial Acquisition Study (SATURN)

Infection Due to ESBL Bacteria | Bacterial Resistance | Infection Resistant to Multiple Drugs | Staph Aureus Methicillin Resistant Colonization

Italy, Romania, Serbia
GlaxoSmithKline

Completed

Pharmacokinetics of Gepotidacin Tablets in Adults and Adolescents Subjects

Infections, Bacterial

United States
GlaxoSmithKline

Terminated

A Three-part Study to Determine the Safety, Tolerability and Pharmacokinetics of GSK1322322 in Healthy Volunteers and Healthy Male Japanese Subjects

Infections, Bacterial

United States
GlaxoSmithKline

Completed

Amoxicillin Bioequivalence Study Brazil - Fast

Infections, Bacterial

Brazil
GlaxoSmithKline

Withdrawn

A Pharmacokinetics, Pharmacodynamics, and Safety Study of an Oral Contraceptive Containing Norethindrone and Ethinyl Estradiol When Co-administered With GSK1322322 in Healthy Adult Women

Infections, Bacterial
Bausch & Lomb Incorporated

Completed

A Study to Determine if 0.6% ISV-403 is Safe and Effective in the Treatment of Bacterial Conjunctivitis.

Acute Bacterial Conjunctivitis
Azidus Brasil

Unknown

Effectiveness Comparison Between the Drugs TOBRACORT® and TOBRADEX® in Reducing the Signs and Symptoms of Acute Bacterial Conjunctivitis

Acute Bacterial Conjunctivitis

Brazil
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Effects of Hormone Therapy on the Immune Systems of Postmenopausal Women With Chronic Infections

Atherosclerosis | Pneumonia, Bacterial | Cytomegalovirus Infections | Chlamydia Infections | Postmenopause

United States
Sir Run Run Shaw Hospital
University of Birmingham

Unknown

Gram-negative Bacilli and MRSA Screening in ICU in China

Infections, Bacterial

China
GlaxoSmithKline

Completed

Relative Bioavailability, Safety, Tolerability, Pharmacokinetics (PK) and Food Effect Study of GSK2140944 in Healthy Subjects

Infections, Bacterial

United States
GlaxoSmithKline

Completed

A Randomized, Single Blind, Placebo Controlled Study to Evaluate Safety, Tolerability, and Pharmacokinetics of Single Oral Doses and Repeat Escalating Oral Doses of GSK2251052 in Healthy Adult Subjects

Infections, Bacterial

Australia
GlaxoSmithKline

Completed

Single Dose Escalation First Time in Human PK Study

Infections, Bacterial

Australia
GlaxoSmithKline

Completed

A Study to Investigate the Safety, Tolerability and Pharmacokinetics of Oral and Intravenous GSK1322322 in Healthy Subjects

Infections, Bacterial

United States
GlaxoSmithKline

Completed

To Evaluate Plasma and Pulmonary Pharmacokinetics of GSK2140944

Infections, Bacterial

United States
GlaxoSmithKline

Completed

A Study to Assess the Relative Bioavailability of Three Formulations and Food Effect on GSK1322322 in Healthy Subjects

Infections, Bacterial

United States
GlaxoSmithKline

Completed

Retapamulin Ointment in Healthy Adults Nasally Colonized With Staphylococcus Aureus

Infections, Bacterial

United States
GlaxoSmithKline

Withdrawn

A Single Center Four Part Study in Healthy Adult Subjects to Evaluate: the Safety, Tolerability and Pharmacokinetics of a Single Oral Dose and Repeat Escalating Oral Doses of GSK945237; the Effect of Linezolid on Hematology Safety Parameters; and the Effects of GSK945237 and Moxifloxacin on QTc.

Infections, Bacterial
GlaxoSmithKline

Withdrawn

A Study to Evaluate the Effect of GSK1322322 on Cardiac Conduction as Assessed by 12-lead Electrocardiogram in Healthy Volunteers

Infections, Bacterial
King Faisal University

Suspended

In Vitro Activity of Tigecycline Among Key Bacterial Pathogens Exhibiting Multidrug Resistance

Infections, Bacterial

Saudi Arabia
Emergent BioSolutions
GlaxoSmithKline; Department of Health and Human Services; Centers for Disease...

Not yet recruiting

Clinical Benefit, Safety and PK of Raxibacumab in Subjects Exposed to Bacillus Anthracis

Infections, Bacterial
GlaxoSmithKline

Completed

To Assess Bioavailability, Food Effect and Pharmacokinetics of Gepotidacin Tablets: A Phase I, Single-Dose, 2 Part Study in Healthy Subjects.

Infections, Bacterial

United States
GlaxoSmithKline

Completed

Bioequivalence Study Between SKF101804 Cefixime 200 Milligram (mg)/5 Milliliter (mL) Suspension Versus Cefixime 200 mg/5 mL Suspension Reference Product in Healthy Adult Subjects Under Fasting Conditions

Infections, Bacterial

South Africa
GlaxoSmithKline

Completed

To Evaluate Safety, Tolerability, Pharmacokinetics, And Food Effect Of Single Doses Of GSK945237 In Healthy Subjects

Healthy Subjects | Infections, Bacterial

Australia
Laboratorios Sophia S.A de C.V.

Completed

Safety and Efficacy of PRO-157 vs Moxifloxacin vs Gatifloxacin in Patients With Bacterial Conjunctivitis (Pazufloxacin) (Pazufloxacin)

Bacterial Conjunctivitis

Mexico
Kurobe LLC

Completed

Safety and Efficacy of Vancomycin Ophthalmic Ointment in Patients With Moderate to Severe Bacterial Conjunctivitis

Bacterial Conjunctivitis

United States
Alcon Research

Completed

Moxifloxacin AF Ophthalmic Solution for Treatment of Bacterial Conjunctivitis

Bacterial Conjunctivitis
Alcon Research

Completed

AL-15469A for the Treatment of Bacterial Conjunctivitis

Bacterial Conjunctivitis

United States
Bausch & Lomb Incorporated

Terminated

Clinical and Microbial Efficacy of Besifloxacin Ophthalmic Suspension, 0.6% in the Treatment of Bacterial Conjunctivitis

Bacterial Conjunctivitis

United States
Bausch & Lomb Incorporated

Terminated

Besifloxacin Ophthalmic Suspension Verses Gatifloxacin Ophthalmic Solution in Neonates With Bacterial Conjunctivitis

Bacterial Conjunctivitis

United States
Bausch & Lomb Incorporated

Completed

Efficacy of Besifloxacin Ophthalmic Suspension in the Treatment of Bacterial Conjunctivitis

Bacterial Conjunctivitis

United States
Allergan

Completed

A Study of the Safety and Efficacy of Gatifloxacin in Patients With Bacterial Conjunctivitis

Bacterial Conjunctivitis

United States
Alcon Research

Completed

AL-15469A for the Treatment of Bacterial Conjunctivitis

Bacterial Conjunctivitis

United States
Laser Microsurgery Centre, Poland
Katedra I Klinika Okulistyki II Wydz. Lek. AM w Warszawie,; University Hospital... and other collaborators

Completed

Study of Efficacy of Levofloxacin 0.5% Ophthalmic Solution Administered Three Times a Day for Bacterial Conjunctivitis

Bacterial Conjunctivitis

Poland
GlaxoSmithKline
Parexel

Completed

Bioequivalence Study Between GR37547 500 Milligrams (mg) Tablet Versus Ciprofloxacin 500 mg Tablet Reference Product in Healthy Adult Subjects

Infections, Bacterial

South Africa
GlaxoSmithKline

Withdrawn

A Bioequivalence Study of SKF101804 Cefixime Versus Cefixime Reference Formulation in Healthy Adults Under Fasting Conditions

Infections, Bacterial
GlaxoSmithKline

Completed

Bioavailability Of Flucloxacillin Capsules (250 mg and 500 mg)

Infections, Bacterial

Germany
GlaxoSmithKline

Completed

WEUKBRE5555: IMI PROTECT(Work Package 2): Liver Injury & Antibiotics

Infections, Bacterial
Universidad del Norte

Unknown

Piperacillin/Tazobactam Versus Carbapenems in Non-bacteremic UTI Due to -ESBL-producing Enterobacteriaceae (CAPITIS)

Urinary Tract Infections | Enterobacteriaceae Infections | Clinical Trial | Carbapenem | Klebsiella Pneumoniae Infection | Infection Due to ESBL Bacteria | Escherichia Coli Infection | Drug Resistance, Bacterial

Colombia
Murdoch Childrens Research Institute
Royal Children's Hospital; Peter MacCallum Cancer Centre, Australia

Not yet recruiting

A Trial of Targeted Therapies for Patients With Slow-Flow or Fast-Flow Vascular Malformations (TARGET-VM)

Arteriovenous Malformations | Vascular Malformations | MAP2K1 Gene Mutation | PIK3CA-related Overgrowth Spectrum | Vascular Anomalies | Lymphangioma | Lymphatic Malformation | KRAS G12D | Venous Malformation | Vascular Anomaly | KRAS G12C | PI3K Gene Mutation | Slow-Flow Vascular Malformation | Fast-Flow Vascular... and other conditions

Australia
Institut National de la Santé Et de la Recherche...

Recruiting

National Evaluation of Patients With PIK3CA-Related Overgrowth Spectrum (PROS) (COSY)

Vascular Malformations | PIK3CA-related Overgrowth Spectrum | Megalencephaly | Lymphatic Malformation | CLOVES Syndrome | Venous Malformation | Klippel Trenaunay Syndrome | MCAP | Macrodactyly

France
IVIEW Therapeutics Inc.

Completed

Trial to Evaluate the Efficacy and Safety of IVIEW-1201 in Acute Bacterial Conjunctivitis

Acute Bacterial Conjunctivitis

China
Bausch & Lomb Incorporated

Completed

A Study to Investigate the Safety and Efficacy of BOL-303224 in the Treatment of Bacterial Conjunctivitis

Acute Bacterial Conjunctivitis
NovaBay Pharmaceuticals, Inc.

Completed

Efficacy and Safety of Auriclosene (NVC-422) in the Treatment of Bacterial Conjunctivitis (BACTOvation™)

Bacterial Conjunctivitis

United States

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