Clinical Trials on Beta Cell Dysfunction

Total 39510 results

Shanghai 10th People's Hospital

Completed

Related Mechanisms of RBP4 in Glycolipid Metabolism

Beta Cell Dysfunction

China
Amsterdam UMC, location VUmc
National Research Council, Institute of Biomedical Engineering

Completed

PREDnisolone-induced Beta-cell Dysfunction Prevented by EXenatide (PREDEX)

Glucocorticoid-induced Glucometabolic Abnormalities | Glucocorticoid-induced Beta-cell Dysfunction

Netherlands
University of British Columbia

Completed

Evaluation of Low-cost Techniques for Detecting Sickle Cell Disease and β-thalassemia in Nepal and Canada

Sickle Cell Disease | Beta-Thalassemia | Sickle Cell Trait | Sickle Cell-Beta Thalassemia | Sickle Cell-SS Disease

Canada, Nepal
M.D. Anderson Cancer Center

Withdrawn

Pre-transplant Immunosuppression and Donor Stem Cell Transplant for the Treatment of Severe Hemoglobinopathies

Sickle Cell Disease | Sickle Beta Thalassemia | Beta Thalassemia Major | Sickle Cell-SS Disease | Sickle Beta 0 Thalassemia | Sickle Beta Plus Thalassemia

United States
National Heart, Lung, and Blood Institute (NHLBI)

Enrolling by invitation

Investigating the Mechanistic Effects of Mitapivat in Subjects With Sickle Cell Disease

Sickle Cell Anemia | Sickle Beta Thalassemia | Sickle Cell Thalassemia | Sickle Beta Zero Thalassemia | Sickle Cell Pain | Hbss | Hbsc | Sickle Cell Syndrome Variant

United States
Pfizer's Upjohn has merged with Mylan to form Viatris...

Completed

A Study Evaluating the Efficacy and Safety of Sildenafil in Patients With Erectile Dysfunction Receiving Hemodialysis

Hemodialysis | Erectile Disfunction

Brazil
Vertex Pharmaceuticals Incorporated
CRISPR Therapeutics

Enrolling by invitation

A Long-term Follow-up Study in Participants Who Received CTX001

Hematologic Diseases | Genetic Diseases, Inborn | Sickle Cell Disease | Hemoglobinopathies | Sickle Cell Anemia | Thalassemia | Beta-Thalassemia

United States, Canada, Italy, United Kingdom, Germany
Vertex Pharmaceuticals Incorporated
CRISPR Therapeutics

Recruiting

Evaluation of Efficacy and Safety of a Single Dose of CTX001 in Participants With Transfusion-Dependent β-Thalassemia and Severe Sickle Cell Disease

Hematologic Diseases | Genetic Diseases, Inborn | Sickle Cell Disease | Hemoglobinopathies | Sickle Cell Anemia | Thalassemia | Beta-Thalassemia

United States, Italy, Germany, Saudi Arabia
Kenneth Ataga, MD
Augusta University

Completed

Hepcidin Levels in Sickle Cell Disease (SCD)

Sickle Cell Anemia | Sickle - Beta Thalassemia
Nova Laboratories Limited

Completed

Pharmacokinetics of Oral Hydroxyurea Solution (HUPK)

Sickle Cell Disease | Sickle Cell Hemoglobin C | Sickle Cell-beta-thalassemia | Sickle-Cell; Hemoglobin Disease, Thalassemia

United Kingdom, Jamaica
National Heart, Lung, and Blood Institute (NHLBI)

Not yet recruiting

Study to Evaluate the Safety and Tolerability of Escalating Doses of Fostamatinib in Subjects With Stable Sickle Cell Disease

Sickle Cell Disease | Sickle Cell Disorders | Hb-SS Disease | Hemoglobin S | Disease Sickle Cell Anemia | Hemoglobin Beta Thalassemia Disease

United States
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Cord Blood Transplantation for Sickle Cell Anemia and Thalassemia

Hematologic Diseases | Anemia, Sickle Cell | Beta-Thalassemia | Hematopoietic Stem Cell Transplantation

United States, Canada
Phoenicia BioScience
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

The BENeFiTS Trial in Beta Thalassemia Intermedia (PB04-001)

Sickle Cell Disease | Beta Thalassemia Intermedia

United States, Canada
Northwell Health

Completed

HSCT For Patients With High Risk Hemoglobinopathies Using Reduced Intensity

Sickle Cell Disease | Beta Thalassemia-Major

United States
Editas Medicine, Inc.

Not yet recruiting

A Long-Term Follow-Up Study of Participants With Sickle Cell Disease or Transfusion Dependent β-Thalassemia Who Received EDIT-301

Sickle Cell Disease | Hemoglobinopathies | Transfusion-dependent Beta-Thalassemia
Emory University
Patient-Centered Outcomes Research Institute

Completed

Decision Aid for Therapeutic Options In Sickle Cell Disease

Sickle Cell Disease | Sickle Cell Anemia | Hemoglobin SC | Hemoglobin SS | Hemoglobin Beta Thalassemia

United States
Hillel Yaffe Medical Center

Unknown

Prevalence Of Microalbuminuria Among Children Suffering From Sickle Cell Nephropathy and Sickle Cell/Beta-Thalassemia

Sickle Cell Anemia | Beta-Thalassemia | Microalbuminuria
Assiut University

Not yet recruiting

Pumilio1 (PUM1) Expression, Sickle Cell Anemia, β-thalassemia Intermedia

Sickle Cell Disease, Beta Thalassemia Intermedia
National Heart, Lung, and Blood Institute (NHLBI)

Recruiting

Addition of JSP191 (C-kit Antibody) to Nonmyeloablative Hematopoietic Cell Transplantation for Sickle Cell Disease and Beta-Thalassemia

Sickle Cell Anemia | Beta Thalassemia

United States
Columbia University

Active, not recruiting

Stem Cell Transplant in Sickle Cell Disease and Thalassemia

Sickle Cell Disease | Beta Thalassemia

United States
Memorial Sloan Kettering Cancer Center

Recruiting

A Study of Immune Suppression Treatment for People With Sickle Cell Disease or β-Thalassemia Who Are Going to Receive an Allogeneic Hematopoietic Cell Transplantation (HCT)

Sickle Cell Disease | Thalassemia | Thalassemia, Beta

United States
National Institute of Allergy and Infectious Diseases...

Recruiting

Collection of Human Biospecimens for Basic and Clinical Research Into Globin Variants

Malaria | Sickle Cell Disease | Alpha and Beta Thalassemia | Human Physiology

United States
bluebird bio

Completed

A Study Evaluating the Safety and Efficacy of LentiGlobin BB305 Drug Product in β-Thalassemia Major (Also Referred to as Transfusion-dependent β-Thalassemia [TDT]) and Sickle Cell Disease

Sickle Cell Disease | Beta-Thalassemia Major

France
Augusta University
Yale University; University of Alabama at Birmingham; Tufts University

Unknown

Vitamin K and Glucose Metabolism in Adults at Risk for Diabetes (Vita-K 'n' Adults Study)

Obesity | Insulin Resistance | Insulin Sensitivity | Prediabetes | Beta-Cell Dysfunction

United States
Paul Szabolcs

Recruiting

T-Cell Depleted Alternative Donor Bone Marrow Transplant for Sickle Cell Disease (SCD) and Other Anemias

Sickle Cell Anemia | Diamond-blackfan Anemia | Beta-thalassemia Major

United States
National Heart, Lung, and Blood Institute (NHLBI)
National Institutes of Health Clinical Center (CC); National Cancer Institute...

Recruiting

Nonmyeloablative Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Sickle Cell Disease and Beta-thalassemia in People With Higher Risk of Transplant Failure

Stem Cell Transplantation | Sickle Cell Disease | Thalassemia | Graft vs Host Disease

United States
Cyprus Institute of Neurology and Genetics

Recruiting

Study of the Role of Genetic Modifiers in Hemoglobinopathies (INHERENT)

Sickle Cell Disease | Hemoglobinopathies | Thalassemia Alpha | Thalassemia, Beta

United States, Denmark, Spain, Belgium, Portugal, Congo, The Democratic Republic of the, Greece, Argentina, Brunei Darussalam, Cyprus, Israel, Italy, Nigeria, Malaysia, Angola, Pakistan
Sangamo Therapeutics

Enrolling by invitation

Long - Term Follow Up of Sickle Cell Disease and Beta-thalassemia Subjects Previously Exposed to BIVV003 or ST-400.

Blood and Lymphatic Diseases

United States
Celgene

Terminated

Study to Determine the Safety and Tolerability of Sotatercept (ACE-011) in Adults With Beta( β)- Thalassemia.

Beta Thalassemia Intermedia | Beta Thalassemia Major

France, United Kingdom, Italy, Greece
Ain Shams University

Unknown

Study Of Efficacy,Safety of Combined Deferasirox and Deferiprone Versus Combined Deferiprone and Desferal In Conditions of Iron Overload

Sickle Cell Disease | Beta-thalassemia Major | Iron Hemosiderosis

Egypt
Bayer

Completed

Levitra (Vardenafil, BAY38-9456) Partner Satisfaction Study II

Sexual Dysfunction | Male Erectile Dysfunction

Belgium, Italy, France, Germany, Spain, Netherlands, South Africa
Mental Health Services in the Capital Region, Denmark
Den Owesenske Fond

Unknown

Mindfulness as Treatment of Sexological Problems

Sexual Dysfunction | Sexual Dysfunctions, Psychological | Sexual Dysfunctions, Physiological

Denmark
Universidad Francisco de Vitoria
University of Seville; University of Greenwich

Completed

Ingestion of Beta-alanine Effects in Well-trained Tennis Players (BETA_TENNIS)

Beta-alanine | Placebo

Spain
Cairo University

Completed

Botulinum Toxin for Erectile Dysfunction

Sexual Dysfunction | Erectile Dysfunction

Egypt
Singapore Institute for Clinical Sciences
DSM Nutritional Products, Inc.

Completed

Beta-cryptoxanthin Supplement: Absorption and Function (BETA+)

Beta-cryptoxanthin Supplementation

Singapore
Sun Yat-sen University
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Unknown

The Early Diagnosis and Warning Role of Erectile Dysfunction

Erectile Dysfunction | Endothelial Dysfunction

China
Brown University
National Institute of General Medical Sciences (NIGMS)

Recruiting

Beta Events and Sensory Perception

Beta Rhythm | Tactile Perception

United States
Groupe Hospitalier Paris Saint Joseph

Recruiting

Evaluation of Pharmacokinetic / Pharmacodynamic and Tolerance Assessment of Dermal Administration of Beta-lactams in the Elderly (BETALACUTANE)

Beta-Lactams | Aged Subject

France
IVI Santiago de Chile
Pontificia Universidad Catolica de Chile; University of Chile

Unknown

RCTrial to Test Low Intensity Shockwave Treatment in Patients With Mild/Moderate Erectile Dysfunction

Erectile Dysfunction | Endothelial Dysfunction

Chile
The Hospital for Sick Children
Sunnybrook Health Sciences Centre; University of Toronto; University of Guelph

Completed

Mechanisms of Inflammation, Immunity, Islet Cell and Intestinal Hormone Changes in Youth at Risk for Diabetes (MI4D)

Inflammation | Obesity | Insulin Resistance | PreDiabetes | Adolescent Obesity | Immunity | Gut Microbiome | Gut Hormones | Beta Cell Dysfunction | Metabolic Problems

Canada
Vancouver Coastal Health

Recruiting

Providing Insight Into and Mindfulness for Situational Erectile Dysfunction (PRIMED)

Situational Erectile Dysfunction

Canada
University of Virginia
DIREX SYSTEMS CORPORATION

Withdrawn

Low Intensity Linear Shockwave Therapy for Erectile Dysfunction

Vasculogenic Erectile Dysfunction
Johns Hopkins University

Terminated

Assessment of Penile Vibratory Stimulation Using the Viberect in Men With Mild-Moderate ED

Organic Erectile Dysfunction

United States
University of Miami
DIREX SYSTEMS CORPORATION

Completed

Safety and Efficacy of Low Intensity Shockwave for the Treatment of Erectile Dysfunction

Vasculogenic Erectile Dysfunction

United States
Alza Corporation, DE, USA

Completed

An Open-Label Study of the Long-Term Safety of Dapoxetine HCl in the Treatment of Rapid Ejaculation

Sexual Dysfunction | Erectile Dysfunction | Ejaculation
Novartis Pharmaceuticals

Completed

Post Hematopoietic Stem Cell Transplantation

Iron Overload After Hematopoietic Stem Cell Transplantation (HSCT) in Patients With Beta-thalassemia Major

Turkey
Cairo University

Completed

Intracavernosal Injection of Botulinum Toxin Type A in the Treatment of Vascular Erectile Dysfunction

Vasculogenic Erectile Dysfunction

Egypt
Initia

Terminated

Safety and Efficacy Associated With Treating Erectile Dysfunction Patients With Low Intensity Shockwaves by Renova

Vasculogenic Erectile Dysfunction

Israel
Initia

Completed

Low Intensity Extracorporeal Shockwave Therapy (LI-ESWT) by 'Renova' for Patients With Erectile Dysfunction

Vasculogenic Erectile Dysfunction

Israel
Initia

Completed

Low Intensity Extracorporeal Shockwave Therapy for Patients With Erectile Dysfunction (LISW)

Vasculogenic Erectile Dysfunction

Czech Republic, Lithuania, Netherlands, Palestinian Territories, Occupied

Clinical Trials on Beta Cell Dysfunction

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Bosnia & Herzegovina

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations