Clinical Trials on Biliary Obstruction

Total 13745 results

Xijing Hospital of Digestive Diseases

Recruiting

Fenofibrate Combined With Ursodeoxycholic Acid in Subjects With Primary Biliary Cholangitis

Primary Biliary Cholangitis

China
University of Milano Bicocca
Intercept Pharmaceuticals; Laboratoires Mayoly Spindler

Recruiting

National Database on Primary Biliary Cholangitis (PBC322)

Primary Biliary Cholangitis

Italy
Fondazione Epatocentro Ticino

Recruiting

Swiss Primary Biliary Cholangitis Cohort Study

Liver Cirrhosis, Biliary

Switzerland
Xijing Hospital of Digestive Diseases

Recruiting

Fenofibrate for Patients With Primary Biliary Cirrhosis Who Had An Inadequate Response to Ursodeoxycholic Acid

Primary Biliary Cirrhosis

China
Intercept Pharmaceuticals

Active, not recruiting

Study of OCA in Combination With BZF Evaluating Efficacy, Safety, and Tolerability in Participants With PBC

Primary Biliary Cholangitis

Netherlands, United Kingdom, Korea, Republic of, Germany, Australia, Estonia, Belgium, France, Czechia, Croatia, Greece, Hungary, Israel, Lithuania, Norway, Poland, Spain
COUR Pharmaceutical Development Company, Inc.

Active, not recruiting

Study to Evaluate the Safety, Tolerability, PDs, and Efficacy of CNP-104 in Subjects With Primary Biliary Cholangitis

Primary Biliary Cholangitis

United States
Intercept Pharmaceuticals
Syneos Health; Global PBC Study Group; Target RWE; UK PBC Study Group

Withdrawn

A Real-World Data Study to Evaluate the Effectiveness of OCA on Hepatic Outcomes in PBC Patients (HEROES-PBC)

Primary Biliary Cholangitis

United States
Yale University
American Liver Foundation

Suspended

Mindfulness - Based Intervention in the Treatment of Fatigue in Patients With Primary Biliary Cholangitis

Primary Biliary Cholangitis

United States
The First Affiliated Hospital with Nanjing Medical...
Jiangsu HengRui Medicine Co., Ltd.

Completed

SHR-1210 in Combination With GEMOX in Patients With Advanced BTC

Cholangiocarcinoma | Biliary Tract Cancer

China
Novartis Pharmaceuticals

Completed

A Multi-part, Double Blind Study to Assess Safety, Tolerability and Efficacy of Tropifexor (LJN452) in PBC Patients

Primary Biliary Cholangitis

United States, Germany, Russian Federation, Canada, United Kingdom, Poland
Christopher Bowlus, MD
Bristol-Myers Squibb

Completed

Study of Abatacept (Orencia) to Treat Primary Biliary Cirrhosis (PBC)

Primary Biliary Cirrhosis

United States
Dr. Falk Pharma GmbH

Terminated

Ursodeoxycholic Acid Plus Budesonide Versus Ursodeoxycholic Acid Alone in Primary Biliary Cirrhosis (PBC)

Primary Biliary Cirrhosis

France, Germany
West China Hospital

Completed

The Comparison About the Response of Ursodeoxycholic Acid in Primary Biliary Cholangitis Only and Primary Biliary Cholangitis With High Immune Globulin G or Aminotransferase at West China Hospital

Primary Biliary Cholangitis

China
EA Pharma Co., Ltd.

Terminated

Study of E6011 in Japanese Subjects With Primary Biliary Cholangitis Inadequately Responding to Ursodeoxycholic Acid

Primary Biliary Cholangitis

Japan
University of California, Davis
Genentech, Inc.

Completed

Initial Study of Rituximab to Treat Primary Biliary Cirrhosis

Primary Biliary Cirrhosis

United States
George Brewer
FDA Office of Orphan Products Development

Completed

Study Comparing Tetrathiomolybdate vs Standard Treatment in Primary Biliary Cirrhosis

Primary Biliary Cirrhosis

United States
NGM Biopharmaceuticals, Inc
NGM Biopharmaceuticals Australia Pty Ltd

Completed

Phase 2 Study of NGM282 in Patients With Primary Biliary Cirrhosis

Primary Biliary Cirrhosis

United States, Australia
Janssen Research & Development, LLC

Completed

A Study of Efficacy and Safety of Ustekinumab in Patients With Primary Biliary Cirrhosis (PBC) Who Had an Inadequate Response to Ursodeoxycholic Acid

Primary Biliary Cirrhosis

United States, Canada
University of Alberta
Canadian Institutes of Health Research (CIHR); Gilead Sciences; Abbott

Completed

Highly Active Antiretroviral Therapy for Patients With Primary Biliary Cirrhosis (HAART)

Primary Biliary Cirrhosis

Canada
Beijing 302 Hospital

Unknown

Umbilical Cord Mesenchymal Stem Cells for Patients With Primary Biliary Cirrhosis

Primary Biliary Cirrhosis

China
Beijing Friendship Hospital
Beijing Trendful Kangjian Medical Information Consulting Limited Company

Completed

Safety and Efficacy of Tauroursodeoxycholic Acid Versus Ursofalk in the Treatment of Adult Primary Biliary Cirrhosis

Primary Biliary Cirrhosis

China
Richard Burt, MD
Northwestern Memorial Hospital

Withdrawn

Stem Cell Transplantation in Patients With Primary Biliary Cirrhosis

Primary Biliary Cirrhosis
Robert Chunhua Zhao, MD, PhD
Peking Union Medical College Hospital

Unknown

Efficacy and Safety Study of Allogenic Mesenchymal Stem Cells for Patients With Refractory Primary Biliary Cirrhosis (MSCsTreatPBC)

Primary Biliary Cirrhosis

China
National Center for Research Resources (NCRR)
Tufts Medical Center

Completed

Low-Dose Oral Methotrexate Versus Colchicine for Primary Biliary Cirrhosis

Liver Cirrhosis, Biliary
H. Lee Moffitt Cancer Center and Research Institute
Bayer

Completed

Single Agent Regorafenib in Refractory Advanced Biliary Cancers

Cancer of the Bile Duct

United States
Peking Union Medical College Hospital

Completed

Apatinib Plus Camrelizumab in Patients With Previously Treated Advanced Biliary Tract Cancer (ACABC)

Cholangiocarcinoma | Hepatobiliary Neoplasm | Biliary Tract Cancer | Biomarker

China
West China Hospital

Unknown

Ursodeoxycholic Acid Combined With Total Glucosides of Paeony in the Treatment of PBC With AIH Features 1

Hepatitis | Autoimmune | Primary Biliary Cholangitis

China
Xiaoli Fan

Completed

Retrospective Study About Primary Biliary Cholangitis During January 2001 to July 2016 at West China Hospital

Liver Diseases | Liver Cirrhosis | Cholangitis | Bile Duct Diseases | Cholestasis | Liver Cirrhosis, Biliary

China
Air Force Military Medical University, China

Completed

Learning Curve of Double-wire Cannulation Technique During Endoscopic Retrograde Cholangiopancreatography (ERCP)

Endoscopic Retrograde Cholangiopancreatography | Biliary Cannulation

China
Institut für Klinische Krebsforschung IKF GmbH...
AstraZeneca

Recruiting

Immunotherapy Combined With Y-90 SIRT Therapy in Advanced Stage Intrahepatic Biliary Tract Cancer (BTC)

Intrahepatic Cholangiocarcinoma

Germany
Duzce University
Cukurova University

Completed

Needle Knife Fistulotomy Versus Partial Ampullary Endoscopic Mucosal Resection for Difficult Biliary Cannulation

Common Bile Duct Calculi | Biliary Disease | Biliary Stricture | Malignant Hepatobiliary Neoplasm | Pancreatic Disease

Turkey
University of Birmingham
University Hospital Birmingham NHS Foundation Trust; Intercept Pharmaceuticals

Terminated

EXerCise Intervention in cholesTatic LivEr Disease: The EXCITED Study (EXCITED)

Primary Biliary Cholangitis

United Kingdom
University of Sao Paulo General Hospital

Completed

Development of Ursodeoxycholic Acid 300 mg at Hospital Das Clinicas of the University of São Paulo School of Medicine

Primary Biliary Cirrhosis | Ursodeoxycholic Acid

Brazil
Tongji Hospital
Gelesis, Inc.; Geneplus-Beijing Co. Ltd.; Chinese Cooperative Group of Liver... and other collaborators

Recruiting

Primary Hepatobiliary Cancer Cohort of Central China (CCGLC-002)

Hepatocellular Carcinoma | Biliary Tract Neoplasms

China
RenJi Hospital

Unknown

The Effect of Individualized Precision Therapy Programs in Patients With BTC

Biliary Tract Neoplasms

China
Minia University

Recruiting

One Session Vs Staged Management of Calcular Obstructive Jaundice

Gall Bladder Disease | Calcular Obstructive Jaundice

Egypt
Imperial College London

Completed

Initial Experience With a New Laparoscopic Based Robotically Assisted Surgical System for Cholecystectomy

Cholecystitis | Biliary Colic

United Kingdom
University of Leipzig
Hannover Medical School; RWTH Aachen University; Academisch Medisch Centrum -... and other collaborators

Recruiting

Prospective, Multicenter Cohort Study on Primary Biliary Cholangitis (PBC-Cohort)

Primary Biliary Cholangitis | PBC

Germany
National Scientific Medical Center, Kazakhstan
Eurasia Invest Ltd.; Ministry of Education and Science, Republic of Kazakhstan

Completed

Clinical Trial on the Effect of the Sublimated Mare Milk Supplement on Primary Biliary Cholangitis

Primary Biliary Cirrhosis

Kazakhstan
Newcastle-upon-Tyne Hospitals NHS Trust
Newcastle University; National Institute for Health Research, United Kingdom; Department of Health, United Kingdom

Completed

B-Cell Depleting Therapy (Rituximab) as a Treatment for Fatigue in Primary Biliary Cirrhosis (RITPBC)

Fatigue | Primary Biliary Cirrhosis

United Kingdom
Ziv Hospital

Unknown

Transient ECG Changes in Patients With Acute Biliary Disease

Acute Cholecystitis | Biliary Colic | Acute Cholangitis

Israel
Pomeranian Medical University Szczecin
Laval University

Completed

Effectiveness of S-adenosyl-L-methionine in Patients With Primary Biliary Cirrhosis

Primary Biliary Cirrhosis

Poland
Tufts Medical Center
Virginia Commonwealth University

Active, not recruiting

Effects of High Flow Nasal Cannula on Sputum Clearance in Acute Exacerbation of Chronic Obstructive Pulmonary Disease

Chronic Obstructive Pulmonary Disease | COPD Exacerbation | Airflow Obstruction

United States
Zhang Xiaofeng,MD
Zeno Therapeutics Pte. Ltd

Not yet recruiting

Early Phase I Study of Autologous T Cells (EX02 CAR-T) for Unresectable Pancreatic/Bile Duct Cancer

Pancreatic Cancer | Advanced Biliary Cancer
GeneQuantum Healthcare (Suzhou) Co., Ltd.

Recruiting

Safety of GQ1001 in Adult Patients With HER2-Positive Advanced Solid Tumors

HER2-positive Breast Cancer | HER2-positive Biliary Tract Cancer | HER2-Positive Salivary Gland Carcinomas | HER2-Positive Advanced Solid Tumor

China, Australia, United States
Norwegian University of Science and Technology
Sorlandet Hospital HF

Completed

Nasal Obstruction in Sleep Apnea Patients Compared to the General Population

Nasal Obstruction | Obstructive Sleep Apnoea Syndrome

Norway
Wake Forest University Health Sciences

Completed

Surgical Outcomes Database For Faculty of Hepatopancreatic Biliary Surgery

Pancreatic Cancer | Biliary Tract Cancer | Cancer of Liver

United States
Hamad Medical Corporation

Unknown

Indocyanine Green to Visualize Critical View of Safety During Laparoscopic Cholecystectomy for Acute Cholecystitis

Acute Cholecystitis | Acute; Cholecystitis, Choledocholithiasis | Acute Cholecystitis With Obstruction

Qatar
The University of Hong Kong

Unknown

A Study on Smoking-related Lung Function Abnormalities and Correlation With Serum Biomarkers in Chinese

Chronic Airflow Obstruction

Hong Kong
Peking Union Medical College Hospital

Completed

Lenvatinib in Patients With Previously Treated Advanced Biliary Tract Cancer (LENABC)

Cholangiocarcinoma | Biliary Tract Cancer | Targeted Therapy

China

Clinical Trials on Biliary Obstruction

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Hong Kong

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Rare Diseases

Drug Interventions

Dietary Supplements

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