Clinical Trials on Birth, Preterm in South Africa

Total 1461 results

Prisma Health-Midlands

Completed

Opiate Free Multimodal Pain Pathway in Elective Foot and Ankle Surgery: A Prospective Study

Ankle Fractures | Bunion of Unspecified Foot | Bunionette of Unspecified Foot | Hammertoe | Achilles Tendon Surgery

United States
Medical University of South Carolina
American Heart Association

Completed

Study of Effects of Sildenafil on Patients With Fontan Heart Circulation

Single Ventricle Heart Disease After Fontan Surgery

United States
University of Chicago
National Cancer Institute (NCI)

Completed

Oxaliplatin in Treating Patients With Metastatic Bladder Cancer

Bladder Cancer | Transitional Cell Cancer of the Renal Pelvis and Ureter

United States, Canada
Anchora Medical

Recruiting

Laparoscopic Primary Umbilical Hernia Repair With Routine Defect Closure Using Su2ura Approximation Device

Primary Umbilical Hernia

Israel, Slovenia
Dr. Marjon H. Cnossen MD PhD
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)

Recruiting

Brain Structure and Neurocognitive Development in Sickle Cell Disease; a Longitudinal Cohort Study (BRICK Study) (BRICK)

Sickle Cell Disease | Brain Development Abnormality

Netherlands
Medical Research Council

Completed

Fluorouracil in Treating Patients With Recurrent or Metastatic Bladder Cancer

Bladder Cancer | Transitional Cell Cancer of the Renal Pelvis and Ureter | Urethral Cancer

Canada, United Kingdom, Norway, New Zealand, Netherlands, South Africa, Brazil, Finland
CSL Limited

Completed

Ig NextGen 10% in Patients With Primary Immune Deficiency (PID)

Primary Immune Deficiency (PID)

Australia
University of Athens
University of Thessaly

Completed

Study of a Novel Technique of Mechanical Ventilation in Patients With Severe Acute Respiratory Failure (HFO-TGI-2)

Respiratory Distress Syndrome

Greece
Sheffield Teaching Hospitals NHS Foundation Trust
University of Sheffield; Sheffield Children's NHS Foundation Trust

Completed

Skin Pathology Assessment With Optical Technologies (SPOT)

Atopic Dermatitis Eczema

United Kingdom
AlgiPharma AS
AlgiPharma Australia Pty. Ltd.

Unknown

A Phase 2b Randomised, Placebo Controlled Study of OligoG in Patients With Cystic Fibrosis

Cystic Fibrosis

Australia
Sheffield Children's NHS Foundation Trust

Withdrawn

Botox Clinical Trial

Foot Deformities | Leg Length Inequality

United Kingdom
Sheffield Teaching Hospitals NHS Foundation Trust

Completed

Pilot Study of Behavioural Intervention for Nutrition in Cystic Fibrosis (PIN-CF)

Cystic Fibrosis

United Kingdom
Sheffield Teaching Hospitals NHS Foundation Trust

Recruiting

Inhaled Therapy Adherence and Outcomes to Kaftrio in Cystic Fibrosis

Cystic Fibrosis

United Kingdom
Sheffield Teaching Hospitals NHS Foundation Trust

Completed

Evaluation of a Behavioural Intervention Using App Technology in CF (EAT-CF)

Cystic Fibrosis

United Kingdom
Sheffield Teaching Hospitals NHS Foundation Trust

Completed

Using Remote Telemonitoring to Detect Early Decline in Lung Function & Streamline Clinics in Adults With Cystic Fibrosis (RIGHT-CF)

Cystic Fibrosis

United Kingdom
Arrowhead Pharmaceuticals

Completed

Study of ARO-ANG3 in Healthy Volunteers and in Dyslipidemic Patients

Dyslipidemias | Hypertriglyceridemia | Familial Hypercholesterolemia

Australia, New Zealand
Krystal Biotech, Inc.
Novotech (Australia) Pty Limited

Withdrawn

A Study of Inhaled KB407 for the Treatment of Cystic Fibrosis

Cystic Fibrosis

Australia
Sheffield Teaching Hospitals NHS Foundation Trust
University of Sheffield

Completed

Skin bioMARkers for Atopic Eczema Therapy Evaluation (SMART)

Atopic Eczema/Dermatitis (Non-Specific)

United Kingdom
Kiora Pharmaceuticals, Inc.

Recruiting

A Phase I/II Dose-escalating Study of the Safety, Tolerability and Efficacy of KIO-301 Administered Intravitreally to Patients With Retinitis Pigmentosa and Choroideremia (ABACUS) (ABACUS)

Retinitis Pigmentosa | Choroideremia

Australia
Eastern Cooperative Oncology Group
National Cancer Institute (NCI)

Completed

Docetaxel and Gemcitabine in Treating Patients With Progressive Regional or Metastatic Bladder Cancer

Bladder Cancer | Transitional Cell Cancer of the Renal Pelvis and Ureter | Urethral Cancer

United States, Puerto Rico, South Africa
Hoffmann-La Roche
Chugai Pharmaceutical

Completed

A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Prophylactic Emicizumab Versus no Prophylaxis in Hemophilia A Participants With Inhibitors (HAVEN 1)

Hemophilia A

Korea, Republic of, United States, France, Germany, Italy, South Africa, Spain, Japan, United Kingdom, Poland, Taiwan, Australia, Costa Rica, New Zealand
University of Athens

Completed

Physiological Study of Low-frequency HFO/HFO-TGI and High-frequency HFO

Acute Respiratory Distress Syndrome | Acute Cor Pulmonale

Greece
King Faisal Specialist Hospital & Research Centre...

Recruiting

To Assess the Efficacy of Early Administration of Energy Enriched and Protein Enriched Formula in Post Cardiac Repair Infants: a Randomized Controlled Trial, Comparative Study

Congenital Heart Disease in Children | Post-cardiac Surgery | Malnutrition, Infant

Saudi Arabia
Baxalta now part of Shire
Baxalta Innovations GmbH, now part of Shire

Terminated

BAX 802 in CHA With Inhibitors (CHAWI)

Hemophilia A

Netherlands, Spain, Italy, Turkey, Bulgaria, United States, Canada, Germany, Norway, Poland, Russian Federation, South Africa
Sheffield Children's NHS Foundation Trust
Sheffield Hallam University; National Institute for Health Research, United... and other collaborators

Active, not recruiting

DMD- Interactive Virtual Reality Study (DMD-IVR)

Duchenne Muscular Dystrophy

United Kingdom
University of Sydney

Unknown

Infection and Tumour Antigen Cellular Therapy (INTACT-WT1)

Leukemia, Myelocytic, Acute

Australia
Krystal Biotech, Inc.

Recruiting

A Study of KB408 for the Treatment of Alpha-1 Antitrypsin Deficiency (Serpentine-1)

Alpha 1-Antitrypsin Deficiency

United States
Medical University of South Carolina
Alpha-1 Foundation

Completed

Alpha-1 Foundation Research Registry

Alpha 1-Antitrypsin Deficiency

United States
Brigham and Women's Hospital

Completed

Study of Perfusion and Anatomy's Role in Coronary Artery (CAD) (SPARC)

Known CAD, or Intermediate-high Pretest Likelihood for CAD

United States, Canada
University Health Network, Toronto
National Cancer Institute (NCI)

Completed

Bortezomib in Treating Patients With Advanced or Metastatic Transitional Cell Cancer of the Bladder, Renal Pelvis, or Ureter

Bladder Cancer | Transitional Cell Cancer of the Renal Pelvis and Ureter

United States, Canada
University of Athens
Academy of Athens

Completed

Clinical and Biological Markers in Acute Respiratory Failure

Acute Respiratory Distress Syndrome | Ventilator-Associated Pneumonia

Greece
South West Sydney Local Health District

Recruiting

Viscoelastic Testing Guided Tissue Plasminogen Activator Treatment in Acute Respiratory Failure (VETtiPAT-ARF)

Acute Respiratory Failure | Hypercoagulability | Fibrinolysis Shutdown

Australia
Vyne Therapeutics Inc.

Completed

Safety, Pharmacokinetics and Efficacy of FMX114 Versus Vehicle in Adults With Atopic Dermatitis

Atopic Dermatitis

United States, Australia
Temple University

Completed

Ameliorating Attention Problems in Children With Sickle Cell Disease (SCD)

Sickle Cell Disease

United States
RBP4 Pty Ltd
Belite Bio, Inc

Completed

This is a Dose-finding Study Followed by 2-year Extension Study to Evaluate Safety and Tolerability of Tinlarebant in Adolescent Subjects With Stargardt Disease

Stargardt Disease

Taiwan, Australia
The Hawkins Foundation

Completed

Hip Scope Fascia-iliaca (FI) Block Study

Acetabular Labrum Tear | Hip Dysplasia | Femoroacetabular Impingement

United States
National Cancer Institute (NCI)

Recruiting

Testing the Addition of MEDI4736 (Durvalumab) to Chemotherapy Before Surgery for Patients With High-Grade Upper Urinary Tract Cancer

Renal Pelvis and Ureter Urothelial Carcinoma

United States
University of South Carolina
Centers for Disease Control and Prevention

Active, not recruiting

Phone-Based Based Walk With Ease Program for Adults With Arthritis

Arthritis | Osteoarthritis | Rheumatoid Arthritis | Lupus Erythematosus, Systemic | Fibromyalgia | Gout

United States
Pfizer

Completed

Study To Evaluate The Safety And Efficacy Of Torcetrapib/Atorvastatin In Subjects With Familial Hypercholerolemia

Hyperlipidemia | Hypercholesterolemia, Familial

Australia, Canada, United States, France, South Africa, Sweden, Norway, Denmark, Iceland
University of Athens

Recruiting

Cerebral Autoregulation and COVID-19 (CA-COVID)

COVID-19 Pneumonia | COVID-19 Acute Respiratory Distress Syndrome

Greece
National Center for Research Resources (NCRR)
Medical University of South Carolina

Completed

Genetic Study of Sitosterolemia

Lipid Metabolism, Inborn Errors | Sitosterolemia

United States
University of Athens
University of Thessaly

Terminated

High Frequency Oscillatory Ventilation for Acute Respiratory Distress Syndrome (ARDS)

Acute Respiratory Distress Syndrome

Greece
South Australian Health and Medical Research Institute
Women's and Children's Hospital, Australia; Flinders Medical Centre; Royal North... and other collaborators

Active, not recruiting

Prenatal Iodine Supplementation and Early Childhood Neurodevelopment (PoppiE)

Pregnancy Related | Neurodevelopmental Disorders | Nutrition Disorder, Fetal

Australia
Kirby Institute
National Heart, Lung, and Blood Institute (NHLBI); St Vincent's Hospital, Sydney and other collaborators

Completed

Seronegatives and Metabolic Abnormalities Protocol 2 (SAMA002): Study to Compare the Effect of Kaletra and Combivir® in HIV-Negative Healthy Subjects

Glucose Metabolism Disorders | Metabolic Diseases | HIV Infections | Cardiovascular Disease | Dyslipidemias | Lipodystrophy

Australia
Garvan Institute of Medical Research

Completed

Gut Derived Hormones, Body Composition and Metabolism in Prader-Willi Syndrome

Prader-Willi Syndrome

Australia
ADARx Pharmaceuticals, Inc.

Recruiting

Safety, Tolerability, PK, PD of ADX-324 in Healthy Volunteers and Hereditary Angioedema Patients

Hereditary Angioedema

Australia
Bioverativ Therapeutics Inc.
Swedish Orphan Biovitrum

Completed

Study to Evaluate the Safety, Efficacy, and Pharmacokinetics of Recombinant Coagulation Factor VIII Fc Fusion Protein (rFVIIIFc) in Previously Treated Pediatric Subjects With Hemophilia A (Kids ALONG)

Hemophilia A

United States, Poland, United Kingdom, Netherlands, South Africa, Hong Kong, Australia, Ireland
Medical University of South Carolina
National Institute of Neurological Disorders and Stroke (NINDS)

Completed

Safety of N-acetylcysteine in Maternal Chorioamnionitis (NAC in Chorio)

Brain Injury | Chorioamnionitis

United States
Erasmus Medical Center
Queen's University, Belfast; Cystic Fibrosis Foundation; European Cystic Fibrosis...

Active, not recruiting

COVID-19 Antibody Responses In Cystic Fibrosis (CAR-CF)

Cystic Fibrosis

Netherlands
Medical University of South Carolina

Completed

Preoperative Corticosteroid Therapy in Neonates Undergoing Cardiopulmonary Bypass

Congenital Heart Disease | Disorder of Fetus or Newborn

United States

Clinical Trials on Birth, Preterm in South Africa

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