Clinical Trials on Blood Protein Disorders

Total 201761 results

Pfizer

Completed

Study to Evaluate Safety and Tolerability of a Single Dose of PF-06741086 in Chinese Adult Participants With Severe Hemophilia

Severe Hemophilia

China
Assistance Publique Hopitaux De Marseille

Completed

Occupational Integration of Adults With Severe Haemophilia in France: a Study Based on the FranceCoag Cohort (INTHEMO)

Severe Haemophilia

France
Novo Nordisk A/S

Terminated

Evaluation of Safety Following Immune Tolerance Induction Treatment With Turoctocog Alfa in Patients With Haemophilia A Following Inhibitor Development in NN7170-4213 Trial

Haemophilia A

Austria, Serbia, Bulgaria, United Kingdom, Germany, France, Turkey
Hospital Universitario La Fe

Unknown

Personalized Prophylactic Treatment With Advate® in Severe or Moderate Haemophilia A Patients

Hemophilia A | Factor VIII

Spain
Universidad Católica San Antonio de Murcia

Unknown

Validation of Questionnaires HAL and HEP (VALIDATION)

Haemophilia

Spain
Beijing Children's Hospital

Unknown

Individualized Prophylaxis for Severe Hemophilia A Children

Hemophilia
Columbia University
Grifols Therapeutics LLC

Completed

Intravenous Immunoglobulin (IVIG) in Lung Transplantation

Lung Transplantation | Hypogammaglobulinemia

United States
Assistance Publique - Hôpitaux de Paris

Terminated

Rituximab Plus Corticosteroids in Non-infectious Active Mixed Cryoglobulinemia Vasculitis (ESBAM)

Systemic Vasculitis | Cryoglobulinemia

France
Baylor College of Medicine
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Completed

Study of Antioxidants and Oxidants in Malnourished Children

Kwashiorkor | Marasmus | Protein-energy Malnutrition

Jamaica
BioMarin Pharmaceutical

Recruiting

A Prospective Study Evaluating Seroprevalence and Seroconversion of Antibodies Against Adeno-associated Virus (AAV)

Hemophilia A

Argentina
Institute of Hematology & Blood Diseases Hospital

Not yet recruiting

The Efficacy and Safety of ZS802 in Chinese Hemophilia A Patients.

Hemophilia A

China
University Hospital, Bonn
Swedish Orphan Biovitrum

Recruiting

Sonography and Haemophilia

Haemophilia | Sonography

Germany
BioMarin Pharmaceutical

Active, not recruiting

Phase 3 Study for Efficacy and Safety Outcomes Data in Japanese Patients With Severe Hemophilia A (GENEr8-JPN)

Hemophilia A

Japan
Spark Therapeutics

Completed

A Gene Transfer Study for Hemophilia A

Hemophilia A

United States, Australia, Canada, Israel, Thailand
BioMarin Pharmaceutical

Active, not recruiting

Single-Arm Study To Evaluate The Efficacy and Safety of Valoctocogene Roxaparvovec in Hemophilia A Patients (BMN 270-301) (BMN 270-301)

Hemophilia A

United States, Taiwan, United Kingdom, Australia, Israel, Belgium, Brazil, France, Germany, Italy, Korea, Republic of, South Africa, Spain
Bayer

Completed

BAY81-8973 Pediatric Safety and Efficacy Trial

Haemophilia A

Spain, Russian Federation, United States, Hungary, Italy, Mexico, Norway, Romania, Bulgaria, Canada, Argentina, Denmark, Israel, Poland, Ireland, Latvia, Lithuania
Novo Nordisk A/S

Completed

A Study to Compare the Blood Levels of Mim8 in Healthy Men When Administered With the DV3407-C1 Pen Injector or a Syringe and Cartridge

Haemophilia A

Germany
Baxalta now part of Shire
Takeda Development Center Americas, Inc.; Baxalta Innovations GmbH, now part...

Active, not recruiting

A Study of BAX 888 in Male Adults With Severe Hemophilia A

Hemophilia A

United States, Spain, Hungary, Italy, Germany, Austria, France
Assistance Publique Hopitaux De Marseille

Completed

Determinants and Consequences of the Transition to Adulthood Among Adolescents With Haemophilia (TRANSHEMO)

Haemophilia

France
Bio Products Laboratory

Terminated

Post-Marketing Safety Study Following Long-Term Prophylactic OptivateTreatment in Subjects With Severe Haemophilia A

Haemophilia A

Colombia, Germany, Poland
Hoffmann-La Roche

Completed

A Study to Investigate the Pharmacokinetics, Safety, and Tolerability of Emicizumab in Healthy Chinese Volunteers

Hemophilia A | Healthy Volunteers

China
Bio Products Laboratory

Completed

A Study to Investigate the Safety and Efficacy of Optivate® in Children Under 6 Years of Age With Haemophilia A.

Haemophilia A

Poland
University of Pretoria
Novo Nordisk A/S; Medical Research Council, South Africa

Completed

Combining Registry Data in Haemophilia: TARGET H (TARGET-H)

Haemophilia
Stowarzyszenie Pomocy Chorym na Zakrzepicę i Skazy...

Unknown

Use of a TGA and TEM in the Assessment of the Efficacy of Treatment With APCC or rFVIIa (Thrombus)

Haemophilia

Poland
Bayer

Completed

Validation Study of a cOmputer Pharmacokinetic Tool to assIst in the Follow up Care of haeMophilia A Patients (OPTIMS)

Haemophilia A

France, Italy
Chulalongkorn University

Completed

Comparison of Prophylaxis and On-demand Treatment in Children With Moderate to Severe Hemophilia A

Hemophilia A | Prophylaxis

Thailand
Centers for Disease Control and Prevention

Completed

Joint Outcome Study

Hemophilia A
Swiss Hemophilia Network

Recruiting

Swiss Hemophilia Registry

Hemophilia and Other Severe Bleeding Disorders

Switzerland
Grifols Therapeutics LLC
Instituto Grifols, S.A.

Recruiting

Efficacy and Safety of Fanhdi®, a High-purity Von Willebrand Containing FVIII Concentrate, in Pediatric Patients With Von Willebrand Disease

Von Willebrand Disease

Spain
Bio Products Laboratory

Completed

A Study to Compare the Pharmacokinetics and Safety of Optivate® and Haemate P® in Patients With Von Willebrand Disease.

vonWillebrand's Disease

Israel
Bio Products Laboratory

Terminated

Optivate in People With Von Willebrand Disease Undergoing Surgery

Von Willebrand Disease

Israel, United Kingdom
Bio Products Laboratory

Terminated

A Study With OPTIVATE® in People With Von Willebrand Disease

Von Willebrand Disease

Israel, United Kingdom
Shanghai Belief-Delivery BioMed Co., Ltd
Shanghai MYGT Biopharmaceutical LLC

Recruiting

Evaluation of the Safety and Efficacy of Hemophilia A Gene Therapy Drugs

Hemophilia A

China
East Kent Hospitals University NHS Foundation Trust

Not yet recruiting

Virtual Evaluations of Joint Health Using Wearable Sensors in Persons With Haemophilia (VESPA) (VESPA)

Haemophilia

United Kingdom
BioMarin Pharmaceutical

Enrolling by invitation

A Long-Term Follow-Up Study in Severe Hemophilia A Subjects Who Received BMN 270 in a Prior BioMarin Clinical Trial (270-401) (GENEr8-LTE)

Hemophilia A

United Kingdom, United States
Novo Nordisk A/S

Enrolling by invitation

Adverse Event Data Collection From the EUHASS Registry on Turoctocog Alfa Pegol

Haemophilia A

Denmark
BioMarin Pharmaceutical

Completed

Single-Arm Study To Evaluate The Efficacy and Safety of Valoctocogene Roxaparvovec in Hemophilia A Patients at a Dose of 4E13 vg/kg (GENEr8-2)

Hemophilia A

United States
Hospices Civils de Lyon

Completed

Medication Exposure in Older Patients With Constitutional Hemorrhagic Disease (M-HEMORRH'AGE)

Hemophilia

France
Hospices Civils de Lyon

Unknown

TGA (Thrombin Generation Assay) and Prophylaxis in Haemophilia (HOPE)

Haemophilia A

France
Royal Free Hospital NHS Foundation Trust

Unknown

Inter Individual Variability in Initiation Pathway Activation and Regulation and Phenotypic Heterogeneity in Patients With Haemophilia A and B (InPath)

Haemophilia

United Kingdom
Beijing Children's Hospital

Unknown

Pharmacokinetic (PK)Research on Chinese Children of Hemophilia (PK)

Pharmacokinetics

China
Bio Products Laboratory

Completed

An Open Study to Investigate the Safety and Efficacy of Optivate® in Haemophilia A Patients Undergoing Surgery.

Haemophilia A

Poland, United Kingdom
Bio Products Laboratory

Completed

An Open Study to Investigate the Safety and Efficacy of Optivate® in Severe Haemophilia A Patients.

Haemophilia A

United Kingdom, Poland
Beijing Children's Hospital

Unknown

A Clinical Phenotype Based Individualized Prophylaxis in Chinese Hemophilia A Children (CHIPS)

Haemophilia

China
George A. Kaysen, M.D.
Beth Israel Medical Center

Terminated

The Effect of Thalidomide in Suppression of the Systemic Inflammatory Response Syndrome in Hemodialysis Patients (ICM)

Hypoalbuminemia

United States
Duke University
Grifols Biologicals, LLC

Completed

Anti-thrombin III (ATIII) vs Placebo in Children (<7mo) Undergoing Open Congenital Cardiac Surgery

ATIII Deficiency

United States
Haemnet
UniQure Biopharma B.V.

Completed

An Exploration of the Impact of Gene Therapy on the Lives of People With Haemophilia and Their Families (Exigency)

Hemophilia

United Kingdom
Pfizer

Withdrawn

Patient-reported Outcomes in Subjects Treated With ReFacto AF Routine Prophylaxis

Hemophilia A
Maastricht University Medical Center

Not yet recruiting

Three Channel Food Concept: the Effect Meal Service on Food Intake During Hospitalization

Protein-Energy Malnutrition | Nutrition Poor

Netherlands
University of Saskatchewan
Canadian Blood Services

Recruiting

Treatment of Ligneous Conjunctivitis in Children With Plasminogen Deficiency

Plasminogen Deficiency

Canada

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