Clinical Trials on Brain Pathology

Total 252265 results

Sanofi
Regeneron Pharmaceuticals

Recruiting

Study in Adults With Severe Chronic Rhinosinusitis With Nasal Polyposis Treated With Dupilumab in France (OPALE)

Chronic Rhinosinusitis With Nasal Polyposis

France, Réunion
Hans Bahlmann
Linkoeping University

Recruiting

Spinal Morphine or Intravenous Lidocaine in Robot-assisted Upper Urologic Surgery (SMILe)

Renal Cancer | Ureter Cancer | Other Specified Disorders of Kidney and Ureter | Benign Neoplasm of Ureter | Calculus of Kidney and Ureter | Ureteric Reflux | Congenital Ureteric Anomaly | Benign Renal Neoplasm

Sweden
Foundation For Rare Disease Research
Institute for Asthma & Allergy; Virant Diagnostics, Inc.; MedBio Reference Laboratories...

Not yet recruiting

Angioedema Biomarker Research Study

Angioedema | Urticaria | C1 Inhibitor Deficiency | Angioedemas, Hereditary | Mastocytosis | Indolent Systemic Mastocytosis | Systemic Mastocytoses | ACE Inhibitor-Induced Angioedema
Steno Diabetes Center Copenhagen
King's College London; Juvenile Diabetes Research Foundation; Glostrup University...

Not yet recruiting

Prevention of Chronic Kidney Disease(CDK) Progression in Type 1 Diabetes With Long Term Use of Sodium-Glucose-coTransporter Inhibitors Avoiding Kidney hypOxia (PLUTO)

Hypoxia | Diabetes Mellitus, Type 1 | Diabetic Nephropathies | Albuminuria | Nephropathy | Diabetic Complications Renal | Diabetic Complications Cardiovascular

Denmark
Revolution Medicines, Inc.

Recruiting

Study of RMC-6291 in Combination With RMC-6236 in Participants With Advanced KRAS G12C Mutant Solid Tumors

Colorectal Cancer | Pancreatic Ductal Adenocarcinoma | Non-Small Cell Lung Cancer (NSCLC)

United States, Puerto Rico
InnoCon Medical
Odense University Hospital; Aarhus University Hospital; Herlev Hospital

Recruiting

Safety and Performance of UCon Bar Electrode for the Treatment of Overactive Bladder (OAB) and Bowel Dysfunction (BD)

Urinary Incontinence | Fecal Incontinence | Urinary Incontinence, Urge | Nocturia | Fecal Incontinence With Fecal Urgency | Urinary Frequency More Than Once at Night | Incontinence, Nighttime Urinary | Bowel Disorders Functional

Denmark
Medical College of Wisconsin

Not yet recruiting

LV20.19 CAR T-Cells in Combination With Pirtobrutinib for Relapsed, Refractory B-cell Malignancies

Follicular Lymphoma | Burkitt Lymphoma | Mantle Cell Lymphoma | Marginal Zone Lymphoma | Non Hodgkin Lymphoma | Diffuse Large B Cell Lymphoma
Arizona State University
National Institute on Alcohol Abuse and Alcoholism (NIAAA); San Diego State... and other collaborators

Recruiting

Improving HIV Care Engagement Among Ugandan Adolescent Girls and Young Women: The Kisoboka Mukwano Intervention

Alcohol Use Disorder | Domestic Violence | Intimate Partner Violence | HIV-infection/Aids

Uganda
National Cancer Institute (NCI)

Recruiting

Testing the Combination of Two Anticancer Drugs M1774 (Tuvusertib) and Avelumab to Evaluate Their Safety and Effectiveness in Treating Merkel Cell Skin Cancer, MATRiX Trial

Metastatic Merkel Cell Carcinoma | Refractory Merkel Cell Carcinoma | Locally Advanced Merkel Cell Carcinoma | Unresectable Merkel Cell Carcinoma | Clinical Stage III Cutaneous Merkel Cell Carcinoma AJCC v8 | Clinical Stage IV Cutaneous Merkel Cell Carcinoma AJCC v8

United States
NiKang Therapeutics, Inc.
Pfizer

Recruiting

Ph2 Study NKT2152 With Palbociclib & Sasanlimab in Subjects With Advanced Clear Cell Renal Cell Carcinoma (ccRcc)

Neoplasms | Kidney Cancer | Kidney Neoplasms | Carcinoma, Renal Cell | Urologic Neoplasms | Urogenital Neoplasms | Neoplasms by Site | Kidney Diseases | Urologic Diseases | Adenocarcinoma | Carcinoma | Neoplasms, Glandular and Epithelial | Clear Cell Renal Cell Carcinoma | Metastatic Renal Cell Carcinoma | Recurrent... and other conditions

United States
Jamp Pharma Corporation

Recruiting

The Evaluation of Injection Site Pain and Adherence in Patients Switching From a Low To High Concentration Adalimumab (AVT-02) Across Multiple Indications. (EASE PAIN)

Rheumatoid Arthritis | Plaque Psoriasis | Crohn Disease | Ulcerative Colitis | Hidradenitis Suppurativa | Psoriatic Arthritis | Ankylosing Spondylitis

Canada
University of Aarhus
Department of Clinical Medicine, Aarhus University; Department of Gynaecology... and other collaborators

Recruiting

Improved Diagnosis of Ovarian Cancer

Ovarian Cysts | Ovarian Neoplasms | Ovarian Cancer | Adnexal Mass | Adnexal Lesion | Adnexal Carcinoma | Adnexal Neoplasm

Denmark
University of Minnesota

Recruiting

Natural History Study for DNA Repair Disorders

DNA Repair Disorder | Xeroderma Pigmentosum | Cockayne Syndrome | Trichothiodystrophy

United States
PT Bio Farma
Hasan Sadikin General Hospital

Not yet recruiting

Immunogenicity and Safety of DTP-HB-Hib Using New Hepatitis B Bulk (Bio Farma)

Diphtheria Vaccine Adverse Reaction | Tetanus Vaccine Adverse Reaction | Pertussis Vaccine Adverse Reaction | Haemophilus Influenzae Type B Vaccine Adverse Reaction | Hepatitis B Vaccine Adverse Reaction

Indonesia
Xiaojun Chen

Recruiting

Weight Management Plus Megestrol Acetate in Early-stage Endometrioid Carcinoma

Overweight | Fertility Issues | Obese | Endometrial Carcinoma

China
Bionano Genomics
Columbia University; University of Iowa; Medical College of Wisconsin; Augusta... and other collaborators

Recruiting

Validation of Optical Genome Mapping for the Identification of Constitutional Genomic Variants in a Postnatal Cohort

Intellectual Disability | Autism Spectrum Disorder | Fragile X Syndrome | Developmental Disability | Congenital Anomaly | Facioscapulohumeral Muscular Dystrophy 1

United States
University of Namibia
European and Developing Countries Clinical Trials Partnership (EDCTP); Research... and other collaborators

Recruiting

Collision of Three Global Pandemics: the Effect of Tuberculosis and HIV on the Epidemiological, Clinical, Virological and Immunological Trajectory of COVID-19 in Botswana and Namibia (Core-NB)

COVID-19 | HIV Seropositivity | Tuberculosis, Pulmonary | Tuberculosis Infection

Namibia
West China Hospital

Recruiting

Computer Aided Diagnostic Tool on Computed Tomography Images for Diagnosis of Retroperitoneal Tumor in Children

Sarcoma | Lymphoma | Neuroblastoma | Wilms' Tumor | Teratoma | Germ Cell Tumor

China
Assistance Publique - Hôpitaux de Paris

Recruiting

Impact of COVID-19 SARS-CoV-2 Variability in ICU Hospitalized Patients With Severe Disease (SEVARVIR)

SARS-CoV2 Infection | Mutation | COVID-19 Acute Respiratory Distress Syndrome

France
NUMEN Foundation
Hospital de Emergencias Enfermera Isabel Zendal de Madrid

Not yet recruiting

Effect of Vojta Therapy on Covid-19 Respiratory Disease

COVID-19 Acute Respiratory Distress Syndrome
Dwight Owen
Genentech, Inc.

Recruiting

Temozolomide and Atezolizumab as Second or Third Line for the Treatment of Metastatic or Recurrent Small Cell Lung Cancer

Stage IVA Lung Cancer AJCC v8 | Stage IVB Lung Cancer AJCC v8 | Stage IV Lung Cancer AJCC v8 | Extensive Stage Lung Small Cell Carcinoma | Metastatic Lung Small Cell Carcinoma | Recurrent Lung Small Cell Carcinoma

United States
Assistance Publique - Hôpitaux de Paris

Not yet recruiting

Study of Leukocyte Populations in Patients With Chronic Inflammatory (LIMA)

Rheumatoid Arthritis | Systemic Lupus Erythematosus | Sjogren's Syndrome | Spondyloarthritis | Chronic Inflammatory Rheumatism | Systemic Autoimmune Disease

France
University of Rochester

Recruiting

Curcumin and Piperine in Patients on Surveillance for Monoclonal Gammopathy, Smoldering Myeloma or Prostate Cancer

Multiple Myeloma | Prostate Cancer | Monoclonal Gammopathy of Undetermined Significance | Smoldering Multiple Myeloma (SMM)

United States
ARCAGY/ GINECO GROUP
Merck Sharp & Dohme LLC; OSE Immunotherapeutics

Recruiting

OSE2101 Alone or in Combination With Pembrolizumab vs BSC in Patient With Platinum-sensitive Recurrent OC (TEDOVA)

Relapsed Ovarian Cancer | Platinum-sensitive Ovarian Cancer

Belgium, France, Germany
Novartis Pharmaceuticals

Recruiting

Study of JDQ443 in Patients With Advanced Solid Tumors Harboring the KRAS G12C Mutation (KontRASt-01)

Carcinoma, Non-Small-Cell Lung | Lung Cancer | Neoplasms, Lung | Pulmonary Neoplasms | Neoplasms, Pulmonary | Pulmonary Cancer | Cancer of Lung | Cancer of the Lung | KRAS G12C Mutant Solid Tumors | Carcinoma, Colorectal

United States, Japan, Australia, Germany, Italy, Spain, Canada, Denmark, Korea, Republic of, Taiwan, Belgium, Hong Kong, China, France, Singapore, Netherlands
Academisch Medisch Centrum - Universiteit van Amsterdam...
IRCCS Azienda Ospedaliero-Universitaria di Bologna; Hospital Clinic of Barcelona and other collaborators

Recruiting

A Personalized Surveillance and Intervention Protocol for Duodenal and Gastric Polyposis in Patients With Familial Adenomatous Polyposis

Familial Adenomatous Polyposis

Netherlands
Medical University Innsbruck

Recruiting

Prospective Registry of Eosinophilia With Respiratory Manifestations With Translational Research Identifying and Characterizing Eosinophils (PROMETHEos)

Eosinophilic Asthma | Eosinophilic Pneumonia | EGPA - Eosinophilic Granulomatosis With Polyangiitis | Samter Triad | HES - Hypereosinophilic Syndrome

Austria
CAI Hongbing

Recruiting

A Randomized Prospective Trail of HIPEC in Recurrent Ovarian Cancer Patients With HRR Mutation

Ovarian Cancer | Epithelial Ovarian Cancer | Ovarian Cancer, Epithelial | Hyperthermic Intraperitoneal Chemotherapy(HIPEC) | Homologous Recombination Repair Gene Mutation

China
National Cancer Institute (NCI)

Recruiting

EA2176: Phase 3 Clinical Trial of Carboplatin and Paclitaxel +/- Nivolumab in Metastatic Anal Cancer Patients

Anal Canal Cloacogenic Carcinoma | Metastatic Anal Squamous Cell Carcinoma | Recurrent Anal Squamous Cell Carcinoma | Stage III Anal Cancer AJCC v8 | Stage IV Anal Cancer AJCC v8 | Unresectable Anal Squamous Cell Carcinoma | Anal Basaloid Squamous Cell Carcinoma

United States
Children's Oncology Group
National Cancer Institute (NCI)

Recruiting

A Study of Combination Chemotherapy for Patients With Newly Diagnosed DAWT and Relapsed FHWT

Stage II Kidney Wilms Tumor | Stage III Kidney Wilms Tumor | Stage IV Kidney Wilms Tumor | Recurrent Kidney Wilms Tumor | Anaplastic Kidney Wilms Tumor

United States, Canada, Puerto Rico, Australia, New Zealand, Saudi Arabia
Mayo Clinic
National Cancer Institute (NCI)

Recruiting

WSD0922-FU for the Treatment of Glioblastoma, Anaplastic Astrocytoma, or Non-small Cell Lung Cancer With Central Nervous System Metastases

Metastatic Lung Non-Small Cell Carcinoma | Anaplastic Astrocytoma, IDH-Wildtype | Glioblastoma, IDH-Wildtype | Metastatic Malignant Neoplasm in the Central Nervous System

United States
National Cancer Institute (NCI)

Recruiting

Osimertinib With or Without Bevacizumab as Initial Treatment for Patients With EGFR-Mutant Lung Cancer

Stage IV Lung Cancer AJCC v8 | Stage IIIB Lung Cancer AJCC v8 | Advanced Lung Non-Squamous Non-Small Cell Carcinoma | Metastatic Lung Non-Squamous Non-Small Cell Carcinoma | Recurrent Lung Non-Squamous Non-Small Cell Carcinoma

United States
National Cancer Institute (NCI)

Recruiting

A Study of the Drugs Selumetinib Versus Carboplatin/Vincristine in Patients With Neurofibromatosis and Low-Grade Glioma

Neurofibromatosis Type 1 | Low Grade Glioma | Visual Pathway Glioma

United States, Canada, Puerto Rico
Gruppo Italiano Malattie EMatologiche dell'Adulto

Recruiting

The Incidence of Hepatitis B in Diffuse Large B-Cell Lymphoma/Chronic Lymphoid Leukemia HBsAg-positive Treated With Rituximab, Chemotherapy and Tenofovir Alafenamide (CLL1818)

Chronic Lymphoid Leukemia | Large-B-cell Diffuse Lymphoma

Italy
Children's Hospital of Philadelphia

Recruiting

Unrelated And Partially Matched Related Donor PSCT w/ T Cell Receptor (TCR) αβ Depletion for Patients With BMF

Paroxysmal Nocturnal Hemoglobinuria | Acquired Aplastic Anemia | Inherited Bone Marrow Failure Syndromes

United States
University of Rochester

Recruiting

Umbilical Cord Blood Transplantation From Unrelated Donors

Lymphoma | Myelodysplastic Syndromes | Multiple Myeloma | Solid Tumor | Acute Leukemia | Aplastic Anemia | Chronic Leukemia | Immune Deficiency Disorder | Congenital Hematological Disorder | Metabolism Disorder

United States
New York Medical College
Roswell Park Cancer Institute

Recruiting

Obinutuzumab and ICE Chemotherapy in Refractory/Recurrent CD20+ Mature NHL (O-ICE)

Diffuse Large B-Cell Lymphoma | Burkitt Lymphoma | Non-Hodgkin Lymphoma | Primary Mediastinal B-cell Lymphoma | CD20+ Lymphoblastic Lymphoma | Follicular Lymphoma, Grade III

United States
Oslo University Hospital
The Research Council of Norway

Recruiting

Peritoneal Surface Malignancies - Characterization, Models and Treatment Strategies (PSM)

Mesothelioma | Pseudomyxoma Peritonei | Colorectal Carcinoma | Ovarian Carcinoma

Norway
Mayo Clinic
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); National... and other collaborators

Recruiting

Rare Kidney Stone Consortium Patient Registry (RKSC)

Cystinuria | Primary Hyperoxaluria | Dent Disease | APRT Deficiency

United States, Iceland
National Cancer Institute (NCI)

Recruiting

Evaluation of Cell Changes in Blood and Tissue in Cancers of the Lung, Esophagus and Lung Lining

Malignant Pleural Mesotheliomas NOS | Esophageal Cancers NOS | Lung Cancer NOS | Thoracic Cancers | Cancers of Non Thoracic Origin With Metastases to the Lungs or Pleura

United States
National Cancer Institute (NCI)

Active, not recruiting

Testing the Addition of an Antibody to Standard Chemoradiation Followed by the Antibody for One Year to Standard Chemoradiation Followed by One Year of the Antibody in Patients With Unresectable Stage III Non-Small Cell Lung Cancer

Stage III Lung Cancer AJCC v8 | Stage IIIA Lung Cancer AJCC v8 | Stage IIIB Lung Cancer AJCC v8 | Stage IIIC Lung Cancer AJCC v8 | Unresectable Lung Non-Small Cell Carcinoma | Recurrent Lung Non-Small Cell Carcinoma

United States, Guam
National Cancer Institute (NCI)

Active, not recruiting

Combination Chemotherapy With or Without Donor Stem Cell Transplant in Treating Patients With Acute Lymphoblastic Leukemia

Acute Lymphoblastic Leukemia | Recurrent Adult Acute Lymphoblastic Leukemia | Adult B Acute Lymphoblastic Leukemia | Adult T Acute Lymphoblastic Leukemia | Adult B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1 | Adult L1 Acute Lymphoblastic Leukemia | Adult L2 Acute Lymphoblastic...

United States
Jose Soberon, MD

Terminated

Exparel as a Nerve Block for Severe Hand Pain

Scleroderma, Diffuse | Peripheral Vascular Disease | Raynaud Disease | CREST Syndrome

United States
Regeneron Pharmaceuticals
Sanofi

Active, not recruiting

Study Assessing Long-teRm Outcomes of dupiluMAb (DUPIXENT®) Treatment in Adult Patients With Chronic Rhinosinusitis With Nasal Polyposis (CRSwNP) (AROMA)

Chronic Rhinosinusitis With Nasal Polyposis

United States, Italy, Canada, Japan, Germany, Netherlands
University of California, Los Angeles
Oregon Health and Science University

Completed

Androgen Excess as a Cause for Adipogenic Dysfunction in PCOS Women

Polycystic Ovary Syndrome (PCOS)

United States
Wroclaw Medical University

Enrolling by invitation

Selected Disorders and Sleep Bruxism

Cardiovascular Diseases | Hypertension | Sleep Apnea | Cardiovascular Risk Factor | Sleep Disorders | Temporomandibular Disorder | Sleep Bruxism | Thyroid Dysfunction | Mental Status Change

Poland
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Anamorelin Hydrochloride in Reducing Anorexia in Patients With Advanced Non-small Cell Lung Cancer

Anorexia | Stage IVA Lung Cancer AJCC v8 | Stage IVB Lung Cancer AJCC v8 | Lung Non-Small Cell Carcinoma | Stage III Lung Cancer AJCC v8 | Stage IV Lung Cancer AJCC v8 | Stage IIIA Lung Cancer AJCC v8 | Stage IIIB Lung Cancer AJCC v8 | Stage IIIC Lung Cancer AJCC v8

United States
David Bushnell
National Cancer Institute (NCI); Holden Comprehensive Cancer Center; Perspective...

Active, not recruiting

A Safety Study of 212Pb-VMT-alpha-NET in Patients With Neuroendocrine Tumors

Neuroendocrine Tumors | Neuroendocrine Tumor of the Lung | Neuroendocrine Tumor Grade 2 | Neuroendocrine Tumor Grade 1 | Neuroendocrine Tumor of Pancreas

United States
S.L.A. Pharma AG

Active, not recruiting

Effect of EPA-FFA on Polypectomy in Familial Adenomatous Polyposis

Familial Adenomatous Polyposis

Italy
Benha University

Completed

Impact Of Maternal Spinal Anesthesia-Induced Hypotension At Scheduled Cesarean Delivery On Risk Development Of Transient Tachypnea Of Newborn And Fetal Acidosis

Transient Tachypnea of Newborn and Fetal Acidosis

Egypt

Clinical Trials on Brain Pathology

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Medical Conditions

Drug Interventions

CROs by country

CROs in Oman

Conditions

Rare Diseases

Drug Interventions

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