Clinical Trials on Breakthrough Infections

Total 56763 results

King Saud University

Unknown

A Retrospective Epidemiological Study on Pneumococcal Infection in Children in Ministry of Health Hospital at EHSA Region in the Eastern Province (IPD in saudi)

Pneumococcal Infection
Hospital Universitario de Valme

Recruiting

Natural History of Clostridioides Difficile Infection

Clostridium Difficile Infection | Nosocomial Infection | Health Care Associated Infection

Spain
AO Clinical Investigation and Publishing Documentation

Completed

Clinical Priority Program-Bone Infection Registry (CPPInfection)

Staphylococcus Aureus | Bone Infection

United States, Belgium, Denmark, China, Argentina, Germany, Japan, Switzerland, Austria, Canada
Enanta Pharmaceuticals, Inc
hVIVO Services Limited

Recruiting

A Controlled Phase 2a Study to Evaluate the Efficacy of EDP-323 Against Respiratory Syncytial Virus Infection in a Virus Challenge Model

RSV Infection

United Kingdom
Jun Zhang
Liuzhou center of disease prevention and control

Completed

The Epidemiologic Study of Human Papillomavirus Infection and Related Diseases

Human Papillomavirus Infection | Genital Warts

China
Serum Institute of India Pvt. Ltd.
Vakzine Projekt Management GmbH

Active, not recruiting

Evaluation of Efficacy and Safety of VPM1002 in Comparison to BCG in Prevention of Tb Infection in Infants (VPM1002)

Mycobacterium Tuberculosis Infection

Gabon, Kenya, South Africa, Tanzania, Uganda
Limited Liability Company Pharm Aid

Completed

Reactogenicity, Safety and Immunological Efficacy of the Live, Pentavalent Rotavirus Vaccine in Childhood Immunization

Rotavirus Infection

Russian Federation
Pfizer

Completed

Complicated Skin and Skin Structure Infections

Abscess | Cellulitis | Skin Infection
The University of Hong Kong
Hospital Authority, Hong Kong

Completed

Lopinavir/ Ritonavir, Ribavirin and IFN-beta Combination for nCoV Treatment

Novel Coronavirus Infection

Hong Kong
Seoul National University Bundang Hospital

Recruiting

The Efficacy of the 7 Days Tailored Therapy as the 1st Eradication of H. Pylori Infection

Helicobacter Infection

Korea, Republic of
Seoul National University Bundang Hospital

Terminated

The Efficacy of the 7 Days Tailored Therapy as 2nd Rescue Therapy for Eradication of H. Pylori Infection

Helicobacter Infection

Korea, Republic of
Institute of Progressive Medicine

Completed

Activation of Alternative Cellular Energy (ACE) Pathway in the Therapy of Herpes Virus Infections

Herpes Zoster | Herpes Simplex
TD Vaccines A/S
Johns Hopkins University; University of Vermont; SNBL Clinical Pharmacology Center... and other collaborators

Unknown

ACE393-103 Vaccination Challenge Study (ACE393-103VC)

Campylobacter Infection

United States
Gifu Prefecture Medical Association
Sanofi Pasteur S.A.

Completed

Seroepidemiological Study of Pertussis and Other Infectious Diseases

Pertussis Infection

Japan
University of Bern
University of Alabama at Birmingham; University of Southern California; Louisiana... and other collaborators

Active, not recruiting

Genital Tract Infections, the Vaginal Microbiome and Gestational Age at Birth Among Pregnant Women in South Africa

HIV Infections | Premature Birth | Microbial Colonization | Pregnancy; Infection | Bacterial Vaginosis | Trichomonas Vaginitis | Neisseria Gonorrheae Infection | Chlamydia Trachomatis Infection | Mycoplasma Genitalium Infection | Genital Mycoplasma Infection | Vaginal Candida | Sexually Transmitted Infections... and other conditions

South Africa
Denver Health and Hospital Authority
Washington University School of Medicine; Vanderbilt University Medical Center and other collaborators

Not yet recruiting

RELAX: Reducing Length of Antibiotics for Children With Ear Infections (RELAX)

Pediatric Infectious Disease | Acute Otitis Media | Ear Infection
Denver Health and Hospital Authority
Patient-Centered Outcomes Research Institute; Mayo Clinic; Intermountain Health... and other collaborators

Not yet recruiting

Interventions to De-implement Unnecessary Antibiotic Prescribing for Children With Ear Infections (DISAPEAR)

Pediatric Infectious Disease | Acute Otitis Media | Ear Infection
Hospital Moinhos de Vento

Terminated

Seven Versus 14 Days of Antibiotic Therapy for Multidrug-resistant Gram-negative Bacilli Infections (OPTIMISE)

Sepsis | Gram-Negative Bacterial Infections | Bacteremia | Severe Infection | Bloodstream Infection | Acinetobacter Infections | Pseudomonas Aeruginosa | Human | Carbapenem-Resistant Enterobacteriaceae Infection | Carbapenem Resistant Bacterial Infection

Brazil
Hospital for Special Surgery, New York
Children's Healthcare of Atlanta; Campbell Clinic; Pediatric Orthopaedic Society... and other collaborators

Recruiting

Alpha-Defensin and Synovial Proteins to Improve Detection of Pediatric Septic Arthritis

Septic Arthritis | Joint Infection | Infection of Hip Joint (Disorder) | Infection of Shoulder Joint

United States
Assistance Publique Hopitaux De Marseille

Unknown

Therapeutic Drug Monitoring of Anti-infectious Drugs in Intensive Care Unit (STP-ATB-REA)

Infection, Bacterial
Imperial College London

Recruiting

The Impact of Age on Adaptive Immunity in Adults Infected With Respiratory Syncytial Virus (INFLAMMAGE)

RSV Infection

United Kingdom
Bavarian Nordic

Completed

Phase 2a Study of MVA-BN-RSV Vaccination and RSV Challenge in Healthy Adults

RSV Infection

United Kingdom
Meissa Vaccines, Inc.
Hvivo

Completed

Human Challenge Study to Evaluate the Efficacy of MV-012-968 Vaccine

RSV Infection

United Kingdom
Ark Biosciences Inc.

Unknown

Anti-RSV Study in Chinese Patients (ASCENT) (ASCENT)

Respiratory Syncytial Virus Infections

China
Alios Biopharma Inc.

Completed

A Phase 2a Study to Evaluate ALS-008176 in the Virus Challenge Model

Respiratory Syncytial Virus Infections

United Kingdom
G.V. (Sonny) Montgomery VA Medical Center

Unknown

Herpes Simplex Type 2 Co-infection in Veterans With Chronic Hepatitis C

Hepatitis C Virus Infection | Infection | Herpesvirus 2, Human

United States
University of Duhok

Not yet recruiting

Parenteral Versus Combined Parenteral With Vancomycin-soaked Graft in ACL Reconstruction

Infection, Bacterial
Columbia University

Withdrawn

Procalcitonin Guided Antibiotic Therapy

Intra-Abdominal Infections
Melinta Therapeutics, Inc.
Department of Health and Human Services

Completed

Pharmacokinetics and Safety of Solithromycin in Adolescents and Children

Bacterial Infection

United States, Bulgaria
Shanghai Ark Biopharmaceutical Co., Ltd.
Shanghai Ark Biopharmaceutical Co., Ltd.

Completed

A Study of AK0529 in Chinese Infants Hospitalized With RSV (AIRFLO)

Respiratory Syncytial Virus Infections

China
Enanta Pharmaceuticals, Inc
hVIVO Services Limited

Completed

A Phase 2a Study to Evaluate EDP-938 in the Virus Challenge Model

RSV Infection

United Kingdom
Hvivo
GlaxoSmithKline

Completed

RSV Study in Adults 60 to 75 Years of Age

RSV Infection

United Kingdom
Seoul National University Hospital

Unknown

One Sequencing Find All for Helicobacter Pylori Infection

Helicobacter Pylori Infection | Resistant Infection

Korea, Republic of
Cancer Institute and Hospital, Chinese Academy...
Henan Provincal Center for Disease Control and Prevention

Unknown

Safety and Preliminary Immunogenicity Study of Inactivated Vaccine for Prevention of Rotavirus Infection

Rotavirus Infection

China
Prof. Dr. Ulrich Heininger
Luzerner Kantonsspital

Completed

Long- and Midterm Outcomes of Osteoarticular Infections in Paediatric Patients (LOOP)

Septic Arthritis | Acute Haematogenous Osteomyelitis

Switzerland
Merck Sharp & Dohme LLC

Completed

Safety, Efficacy, and Pharmacokinetics (PK) of Daptomycin (MK-3009) in Japanese Pediatric Subjects With Complicated Skin and Soft Tissue Infections (cSSTI) and Bacteremia (MK-3009-029)

Skin Diseases, Infectious | Bacteremia | Soft Tissue Infections

Japan
Allergan

Completed

Development of a New Critical Pathway for Treatment of Acute Bacterial Skin and Skin Structure Infections (ABSSSI)

Bacterial Infections | Acute Bacterial Skin and Skin Structure Infection

United States
National Institute of Allergy and Infectious Diseases...

Completed

The Effect of Acyclovir Treatment of the Herpes Simplex Virus (HSV) Infection on HIV Levels in the Blood

HIV Infections | Herpes Simplex

United States
Prof. Tobias Feuchtinger
European Commission; Simbec-Orion Group Ltd, Merthyr Tydfil, UK; Miltenyi Biotec... and other collaborators

Recruiting

Multivirus-specific T-cell Transfer Post SCT vs AdV, CMV and EBV Infections (TRACE)

CMV Infection | EBV Infection | Stem Cell Transplant Complications | AdV Infection

Belgium, Spain, France, Germany, Italy, Netherlands
TenNor Therapeutics (Suzhou) Limited

Completed

Efficacy and Safety of Rifasutenizol (TNP 2198) in Participants With H. Pylori Infection

H.Pylori Infection

China
University of Heidelberg Medical Center
University of Sao Paulo

Withdrawn

ZIKAlliance Natural History Study (ZIKAllianceNH)

Zika Virus Infection | Zika Virus

Brazil
Ascension South East Michigan

Completed

The Use of Medical Grade Honey in the Prevention of Bone Anchored Hearing Aid Associated Skin Breakdown

Skin Infection

United States
University of North Carolina, Chapel Hill
National Institute of Allergy and Infectious Diseases (NIAID)

Enrolling by invitation

Community-associated Highly-Resistant Enterobacterales (COCARE)

Enterobacteriaceae Infections | Community-Acquired Infections | Healthcare Associated Infection | Carbapenem-Resistant Enterobacteriaceae Infection

United States
Assistance Publique - Hôpitaux de Paris
Institut Pasteur

Completed

Monoclonal Antibodies in Clostridium Difficile Infection (IgAClostridium)

Clostridium Infection

France
The University of Texas Health Science Center at...
Pfizer

Completed

Effectiveness of Rifabutin in the Treatment of Mycobacterium Avium Complex

Nontuberculous Mycobacterial Infections

United States
AGUNCO Obstetrics and Gynecology Centre

Completed

Polyhexamethylene Biguanide Increases the Regression Rate of Human Papillomavirus (HPV) Infection

HPV Infection

Italy
Qilu Hospital of Shandong University

Not yet recruiting

Efficacy and Safety of Bismuth Quadruple Therapy Containing Cefuroxime and Tetracycline as First-line Therapy for Eradicating Helicobacter Pylori in Patients Allergic to Penicillin

Helicobacter Pylori Infection

China
University Medical Centre Ljubljana

Recruiting

Bismuth Quadruple Therapy Versus Standard Triple Therapy (BismoHelP)

Helicobacter Pylori Infection

Slovenia
Chinese University of Hong Kong

Active, not recruiting

FMT for Moderate to Severe CDI: A Randomised Study With Concurrent Stool Microbiota Assessment

Clostridium Difficile Infection

Hong Kong
Shanghai East Hospital

Suspended

Bismuth Quadruple Therapy With Cefuroxime for Helicobacter Pylori Eradication Treatment

Helicobacter Pylori Infection

China

Clinical Trials on Breakthrough Infections

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Taiwan

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Rare Diseases

Drug Interventions

Dietary Supplements

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