Clinical Trials on Breast Tumor

Total 30308 results

Filipa Lynce, MD
Merck Sharp & Dohme LLC; Zentalis Pharmaceuticals

Not yet recruiting

A Phase I/II Single-arm Trial of Azenosertib (ZN-c3) Combined With Carboplatin and Pembrolizumab in Patients With Metastatic Triple-negative Breast Cancer (ZAP-IT)

Breast Cancer | Triple Negative Breast Cancer | Breast Cancer Female | HER2-negative Breast Cancer | Hormone Receptor Negative Malignant Tumor Breast Triple

United States
Kathy Miller
Pfizer; Astex Pharmaceuticals, Inc.; Van Andel Institute Stand Up to Cancer Team

Completed

Study of ASTX727 Plus Talazoparib in Patients With Triple Negative or Hormone Resistant/HER2-negative Metastatic Breast Cancer

Metastatic Breast Cancer | Triple Negative Breast Cancer | Hormone Receptor Positive Tumor

United States
Jules Bordet Institute

Recruiting

Multidisciplinary Approach to Fatigue

Breast Cancer | Germ Cell Tumor

Belgium
RenJi Hospital
Beijing Viroad Biotechnology Co., Ltd.

Completed

CTC in Predicting Neoadjuvant Chemotherapy Among LABC Patients: a Single-center, Prospective, Exploratory Clinical Trial (CTCNeoBC)

Locally Advanced Breast Cancer | Circulating Tumor Cell

China
St Vincent's Hospital

Recruiting

A Window of Opportunity Study of Pre-operative Endocrine Therapy With and Without Prometrium in Postmenopausal Women With Early Stage Breast Hormone Receptor Positive (HR+) Human Epidermal Receptor 2 Negative (HER2-) Breast Cancer. (WinPro)

Hormone Receptor Positive Tumor | Early-stage Breast Cancer

Australia
Thomas Hatschek

Active, not recruiting

Neoadjuvant Response-guided Treatment of Slowly Proliferating Hormone Receptor Positive Tumors (PREDIX LumA)

Early-Stage Breast Carcinoma | Hormone Receptor Positive Tumor

Sweden
Eli Lilly and Company

Completed

A Neoadjuvant Study of Abemaciclib (LY2835219) in Postmenopausal Women With Hormone Receptor Positive, HER2 Negative Breast Cancer (neoMONARCH)

Breast Cancer | Early-Stage Breast Carcinoma | Hormone Receptor Positive Tumor

United States, Canada, Korea, Republic of, Italy, Austria, Belgium, Germany, Netherlands, Spain, Taiwan
NSABP Foundation Inc
Royal Marsden NHS Foundation Trust; Pfizer; Institute of Cancer Research, United...

Completed

A Phase II Randomized Study Evaluating the Biological and Clinical Effects of the Combination of Palbociclib With Letrozole as Neoadjuvant Therapy in Post-Menopausal Women With Estrogen-Receptor Positive Primary Breast Cancer (PALLET)

Breast Cancer | Breast Tumors | Breast Carcinoma

United Kingdom, United States, Canada
Novartis Pharmaceuticals

Completed

Yttrium Y 90 SMT 487 in Treating Patients With Refractory or Recurrent Cancer

Lymphoma | Breast Cancer | Lung Cancer | Brain and Central Nervous System Tumors | Melanoma (Skin) | Islet Cell Tumor | Gastrointestinal Carcinoid Tumor | Neoplastic Syndrome

United States
Assistance Publique - Hôpitaux de Paris
Ligue contre le cancer, France; Imagine Institute

Not yet recruiting

Contribution of 3D Modeling in Surgical Management of Pediatric Retroperitoneal and Pelvic Tumors (3D-PEDSURG)

Pelvic Tumor | Retroperitoneal Tumor

France
Hospital Universitari de Bellvitge

Recruiting

Impact of Systematic Shaving on Margins

Breast Cancer | Surgery | Margin, Tumor-Free

Spain
Oslo University Hospital
Norwegian Cancer Society; Klinbeforsk

Active, not recruiting

Establishment of Molecular Profiling for Individual Clinical Routine Treatment Decision in Early Breast Cancer (EMIT)

Breast Cancer | Breast Neoplasms | Hormone Receptor Positive Tumor

Norway
Hospital Universitario San Ignacio
Pontificia Universidad Javeriana

Recruiting

Safety and Efficacy Evaluation of the P2Et Extract in Patients With Breast Cancer

Quality of Life | Breast Cancer | Tumor, Breast

Colombia
Laekna Limited

Completed

PhI to Solid Tumors and PhII to Locally Advanced or mTNBC

Solid Tumor | TNBC - Triple-Negative Breast Cancer

China
NYU Langone Health

Completed

Phase II Study for Solid Metastatic Tumors

Breast Cancer | Solid Tumor | Metastatic Breast Cancer
Pfizer

Completed

A Study to Describe the Breast Cancer Patient Population, Treatment, and Results in Indian Patients Receiving Combinations of the Medicines Called Palbociclib for Advanced Breast Cancer

Breast Cancer | Breast Neoplasms | Breast Tumors | Breast Carcinoma | Cancer of Breast

India
Georgetown University
Immune System Key Ltd

Recruiting

NEROFE and Doxorubicin in KRAS-mutated ST2-positive Solid Tumors

Solid Tumor | KRAS Mutation-Related Tumors

United States
Case Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

PET/CT or PET/MRI in Measuring Tumors in Patients Undergoing Clinical Imaging or With Newly Diagnosed Breast Cancer

Breast Cancer | Unspecified Adult Solid Tumor, Protocol Specific

United States
National Institutes of Health Clinical Center (CC)
National Cancer Institute (NCI)

Completed

Effects of Fetal, Infant, and Early Childhood Exposures on Adult Cancer Risk in Women

Breast Cancer | Unspecified Adult Solid Tumor, Protocol Specific

United States
Columbia University

Completed

Pre-Surgical Trial of the Combination of Metformin and Atorvastatin in Newly Diagnosed Operable Breast Cancer

Breast Cancer | Breast Tumors | Cancer of Breast

United States
Pamela Munster
QuantumLeap Healthcare Collaborative

Terminated

Study of BMN-673 With Carboplatin and Paclitaxel in Patients With Advanced BRCA-mutated Solid Tumor or Triple Negative Metastatic Breast Cancer

Triple Negative Metastatic Breast Cancer | BRCA-mutated Solid Tumor

United States
Mayo Clinic
National Cancer Institute (NCI)

Completed

Flavopiridol Plus Cisplatin or Carboplatin in Treating Patients With Advanced Solid Tumors

Breast Cancer | Prostate Cancer | Unspecified Adult Solid Tumor, Protocol Specific | Melanoma (Skin)

United States
Samsung Medical Center

Recruiting

Impact of Immuno-Oncologic Agent on Neoadjuvant Chemotherapy in Triple Negative Breast Cancer

Triple Negative Breast Cancer | Pembrolizumab | Neoadjuvant Chemotherapy | Tumor Microenvironment

Korea, Republic of
XU Zhi
Peking University

Unknown

Detection of Benign and Malignant Thyroid and Breast Tumors by Fourier Transform Infrared Spectrometry

Breast Tumor | Thyroid Tumor

China
Peking Union Medical College Hospital

Not yet recruiting

Pyrotinib Combined With Trastuzumab and AI in the First-line Treatment of HER2 Positive/ HR Positive MBC (Pyrotinib)

Breast Diseases | Metastatic Breast Cancer | HER2-positive Breast Cancer | Hormone Receptor Positive Malignant Neoplasm of Breast | Breast Cancer Female | Hormone Receptor Positive Tumor
Innervate Radiopharmaceuticals LLC (Formerly: Illumina...
Albert Einstein College of Medicine

Not yet recruiting

18F-mFBG Expression in Neural Crest Tumors and Organs Innervated by the Sympathetic Nervous System

Neuroblastoma | Pheochromocytoma | Paraganglioma

United States
University of Michigan

Completed

Digital Mammography: Computer-Aided Breast Cancer Diagnosis

Tumors, Breast

United States
Gustave Roussy, Cancer Campus, Grand Paris

Completed

Treatment of High-Risk Cerebral Primitive Neuroectodermal Tumors in Children Aged Over 5 Years

Metastatic, Cerebral Primitive Neuroectodermal Tumors

France
University of Saskatchewan

Active, not recruiting

Role of Individualized Intervention(s) in Hormone-Receptor Positive Early-stage Breast Cancer (MyCHOICE)

Breast Cancer | Hormone Receptor Positive Tumor | Premenopausal Breast Cancer

Canada
National Cancer Institute (NCI)

Completed

Decitabine in Treating Patients With Advanced Solid Tumors

Unspecified Adult Solid Tumor, Protocol Specific | Recurrent Melanoma | Recurrent Bladder Cancer | Stage IV Bladder Cancer | Male Breast Cancer | Stage IV Breast Cancer | Stage IV Melanoma | Recurrent Breast Cancer | Stage III Melanoma

United States
NantCell, Inc.

Completed

QUILT-3.025: A Phase 2 Study of AMG 479 in Relapsed or Refractory Ewing's Family Tumor and Desmoplastic Small Round Cell Tumors

Sarcoma | Ewing's Sarcoma | Primitive Neuroectodermal Tumors (PNETs) | Askin's Tumors | Desmoplastic Small Round Cell Tumors | Estraosseous Ewing's Tumor | Ewing's Family Tumor
University of Southern California
National Cancer Institute (NCI)

Recruiting

A Dose Finding Phase 1 of Sarilumab Plus Capecitabine in HER2/Neu-Negative Metastatic Breast Cancer and a Single-arm, Historically-controlled Phase 2 Study of Sarilumab Plus Capecitabine in Stage I-III Triple Negative Breast Cancer With High-Risk Residual Disease (EMPOWER) (EMPOWER)

Cancer | Metastatic | Breast | Triple Negative | Disseminated Tumor Cell

United States
Hebei Medical University Fourth Hospital

Not yet recruiting

Olaparib in the Treatment of BRCA1/2 Unmutated and BRCA1 Promoter Methylated Recurrent and Metastatic Triple-negative Breast Cancer

Solid Tumor
Sichuan Baili Pharmaceutical Co., Ltd.
SystImmune Inc.; Baili-Bio (Chengdu) Pharmaceutical Co., Ltd.

Recruiting

A Study of BL-M07D1 in Patients With Locally Advanced or Metastatic HER2 Positive/Low Expression Breast Cancer and Other Solid Tumors

Breast Cancer | Locally Advanced or Metastatic Solid Tumor

China
Spectrum Pharmaceuticals, Inc

Terminated

A Study of Poziotinib in Patients With Epidermal Growth Factor Receptor (EGFR) or Human Epidermal Growth Factor Receptor 2 (HER2) Activating Mutations in Advanced Malignancies

Breast Cancer | Colorectal Cancer | Solid Tumor | Glioblastome Multiforme

United States
Fuzhou General Hospital

Not yet recruiting

Pyrotinib Combined With Trastuzumab Plus Aromatase Inhibitor in Treatment of Breast Cancer

Breast Diseases | Metastatic Breast Cancer | HER2-positive Breast Cancer | Hormone Receptor Positive Malignant Neoplasm of Breast | Breast Cancer Female | Hormone Receptor Positive Tumor

China
MedSIR
Pfizer

Completed

PALbociclib Rechallenge in horMone Receptor-posItive/HER2- Negative Advanced Breast Cancer (PALMIRA) (PALMIRA)

Breast Cancer | Advanced Breast Cancer | Hormone Receptor Positive Tumor | Human Epidermal Growth Factor 2 Negative Carcinoma of Breast

Spain, Germany, France, United Kingdom, Italy, Slovenia
GE Healthcare

Terminated

Assessment of Diagnostic Accuracy and Performance of Digital Breast Tomosynthesis Compared to Mammography (ADAPT) (ADAPT)

Breast Cancer | Tumors, Breast

France, United States
GE Healthcare

Terminated

Assessment of Diagnostic Accuracy and Performance of Digital Breast Tomosynthesis Compared to Mammography (ADAPT-ENRICH)

Breast Cancer | Tumors, Breast

United States
Emory University
Novartis; Eisai Inc.

Terminated

Re-expression of ER in Triple Negative Breast Cancers

Breast Cancer | Breast Neoplasms | Breast Tumors

United States
Northwestern University
National Cancer Institute (NCI)

Withdrawn

Peripheral Stem Cell Transplantation in Treating Patients With Melanoma or Small Cell Lung, Breast, Testicular, or Kidney Cancer That is Metastatic or That Cannot Be Treated With Surgery

Kidney Cancer | Testicular Germ Cell Tumor | Breast Cancer | Lung Cancer | Melanoma (Skin)
UNICANCER
Breast International Group

Completed

Durvalumab and Endocrine Therapy in ER+/Her2- Breast Cancer After CD8+ Infiltration Effective Immune-Attractant Exposure (ULTIMATE)

Breast Cancer | Menopause | Estrogen Receptor Positive Tumor | Hormone Antagonist

France, Sweden, Spain
Suzhou Zelgen Biopharmaceuticals Co.,Ltd

Recruiting

A Study of ZG2001 in Participants With KRAS Mutated Advanced Solid Tumours

Solid Tumor | KRAS Mutation-Related Tumors

China
Karolinska University Hospital

Active, not recruiting

Therapeutic Dose Monitoring (TDM) of Tamoxifen

Breast Cancer | Breast Tumors | Breast Carcinoma | Cancer of Breast | Malignant Neoplasm of Breast

Sweden
Dartmouth-Hitchcock Medical Center

Terminated

NIR Hypoxia Imaging of Breast Tumor Response to Neoadjuvant Chemotherapy in Vivo

Breast Cancer

United States
Blaze Bioscience Inc.

Completed

Exploratory Study of Safety and ex Vivo Fluorescence of BLZ-100 in Adult Subjects With Solid Tumors Undergoing Surgery

Tumors, Breast

United States
Institut Claudius Regaud

Active, not recruiting

Comparison of Biological Features Between pN0 Triple Negative Breast Tumours With Size < or = 10 mm (pT1a/b) Versus pT1c T2 < or = 30 mm (COCABIO000)

Triple Negative Breast Cancers Without Lymph-node Involvement and < or = 30 mm

France
TYK Medicines, Inc

Recruiting

A Study of TY-302 in Patients With Advanced Solid Tumors

Breast Cancer | Solid Tumor

China
Poitiers University Hospital

Recruiting

Interest of Circulating Tumor DNA in Digestive and Gynecologic/Breast Cancer

Breast Cancer | Gynecologic Cancer | Circulating Tumor DNA | Digestive Cancer | Exosomes

France
Yonsei University

Terminated

Comparison of the Effect of Total Intravenous Anesthesia and Inhalation Anesthesia on Cancer Cell Cytotoxicity, Micrometastasis and Recurrence of Tumor in Patients Undergoing Breast Tumor Resection

Breast Cancer

Korea, Republic of

Clinical Trials on Breast Tumor

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