Clinical Trials on C. Difficile Infection in Canada

Total 3284 results

Janssen Research & Development, LLC

Completed

Study to Assess Efficacy, Safety, Tolerability and Pharmacokinetics of Simeprevir, Daclatasvir and Sofosbuvir in Treatment-naive Participants With Chronic Hepatitis C Virus Genotype 1 Infection (ACCORDION-1)

Hepatitis C Virus

United States, Canada
Gilead Sciences

Completed

Safety and Efficacy of Ledipasvir/Sofosbuvir (LDV/SOF) Fixed Dose Combination Tablet With Ribavirin for 12 Weeks in Treatment-naive Adults With Chronic HCV Genotype 3 Infection

Hepatitis C Virus Infection

Canada
Rebiotix Inc.

Completed

Microbiota Restoration Therapy for Recurrent Clostridium Difficile Infection

Clostridium Difficile Infection

United States, Canada
University of British Columbia
Canadian Institutes of Health Research (CIHR)

Completed

Evaluation of Meningococcal C Vaccine Programmes in Canadian Children

Meningococcal Sero-type C Infection

Canada
Actelion

Terminated

Comparison of Cadazolid Versus Vancomycin in Children With Clostridium Difficile-associated Diarrhea (CDAD)

Clostridium Difficile Infection

United States, Belgium, Canada, Czechia, Hungary, Italy, Poland, Romania, Spain
Jordan Feld
University Health Network, Toronto

Recruiting

Transplantation Using Hepatitis C Positive Donors, A Safety Trial

Hepatitis C | Kidney Transplant Infection | Heart Transplant Infection | Lung Transplant Infection | Kidney Pancreas Infection

Canada
Centre hospitalier de l'Université de Montréal...
Hoffmann-La Roche; Centre de Recherche du Centre Hospitalier de l'Université...

Completed

Ribavirin Dose Optimization for the Treatment of Hepatitis C

Chronic Hepatitis C

Canada
Digna Biotech S.L.

Completed

A Phase I/II Clinical Trial With Interferon Alfa 5 in Treatment-Experienced Patients With Genotype-1 Chronic Hepatitis C

Chronic Hepatitis C Virus Infection | Genotype 1 | Treatment-Experienced Patients | Relapses

Spain
Memorial University of Newfoundland

Withdrawn

Fecal Microbiota Transplantation for Primary Clostridium Difficile Diarrhea

Clostridium Difficile

Canada
Actelion

Completed

Efficacy, Safety and Tolerability of Cadazolid in Subjects With Clostridium Difficile Associated Diarrhea (CDAD)

Clostridium Difficile Infection

United States, Canada, Germany, Italy, Sweden, United Kingdom
Seres Therapeutics, Inc.

Completed

ECOSPOR III - SER-109 Versus Placebo in the Treatment of Adults With Recurrent Clostridium Difficile Infection (ECOSPORIII)

Clostridium Difficile Infection

United States, Canada
OPKO Health, Inc.

Completed

Study in Non-responder Hepatitis C Genotype 1 Patients With EMZ702, Pegylated Interferon and Ribavirin

Hepatitis, Viral, Human | Chronic Hepatitis C

Canada
Summit Therapeutics
Wellcome Trust

Completed

A Study of SMT19969 Compared With Vancomycin for the Treatment of Clostridium Difficile-Associated Diarrhoea (CDAD)

Clostridium Difficile Infection

United States, Canada
Ottawa Hospital Research Institute
Gilead Sciences; CIHR Canadian HIV Trials Network

Completed

HIV Drug Switch Followed by HCV Therapy in HIV-HCV Co-Infection (CTN289)

Hepatitis C, Chronic | Human Immunodeficiency Virus

Canada
Shire

Completed

Safety and Efficacy Study of VP20621 for Prevention of Recurrent Clostridium Difficile Infection

Clostridium Difficile Infection

United States, Belgium, Canada, Germany, Switzerland, Spain
Gilead Sciences

Completed

A Study of Response-Guided Duration of Combination Therapy With GS-9190, GS-9256, Pegasys® and Copegus® in Previously Untreated Subjects With Genotype 1 Chronic Hepatitis C

Chronic Hepatitis C Infection

United States, Spain, United Kingdom, Canada, Germany, France, Austria, Poland, Belgium, Czech Republic, Italy
Saskatchewan Health Authority - Regina Area
Gilead Sciences

Unknown

Switch to Genvoya Followed by HCV Therapy With Epclusa Followed by Simplification of HIV Therapy With Biktarvy in Patients With HIV-HCV Co-Infected Subjects on Opioid Substitution Therapy

Hepatitis C, Chronic | HIV/AIDS | Bone Diseases, Metabolic | Opioid Dependence | HIV-1-infection | HCV Coinfection | Buprenorphine Dependence | Methadone Dependence | Co-infection

Canada
Bristol-Myers Squibb

Terminated

Efficacy and Safety Study of Pegylated Interferon Lambda-1a With Ribavirin and Daclatasvir, to Treat naïve Subjects With Chronic HCV Genotypes 1, 2, 3, and 4 Who Are Co-infected With HIV (DIMENSION)

Chronic Hepatitis C Infection

France, Germany, United States, Spain, Canada, Argentina, Mexico, Belgium, Italy, Russian Federation, United Kingdom, Poland
McMaster University
Canadian Institutes of Health Research (CIHR); Technology Evaluation in the... and other collaborators

Completed

Probiotics: Prevention of Severe Pneumonia and Endotracheal Colonization Trial (PROSPECT): A Feasibility Clinical Trial (PROSPECT)

Antibiotic-Associated Diarrhea | Ventilator Associated Pneumonia (VAP) | Other Infections | C-Difficile | Duration of Mechanical Ventilation | Length of ICU Stay | Length of Hospital Stay | ICU and Hospital Mortality

United States, Canada
Pfizer

Completed

Clostridium Difficile Vaccine Efficacy Trial (Clover)

Clostridium Difficile Infection

United States, Spain, Belgium, Taiwan, Japan, Portugal, Colombia, Korea, Republic of, Poland, Australia, Germany, Canada, Argentina, Bulgaria, Chile, Czechia, Finland, France, Hungary, Peru, Slovakia, Sweden, United Kingdom
Astellas Pharma Europe B.V.
Merck Sharp & Dohme LLC

Completed

A Study to Investigate the Safety and Efficacy of Fidaxomicin (Oral Suspension or Tablets) and Vancomycin (Oral Liquid or Capsules) in Pediatric Subjects With Clostridium Difficile-associated Diarrhea (CDAD) (SUNSHINE)

Clostridium Difficile-associated Diarrhea (CDAD)

United States, Belgium, Italy, Canada, France, Germany, Hungary, Poland, Romania, Spain
McGill University Health Centre/Research Institute...

Unknown

High Dose Insulin Therapy to Improve Liver Function

Hepatitis C Virus

Canada
ZymoGenetics

Completed

Study of PEG-rIL-29 (or PEG-IFN Lambda) in Subjects With Chronic Hepatitis C Virus Infection

Hepatitis C, Chronic

United States, Canada
Pfizer

Completed

A Study To Investigate A Clostridium Difficile Vaccine In Healthy Adults Aged 50 To 85 Years, Who Will Each Receive 3 Doses Of Vaccine.

Clostridium Difficile

United States, Canada
American Gastroenterological Association
University of Pennsylvania; University of California, San Diego; University of... and other collaborators

Recruiting

Fecal Microbiota Transplant National Registry (FMT)

Clostridium Difficile Infection | Gut Microbiome | Fecal Microbiota Transplantation

United States, Canada
Synthetic Biologics Inc.

Completed

A Study of SYN-004 for the Prevention of C.Diff in Patients With a LRTI

Clostridium Infections | Clostridium Difficile

United States, Bulgaria, Canada, Hungary, Poland, Romania, Serbia
Genzyme, a Sanofi Company

Completed

A Study of the Absorption of GT267-004 in Patients With Clostridium Difficile-Associated Diarrhea

Antibiotic-Associated Diarrhea | Pseudomembranous Colitis | Clostridium Difficile Diarrhea

Canada
University of Manitoba
Roche Pharma AG

Completed

Prospective Anti-Hepatitis C Virus (Anti-HCV) Trial of Peg-Interferon and Ribavirin in Subjects of First Nations, Metis and Caucasian Ethnicity (Praire)

Chronic Hepatitis C

Canada
Sanofi Pasteur, a Sanofi Company

Terminated

Study of a Candidate Clostridium Difficile Toxoid Vaccine in Subjects at Risk for C. Difficile Infection

Clostridium Difficile Infection

Sweden, United States, Mexico, Philippines, Singapore, Germany, France, Canada, Australia, Peru, Colombia, Brazil, Costa Rica, Denmark, Dominican Republic, Finland, Guatemala, Japan, Korea, Republic of, Panama, Poland, Puerto Rico, ... and more
University of Alberta
Novartis

Completed

Assessment of Biomarkers for Recurrent HCV Infection Post-liver Transplantation

Hepatitis C Virus

Canada
Actelion

Completed

Efficacy and Safety of Cadazolid Versus Vancomycin in Subjects With Clostridium Difficile - Associated Diarrhea

Clostridium Difficile Infection

United States, Australia, Brazil, Canada, France, Germany, Italy, Netherlands, Peru, Poland, Romania, Spain
Cubist Pharmaceuticals LLC

Completed

Study of CB-183,315 in Participants With Clostridium Difficile Infection

Diarrhea | Clostridium Difficile Infection

United States, Canada
Rebiotix Inc.

Completed

Microbiota Restoration Therapy for Recurrent Clostridium Difficile Infection (PUNCH CD3-OLS) (CD3-OLS)

Communicable Diseases | Infection | Clostridium Difficile Infection

United States, Canada
AbbVie

Completed

A Study of of Glecaprevir/Pibrentasvir in Adults With Chronic Hepatitis C Virus (HCV) Genotype 5 or 6 Infection (ENDURANCE-5 6)

Hepatitis C Virus (HCV)

United States, Australia, Belgium, Canada, France, New Zealand, Singapore, South Africa, Vietnam
BioWest Therapeutics Inc

Unknown

A Study to Evaluate the Safety, Antiviral Effect, and Pharmacokinetics of Celgosivir in Combination With Peginterferon Alfa-2b and Ribavirin in Treatment-Naïve Patients With Chronic Hepatitis C

Chronic Hepatitis C

Canada
University Health Network, Toronto
Gilead Sciences

Active, not recruiting

Lung Transplant HCV, Pilot Study

Hepatitis C | Lung Transplant Infection

Canada
Gilead Sciences

Terminated

Efficacy and Safety Study of GS-9450 Treatment for 6 Months in Patients With Chronic Hepatitis C Virus Infection

HCV Infection

United States, United Kingdom, Germany, Canada, Puerto Rico, Poland
University Health Network, Toronto

Unknown

Insulin Resistance Associated With Chronic Hepatitis C (CHC) and the Effect of Antiviral Therapy

Hepatitis B | Hepatitis C

Canada
Seres Therapeutics, Inc.

Completed

ECOSPOR IV: An Open-Label Study Evaluating SER-109 in Recurrent Clostridioides Difficile Infection

Clostridioides Difficile Infection

United States, Canada
Gilead Sciences

Completed

Efficacy and Safety of Ledipasvir/Sofosbuvir Fixed-Dose Combination for 12 Weeks in Subjects With Chronic Genotype 1 or 4 HCV and HIV-1 Co-infection

HIV | Hepatitis C Virus

United States, New Zealand, Canada, Puerto Rico
Actelion

Completed

Efficacy and Safety of Cadazolid Versus Vancomycin in Subjects With Clostridium Difficile-associated Diarrhea

Clostridium Difficile Infection

United States, Belgium, Israel, Argentina, Brazil, Canada, Chile, Croatia, Czechia, Greece, Hungary, Korea, Republic of, Romania, Slovakia
Bristol-Myers Squibb

Completed

Study to Assess the Effect of BMS-790052 on the Pharmacokinetics of Ortho Tri-Cyclen® in Healthy Female Subjects

Chronic Hepatitis C

United States, Canada
University of Calgary
Canadian Institutes of Health Research (CIHR); Roche Pharma AG

Completed

Pegylated Interferon Plus Ribavirin in the Treatment of Active and Past Intravenous Drug Users Infected With Hepatitis C

Hepatitis c

Canada
Astellas Pharma Europe B.V.

Terminated

To Determine the Feasibility of a Fidaxomicin Study in Neonates and to Assess C. Difficile (Clostridium Difficile) Involvement in the Pathogenesis (DAISY)

Clostridium Difficile

France, Germany, Netherlands, Spain
BioWest Therapeutics Inc

Completed

An Extension Study to Evaluate the Safety and Efficacy of Celgosivir and Peginterferon Alfa-2b, With or Without Ribavirin, in Patients With Chronic Hepatitis C Genotype 1 Infection

Hepatitis C, Chronic

Canada
Ottawa Hospital Research Institute
CIHR Canadian HIV Trials Network

Withdrawn

Improving Fibrosis Outcomes With Metformin

HIV Infection | Hepatitis C

Canada
Catherine Anne Chappell
Gilead Sciences

Recruiting

Sofosbuvir/Velpatasvir Treatment of Chronic Hepatitis C During Pregnancy (STORC)

Hepatitis C, Chronic | Pregnancy; Infection

United States, Canada
University Health Network, Toronto

Completed

Lifestyle Intervention Targetting Obesity and Insulin Resistance in Chronic Hepatitis C

Obesity | Hepatitis C | Metabolic Syndrome | Insulin Resistance

Canada
Gilead Sciences

Terminated

A Registry for Participants With Cirrhosis Who Achieve a Sustained Virologic Response Following Treatment With a Sofosbuvir-Based Regimen Without Interferon for Chronic Hepatitis C Infection

Hepatitis C Virus Infection

France, Spain, United States, Australia, Canada, Germany, United Kingdom, Italy, New Zealand, Puerto Rico
Gilead Sciences

Completed

Safety And Efficacy of Sofosbuvir/Velpatasvir/Voxilaprevir Fixed-Dose Combination for 12 Weeks in Adults Who Participated in a Prior Gilead-Sponsored HCV Treatment Study

Hepatitis C Virus Infection

Germany, United States, Australia, United Kingdom, Canada, France, New Zealand

Clinical Trials on C. Difficile Infection in Canada

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