Clinical Trials on CD25 Deficiency in United Kingdom

Total 4540 results

Great Ormond Street Hospital for Children NHS Foundation...

Recruiting

Lentiviral Gene Therapy for p47 AR-CGD

P47-Phox, Deficiency of

United Kingdom
Joel Puente
Crown Sport Nutrition; Go Fit Spain

Not yet recruiting

Effects of a Multi-Ingredient Pre-Workout Supplement on Body Composition, Performance, Muscular Properties, and Wellbeing in Adults.

Fatigue | Muscular Atrophy | Psychological | Protein Deficiency | Training Group, Sensitivity

United Kingdom
Joel Puente
Crown Sport Nutrition; Go Fit Spain

Completed

Effects of a Recovery Supplement on Body Composition, Performance, Muscular Properties, and Wellbeing

Fatigue | Muscular Atrophy | Psychological | Protein Deficiency | Training Group, Sensitivity

United Kingdom
Queen Mary University of London

Completed

Treatment of Iron Deficiency Anaemia in Inflammatory Bowel Disease With Ferrous Sulphate

Crohn's Disease | Ulcerative Colitis

United Kingdom
The Christie NHS Foundation Trust

Terminated

Effect of Pegvisomant on GH/IGF-I Relationship in GHD

Severe Adult Growth Hormone Deficiency

United Kingdom
University College, London

Recruiting

Halting Ornithine Transcarbamylase Deficiency With Recombinant AAV in ChildrEn (HORACE)

Ornithine Transcarbamylase Deficiency

United Kingdom
University of Liverpool
Pfizer

Unknown

Effects of Growth Hormone (GH) Deficiency and Growth Hormone Replacement on Serum Fibroblast Growth Factor 21 (FGF21)

Growth Hormone Deficiency

United Kingdom
Wave Life Sciences Ltd.

Recruiting

A Phase 1 Research Study to Evaluate Safety, Tolerability, and Pharmacokinetics of WVE-006 in Healthy Participants With Wild-type AAT Expression (RestorAATion-1) (RestorAATion-1)

Alpha-1 Antitrypsin Deficiency

United Kingdom
Wirral University Teaching Hospital NHS Trust

Completed

Measures to Increase the Effectiveness of Fast Track Colorectal Clinics for Iron Deficiency Anaemia.

Colorectal Cancer

United Kingdom
Takeda

Completed

Calcichew D3 Preference Study in Participants Eligible for Calcium and Vitamin D Supplementation.

Calcium and Vitamin D Deficiencies

United Kingdom, Germany
BioCryst Pharmaceuticals

Completed

A Drug-Drug Interaction Study to Evaluate Drug Transporter Interactions

Hereditary Angioedema

United Kingdom
Great Ormond Street Hospital for Children NHS Foundation...

Unknown

Gene Therapy for X-linked Severe Combined Immunodeficiency (SCID-X1)

X-linked Severe Combined Immunodeficiency

United Kingdom
Ultragenyx Pharmaceutical Inc

Completed

A Study of UX007 (Triheptanoin) in Participants With Long-Chain Fatty Acid Oxidation Disorders (LC-FAOD)

Long-chain Fatty Acid Oxidation Disorders (LC-FAOD) | Very Long Chain Acyl-CoA Dehydrogenase (VLCAD) Deficiency | Trifunctional Protein (TFP) Deficiency | Carnitine Palmitoyltransferase (CPT II) Deficiency | Longchain 3-hydroxy-acyl-CoA Dehydrogenase (LCHAD) Deficiency

United States, United Kingdom
KalVista Pharmaceuticals, Ltd.

Completed

Phase 1 Crossover Study in Healthy Subjects to Evaluate the PK Profile of KVD824 Following Single and Multiple Doses of Modified Release (MR) Formulations

Hereditary Angioedema

United Kingdom
KalVista Pharmaceuticals, Ltd.

Completed

A Single Dose Safety, Tolerability, Pharmacokinetic and Food Effect Study of KVD900 in Healthy Volunteers

Hereditary Angioedema

United Kingdom
BioCryst Pharmaceuticals

Completed

A Relative Bioavailability Study of Two Formulations of BCX7353

Hereditary Angioedema

United Kingdom
BioCryst Pharmaceuticals

Completed

First-in-Human Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of BCX7353 in Healthy Western and Japanese Volunteers

Hereditary Angioedema

United Kingdom
St George's, University of London
SPD Development Company Limited

Suspended

Endocrine and Menstrual Disturbances in Women With Polycystic Ovary Syndrome (PCOS) (EMDPCOS)

Obesity | Polycystic Ovary Syndrome | Vitamin D Deficiency | Insulin Resistance

United Kingdom
Takeda

Recruiting

A Study in Adults With Hereditary Angioedema (HAE) Who Currently Receive Icatibant at Home

Hereditary Angioedema (HAE)

United Kingdom
University of Bath
University of Nottingham

Active, not recruiting

Physiological and Sensory Responses to Prolonged Fasting in Humans (PRO-FAST)

Adiposity | Metabolic Disturbance | Fasting | Energy Supply; Deficiency

United Kingdom
University of Liverpool

Recruiting

An Exploratory Study of Arginine Supplementation and the Postoperative Immune REsponse (ASPIRE)

Surgery | Preterm | Nutritional Deficiency | Immune System and Related Disorders

United Kingdom
Adnan Sharif

Active, not recruiting

Frailty Intervention Trial in End-Stage Patients on Dialysis (FITNESS)

Physical Activity | Hemodialysis Complication | Nutritional Deficiency

United Kingdom
University of Nottingham
Nottingham University Hospitals NHS Trust

Recruiting

Functional and Structural Lung Imaging in Chronic Obstructive Pulmonary Disease (FASTCOPD)

Chronic Obstructive Pulmonary Disease | Alpha 1-Antitrypsin Deficiency

United Kingdom
University of Oxford
British Heart Foundation; National Institute for Health Research, United Kingdom

Completed

Iron Status and Hypoxic Pulmonary Vascular Responses

Pulmonary Arterial Hypertension | Iron Deficiency | Lung Hypoxia

United Kingdom
KalVista Pharmaceuticals, Ltd.

Completed

A Single and Multiple Doses Safety, Tolerability, Pharmacokinetics and Food Effect Study of KVD824 in Healthy Volunteers

Hereditary Angioedema

United Kingdom
BioCryst Pharmaceuticals

Completed

A Study of the Relative Bioavailability of a New Formulation of BCX4161 and the Effect of Food on BCX4161

Hereditary Angioedema

United Kingdom
Z Factor Limited
Hammersmith Medicines Research; Centessa Pharmaceuticals plc

Terminated

A Single Ascending and Repeated Dose Study of Oral ZF874 in Healthy Volunteers and PiXZ Subjects

Alpha1 Anti-Trypsin Deficiency

United Kingdom
BioCryst Pharmaceuticals

Completed

An Open-label Drug-Drug Interaction Study to Evaluate the Effect of BCX7353 on Cytochrome P450 Enzyme Activity Using Probe Substrates

Hereditary Angioedema

United Kingdom
BioCryst Pharmaceuticals

Completed

Study to Determine How BCX4161 is Metabolized and Eliminated by the Body

Hereditary Angioedema

United Kingdom
Rhythm Pharmaceuticals, Inc.

Completed

Setmelanotide in Pediatric Patients With Rare Genetic Diseases of Obesity

Bardet-Biedl Syndrome | POMC Deficiency Obesity | PCSK1 Deficiency Obesity | LEPR Deficiency Obesity

United States, Australia, Spain, United Kingdom
Great Ormond Street Hospital for Children NHS Foundation...

Recruiting

Lentiviral Gene Therapy for X-linked Severe Combined Immunodeficiency

Severe Combined Immunodeficiency, X-Linked

United Kingdom
Takeda

Recruiting

A Study of Lanadelumab in Teenagers and Adults With Hereditary Angioedema (HAE)

Hereditary Angioedema (HAE)

United Kingdom
University of Nottingham
Nottingham University Hospitals NHS Trust; Action for A-T

Completed

Whole Body MRI for Cancer Surveillance in A-T

Ataxia Telangiectasia

United Kingdom
Rhythm Pharmaceuticals, Inc.

Completed

Setmelanotide for the Treatment of Leptin Receptor (LEPR) Deficiency Obesity

Leptin Receptor Deficiency Obesity

Netherlands, Germany, United Kingdom, Canada, France, Réunion
Newcastle University
Bill and Melinda Gates Foundation; Institute of Nutrition of Central America... and other collaborators

Unknown

Liver and Bone Retinol Levels in Guatemalan Adolescents and Adults (GVAS)

Vitamin A Deficiency | Vitamin A Toxicity | Hypervitaminosis A

Guatemala, United Kingdom
Tameside General Hospital

Completed

Investigating the Role of Vitamin D in the Morbidity of COVID-19 Patients

COVID-19 | Vitamin D Deficiency

United Kingdom
Imperial College London

Terminated

Iron Deficiency and Hereditary Haemorrhagic Telangiectasia

Hereditary Haemorrhagic Telangiectasia

United Kingdom
Institute of Child Health
Great Ormond Street Hospital for Children NHS Foundation Trust

Completed

Conjugate Pneumococcal Vaccine in Ataxia Telangiectasia (AT)

Ataxia Telangiectasia (AT)

United Kingdom
Origin Biosciences

Completed

Safety & Efficacy Study of ORGN001 (Formerly ALXN1101) in Pediatric Patients With MoCD Type A Currently Treated With rcPMP

Molybdenum Cofactor Deficiency, Type A

United States, Australia, Netherlands, United Kingdom, Tunisia
Arrowhead Pharmaceuticals

Active, not recruiting

Study of Fazirsiran (TAK-999, ARO-AAT) in Patients With Alpha-1 Antitrypsin Deficiency Associated Liver Disease (AATD)

Alpha 1-Antitrypsin Deficiency

Austria, Germany, United Kingdom
Royal Surrey County Hospital NHS Foundation Trust

Completed

PeRioperative Omega Three and the Effect on ImmuNity (PROTEIN)

Colorectal Cancer | Sarcopenia | Surgery | Surgery--Complications | Surgical Site Infection | Nutritional Deficiency | Complication, Postoperative | Infected Wound | Phagocytic Dysfunction

United Kingdom
Novo Nordisk A/S

Completed

Safety and Pharmacokinetics of Recombinant Factor XIII in Healthy Volunteers

Healthy | Congenital Bleeding Disorder | Congenital FXIII Deficiency

United Kingdom
Novo Nordisk A/S

Completed

Safety and Pharmacokinetics of Recombinant Factor XIII Administration in Healthy Volunteers

Healthy | Congenital Bleeding Disorder | Congenital FXIII Deficiency

United Kingdom
National Heart and Lung Institute
Wexham Park Hospital; 4th Military Hospital

Unknown

Effect of Intravenous Ferrous Sucrose on Exercise Capacity in Chronic Heart Failure

Heart Diseases | Anemia, Iron-Deficiency | Chronic Heart Failure

Poland, United Kingdom
Bio Products Laboratory

Completed

A Multi-centre Open Study to Assess the Safety and Efficacy of Subgam®

Primary Antibody Deficiency

United Kingdom
Leiden University Medical Center
ZonMw: The Netherlands Organisation for Health Research and Development; Horizon...

Recruiting

Phase I/II Clinical Trial Stem Cell Gene Therapy in RAG1-Deficient SCID (RAG1-SCID)

Severe Combined Immunodeficiency Due to RAG1 Deficiency

Spain, Netherlands, Italy, Poland, Australia, Turkey, United Kingdom
University of Plymouth

Recruiting

Home-based Complex Intervention for Children With Ataxia Telangiectasia

Ataxia Telangiectasia | Ataxia Telangiectasia in Children

United Kingdom
Great Ormond Street Hospital for Children NHS Foundation...
Cukurova University; University of Kiel; Athens General Children's Hospital "Pan...

Active, not recruiting

Calcium Balance Studies in Children With CKD and on Dialysis (Cal-Bal)

Chronic Kidney Disease Mineral and Bone Disorder

United Kingdom
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Bortezomib and Chemotherapy in Treating Participants With Lymphoid Malignancies Undergoing Stem Cell Transplant

Hematopoietic and Lymphoid Cell Neoplasm | Lymphoma | CD20 Positive | Lymphocytic Neoplasm

United States
Novo Nordisk A/S

Completed

Comparison of a Blood Clotting Drug (Recombinant Factor XIII) Produced by Two Different Manufacturers in Healthy Male Subjects

Healthy | Congenital Bleeding Disorder | Congenital FXIII Deficiency

United Kingdom

Clinical Trials on CD25 Deficiency in United Kingdom

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Medical Conditions

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CROs in Germany

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