Clinical Trials on CNS Infection

Total 63841 results

Jonsson Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

Growth Factor to Prevent Oral Mucositis in Patients With Hematologic Cancer

Lymphoma | Leukemia | Multiple Myeloma and Plasma Cell Neoplasm | Radiation Toxicity | Oral Complications | Drug/Agent Toxicity by Tissue/Organ

United States
Cancer Treatment Centers of America

Completed

Combination Chemotherapy Followed by Peripheral Stem Cell Transplantation in Treating Patients With Refractory Cancer

Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Unspecified Adult Solid Tumor, Protocol Specific | Multiple Myeloma and Plasma Cell Neoplasm | Precancerous/Nonmalignant Condition

United States
University Hospital, Toulouse

Completed

The RITAI Cohort: An Observational Study on Rituximab Off-label Use for Auto-immune Disorders (RITAI)

Cryoglobulinemia | Cold Agglutinin Disease | Pemphigus | Auto-immune Thrombocytopenic Purpura | Hemolytic Auto-immune Anaemia

France
Institut Paoli-Calmettes

Completed

Fludarabine, Busulfan, and Antilymphocyte Globulin Followed by Donor Stem Cell Transplant in Treating Older Patients With Hematological Cancer

Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Multiple Myeloma and Plasma Cell Neoplasm | Myelodysplastic/Myeloproliferative Neoplasms

France
University of Arizona
National Cancer Institute (NCI)

Completed

Monoclonal Antibody Therapy in Treating Patients With Advanced Cancer

Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Unspecified Adult Solid Tumor, Protocol Specific | Multiple Myeloma and Plasma Cell Neoplasm | Precancerous/Nonmalignant Condition

United States
National Cancer Institute (NCI)

Active, not recruiting

Anti-ICOS Monoclonal Antibody MEDI-570 in Treating Patients With Relapsed or Refractory Peripheral T-cell Lymphoma Follicular Variant or Angioimmunoblastic T-cell Lymphoma

Recurrent Grade 1 Follicular Lymphoma | Recurrent Grade 2 Follicular Lymphoma | Advanced Primary Cutaneous T-Cell Non-Hodgkin Lymphoma | Recurrent Grade 3a Follicular Lymphoma | Recurrent Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma | Recurrent Mycosis Fungoides | Recurrent Primary Cutaneous... and other conditions

United States, Canada
Assistance Publique - Hôpitaux de Paris
Iltoo Pharma

Completed

Induction of Regulatory t Cells by Low Dose il2 in Autoimmune and Inflammatory Diseases (TRANSREG)

Rheumatoid Arthritis | Systemic Lupus Erythematosus | Psoriasis | Systemic Sclerosis | Crohn's Disease | Ulcerative Colitis | Idiopathic Thrombocytopenic Purpura | Autoimmune Hepatitis | Wegener's Granulomatosis | Ankylosing Spondylitis | Behcet's Disease | Takayasu's Disease | Sclerosing Cholangitis | Gougerot-sj...

France
University of Siena

Recruiting

AutoInflammatory Disease Alliance Registry (AIDA) (AIDA)

Behcet Syndrome | Uveitis | Hereditary Autoinflammatory Diseases | Schnitzler Syndrome | Scleritis | PFAPA Syndrome | Still Disease | Autoinflammatory Syndrome, Unspecified | Vexas Syndrome

Egypt, Spain, Turkey, Italy, Saudi Arabia, Greece, Belgium, United States, Algeria, Brazil, Germany, Ghana, Iran, Islamic Republic of, Lebanon, Morocco, Poland, Portugal, Romania, Taiwan
University of North Carolina, Chapel Hill
The Hospital for Sick Children; Washington University School of Medicine; McGill... and other collaborators

Recruiting

Defining the Genetic Etiology of Suppurative Lung Disease in Children and Adults

Primary Ciliary Dyskinesia | Kartagener Syndrome | Primary Immune Deficiency

United States, Canada
Baylor College of Medicine
The Methodist Hospital Research Institute

Recruiting

Binary Oncolytic Adenovirus in Combination With HER2-Specific Autologous CAR VST, Advanced HER2 Positive Solid Tumors (VISTA)

Breast Cancer | Gastric Cancer | Colorectal Cancer | Esophageal Cancer | Pancreatic Adenocarcinoma | Lung Cancer | Solid Tumor | Bladder Cancer | Head and Neck Squamous Cell Carcinoma | Cancer of the Salivary Gland

United States
Western Sydney Local Health District

Recruiting

Cold Snare Polypectomy for Duodenal Adenomas in Familial Adenomatous Polyposis (COPDA)

Familial Adenomatous Polyposis

Australia
Mayo Clinic

Completed

Immunogenicity and Safety of Commercially Available Vaccines Against SARS-CoV-2 (COVID-19) in Patients With Hematologic Malignancies

Hodgkin Lymphoma | B-cell Non Hodgkin Lymphoma | Monoclonal B-Cell Lymphocytosis | Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

United States
Hospital Clinic of Barcelona

Unknown

Dexmedetomidine to Improve Outcomes of ARDS in Critical Care COVID-19 Patients (COVID-DEX)

Inflammation | Acute Respiratory Distress Syndrome | Dexmedetomidine | Cytokine Storm | Delirium, Emergence
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Withdrawn

Alemtuzumab Plus Fludarabine and Melphalan With or Without Cyclosporine, Mycophenolate Mofetil, and Low-Dose Total-Body Irradiation Therapy Followed by Donor Peripheral Stem Cell Transplant in Treating Patients With Hematologic Cancer

Lymphoma | Myelodysplastic Syndromes | Leukemia | Multiple Myeloma and Plasma Cell Neoplasm | Myelodysplastic/Myeloproliferative Neoplasms

United States
Hannah Brown Amoakoh
University of Ghana; Ghana Health Services

Completed

Evaluating the Effects of SMS Text Messaging Support System Among Frontline Health Workers in Ghana (Accelerate)

Eclampsia | Asphyxia | Neonatal Jaundice | Postpartum Haemorrhage | Pre-eclampsia | Maternal Death | Neonatal Sepsis | Neonatal Death | Pregnancy Induced Hypertension | Puerperal Sepsis

Ghana
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Terminated

Donor Stem Cell Transplant in Treating Patients With Relapsed Hematologic Malignancies or Secondary Myelodysplasia Previously Treated With High-Dose Chemotherapy and Autologous Stem Cell Transplant

Lymphoma | Myelodysplastic Syndromes | Leukemia | Multiple Myeloma and Plasma Cell Neoplasm | Lymphoproliferative Disorder | Myelodysplastic/Myeloproliferative Neoplasms

United States
Bio Products Laboratory

Completed

A Study to Find Out How Safe and Effective Gammaplex® is in Young People With Primary Immunodeficiency

Common Variable Immunodeficiency | Wiskott-Aldrich Syndrome | X-linked Agammaglobulinemia | Primary Immune Deficiency Disorders | Hyper-IgM Syndrome

United States, Chile, Israel
Clatterbridge Centre for Oncology

Unknown

Early Hospital Discharge or Standard Inpatient Care in Cancer Patients Receiving Antibiotics for Febrile Neutropenia

Lymphoma | Small Intestine Cancer | Neutropenia | Brain and Central Nervous System Tumors | Unspecified Adult Solid Tumor, Protocol Specific | Psychosocial Effects of Cancer and Its Treatment

United Kingdom
University of Kentucky

Completed

Phase I/II Study of Escalating-Dose Melphalan w/Autologous SCS & Amifostine Cytoprotect

Sarcoma | Lymphoma | Leukemia | Breast Cancer | Ovarian Cancer | Unspecified Adult Solid Tumor, Protocol Specific | Neuroblastoma

United States
Northside Hospital, Inc.
Blood and Marrow Transplant Group of Georgia

Completed

Early Administration of ATG Followed by Cyclophosphamide, Busulfan and Fludarabine Before a Donor Stem Cell Transplant in Patients With Hematological Cancer

Lymphoma | Kidney Cancer | Myelodysplastic Syndromes | Leukemia | Myeloproliferative Disorders | Multiple Myeloma and Plasma Cell Neoplasm | Myelodysplastic/Myeloproliferative Diseases

United States
Northwestern University
National Cancer Institute (NCI)

Completed

Bone Marrow and Peripheral Stem Cell Transplantation in Treating Patients With Hematologic Cancer

Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Multiple Myeloma and Plasma Cell Neoplasm | Graft Versus Host Disease | Precancerous/Nonmalignant Condition

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Sirolimus, Tacrolimus, and Methotrexate in Preventing Acute Graft-Versus-Host Disease in Patients With Hematologic Cancer Who Are Undergoing Donor Stem Cell Transplantation

Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Multiple Myeloma and Plasma Cell Neoplasm | Myelodysplastic/Myeloproliferative Diseases | Graft Versus Host Disease

United States
Sidney Kimmel Comprehensive Cancer Center at Johns...
National Cancer Institute (NCI)

Completed

Cyclophosphamide Plus Bone Marrow Transplantation in Treating Patients With Hematologic Cancer

Lymphoma | Myelodysplastic Syndromes | Leukemia | Multiple Myeloma and Plasma Cell Neoplasm | Myelodysplastic/Myeloproliferative Diseases

United States
National Cancer Institute (NCI)

Completed

Vismodegib and Gamma-Secretase/Notch Signalling Pathway Inhibitor RO4929097 in Treating Patients With Advanced or Metastatic Sarcoma

Recurrent Uterine Corpus Sarcoma | Chondrosarcoma | Recurrent Osteosarcoma | Gastrointestinal Stromal Tumor | Clear Cell Sarcoma of the Kidney | Metastatic Osteosarcoma | Ovarian Sarcoma | Recurrent Adult Soft Tissue Sarcoma | Stage III Adult Soft Tissue Sarcoma | Stage III Uterine Sarcoma | Stage IV Adult... and other conditions

United States
Universitätsklinikum Hamburg-Eppendorf

Terminated

Chronical Illness-related Limitations of the Ability to Cope With Rising Temperatures: an Observational Study (CLIMATE)

Depressive Disorder | Myocardial Infarction | Heart Failure | Stroke | Coronary Disease | Diabetes Mellitus, Type 2 | Renal Insufficiency | Diabetes Mellitus, Type 1 | Schizophrenia | Pulmonary Disease, Chronic Obstructive | Peripheral Nervous System Diseases | Anxiety Disorders | Ischemic Attack, Transient | Arrhythmias... and other conditions

Germany
MD Stem Cells

Recruiting

Neurologic Stem Cell Treatment Study (NEST)

Stroke | Nervous System Diseases | Diabetic Neuropathies | Neurodegenerative Diseases | Cognitive Impairment | Amyotrophic Lateral Sclerosis | Dementia | Neurological Disorders | Alzheimer Disease | ALS | Traumatic Brain Injury | Cerebral Infarction | Lewy Body Disease | Cerebral Hemorrhage | Frontotemporal Dementia | Progressive... and other conditions

United States, United Arab Emirates
Lei Li

Recruiting

Genetic Mutation in Epithelial Ovarian Cancer

Epithelial Ovarian Cancer | Microsatellite Instability | PD-L1 | Nucleotide Variant | Copy Number Variation | Insertion-deletion Variation | Genomic Structural Variation | Total Mutation Burden | PD-1

China
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Cyclophosphamide for Prevention of Graft-Versus-Host Disease After Allogeneic Peripheral Blood Stem Cell Transplantation in Patients With Hematological Malignancies

Stage III Multiple Myeloma | Chronic Myelomonocytic Leukemia | Recurrent Adult Acute Myeloid Leukemia | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma and other conditions

United States
University of Southern California
Wyeth is now a wholly owned subsidiary of Pfizer

Completed

Temsirolimus and Vinorelbine Ditartrate in Treating Patients With Unresectable or Metastatic Solid Tumors

Recurrent Prostate Cancer | Stage III Renal Cell Cancer | Recurrent Endometrial Carcinoma | Male Breast Cancer | Stage IV Breast Cancer | Stage IV Ovarian Epithelial Cancer | Stage IV Ovarian Germ Cell Tumor | Stage IIIA Non-small Cell Lung Cancer | Stage IIIB Non-small Cell Lung Cancer | Stage IIIA Breast... and other conditions

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Fludarabine Phosphate, Low-Dose Total-Body Irradiation, and Donor Stem Cell Transplant Followed by Cyclosporine, Mycophenolate Mofetil, Donor Lymphocyte Infusion in Treating Patients With Hematopoietic Cancer

Stage II Multiple Myeloma | Stage III Multiple Myeloma | Chronic Myelomonocytic Leukemia | Recurrent Adult Acute Myeloid Leukemia | Juvenile Myelomonocytic Leukemia | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult... and other conditions

United States, Italy
City of Hope Medical Center
National Cancer Institute (NCI)

Active, not recruiting

Pembrolizumab and Pralatrexate in Treating Patients With Relapsed or Refractory Peripheral T-Cell Lymphomas

Anaplastic Large Cell Lymphoma | Recurrent Angioimmunoblastic T-Cell Lymphoma | Recurrent Mycosis Fungoides | Refractory Angioimmunoblastic T-Cell Lymphoma | Refractory Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma | Refractory Mycosis Fungoides | Refractory Anaplastic Large Cell Lymphoma | Subcutaneous... and other conditions

United States
Rigshospitalet, Denmark

Not yet recruiting

Enhancing Lung Health in Kids With Structural Lung Damage and Malformations: Azithromycin (AZI) for Airway Infection Prevention (TRALULALA-AZI)

Bronchiectasis | Bronchopulmonary Dysplasia (BPD) | Tracheomalacia | Cystic Lung Disease | Vascular Ring | Chronic Atelectasis
Amgen

Recruiting

A Study of Apremilast in Children With Oral Ulcers Associated With Behçet's Disease or Juvenile Psoriatic Arthritis

Juvenile Psoriatic Arthritis | Behçet's Disease

Spain, Turkey, Israel, Greece
University College, London
Ministry of Health and Child Welfare, Zimbabwe; Biomedical Research and Training... and other collaborators

Recruiting

Evaluating the NeoTree in Malawi and Zimbabwe

Neonatal Encephalopathy | Prematurity | Neonatal Seizure | Neonatal Jaundice | Neonatal Sepsis | Neonatal Death | Neonatal Respiratory Failure | Neonatal Hypoglycemia | Neonatal Disorder | Neonatal Hypothermia

Zimbabwe, Malawi
UNC Lineberger Comprehensive Cancer Center
National Cancer Institute (NCI)

Recruiting

Tissue, Blood, and Body Fluid Sample Collection From Patients With Hematologic Cancer

Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Multiple Myeloma and Plasma Cell Neoplasm | Nonmalignant Neoplasm | Lymphoproliferative Disorder | Myelodysplastic/Myeloproliferative Neoplasms

United States
National Cancer Institute (NCI)

Completed

M7824 in Subjects With HPV Associated Malignancies

Cervical Cancer | Anal Cancer | Oropharyngeal Cancer | Human Papilloma Virus | Vaginal or Penile Cancer

United States
National Cancer Institute (NCI)

Completed

Immunotherapy Using Tumor Infiltrating Lymphocytes for Patients With Metastatic Human Papillomavirus-Associated Cancers

Cervical Cancer | Anal Cancer | Vaginal Cancer | Oropharyngeal Cancer | Penile Cancer

United States
Memorial Sloan Kettering Cancer Center
National Cancer Institute (NCI); Dana-Farber Cancer Institute

Completed

Sunitinib in Treating Patients With Metastatic, Locally Advanced, or Locally Recurrent Sarcomas

Sarcoma | Small Intestine Cancer | Ovarian Cancer | Endometrial Cancer | Desmoid Tumor | Adult Malignant Fibrous Histiocytoma of Bone

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Completed

A Standardized Nursing Intervention Protocol for HCT Patients

Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Multiple Myeloma and Plasma Cell Neoplasm | Psychosocial Effects of Cancer and Its Treatment | Myelodysplastic/Myeloproliferative Neoplasms | Therapy-related Toxicity

United States
UNC Lineberger Comprehensive Cancer Center
National Cancer Institute (NCI)

Completed

Doxorubicin Hydrochloride Liposome and Bortezomib in Treating Patients With Refractory Hematologic Cancer or Malignant Solid Tumor or Metastatic Breast Cancer

Lymphoma | Leukemia | Breast Cancer | Ovarian Cancer | Unspecified Adult Solid Tumor, Protocol Specific | Multiple Myeloma and Plasma Cell Neoplasm

United States
Sidney Kimmel Comprehensive Cancer Center at Johns...
National Cancer Institute (NCI)

Completed

Cyclophosphamide and/or Mycophenolate Mofetil With or Without Tacrolimus in Treating Patients Who Are Undergoing a Donor Bone Marrow or Peripheral Stem Cell Transplant for Hematologic Cancer

Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Multiple Myeloma and Plasma Cell Neoplasm | Myelodysplastic/Myeloproliferative Diseases | Graft Versus Host Disease

United States
Eunice Kennedy Shriver National Institute of Child...
University of Washington

Unknown

Study of Genetic and Molecular Defects in Primary Immunodeficiency Disorders

Wiskott-Aldrich Syndrome | Leukocyte Adhesion Deficiency Syndrome | X-Linked Agammaglobulinemia | X-Linked Hyper IgM Syndrome

United States
University of Chicago
National Cancer Institute (NCI)

Completed

Donor T Cells After Donor Stem Cell Transplant in Treating Patients With Hematologic Malignancies

Recurrent Adult Acute Myeloid Leukemia | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent... and other conditions

United States
University of Haifa
Bnai Zion Medical Center; Clalit Health Services, Haifa and West Galilee

Not yet recruiting

Risk and Clinical Consequences of Low Count Monoclonal B-cell Lymphocytosis (LC MBL) (MBL RiskConseq)

Cardiovascular Diseases | Infections | Autoimmune Diseases | Parkinson Disease | Dementia | Alzheimer Disease | Chronic Lymphocytic Leukemia | Monoclonal B-Cell Lymphocytosis | Cancers
Princess Anna Mazowiecka Hospital, Warsaw, Poland
Medical University of Warsaw

Not yet recruiting

The High Initial Dose of Monitored Vitamin D Supplementation in Preterm Infants. (HIDVID)

Nephrolithiasis | Vitamin D Deficiency | Metabolic Bone Disease | Osteopenia of Prematurity | Late-Onset Neonatal Sepsis

Poland
NexImmune Inc.

Not yet recruiting

Autologous T Cells Targeting HPV16 HPV18 & Survivin in Patients With R/R HPV-related Oropharyngeal Cancers

Head and Neck Cancer | Head and Neck Squamous Cell Carcinoma | Oropharyngeal Squamous Cell Carcinoma | Oropharyngeal Cancer | Human Papilloma Virus | Head and Neck Cancer Metastatic | HPV-Related Squamous Cell Carcinoma | Oropharyngeal Cancer, Metastatic | HPV-Related Mucosal Head and Neck Squamous... and other conditions
Chinese University of Hong Kong
Hong Kong Children's Hospital; Hong Kong Young Women's Christian Association

Recruiting

PACT Programme for Parents of Children With SHCN

Gastrointestinal Diseases | Vascular Diseases | Urologic Diseases | Neurodevelopmental Disorders | Autism Spectrum Disorder | Cleft Lip and Palate | Attention Deficit Hyperactivity Disorder | Developmental Delay

Hong Kong
Mayo Clinic
National Cancer Institute (NCI)

Recruiting

Vaccine Therapy in Treating Patients With Malignant Peripheral Nerve Sheath Tumor That is Recurrent or Cannot Be Removed by Surgery

Neurofibromatosis Type 1 | Metastatic Malignant Peripheral Nerve Sheath Tumor | Recurrent Malignant Peripheral Nerve Sheath Tumor

United States
King's College Hospital NHS Trust
King's College London

Completed

SELF-BREATHE RCT for Chronic Breathlessness

Liver Failure | Cancer | Asthma | Renal Failure | Cystic Fibrosis | Chronic Heart Failure | Sickle Cell Disease | Interstitial Lung Disease | COPD | Dyspnea | Post COVID-19 | Bronchiectasis Adult

United Kingdom
University of Southampton
BioNTech SE

Completed

HARE-40: HPV Anti-CD40 RNA vaccinE (HARE-40)

Unknown Primary Tumors | Head and Neck Neoplasm | Cervical Neoplasm | Penile Neoplasms Malignant | Human Papilloma Virus Related Carcinoma

United Kingdom

Clinical Trials on CNS Infection

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Slovakia

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations