Clinical Trials on CNS Neoplasm

Total 110899 results

Fundacion Clinic per a la Recerca Biomedica

Completed

2-(1-{6-[(2-[F-18]Fluoroethyl) (Methyl)Amino]-2-naphthyl} Ethylidene) Malononitrile-PET for in Vivo Diagnose of Tauopathy in Unclassified Parkinsonism ([F18]-FDDNP)

Parkinsonism | Progressive Supranuclear Palsy | Multi-System Atrophy

Spain
VA Office of Research and Development
Baylor College of Medicine

Completed

A Culturally Sensitive Values-Guided Aid for End of Life Decision-Making (Aim3)

Chronic Obstructive Pulmonary Disease | Lung Cancer | Chronic Kidney Disease | Cirrhosis | Congestive Heart Failure | Colon Carcinoma

United States
Pontifical Catholic University of Argentina

Completed

Clinical Registry of Patients Under Treatment With Atypical Antipsychotics

Schizophrenia | Major Depressive Disorder | Bipolar Depressive Disorder | Parkinson's Disease With Hallucinations
Sheba Medical Center

Completed

Amantadine for Improving Neurologic Symptoms in Ataxia-Telangiectasia

Fatigue | Ataxia | Dystonia | Parkinsonism | Chorea

Israel
National Institute of Dental and Craniofacial Research...

Completed

A Study of the Effects of Pegvisomant on Growth Hormone Excess in McCune-Albright Syndrome

McCune Albright Syndrome | Polyostotic Fibrous Dysplasia

United States
University of Colorado, Denver

Active, not recruiting

Prospective Evaluation of the Efficacy and Safety of Submucosal Endoscopy

Gastroparesis | Zenker's Diverticulum | Hirschsprung's Disease | Esophageal Obstruction | Gastrointestinal Neoplasia | Spastic Esophageal Disorders

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Withdrawn

Genetically Modified Peripheral Blood Stem Cell Transplant in Treating Patients With HIV-Associated Non-Hodgkin or Hodgkin Lymphoma

Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent Adult Diffuse Small Cleaved Cell Lymphoma and other conditions

United States
National Cancer Institute (NCI)

Completed

17-DMAG in Treating Patients With Metastatic or Unresectable Solid Tumors or Lymphomas

Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent Adult Diffuse Small Cleaved Cell Lymphoma and other conditions

United States
National Cancer Institute (NCI)

Completed

MS-275 and Isotretinoin in Treating Patients With Metastatic or Advanced Solid Tumors or Lymphomas

Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent Adult Diffuse Small Cleaved Cell Lymphoma and other conditions

United States
Mayo Clinic
National Cancer Institute (NCI)

Completed

Panobinostat in Treating Patients With Relapsed or Refractory Non-Hodgkin Lymphoma

Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Lymphoblastic Lymphoma | Recurrent Grade 1 Follicular Lymphoma | Recurrent Grade... and other conditions

United States
Sidney Kimmel Cancer Center at Thomas Jefferson...
Genentech, Inc.; Pharmacyclics LLC.

Recruiting

Obinutuzumab and Ibrutinib as Front Line Therapy in Treating Patients With Indolent Non-Hodgkin's Lymphomas

Non-Hodgkin's Lymphoma | Indolent Non-hodgkin Lymphoma | Ann Arbor Stage II Extranodal Marginal Zone Lymphoma of Mucosa-Associated Lymphoid Tissue | Ann Arbor Stage II Follicular Lymphoma | Ann Arbor Stage II Nodal Marginal Zone Lymphoma | Ann Abor Stage III B-Cell Non-Hodgkin Lymphoma | Ann Arbor... and other conditions

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Withdrawn

CpG-STAT3 siRNA CAS3/SS3 and Localized Radiation Therapy for the Treatment of Relapsed/Refractory B-Cell NHL

Recurrent Grade 1 Follicular Lymphoma | Recurrent Grade 2 Follicular Lymphoma | Recurrent Grade 3 Follicular Lymphoma | Recurrent Mantle Cell Lymphoma | Recurrent Marginal Zone Lymphoma | Refractory B-Cell Non-Hodgkin Lymphoma | Recurrent Small Lymphocytic Lymphoma | Recurrent B-Cell Non-Hodgkin... and other conditions

United States
Northwestern University
National Cancer Institute (NCI); Celgene

Active, not recruiting

Romidepsin and Lenalidomide in Treating Patients With Previously Untreated Peripheral T-Cell Lymphoma

Peripheral T-cell Lymphoma | Anaplastic Large Cell Lymphoma | Angioimmunoblastic T-cell Lymphoma | Adult Nasal Type Extranodal NK/T-cell Lymphoma | Hepatosplenic T-cell Lymphoma | Stage III Cutaneous T-cell Non-Hodgkin Lymphoma | Stage IV Cutaneous T-cell Non-Hodgkin Lymphoma | Stage I Cutaneous... and other conditions

United States
National Cancer Institute (NCI)

Completed

Vorinostat and Combination Chemotherapy With Rituximab in Treating Patients With HIV-Related Diffuse Large B-Cell Non-Hodgkin Lymphoma or Other Aggressive B-Cell Lymphomas

HIV Infection | Recurrent Grade 3 Follicular Lymphoma | Plasmablastic Lymphoma | Recurrent Diffuse Large B-Cell Lymphoma | Primary Effusion Lymphoma | AIDS-Related Primary Effusion Lymphoma | Ann Arbor Stage I Diffuse Large B-Cell Lymphoma | Ann Arbor Stage II Diffuse Large B-Cell Lymphoma | Ann Arbor... and other conditions

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Radiolabeled Monoclonal Antibody Therapy, Fludarabine Phosphate, and Low-Dose Total-Body Irradiation Followed by Donor Stem Cell Transplant and Immunosuppression Therapy in Treating Older Patients With Advanced Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndromes

Chronic Myelomonocytic Leukemia | Recurrent Adult Acute Myeloid Leukemia | Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities | Adult Acute Myeloid Leukemia With Del(5q) | Adult Acute Myeloid Leukemia With Inv(16)(p13;q22) | Adult Acute Myeloid Leukemia With t(16;16)(p13;q22) | Adult... and other conditions

United States
Rondeep Brar
National Cancer Institute (NCI)

Completed

CPX-351 in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Syndrome

Recurrent Adult Acute Myeloid Leukemia | Adult Acute Megakaryoblastic Leukemia (M7) | Adult Acute Minimally Differentiated Myeloid Leukemia (M0) | Adult Acute Myeloblastic Leukemia With Maturation (M2) | Adult Acute Myeloblastic Leukemia Without Maturation (M1) | Adult Acute Myeloid Leukemia... and other conditions

United States
National Cancer Institute (NCI)

Completed

Alvocidib, Cytarabine, and Mitoxantrone in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia

Adult Acute Megakaryoblastic Leukemia (M7) | Adult Acute Minimally Differentiated Myeloid Leukemia (M0) | Adult Acute Monoblastic Leukemia (M5a) | Adult Acute Monocytic Leukemia (M5b) | Adult Acute Myeloblastic Leukemia With Maturation (M2) | Adult Acute Myeloblastic Leukemia Without Maturation... and other conditions

United States
National Cancer Institute (NCI)

Completed

Vorinostat in Treating Patients With Acute Myeloid Leukemia

Recurrent Adult Acute Myeloid Leukemia | Adult Acute Megakaryoblastic Leukemia (M7) | Adult Acute Minimally Differentiated Myeloid Leukemia (M0) | Adult Acute Monoblastic Leukemia (M5a) | Adult Acute Monocytic Leukemia (M5b) | Adult Acute Myeloblastic Leukemia With Maturation (M2) | Adult Acute... and other conditions

United States
Pierluigi Porcu
Millennium Pharmaceuticals, Inc.; Celgene Corporation

Completed

Bortezomib and Azacitidine in Treating Patients With Relapsed or Refractory T-Cell Lymphoma

Peripheral T-cell Lymphoma | Anaplastic Large Cell Lymphoma | Angioimmunoblastic T-cell Lymphoma | Adult Nasal Type Extranodal NK/T-cell Lymphoma | Hepatosplenic T-cell Lymphoma | Post-transplant Lymphoproliferative Disorder | Recurrent Adult T-cell Leukemia/Lymphoma | Recurrent Cutaneous T-cell... and other conditions

United States
Mayo Clinic

Completed

Everolimus and Lenalidomide in Treating Patients With Relapsed or Refractory Non-Hodgkin or Hodgkin Lymphoma

Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Grade 1 Follicular Lymphoma | Recurrent Grade 2 Follicular Lymphoma | Recurrent Grade... and other conditions

United States
Queen Mary University of London

Not yet recruiting

The Use of the CUE1 in People With Parkinson's Disease and Related Disorders

Dystonia | Multiple System Atrophy | Corticobasal Degeneration | Progressive Supranuclear Palsy | Tremor | Parkinson's Disease and Parkinsonism | Vascular Parkinsonism
Chinese University of Hong Kong

Recruiting

Localized Analysis of Normalized Distance From Scalp to Cortex and Personalized Evaluation (LANDSCAPE) (LANDSCAPE)

Parkinson Disease | Aging | Dementia Alzheimers | Depression in Old Age | Dementia Frontotemporal

Hong Kong
Fondazione IRCCS Ca' Granda, Ospedale Maggiore...

Recruiting

Prospective Evaluation of Diagnosis and Treatment of Patients With Autoimmune Cytopenias Including Autoimmune Hemolytic Anemia, Immune Thrombocytopenia, and Chronic Idiopathic/Autoimmune Neutropenia (AIHA ITP CIN)

Myelodysplastic Syndromes | Immune Thrombocytopenia | Autoimmune Hemolytic Anemia | Cold Agglutinin Disease | Autoimmune Neutropenia | Chronic Idiopathic Neutropenia

Italy
Vico Therapeutics B. V.

Recruiting

A Safety and Pharmacokinetics Trial of VO659 in SCA1, SCA3 and HD

Huntington Disease | Spinocerebellar Ataxia Type 3 | Spinocerebellar Ataxia Type 1

Israel, Germany, United Kingdom, Poland, Denmark, Netherlands, France
UNC Lineberger Comprehensive Cancer Center
National Cancer Institute (NCI)

Recruiting

Acceptability and Feasibility of Combination Treatment for Cervical Precancer Among South African Women Living With HIV (ACT2)

Cervical Cancer | Human Immunodeficiency Virus | Human Papillomavirus | CIN2 | CIN3

South Africa
Fujian Maternity and Child Health Hospital

Recruiting

Research About Impact of HPV Integration on the Prognosis of Women With Persistent HR-HPV Infection

HPV Infection | LSIL, Low-Grade Squamous Intraepithelial Lesions | HSIL, High-Grade Squamous Intraepithelial Lesions | Virus Integration

China
Xuanwu Hospital, Beijing
H. Lundbeck A/S; Hoffmann-La Roche; Millennium Pharmaceuticals, Inc.; Biogen; XINGIMAGING... and other collaborators

Recruiting

Tau Protein and SV2a Imaging in Patients With Tau Protein-related Diseases

Alzheimer Disease | Frontotemporal Dementia | Progressive Supranuclear Palsy

China
Rutgers, The State University of New Jersey

Recruiting

Using Wearable and Mobile Data to Diagnose and Monitor Movement Disorders

Parkinson Disease | Movement Disorders | Huntington Disease | Essential Tremor | Spinocerebellar Ataxias | Dystonia, Primary

United States
University of Virginia

Recruiting

Effect of Metformin on Adrenal or Ovarian Androgen Production in Overweight Pubertal Girls With Androgen Excess

Obesity | Polycystic Ovary Syndrome | Hyperandrogenemia

United States
University of Massachusetts, Amherst
University of Maryland, Baltimore; Yale University; National Institute on Aging... and other collaborators

Active, not recruiting

Cognitive Stimulation Therapy for Dementia: A Two-Armed Pragmatic Trial

Dementia | Dementia, Vascular | Dementia, Mixed | Dementia With Lewy Bodies | Dementia of Alzheimer Type | Cognitive Impairment, Mild | Dementia, Mild | Dementia Moderate | Dementia Frontal

United States
University of Washington
National Institute on Aging (NIA)

Completed

Innovations in Dementia Empowerment and Action (IDEA)

Dementia | Alzheimer Disease | Mild Cognitive Impairment | Vascular Dementia | Lewy Body Dementia | Parkinson Disease Dementia

United States
University of Milano Bicocca

Completed

Neurological Soft Signs in Neurodegenerative Dementias (DemeNSS)

Alzheimer Disease | Corticobasal Degeneration | Frontotemporal Dementia | Dementia With Lewy Bodies

Italy
University of Wisconsin, Madison
National Institute on Aging (NIA)

Completed

A Relational Research Recruitment and Engagement Intervention for Cognitive Aging Research

Cognitive Dysfunction | Dementia | Alzheimer Disease | Lewy Body Disease | Frontotemporal Dementia

United States
University of Minnesota

Enrolling by invitation

The Professional Peer Resilience Initiative (PPRI)

Stress | Stress, Psychological | Secondary Traumatic Stress | Anxiety | Post Traumatic Stress Disorder | Anxiety State | Stress Disorder | Stress Related Disorder | Trauma, Psychological | Stress Reaction | Professional Quality of Life | Stress Risk | Mental Resilience | Emotional Resilience

United States
Banc de Sang i Teixits

Completed

Efficacy and Safety Evaluation of Mesenchymal Stem Cells for the Treatment of Patients With Respiratory Distress Due to COVID-19 (COVIDMES)

COVID-19 | SARS-CoV 2 | Adult Respiratory Distress Syndrome

Spain
University of Minnesota
Indiana University

Active, not recruiting

Calcium and Phosphorus Whole-Body Balance and Kinetics in Patients With Moderate Chronic Kidney Disease

Chronic Kidney Diseases | Phosphorus and Calcium Disorders | Chronic Kidney Disease Mineral and Bone Disorder

United States
University of Oxford
Medical Research Council

Completed

Deep Brain Stimulation for Autonomic and Gait Symptoms in Multiple System Atrophy (STAG-MSA)

Multiple System Atrophy | Gait Disorders, Neurologic | Bladder, Neurogenic | Autonomic Failure | Postural Hypotension

United Kingdom
University of Texas Southwestern Medical Center

Completed

Efficacy and Safety of 10-Week or Shorter vs 12-Week or Longer Injection Intervals of Botulinum Toxin

Cervical Dystonia | Spasticity, Muscle | Hemifacial Spasm | Blepharospasm | Limb Dystonia | Fragments of Torsion Dystonia

United States
Centre Hospitalier Princesse Grace
Association de Recherche Bibliographique pour les Neurosciences

Completed

Assessment of Empathetic Process by Scanpath Study of an Artwork (EYE-EMPATH)

Parkinson Disease | Alzheimer Dementia | Fronto-Temporal Dementia

Monaco
Stanford University

Withdrawn

Alternatives to Hand Therapy for Hand Surgery Patients

Ganglion Cysts | Carpal Tunnel Syndrome | Distal Radius Fracture | Trigger Finger | Finger Fracture | De Quervain Syndrome

United States
Samsung Medical Center

Completed

Cerebellar rTMS and Physical Therapy for Cerebellar Ataxia

Spinocerebellar Ataxias | Multiple System Atrophy, Cerebellar Variant (Disorder)

Korea, Republic of
NeuroActiva, Inc.

Completed

A Double-Blind, Placebo-Controlled Safety and Efficacy Study of NA-831

Neurocognitive Disorders | Neurodegenerative Diseases | Cognitive Impairment | Alzheimer Disease | Tauopathies | Mild Cognitive Impairment | Dementia, Vascular | Dementia With Lewy Bodies | Alzheimer Dementia | Cognitive Disorder

New Zealand
Redwood Dermatology Sciences
Ultragenyx Pharmaceutical Inc

Completed

Open Label Trial Assessing Safety and Efficacy of Burosumab (KRN23), in a Patient With ENS and Hypophosphatemic Rickets

Pain, Chronic | Hypophosphatemia | Hypophosphatemic Rickets

United States
Translational Research Center for Medical Innovation...

Terminated

Clinical Study on the Safety of CNT-02 for TGCV and NLSD-M

Primary Triglyceride Deposit Cardiomyovasculopathy (TGCV) | Neutral Lipid Storage Disease With Myopathy (NLSD-M)

Italy, Japan
Herlev Hospital

Completed

Investigation of the Rewarming og the Fingers After Cooling and the Autonomic Nervous System in Raynaud's Phenomenon (RaynAUT)

Glaucoma | Diabetes Mellitus | Parkinson Disease | Autonomic Neuropathy | Raynaud Disease | Raynaud Phenomenon | Autonomic Imbalance | Hand and Arm Vibration Syndrome

Denmark
Bo Wang,MD

Unknown

Lidocaine Reduces Muscle Tremor is Beneficial for Intraoperative Recurrent Laryngeal Nerve Monitoring

Thyroid Cancer | Neck Cancer | Accessory Nerve Injuries | Recurrent Laryngeal Nerve Injuries | EMG: Repetitive Nerve Stimulation Abnormality

China
Maastricht University Medical Center
Funding: Stichting Internationaal Parkinson Fonds, The Netherlands

Completed

Transcranial Duplex Scanning and Single Photon Emission Computer Tomography (SPECT) in Parkinsonian Syndromes

Parkinson's Disease | Supranuclear Palsy, Progressive | Multiple System Atrophy | Essential Tremor | Vascular Parkinsonism | Parkinsonian Syndrome | Drug Induced Parkinsonism

Netherlands
National Institute of Mental Health (NIMH)

Completed

Evaluation and Follow-up of Individuals With Obsessive-Compulsive Disorder and Related Conditions

Anorexia Nervosa | Obsessive Compulsive Disorder | Trichotillomania | Tourette Syndrome

United States
University Hospital, Bordeaux

Completed

Assessment of Ambulatory Polygraphy in the Detection of Sleep Apnea in Multiple System Atrophy (SAMSA)

Sleep Apnea Syndromes | Multiple System Atrophy

France
Baylor College of Medicine
The Methodist Hospital Research Institute; Center for Cell and Gene Therapy...

Recruiting

Haploidentical Hematopoietic Cell Transplantation Using TCR Alpha/Beta and CD19 Depletion (HAPLOTAB)

Myelodysplastic Syndromes | Primary Immunodeficiency Diseases | Hemoglobinopathies | Chronic Myeloid Leukemia | Cytopenia | Severe Aplastic Anemia | Bone Marrow Failure Syndrome | Acute Myeloid Leukemia in Remission | Hemophagocytic Lymphohistiocytoses | Acute Lymphoblastic Leukemia in Remission | Severe...

United States

Clinical Trials on CNS Neoplasm

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