Clinical Trials on Canalicular Obstruction

Total 11668 results

AstraZeneca

Completed

Effect of Roflumilast on Exacerbation Rate in Patients With Chronic Obstructive Pulmonary Disease (COPD): The AURA Study (BY217/M2-124)

Chronic Obstructive Pulmonary Disease (COPD)

France, Germany, United Kingdom, United States, Australia, Austria, Brazil, Hungary, New Zealand, Romania, Russian Federation
AstraZeneca

Completed

The HERO-study: Effects of Roflumilast in Patients With COPD (Chronic Obstructive Pulmonary Disease) (BY217/M2-121)

Chronic Obstructive Pulmonary Disease, COPD

France, Poland, South Africa, Spain, United States, Canada, United Kingdom
UPECLIN HC FM Botucatu Unesp
Faculdade de Medicina do ABC; IEP São Lucas - Instituto de Ensino e Pesquisa; Hemocentro São Lucas and other collaborators

Unknown

Cell Therapy in Advanced Chronic Obstructive Pulmonary Disease Patients

Chronic Obstructive Pulmonary Disease (COPD)

Brazil
University of Southern Denmark
The Ministry of Science, Technology and Innovation, Denmark; Region of Southern...

Unknown

Prognosis and Treatment of COPD in Primary Care-use of Biomarkers (PROTECCT-M)

Chronic Obstructive Pulmonary Disease (COPD)

Denmark
Zhujiang Hospital
Guangzhou Institute of Respiratory Disease

Completed

Effects of CPAP Level on Respiratory Mechanics and Central Drive in Patients With COPD

Chronic Obstructive Pulmonary Disease (COPD)

China
Beijing Chao Yang Hospital

Unknown

Evaluation of Reactive Oxygen Metabolites in the Value of COPD

COPD(Chronic Obstructive Pulmonary Disease)

China
Novartis Pharmaceuticals

Completed

QVA149 Versus Fluticasone/Salmeterol in Patients With Chronic Obstructive Pulmonary Disease (COPD) (ILLUMINATE)

Chronic Obstructive Pulmonary Disease (COPD)

Spain, Germany, Estonia, Hungary, Belgium, Czech Republic, Norway, Korea, Republic of, Lithuania
Minneapolis Veterans Affairs Medical Center

Completed

Effect of Supplemental Vitamin D on Skeletal Muscle Function in Chronic Obstructive Pulmonary Disease (COPD) Patients

Chronic Obstructive Pulmonary Disease (COPD)

United States
Novartis

Completed

Safety and Tolerability of QVA149 (Indacaterol/Glycopyrrolate) Compared to Placebo and to Indacaterol in Patients With Moderate to Severe Stable Chronic Obstructive Pulmonary Disease (COPD)

Chronic Obstructive Pulmonary Disease (COPD)

France, Germany, Belgium, Spain, Turkey, Italy, Canada, Australia
GlaxoSmithKline

Completed

A Study To Investigate The Effects Of GW856553 On Patients With COPD (Chronic Obstructive Pulmonary Disease)

Pulmonary Disease, Chronic Obstructive | Chronic Obstructive Pulmonary Disease (COPD)

Germany
Novartis

Completed

Safety and Tolerability of 28 Days Treatment With Glycopyrronium Bromide (NVA237) (100 or 200 µg Once a Day) in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease

Chronic Obstructive Pulmonary Disease (COPD)

United States, Spain, Turkey, France, Netherlands, Germany
University of Milan
IRCCS Azienda Ospedaliero-Universitaria di Bologna; Valduce Hospital; Ente Ospedaliero... and other collaborators

Completed

Optimization of Ventilator Setting for Acute Exacerbations of Chronic Obstructive Pulmonary Disease (NIMV01AECB)

Acute Exacerbation of Chronic Obstructive Airways Disease

Italy, Switzerland
Mylan Inc.
Theravance Biopharma

Completed

A 42-day Parallel Group Safety Study of Revefenacin and Formoterol, Administered in Sequence and as a Combination, in Participants With COPD

Chronic Obstructive Pulmonary Disease (COPD)

United States
University Hospital, Ghent
GlaxoSmithKline; University Ghent

Completed

Pharmaceutical Care for Chronic Obstructive Pulmonary Disease (COPD) Study. (PHARMACOP)

Chronic Obstructive Pulmonary Disease (COPD)

Belgium
Optimum Patient Care
Respiratory Effectiveness Group; Boehringer Ingelheim Pharmaceutical Company... and other collaborators

Unknown

Advancing the Patient Experience in Chronic Obstructive Pulmonary Disease (APEX COPD) (APEX COPD)

Chronic Obstructive Pulmonary Disease (13645005)

United States
Swedish Intensive Care Registry

Completed

Survival After Failed First-line Non-invasive Ventilation in Acute on Chronic Obstructive Pulmonary Disease

Critical Care | Chronic Obstructive Airways Disease Exacerbated

Sweden
Poitiers University Hospital

Completed

Interest of Branched Chain Amino Acids Associated With a Respiratory Rehabilitation Program in Patients Broncho Chronic Obstructive Pulmonary Disease (REHABAAR)

Broncho Chronic Obstructive Pulmonary Disease

France
AstraZeneca

Completed

A Phase IIa Study to Investigate the Efficacy and Safety of AZD7624 in Chronic Obstructive Pulmonary Disease (COPD) Patients While on Maintenance Therapy

Chronic Obstructive Pulmonary Disease COPD

United States, Netherlands, Argentina, South Africa, Chile, Peru
Laval University
Maltais, Francois, M.D.; Saey, Didier, M.D.

Completed

Chen-style Tai Chi in Pulmonary Rehabilitation for Chronic Obstructive Pulmonary Disease

Chronic Obstructive Pulmonary Disease (COPD)

Canada
Sunovion Respiratory Development Inc.

Completed

A Long-Term Safety Trial of Treatment With Nebulized SUN-101 in Patients With COPD (GOLDEN-5)

Chronic Obstructive Pulmonary Disease (COPD)

United States, Czechia, Hungary, Russian Federation
University of Aarhus

Completed

Beetroot Juice - Effects on Performance in Chronic Obstructive Pulmonary Disease Patients (COPD)

Chronic Obstructive Pulmonary Disease Moderate

Denmark
AstraZeneca

Completed

Efficacy and Safety of Aclidinium Bromide at Two Dose Levels Versus Placebo Administered in Chronic Obstructive Pulmonary Disease (COPD) Patients

Chronic Obstructive Pulmonary Disease (COPD)

Germany, Czech Republic, France, Hungary, Italy, Peru, Poland, Russian Federation, South Africa, Spain, Ukraine
AstraZeneca

Completed

Effect of Roflumilast on Lung Function in Chronic Obstructive Pulmonary Disease (COPD) Patients Treated With Salmeterol: The EOS Study (BY217/M2-127) (EOS)

Chronic Obstructive Pulmonary Disease (COPD)

Austria, Belgium, Canada, France, Germany, Italy, Netherlands, South Africa, Spain, United Kingdom
AstraZeneca

Completed

Effect of Roflumilast on Exacerbation Rate in Patients With Chronic Obstructive Pulmonary Disease (COPD): The HERMES Study (BY217/M2-125)

Chronic Obstructive Pulmonary Disease (COPD)

Germany, Spain, United States, Canada, India, Italy, Poland, South Africa
AstraZeneca
Mitsubishi Tanabe Pharma Corporation

Completed

Efficacy and Safety of Roflumilast in Japanese Patients Older Than 40 Years With Chronic Obstructive Pulmonary Disease (APTA-2217-06)

Chronic Obstructive Pulmonary Disease (COPD)

Japan
Nuvaira, Inc.

Completed

Innovative Pulmonary Solutions (IPS) System for Targeted Lung Denervation (IPS-I)

Chronic Obstructive Pulmonary Disease (COPD)

Netherlands, South Africa
Novartis Pharmaceuticals

Completed

Comparison of Long-term Safety of the Combination Product QVA149A Against Placebo and Standard of Care Treatment in Chronic Obstructive Pulmonary Disease Patients With Moderate to Severe Airflow Limitation

Chronic Obstructive Pulmonary Disease (COPD)

Colombia, India, Korea, Republic of, Poland, Croatia, Estonia, Hungary, United Kingdom, Israel, Latvia, Turkey, Argentina, Panama, Mexico, Russian Federation, Serbia, Slovenia
AstraZeneca

Completed

Clinical Practice of AECOPD Management in China

Acute Exacerbation of Chronic Obstructive Pulmonary Disease

China
University Medical Center Groningen

Terminated

Respiratory EMG for NIV Titration in Stable COPD Patients

Chronic Obstructive Pulmonary Disease (COPD)

Netherlands
University Hospital, Tours

Completed

Evaluation of Benefit of Nebulized Bronchodilators at Home in Severe Chronic Obstructive Pulmonary Disease and Very Severe Steady State (Nebuadom)

Severe Chronic Obstructive Pulmonary Disease

France
Air Liquide Santé International
ITEC Services; Lincoln Medical and Mental Health Center

Completed

The COPD Patient Management European Trial (COMET) (COMET)

Chronic Obstructive Pulmonary Disease (COPD)

France, Spain, Germany, Italy
Aveiro University
Fundação para a Ciência e a Tecnologia

Completed

Home-monitoring and Adherence of Patients With COPD to Long-term Rehabilitation

Chronic Obstructive Pulmonary Disease (COPD)

Portugal
Universidade Federal de Pernambuco
Conselho Nacional de Desenvolvimento Científico e Tecnológico

Unknown

Whole Body Vibration in Chronic Obstructive Pulmonary Disease (COPD) Patients

Chronic Obstructive Pulmonary Disease (COPD)

Brazil
Air Force Military Medical University, China

Unknown

Study of Bosentan in the Treatment of Stable Severe Chronic Obstructive Pulmonary Disease Patients (BTCOPD)

Chronic Obstructive Pulmonary Disease (COPD)

China
Pulmatrix Inc.
Quotient Clinical

Completed

A Safety, Pharmacokinetic and Pharmacodynamic Study of PUR0200 in COPD Patients

Chronic Obstructive Pulmonary Disease (COPD)

United Kingdom
University of Edinburgh
The Dunhill Medical Trust

Completed

HELPing Older People With Very Severe Chronic Obstructive Pulmonary Disease Towards the End of Their Lives: Developing, Piloting and Refining a Practical Intervention (HELP-COPD) (HELP-COPD)

Chronic Obstructive Pulmonary Disease (COPD)

United Kingdom
Universidade Federal de Sao Carlos

Completed

Physical Training and Heart Rate Variability in COPD

Chronic Obstructive Pulmonary Disease (COPD)

Brazil
Helse Stavanger HF

Completed

Readmissions to Hospital Among Patients With COPD After Telemedicine Video Consultation - a Pilot Project

Chronic Obstructive Pulmonary Disease (COPD)

Norway
Hospital de Mataró

Completed

Urban Walking Circuits

Severe Chronic Obstructive Pulmonary Disease

Spain
GlaxoSmithKline

Completed

Safety And Anti-Inflammatory Effect Of SB681323 In Patients With Chronic Obstructive Pulmonary Disease (COPD)

Pulmonary Disease, Chronic Obstructive | Chronic Obstructive Pulmonary Disease (COPD)

Denmark, Germany, Netherlands, Finland, United Kingdom
Novartis Pharmaceuticals

Completed

Efficacy and Safety of Indacaterol Plus Tiotropium Versus Tiotropium Alone in Patients With Chronic Obstructive Pulmonary Disease (INTRUST2)

Chronic Obstructive Pulmonary Disease (COPD)

United States, Colombia, Spain, Canada, Slovakia, India, Netherlands, Czech Republic, Hungary
Novartis

Completed

Efficacy and Safety of Indacaterol in Patients With Chronic Obstructive Pulmonary Disease (COPD) Using Salmeterol as Active Control

Chronic Obstructive Pulmonary Disease (COPD)

Russian Federation, Germany, Denmark, Italy, Canada, Czech Republic, Hungary, India, Slovakia, France, Colombia, Finland, Taiwan, Iceland, Peru
Novartis Pharmaceuticals

Completed

Confirmatory Study of Indacaterol in Patients With Chronic Obstructive Pulmonary Disease (COPD)

Chronic Obstructive Pulmonary Disease (COPD)

Taiwan, Korea, Republic of, Japan, India, Hong Kong, Singapore
Strados Labs, Inc.

Withdrawn

Utility of Remote Lung Auscultation in Transitions of Care After Pulmonary Exacerbations of COPD

Chronic Obstructive Pulmonary Disease (COPD)

United States
Pulmatrix Inc.

Completed

A Phase 1b Study of PUR1800 in Patients With COPD

Chronic Obstructive Pulmonary Disease (COPD)

United Kingdom
Mylan Inc.
Theravance Biopharma

Completed

A 52-Week Parallel Group Safety Study of TD-4208 in Chronic Obstructive Pulmonary Disease (COPD)

Chronic Obstructive Pulmonary Disease (COPD)

United States
Mylan Inc.
Theravance Biopharma

Completed

Efficacy Study of Nebulized TD-4208 for Chronic Obstructive Pulmonary Disease (COPD) (COPD)

Chronic Obstructive Pulmonary Disease (COPD)

United States
Mylan Inc.
Theravance Biopharma

Completed

Efficacy Study of Nebulized TD-4208 for Chronic Obstructive Pulmonary Disease (COPD) (COPD)

Chronic Obstructive Pulmonary Disease (COPD)

United States
Chiesi Farmaceutici S.p.A.

Completed

Active Controlled Trial of CHF5993 Pressurized Metered-dose Inhaler ( pMDI) vs Symbicort®Turbuhaler® in Patients With Chronic Obstructive Pulmonary Disease ( COPD) (TRIVERSYTI)

COPD (Chronic Obstructive Pulmonary Disease)

China, Korea, Republic of, Taiwan
Hannover Medical School
CAPNETZ Stiftung

Completed

Study to Demonstrate That Antibiotics Are Not Needed in Moderate Acute Exacerbations of COPD

Chronic Obstructive Pulmonary Disease (COPD)

Germany

Clinical Trials on Canalicular Obstruction

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