Clinical Trials on Cancer, Hepatocellular

Total 53920 results

AstraZeneca
Hospital Israelita Albert Einstein

Recruiting

Brazilian Reality of Hepatocellular Carcinoma (BRA-HEP)

Hepatocellular Carcinoma | Hepatocellular Carcinoma by BCLC Stage | Hepatocellular Carcinoma Stage I | Hepatocellular Carcinoma Stage III | Hepatocellular Carcinoma Stage II

Brazil
Jonsson Comprehensive Cancer Center
Merck Sharp & Dohme LLC; Highlight Therapeutics

Terminated

BO-112 and Pembrolizumab for the Treatment of PD-1/PD-L1 Refractory Liver Cancer

Advanced Hepatocellular Carcinoma | BCLC Stage B Hepatocellular Carcinoma | BCLC Stage C Hepatocellular Carcinoma | Refractory Hepatocellular Carcinoma

United States
West China Hospital

Recruiting

Application of mRNA Immunotherapy Technology in Hepatitis B Virus-related Refractory Hepatocellular Carcinoma

Hepatocellular Carcinoma | Liver Cancer

China
M.D. Anderson Cancer Center
Genentech, Inc.

Terminated

Proton Therapy and Bevacizumab for Primary Liver Tumors

Hepatocellular Carcinoma | Cholangiocarcinoma | Liver Cancer

United States
University of Missouri-Columbia
Harry S. Truman Memorial Veterans' Hospital

Recruiting

Tumor Cell and DNA Detection in the Blood, Urine, and Bone Marrow

Gastric Cancer | Colorectal Cancer | Pancreatic Cancer | Esophageal Cancer | Non Small Cell Lung Cancer | Hepatocellular Cancer

United States
M.D. Anderson Cancer Center

Recruiting

Atezolizumab and Bevacizumab Before Surgery for the Treatment of Resectable Liver Cancer

Stage IB Hepatocellular Carcinoma AJCC v8 | Stage II Hepatocellular Carcinoma AJCC v8 | Resectable Hepatocellular Carcinoma | Stage I Hepatocellular Carcinoma AJCC v8 | Stage IA Hepatocellular Carcinoma AJCC v8

United States
Malagari Katerina

Completed

DC Bead LUMI (TM) Loaded With Doxorubicin for Intermediate Hepatocellular Carcinoma (HCC)

Hepatocellular Cancer | Chemoembolization

Greece
University of Miami
The V Foundation

Recruiting

Targeted Navigation in Hepatocellular Carcinoma (HCC)

Hepatocellular Carcinoma | Cholangiocarcinoma | Hepatobiliary Cancer

United States
Bristol-Myers Squibb

Terminated

A Study of Nivolumab and Ipilimumab and Nivolumab Alone in Combination With Trans-arterial ChemoEmbolization (TACE) in Participants With Intermediate Stage Liver Cancer (CheckMate 74W)

Cancer, Hepatocellular

China, United States, Germany, Australia, Italy, Austria, Belgium, Czechia, France, Hong Kong, Japan, Korea, Republic of, Poland, Puerto Rico, Russian Federation, Singapore, Spain, Taiwan, Canada
Mayo Clinic

Recruiting

68Ga PSMA PET Imaging for the Treatment of Advanced Liver Cancer

Advanced Hepatocellular Carcinoma | Unresectable Hepatocellular Carcinoma | Stage III Hepatocellular Carcinoma AJCC v8 | Stage IV Hepatocellular Carcinoma AJCC v8

United States
Sirtex Medical
Bright Research Partners

Recruiting

Selective Internal Radiation Therapy (SIRT) Using SIR-Spheres® Y-90 Resin Microspheres on DoR & ORR in Unresectable Hepatocellular Carcinoma Patients (DOORwaY90)

Unresectable Hepatocellular Carcinoma | BCLC Stage B Hepatocellular Carcinoma | BCLC Stage C Hepatocellular Carcinoma | BCLC Stage A Hepatocellular Carcinoma

United States
Sirtex Medical

Recruiting

Observational SIR-Spheres Study for the Treatment of Unresectable Liver Tumors (SIRtain Registry) (SIRtain)

Unresectable Hepatocellular Carcinoma (HCC) | Liver Metastases From Colorectal Cancer (mCRC)

Spain, United Kingdom, France
Beijing Tsinghua Chang Gung Hospital

Unknown

Study on the Effectiveness and Safety of Carrelizumab Combined With Apatinib Mesylate and Radiotherapy in the Treatment of Advanced Liver Cancer

Hepatocellular Carcinoma
Johns Hopkins University
King Faisal Specialist Hospital and Research Center in Riyadh (Saudi Arabia) and other collaborators

Recruiting

International Study of High-Risk Patients for Hepatocellular Carcinoma Using Liquid Biopsy (STOP-HCC)

Liver Cirrhosis | Hepatocellular Carcinoma | Liver Cancer | Early Stage Liver Cancer

Saudi Arabia, Vietnam
Suzhou Hengruihongyuan Medical Technology Co. LTD

Recruiting

To Evaluate the Safety and Efficacy of Microwave Ablation Therapy in Patients With Primary Liver Cancer

Hepatocellular Carcinoma

China
University of Southern California
National Cancer Institute (NCI)

Completed

MRI With Gadoxetate Disodium in Measuring Tumors in Patients With Liver Cancer

Advanced Adult Hepatocellular Carcinoma | Localized Non-Resectable Adult Liver Carcinoma | Adult Hepatocellular Carcinoma | BCLC Stage B Adult Hepatocellular Carcinoma | BCLC Stage C Adult Hepatocellular Carcinoma | BCLC Stage D Adult Hepatocellular Carcinoma | Localized Resectable Adult Liver... and other conditions

United States
BeiGene

Not yet recruiting

A Phase 1 Study of BGB-B2033, Alone or in Combination With Tislelizumab, in Participants With Advanced or Metastatic Solid Tumors

Metastatic Solid Tumor | Advanced Hepatocellular Carcinoma | Metastatic Hepatocellular Carcinoma | Alpha-fetoprotein (AFP)-Producing Gastric Cancer | Extragonadal Yolk Sac Tumors | Glypican-3 (GPC3)-Positive Squamous Non-small Cell Lung Cancer
Tianjin Third Central Hospital

Recruiting

Study of Microwave Spherical Ablation and Traditional Microwave Ablation in Single Hepatocellular Carcinoma ≤5cm

Hepatocellular Cancer | Prognosis | Microwave Ablation | Microwave Spherical Ablation

China
Tongji Hospital

Recruiting

PVE/PVL Combined With DEB-TACE in the Treatment of Patients With Large and Unresectable Liver Cancer (CCGLC-004)

Hepatocellular Carcinoma

China
GenVivo, Inc.

Active, not recruiting

GEN2 Directed Cancer Immunotherapy Trial (GEN2)

Hepatocellular Carcinoma | Metastatic Cancer

Philippines
Chen Xiaoping

Completed

A Long-term Survival Analysis of Different Surgical Method in Early Hepatocellular Carcinoma

Long-term Effects of Cancer Treatment

China
Sun Yat-sen University

Completed

Transcatheter Arterial Chemoembolization Combined With Sorafenib for Unresectable Hepatocellular Carcinoma

Hepatocellular Carcinoma | Face Cancer

China
Instituto do Cancer do Estado de São Paulo

Recruiting

Dose-escalation of Regorafenib in Advanced Hepatocellular Carcinoma (STRAT-aHCC)

Hepatocellular Carcinoma | Liver Cancer

Brazil
Stanford University

Completed

Feasibility 3D Perfusion Ultrasound for Liver Cancer SABR Planning and Response Evaluation

Hepatocellular Carcinoma | Liver Tumor | Liver Cancer | Liver Carcinoma

United States
H. Lee Moffitt Cancer Center and Research Institute

Terminated

Contrast-Enhanced Ultrasound for the Evaluation of Changes in Tumor Blood Flow Surrounding HAE

Hepatocellular Carcinoma | Liver Cancer

United States
Second Military Medical University

Unknown

Radical Surgery Followed by Immunotherapy Using Precision T Cells Specific to Multiple Common Tumor-Associated Antigen for the Treatment of Hepatocellular Carcinoma

Liver Cancer

China
PhytoCeutica

Completed

Study of Botanical PHY906 Plus Capecitabine for Advanced Unresectable Hepatocellular Carcinoma

Hepatocellular Carcinoma | Liver Cancer

United States, Taiwan
Ohio State University Comprehensive Cancer Center
Varian Medical Systems

Completed

Stereotactic Body Radiation Therapy and Transarterial Chemoembolization in Treating Patients With Liver Cancer That Cannot Be Removed by Surgery

Child-Pugh Class A | Stage IIIA Hepatocellular Carcinoma | Stage IIIB Hepatocellular Carcinoma | Stage IIIC Hepatocellular Carcinoma | Stage IVA Hepatocellular Carcinoma | Stage IVB Hepatocellular Carcinoma | Child-Pugh Class B

United States
Chinese PLA General Hospital
Tsinghua University

Unknown

Autologous Natural Killer T Cells Infusion for the Treatment of Cancer

Glioma | Breast Cancer | Pancreatic Cancer | Prostate Cancer | Colon Cancer | Hepatocellular Cancer | Squamous Cell Lung Cancer

China
Newcastle-upon-Tyne Hospitals NHS Trust

Completed

Assessment of Frailty in Patients With Advanced Hepatocellular Cancers (FAC-L)

Hepatocellular Cancer

United Kingdom
Hospital Sírio-Libanês

Completed

Determination of Autonomic Responses to Exposure to Electromagnetic Fields With Low Energy Modulated Frequency

Breast Cancer | Hepatocellular Carcinoma

Brazil
Teclison Ltd.

Recruiting

Combination of TATE and PD-1 Inhibitor in Liver Cancer (TATE-PD1)

Hepatocellular Carcinoma | Gastric Cancer

United States
Eli Lilly and Company
AstraZeneca

Completed

A Study of Ramucirumab (LY3009806) Plus MEDI4736 in Participants With Advanced Gastrointestinal or Thoracic Malignancies

Hepatocellular Carcinoma | Gastric Cancer | Non-Small Cell Lung Cancer | Gastroesophageal Junction Adenocarcinoma

United States, Spain, Korea, Republic of, Taiwan, Germany, Italy, France, Israel
Wake Forest University Health Sciences
Medtronic

Completed

Evaluation of Efficacy and Accuracy of Aquamantys Device in General Surgery

Pancreatectomy | Cancer, Hepatocellular

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Suspended

Nivolumab, Fluorouracil, and Interferon Alpha 2B for the Treatment of Unresectable Fibrolamellar Cancer

Stage III Hepatocellular Carcinoma AJCC v8 | Stage IIIA Hepatocellular Carcinoma AJCC v8 | Stage IV Hepatocellular Carcinoma AJCC v8 | Stage IVA Hepatocellular Carcinoma AJCC v8 | Stage IVB Hepatocellular Carcinoma AJCC v8 | Stage IIIB Hepatocellular Carcinoma AJCC v8 | Unresectable Fibrolamellar...

United States
Academic and Community Cancer Research United
National Cancer Institute (NCI)

Recruiting

Regorafenib and Durvalumab for the Treatment of High-Risk Liver Cancer

Stage III Hepatocellular Carcinoma AJCC v8 | Stage IIIA Hepatocellular Carcinoma AJCC v8 | Stage IB Hepatocellular Carcinoma AJCC v8 | Stage II Hepatocellular Carcinoma AJCC v8

United States
Mayo Clinic
National Cancer Institute (NCI)

Active, not recruiting

Stereotactic Body Proton Radiotherapy for the Treatment of Liver Cancer

Recurrent Hepatocellular Carcinoma | Stage III Hepatocellular Carcinoma AJCC v8 | Stage II Hepatocellular Carcinoma AJCC v8 | Stage I Hepatocellular Carcinoma AJCC v8

United States
University of Washington
Exelixis

Terminated

Cabozantinib and Pembrolizumab for the First-Line Treatment of Advanced Liver Cancer

Advanced Hepatocellular Carcinoma | BCLC Stage B Hepatocellular Carcinoma | BCLC Stage C Hepatocellular Carcinoma

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Pembrolizumab With or Without Elbasvir/Grazoprevir and Ribavirin in Treating Patients With Advanced Refractory Liver Cancer

Stage IIIB Hepatocellular Carcinoma AJCC v7 | Stage IIIC Hepatocellular Carcinoma AJCC v7 | BCLC Stage B Hepatocellular Carcinoma | BCLC Stage C Hepatocellular Carcinoma | Hepatitis C Infection | Stage IV Hepatocellular Carcinoma AJCC v7 | Stage III Hepatocellular Carcinoma AJCC v7 | Stage IIIA Hepatocellular... and other conditions

United States
University of Oxford
University of Nottingham; Cancer Research UK; Glasgow Caledonian University; Pe... and other collaborators

Recruiting

Prospective Cohort for Early Detection of Liver Cancer (Pearl)

Hepatocellular Carcinoma | Cirrhosis

United Kingdom
National Cancer Centre, Singapore
INTRA-IMMUSG PRIVATE LIMITED

Recruiting

Phase II Study of PRL3-ZUMAB in Advanced Solid Tumors

Hepatocellular Carcinoma | Gastric Cancer | Advanced Solid Tumor

Singapore
National Cancer Institute (NCI)

Withdrawn

Gut Microbiota in People With Hepatocellular Carcinoma (HCC)

Hepatocellular Carcinoma | Liver Neoplasm | Liver Cancer | Liver Cell Caricinoma
The Affiliated Nanjing Drum Tower Hospital of Nanjing...
KAEDI

Not yet recruiting

NKG2D CAR-T(KD-025) in the Treatment of Relapsed or Refractory NKG2DL+ Tumors

Glioma | Hepatocellular Carcinoma | Colorectal Cancer | Solid Tumor

China
Memorial Sloan Kettering Cancer Center
Johns Hopkins University; Novartis Pharmaceuticals; University of California,... and other collaborators

Completed

Study of (1) Everolimus, (2) Estrogen Deprivation Therapy (EDT) With Leuprolide + Letrozole and (3) Everolimus + EDT in Patients With Unresectable Fibrolamellar Hepatocellular Carcinoma (FLL-HCC)

Fibrolamellar Carcinoma | Fibrolamellar Liver Cancer

United States
University of Texas Southwestern Medical Center

Completed

Study of Bavituximab and Sorafenib In Patients With Advanced Liver Cancer

Hepatocellular Carcinoma | Liver Cancer

United States
Shandong Cancer Hospital and Institute

Recruiting

Radiotherapy Delays Second-line Drug Therapy for Oligo Progressive Primary Liver Cancer

Hepatocellular Carcinoma | Radiotherapy

China
Zhujiang Hospital

Recruiting

Applicability of PDOX in Patients With Primary Liver Cancer: A Randomized Controlled Trial

Hepatocellular Carcinoma Resectable

China
Tel-Aviv Sourasky Medical Center

Unknown

The Potential Role of Ga-68-PSMA in Staging, Restaging and Monitoring Response in Primary Liver Cancer: Comparison With F-18-FDG

Hepatocellular Carcinoma (HCC)
City of Hope Medical Center
National Cancer Institute (NCI)

Active, not recruiting

IRX-2, Cyclophosphamide, and Nivolumab in Treating Patients With Recurrent or Metastatic and Refractory Liver Cancer

Recurrent Hepatocellular Carcinoma | Stage IV Hepatocellular Carcinoma AJCC v8 | Stage IVA Hepatocellular Carcinoma AJCC v8 | Stage IVB Hepatocellular Carcinoma AJCC v8 | Refractory Liver Carcinoma

United States
Singlera Genomics Inc.
Fudan University; Shanghai Zhongshan Hospital; Shanghai Public Health Clinical... and other collaborators

Completed

Establishment of Molecular Classification Models for Early Diagnosis of Digestive System Cancers

Hepatocellular Carcinoma | Colorectal Cancer | Esophageal Cancer | Gastric (Stomach) Cancer

China

Clinical Trials on Cancer, Hepatocellular

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