Clinical Trials on Cancers Expressing HER-2 and/or CEA in United States
Total 1283 results
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Orum Therapeutics USA, Inc.RecruitingHER2-positive Breast Cancer | HER-2 Gene Amplification | HER2 Gene Mutation | HER-2 Protein OverexpressionUnited States
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Jazz PharmaceuticalsALX Oncology Inc.Active, not recruitingHER2-expressing CancersUnited States
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H. Lee Moffitt Cancer Center and Research InstituteTerminatedBreast Cancer | Breast Cancer, Male | HER2-positive Breast Cancer | HER-2 Gene Amplification | Breast Cancer Female | HER2 Positive Breast Carcinoma | HER-2 Protein OverexpressionUnited States
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Bellicum PharmaceuticalsSuspendedHER2-positive Breast Cancer | HER2-positive Gastric Cancer | Solid Tumor, Adult | HER-2 Gene Amplification | HER-2 Protein OverexpressionUnited States
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MedImmune LLCCompletedHER2 Expressing Breast or Gastric/Stomach CancersUnited States
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Memorial Sloan Kettering Cancer CenterNational Institutes of Health (NIH)RecruitingHER2-positive Metastatic Breast Cancer | HER-2 Protein Overexpression | HER-2 Positive Malignant Carcinoma of BreastUnited States
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QuantumLeap Healthcare CollaborativeRecruitingSolid Tumor | Metastatic Cancer | Metastatic Breast Cancer | Triple Negative Breast Cancer | HER2-positive Breast Cancer | Solid Tumor, Adult | Solid Carcinoma | HER2-positive Metastatic Breast Cancer | Progesterone Receptor-positive Breast Cancer | HER2-negative Breast Cancer | Estrogen Receptor Positive... and other conditionsUnited States
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BayerCompletedCancers With HER2 ExpressionUnited States, United Kingdom
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QuantumLeap Healthcare CollaborativeByondis B.V.WithdrawnOvarian Cancer | Metastatic Cancer | Metastatic Breast Cancer | Bladder Cancer | Triple Negative Breast Cancer | HER2-positive Breast Cancer | Gastroesophageal Adenocarcinoma | Ovarian Carcinoma | HER2-positive Gastric Cancer | Metastatic Gastrointestinal Carcinoid Tumor | HER2-positive Metastatic Breast... and other conditionsUnited States
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SWOG Cancer Research NetworkNational Cancer Institute (NCI)RecruitingAnatomic Stage IV Breast Cancer AJCC v8 | Prognostic Stage IV Breast Cancer AJCC v8 | Estrogen Receptor Positive | HER2/Neu Negative | Progesterone Receptor Positive | Elevated CA15-3 or CEA or CA27-29United States, Puerto Rico, Guam
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Medstar Health Research InstituteGenentech, Inc.TerminatedHER-2 Positive Metastatic Breast CancerUnited States
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University of Michigan Rogel Cancer CenterGenentech, Inc.CompletedHER-2 Positive Metastatic Breast CancerUnited States
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Novartis PharmaceuticalsCompletedMetastatic Breast Cancer | HER2/Neu Over-expressing Locally Advanced Breast CancerChina, United States, France, Hungary, Turkey, Japan, Germany, Singapore, Italy, Poland, Spain, United Kingdom, Thailand, Israel, Australia, Belgium, Greece, Argentina, Czech Republic, Mexico, Slovakia
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Vector OncologyEisai Inc.TerminatedHER-2 Positive Breast CancerUnited States
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University of FloridaCompletedHer 2 Positive Breast CancerUnited States
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Synta Pharmaceuticals Corp.CompletedBreast Cancer | Triple Negative Breast Cancer | HER-2 Positive Breast Cancer | ER/Progressive Response (PR) + Refractory to Prior Hormonal TreatmentSpain, United States, Argentina, Belgium, Brazil, Korea, Republic of, Peru, United Kingdom
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National Cancer Institute (NCI)CompletedBreast Cancer | Breast Neoplasms | Adenocarcinomas | Metastatic Solid Tumors Characterized by HER2/Neu ExpressionUnited States
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Silverback TherapeuticsTerminatedHER2-positive Breast Cancer | HER2-positive Gastric Cancer | HER2-positive Colorectal Cancer | HER2-expressing Non-small Cell Lung CancerUnited States
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Adrienne G. WaksEli Lilly and Company; Verastem, Inc.RecruitingBreast Cancer | Hormone Receptor-positive Breast Cancer | Hormone Receptor Positive HER-2 Negative Breast CancerUnited States
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Adrienne G. WaksGilead SciencesRecruitingBreast Cancer Female | Breast Cancer Metastatic | Her 2 Positive Breast CancerUnited States
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Zymeworks Inc.Active, not recruitingHER2-expressing CancersUnited States, Canada, Korea, Republic of, Australia
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Novartis PharmaceuticalsCompletedMetastatic Breast Cancer | HER-2 Positive Breast CancerBelgium, Netherlands, Australia, Italy, United States
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Jazz PharmaceuticalsActive, not recruitingHER2-expressing CancersUnited States, Canada, Korea, Republic of
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Georgetown UniversityUniversity of Chicago; Thomas Jefferson UniversityCompletedHormone Receptor Positive HER-2 Negative Breast CancerUnited States
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Dawn L. HershmanNational Cancer Institute (NCI); Incyte CorporationCompletedMetastatic Breast Cancer | Breast Carcinoma | HER-2 Positive Breast CancerUnited States
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Dana-Farber Cancer InstituteGenentech, Inc.Active, not recruitingBreast Cancer | Stage II Breast Cancer | HER-2 Positive Breast Cancer | Stage III Breast CancerUnited States
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Jonsson Comprehensive Cancer CenterNo longer availableNeuroendocrine Tumors | Medullary Thyroid Cancer | Carcinoid Cancer | Cancers Expressing Somatostatin ReceptorsUnited States
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AstraZenecaCompletedAdvanced Solid Malignancies | Breast Cancer - ER+, HER2 - | Breast Cancer - ER+, HER2-, PIK3CA Gene MutationUnited States, United Kingdom
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Masonic Cancer Center, University of MinnesotaActive, not recruitingTriple Negative Breast Cancer | HER2-positive Breast Cancer | TN ER-/PR-/HER2- Breast Cancer | ERany/PRany/HER2+ Breast CancerUnited States
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Kadmon Corporation, LLCTerminatedHER-2 Positive Breast Cancer | Metastatic Malignant Neoplasm to BrainUnited States
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AstraZenecaDaiichi Sankyo Co., Ltd.Active, not recruitingPart 1: Bladder, Biliary Tract, Cervical, Endometrial, Ovarian, Pancreatic Cancer, Rare Tumors, Any Tumor Type Excluding Breast, Gastric, Colorectal Cancer | Part 2: HER2 Expressing/Amplified Solid Tumors Excluding Breast, Gastric, Colorectal CancerBelgium, United States, Poland, India, Taiwan, Thailand, Korea, Republic of, Czechia, Russian Federation, United Kingdom, Spain, Australia, Canada, Italy, Netherlands
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Puma Biotechnology, Inc.Not yet recruitingMetastatic Breast Cancer | Recurrent Breast Cancer | Hormone Receptor Positive HER-2 Negative Breast CancerUnited States
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Oregon Health and Science UniversityCompletedTrifunctional Protein Deficiency | Very Long Chain Acyl Coa Dehydrogenase Deficiency | Long-chain 3-hydroxyacyl-CoA Dehydrogenase Deficiency | Carnitine Palmitoyltransferase Deficiency 2United States
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Brown UniversityAstraZenecaRecruitingEsophageal Cancer | Esophageal Adenocarcinoma | HER-2 Protein Overexpression | Gastroesophageal-junction CancerUnited States
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Eli Lilly and CompanyCompletedHER-2 Positive Breast Cancer | Hormone Receptor Positive Breast CancerSpain, United States, Korea, Republic of, Belgium, France, Germany, Italy, Australia, Argentina, Canada, United Kingdom, Mexico, Brazil, Greece
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Jazz PharmaceuticalsActive, not recruitingHER2-expressing Gastrointestinal Cancers, Including Gastroesophageal Adenocarcinoma, Biliary Tract Cancer, and Colorectal CancerUnited States, Korea, Republic of, Chile, Canada
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Ellipses PharmaRecruitingMetastatic Breast Cancer | Hormone Receptor-positive Breast Cancer | Hormone Receptor Positive HER-2 Negative Breast CancerUnited States, Spain, United Kingdom
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Cogent Biosciences, Inc.TerminatedSolid Tumor | HER-2 Protein OverexpressionUnited States
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Alliance Foundation Trials, LLC.Pfizer; Syneos Health; UNICANCER; German Breast Group; SOLTI Breast Cancer Research... and other collaboratorsActive, not recruitingHER-2 Positive Breast Cancer | Estrogen Receptor Positive Breast CancerUnited States, Spain, France, Italy, Germany, Australia, Portugal, New Zealand
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Taiho Oncology, Inc.TerminatedAdvanced Solid Tumors With HER2 Abnormalities | Advanced Solid Tumors With HER3 AbnormalitiesUnited States, Spain, France, United Kingdom
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Washington University School of MedicineUnited States Department of Defense; Aclaris Therapeutics, Inc.Not yet recruitingHormone Receptor Positive HER-2 Negative Metastatic Breast CancerUnited States
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The Methodist Hospital Research InstituteEli Lilly and CompanyRecruitingHER2-negative Breast Cancer | ER-Positive Breast CancerUnited States
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Stanford UniversityUnited States Department of DefenseRecruitingBreast Cancer | HER2-negative Breast Cancer | ER Positive Breast CancerUnited States
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Stemline Therapeutics, Inc.CompletedAdvanced ER+, HER2-Negative Breast CancerUnited States
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MedImmune LLCCompletedHormone-sensitive, HER-2 Negative Metastatic Breast CancerSpain, United States, Belgium, France, United Kingdom, Canada, Israel, Germany, Hungary, Poland, Bahamas
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Western Regional Medical CenterTerminatedHER2-positive Breast Cancer | ER-positive Breast CancerUnited States
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University of MiamiRecruitingBreast Cancer | Metastatic Breast Cancer | ER-positive Breast Cancer | HER2-negative Breast CancerUnited States
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Novartis PharmaceuticalsRecruitingLocally Advanced or Metastatic KRAS G12C-mutated NSCLC With a PD-L1 Expression <1% or a PD-L1 Expression ≥ 1% and an STK11 Co-mutationItaly, Spain, United States, France, Thailand, Malaysia, China, Germany, India, Turkey, Belgium, Argentina, Bulgaria, Netherlands, Hungary, Greece, Portugal, Austria, Singapore, Brazil, United Kingdom
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National Cancer Institute (NCI)CompletedHistologically or Cytologically Confirmed Pancreatic Ca | Unresectable or Borderline Resectable Pancreatic CaUnited States
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Galena Biopharma, Inc.CompletedBreast Cancer With Low to Intermediate HER2 ExpressionUnited States, United Kingdom, France, Israel, Germany, Canada, Russian Federation, Romania, Bulgaria, Czech Republic, Hungary, Poland, Ukraine