Clinical Trials on Carcinoma, Squamous Cell of Head and Neck in United Kingdom

Total 9161 results

University of Alabama at Birmingham

Not yet recruiting

Chemo-embolization for Head and Neck Cancer

Squamous Cell Carcinoma | SCCHN

United States
M.D. Anderson Cancer Center
Genentech, Inc.; Aventis Pharmaceuticals

Completed

Erlotinib and Docetaxel With Concomitant Boost Radiation Therapy (XRT) for Head and Neck Squamous Cell Carcinoma (HNSCC)

Head and Neck Cancer

United States
National Cancer Institute (NCI)

Completed

A Pilot Study of Paclitaxel With Radiation Therapy for Locally Advanced Head and Neck Cancer

Squamous Cell Carcinoma | Head and Neck Neoplasm

United States
IO Biotech
Merck Sharp & Dohme LLC; Theradex; Almac

Recruiting

Phase II Trial of Neoadjuvant and Adjuvant IO102-IO103 and Pembrolizumab KEYTRUDA® in Patients With Resectable Tumors

Melanoma | Squamous Cell Carcinoma of Head and Neck

United States, Australia, Denmark, Spain, France, Germany
AbbVie

Recruiting

Study to Assess Adverse Events and Pharmacokinetics in Adult Participants With Non-Small Cell Lung Cancer (NSCLC), Head and Neck Squamous Cell Carcinoma (HNSCC) and Other Solid Tumors, Receiving Intravenous (IV) Infusion of ABBV-514 Alone or in Combination With Budigalimab

Non-Small Cell Lung Cancer | Head and Neck Squamous Cell Carcinoma

United States, Israel, Japan, Korea, Republic of
University of Chicago

Completed

Pilot Study of Chemotherapy for HPV-Associated Oropharyngeal Cancer

Oropharyngeal Squamous Cell Carcinoma

United States
Providence Health & Services
Galectin Therapeutics Inc.

Completed

GR-MD-02 Plus Pembrolizumab in Melanoma, Non-small Cell Lung Cancer, and Squamous Cell Head and Neck Cancer Patients

Melanoma | Non-Small Cell Lung Cancer | Squamous Cell Carcinoma of the Head and Neck

United States
Roswell Park Cancer Institute
National Cancer Institute (NCI)

Terminated

Photoacoustic Imaging for Measuring Tumors and Normal Tissue in Patients With Head and Neck Cancer

Head and Neck Squamous Cell Carcinoma | Head and Neck Carcinoma | Radiation Therapy Recipient | Head and Neck Lymph Node | Laryngeal Neoplasm

United States
European Organisation for Research and Treatment...

Recruiting

Study Assessing The "Best of" Radiotherapy vs the "Best of" Surgery in Patients With Oropharyngeal Carcinoma (Best Of)

Oropharyngeal Cancer | Hypopharyngeal Squamous Cell Carcinoma | Supraglottic Squamous Cell Carcinoma

Spain, Belgium, Switzerland, Italy, United Kingdom, Germany, France, Poland
New Mexico Cancer Care Alliance

Recruiting

Exosome Testing as a Screening Modality for Human Papillomavirus-Positive Oropharyngeal Squamous Cell Carcinoma

Oropharyngeal Cancer

United States
Presage Biosciences
Merck Sharp & Dohme LLC

Completed

PBI-MST-01 (NCT04541108) Substudy MSD-03: Intratumoral Microdosing of Pembrolizumab Alone and With MK-0482 or MK-4830 in HNSCC or STS

Soft Tissue Sarcoma | Head and Neck Squamous Cell Carcinoma

United States
National Cancer Institute (NCI)

Completed

Lapatinib in Treating Patients With Recurrent and/or Metastatic Head and Neck Cancer

Metastatic Squamous Neck Cancer With Occult Primary | Recurrent Metastatic Squamous Neck Cancer With Occult Primary | Recurrent Squamous Cell Carcinoma of the Hypopharynx | Recurrent Squamous Cell Carcinoma of the Larynx | Recurrent Squamous Cell Carcinoma of the Lip and Oral Cavity | Recurrent... and other conditions

United States
Memorial Sloan Kettering Cancer Center

Active, not recruiting

Cabozantinib in Combination With Cetuximab in Patients With Recurrent or Metastatic Head and Neck Squamous Cell Cancer

Head and Neck Squamous Cell Cancer | Recurrent Head and Neck Squamous Cell Cancer | Metastatic Head and Neck Squamous Cell Cancer

United States
Novartis Pharmaceuticals

Completed

A Phase I Study of LJM716 in Squamous Cell Carcinoma of Head and Neck, or HER2+ Breast Cancer or Gastric Cancer

Squamous Cell Carcinoma of Head and Neck | Esophageal Squamous Cell Carcinoma | HER2 + Breast Cancer, HER2 + Gastric Cancer, Squamous Cell Carcinoma of Head and Neck, Esophageal Squamous Cell Carcinoma | HER2 + Breast Cancer | HER2 + Gastric Cancer

Taiwan, Spain, Canada, Korea, Republic of, United States
Cytovation AS
Merck Sharp & Dohme LLC

Active, not recruiting

A Study to Evaluate the Safety and Efficacy of CyPep-1 in Combination With Pembrolizumab for the Treatment of Advanced or Metastatic Cancers (Catalyst)

Advanced Breast Cancer | Advanced Melanoma | Advanced Head and Neck Squamous Cell Carcinoma

United States, France, Italy, Spain, Netherlands
National Cancer Institute (NCI)

Recruiting

Testing the Addition of an Anti-cancer Drug, Ipatasertib, to the Usual Immunotherapy Treatment (Pembrolizumab) in Patients With Recurrent or Metastatic Squamous Cell Cancer of the Head and Neck

Head and Neck Squamous Cell Carcinoma | Recurrent Head and Neck Squamous Cell Carcinoma | Recurrent Hypopharyngeal Squamous Cell Carcinoma | Recurrent Laryngeal Squamous Cell Carcinoma | Recurrent Oral Cavity Squamous Cell Carcinoma | Recurrent Oropharyngeal Squamous Cell Carcinoma | Metastatic... and other conditions

United States
National Cancer Institute (NCI)

Completed

Combination Chemotherapy With or Without Veliparib in Treating Patients With Stage IV Head and Neck Cancer

Head and Neck Squamous Cell Carcinoma | Stage IVA Oropharyngeal Carcinoma AJCC v7 | Stage IVB Oropharyngeal Carcinoma AJCC v7

United States
Abramson Cancer Center of the University of Pennsylvania

Completed

Capecitabine and Lapatinib Ditosylate in Treating Patients With Squamous Cell Cancer of the Head and Neck

Head and Neck Cancer | Recurrent Metastatic Squamous Neck Cancer With Occult Primary | Recurrent Salivary Gland Cancer | Recurrent Squamous Cell Carcinoma of the Hypopharynx | Recurrent Squamous Cell Carcinoma of the Larynx | Recurrent Squamous Cell Carcinoma of the Lip and Oral Cavity | Recurrent... and other conditions

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Image-guided Proton Therapy for the Treatment of Locally Advanced Unresectable Head and Neck Cancer

Stage III Cutaneous Squamous Cell Carcinoma of the Head and Neck AJCC v8 | Stage III Hypopharyngeal Carcinoma AJCC v8 | Stage III Laryngeal Cancer AJCC v8 | Stage III Oropharyngeal (p16-Negative) Carcinoma AJCC v8 | Unresectable Head and Neck Squamous Cell Carcinoma | Unresectable Oropharyngeal... and other conditions

United States
National Cancer Institute (NCI)

Terminated

Gefitinib and Radiation Therapy With or Without Cisplatin in Treating Patients With Stage III or Stage IV Head and Neck Cancer

Stage III Squamous Cell Carcinoma of the Hypopharynx | Stage III Squamous Cell Carcinoma of the Larynx | Stage III Squamous Cell Carcinoma of the Lip and Oral Cavity | Stage III Squamous Cell Carcinoma of the Oropharynx | Stage IV Squamous Cell Carcinoma of the Hypopharynx | Stage IV Squamous... and other conditions

United States
University of Texas Southwestern Medical Center

Terminated

HYpofractionateD RadioAblative (HYDRA) Treatment of Advanced Laryngeal Cancer (HYDRA)

Squamous Cell Carcinoma of the Larynx

United States
Repertoire Immune Medicines

Terminated

RPTR-168 in Patients With Human Papillomavirus Strain 16 (HPV-16) E6/E7 Positive Tumors and Melanoma

Melanoma | Cervical Cancer | Head and Neck Squamous Cell Carcinoma

United States
Memorial Sloan Kettering Cancer Center

Recruiting

A Study Using Human Papillomavirus (HPV) DNA Testing to Detect HPV-Related Oropharyngeal Cancer (OPC)

Oropharyngeal Cancer | HPV-Related Carcinoma | HPV Positive Oropharyngeal Squamous Cell Carcinoma

United States
University of Arizona
National Cancer Institute (NCI)

Completed

Ficlatuzumab w/wo Cetuximab in Patients w/Cetuximab-Resistant, Recurrent or Metastatic Head/Neck Squamous Cell Carcinoma

Head and Neck Cancer | Recurrent Head and Neck Squamous Cell Carcinoma | Oropharyngeal Cancer | HNSCC | Recurrent Oropharyngeal Squamous Cell Carcinoma | Stage IV Squamous Cell Carcinoma of the Lip and Oral Cavity | Stage IVA Lip and Oral Cavity Squamous Cell Carcinoma | Stage IVA Nasal Cavity and... and other conditions

United States
invoX Pharma Limited

Active, not recruiting

A Phase 1/2 Study of FS118 in Patients With Advanced Malignancies

Metastatic Cancer | Squamous Cell Carcinoma of Head and Neck | Advanced Cancer

United States, France
Fox Chase Cancer Center

Withdrawn

Everolimus, Erlotinib Hydrochloride, and Radiation Therapy in Treating Patients With Recurrent Head and Neck Cancer Previously Treated With Radiation Therapy

Tongue Cancer | Recurrent Metastatic Squamous Neck Cancer With Occult Primary | Recurrent Salivary Gland Cancer | Recurrent Squamous Cell Carcinoma of the Hypopharynx | Recurrent Squamous Cell Carcinoma of the Larynx | Recurrent Squamous Cell Carcinoma of the Lip and Oral Cavity | Recurrent Squamous... and other conditions

United States
Genmab

Completed

Zalutumumab in Patients With Non-curable Head and Neck Cancer

Head and Neck Cancer | Squamous Cell Cancer

Sweden, United Kingdom, France, Hungary, Canada, Brazil, Belgium, Lithuania, Russian Federation, Serbia, Estonia, Poland
ECOG-ACRIN Cancer Research Group
National Cancer Institute (NCI)

Recruiting

Combining Radiation Therapy With Immunotherapy for the Treatment of Metastatic Squamous Cell Carcinoma of the Head and Neck

Metastatic Head and Neck Squamous Cell Carcinoma | Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Stage IV Cutaneous Squamous Cell Carcinoma of the Head and Neck AJCC v8 | Stage IV Hypopharyngeal Carcinoma AJCC v8 | Stage IV Laryngeal Cancer AJCC v8 | Stage... and other conditions

United States
M.D. Anderson Cancer Center
Eli Lilly and Company

Completed

Pemetrexed (Alimta) in Patients With Head and Neck Squamous Cell Cancer

Head and Neck Cancer

United States
H. Lee Moffitt Cancer Center and Research Institute

Completed

IRX-2 Regimen Combined With Nivolumab in Recurrent/Metastatic Solid Tumors

Renal Cell Carcinoma | Non-Small Cell Lung Cancer | NSCLC | Solid Tumor | Metastatic Cancer | Squamous Cell Carcinoma of the Head and Neck | Urothelial Carcinoma | Squamous Cell Carcinoma | Recurrent Cancer

United States
National Cancer Institute (NCI)

Completed

Sunitinib in Treating Patients With Recurrent and/or Metastatic Head and Neck Cancer

Recurrent Metastatic Squamous Neck Cancer With Occult Primary | Recurrent Squamous Cell Carcinoma of the Hypopharynx | Recurrent Squamous Cell Carcinoma of the Larynx | Recurrent Squamous Cell Carcinoma of the Lip and Oral Cavity | Recurrent Squamous Cell Carcinoma of the Oropharynx | Recurrent... and other conditions

United States
Takeda

Recruiting

A Study of TAK-186 (Also Known as MVC-101) in Adults With Advanced or Metastatic Cancer

Colorectal Cancer | Non-small Cell Lung Cancer (NSCLC) | Squamous Cell Cancer of Head and Neck (SCCHN)

Korea, Republic of, United States, Australia
National Cancer Institute (NCI)

Completed

Anti-PD-L1/TGF-beta Trap (M7824) Alone and in Combination With TriAd Vaccine and N-803 for Resectable Head and Neck Squamous Cell Carcinoma Not Associated With Human Papillomavirus Infection

Head and Neck Cancer | Head and Neck Neoplasms

United States
National Institute on Deafness and Other Communication...

Completed

Hearing Loss and the Effects of Statin Drugs in People With Head and Neck Squamous Cell Carcinoma Treated With Cisplatin Chemoradiation

Head and Neck Neoplasms | Hyperlipidemia | Hearing Disorder

United States
Case Comprehensive Cancer Center
National Cancer Institute (NCI)

Terminated

Erlotinib Hydrochloride and Radiation Therapy in Stage III-IV Squamous Cell Cancer of the Head and Neck

Stage III Squamous Cell Carcinoma of the Hypopharynx | Stage III Squamous Cell Carcinoma of the Larynx | Stage III Squamous Cell Carcinoma of the Lip and Oral Cavity | Stage III Squamous Cell Carcinoma of the Oropharynx | Stage III Verrucous Carcinoma of the Larynx | Stage III Verrucous Carcinoma... and other conditions

United States
Icahn School of Medicine at Mount Sinai
Merck Sharp & Dohme LLC; Celldex Therapeutics

Recruiting

Vaccination With Flt3L, Radiation, and Poly-ICLC

Non-Hodgkin's Lymphoma | Metastatic Breast Cancer | Head and Neck Squamous Cell Carcinoma

United States
Emory University
National Cancer Institute (NCI); National Institutes of Health (NIH); Exelixis

Active, not recruiting

Pembrolizumab & Cabozantinib in Patients With Head and Neck Squamous Cell Cancer

Recurrent Head and Neck Squamous Cell Carcinoma | Recurrent Hypopharyngeal Squamous Cell Carcinoma | Recurrent Laryngeal Squamous Cell Carcinoma | Recurrent Oral Cavity Squamous Cell Carcinoma | Recurrent Oropharyngeal Squamous Cell Carcinoma | Stage IV Hypopharyngeal Squamous Cell Carcinoma... and other conditions

United States
Pfizer

Terminated

PF-07265028 As Single Agent And In Combination With Sasanlimab in Advanced or Metastatic Solid Tumors

Gastric Cancer | Non Small Cell Lung Cancer | Advanced Solid Tumors | Gastroesophageal Junction Cancer | Urothelial Cancer | Head and Neck Squamous Cell Carcinomas

United States, Japan
Novartis Pharmaceuticals

Terminated

Study of Safety and Efficacy of INC280 and Cetuximab, in Adult c-MET Positive mCRC and HNSCC Patients After Progression on Cetuximab or Panitumumab Therapy

Metastatic Colorectal Cancer | Squamous Cell Carcinoma of Head and Neck (SCCHN)

France, Belgium, Spain, Germany, Italy, Canada, United States
UNC Lineberger Comprehensive Cancer Center

Active, not recruiting

De-intensification of Radiation and Chemotherapy for Low-Risk HPV-related Oropharyngeal SCC: Follow-up Study

Head and Neck Neoplasms | Carcinoma, Squamous Cell | Oropharyngeal Neoplasms

United States
Inovio Pharmaceuticals

Terminated

Medpulser Electroporation With Bleomycin Study to Treat Anterior Head and Neck Squamous Cell Carcinoma

Head and Neck Cancer

United States
NYU Langone Health

Recruiting

Adaptive Treatment De-escalation in Favorable Risk HPV-Positive Oropharyngeal Carcinoma

HPV Positive Oropharyngeal Squamous Cell Carcinoma | Oropharyngeal Carcinoma

United States
Genmab

Terminated

Zalutumumab in Combination With Chemotherapy and Radiotherapy in Head and Neck Cancer

Head and Neck Cancer | Squamous Cell Cancer

Belgium, Sweden, United States, France, Netherlands
Imperial College London
Imperial College Healthcare NHS Trust

Recruiting

Volatile Organic Compounds as Breath Biomarkers in Squamous Oesophageal Neoplasms (ViSON)

Oesophageal Squamous Cell Carcinoma | Oesophageal Cancer

United Kingdom
UNC Lineberger Comprehensive Cancer Center

Completed

De-intensification of Radiation & Chemotherapy in Low-Risk Human Papillomavirus-related Oropharyngeal Squamous Cell Ca

Head and Neck Neoplasms | Carcinoma, Squamous Cell | Oropharyngeal Neoplasms

United States
Exicure, Inc.

Terminated

Intratumoral Cavrotolimod Combined With Pembrolizumab or Cemiplimab in Patients With Merkel Cell Carcinoma, Cutaneous Squamous Cell Carcinoma, or Other Advanced Solid Tumors

Advanced or Metastatic Solid Tumors | Advanced or Metastatic Merkel Cell Carcinoma | Advanced or Metastatic Cutaneous Squamous Cell Carcinoma | Advanced or Metastatic Melanoma | Advanced or Metastatic Head and Neck Squamous Cell Carcinoma

United States
Quynh-Thu Le
GlaxoSmithKline

Terminated

Lapatinib and Radiation for Stage III-IV Head and Neck Cancer Patients Who Cannot Tolerate Concurrent Chemotherapy

Head and Neck Cancer | Carcinoma, Squamous Cell | Head and Neck Cancers

United States
National Cancer Institute (NCI)

Recruiting

Phase II Trial of Immunotherapeutic HPV Vaccine PRGN-2009 With Pembrolizumab Before Standard Treatment in Subjects With Newly Diagnosed HPV-Associated Oropharyngeal Cancer

Oropharyngeal Squamous Cell Carcinoma (SCC)

United States
Brigham and Women's Hospital

Active, not recruiting

Improving Detection and Early Action for HPV-positive Oropharynx Cancer (IDEA-HPV)

HPV Positive Oropharyngeal Squamous Cell Carcinoma

United States
Cantargia AB

Completed

A Study of the Safety and Tolerance of CAN04 and Pembrolizumab in Combination With and Without Carboplatin and Pemetrexed in Subjects With Solid Tumors

Carcinoma, Non-Small-Cell Lung | Head and Neck Squamous Cell Carcinoma | Urothelial Carcinoma | Malignant Melanoma

United States

Clinical Trials on Carcinoma, Squamous Cell of Head and Neck in United Kingdom

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