Clinical Trials on Cardiometabolic Health in United Kingdom

Total 32106 results

Lupin Ltd.

Completed

A Study to Test the Safety/Tolerability of Increasing Doses of LNP1892 Versus Placebo in Healthy Male/Female Subjects

Healthy

United Kingdom
Pronova BioPharma

Completed

Bioavailability of Omega-3 Food Supplements in Healthy Subjects

Healthy

United Kingdom
Pronova BioPharma

Completed

[14C] Icosabutate -A Phase I Absorption, Metabolism and Excretion Study

Healthy

United Kingdom
Galapagos NV

Completed

Multiple Ascending Dose Study of GLPG0634 in Japanese and Caucasian Healthy Subjects

Healthy

United Kingdom
Janssen R&D Ireland

Completed

A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of TMC647055 in Combination With Ritonavir (Part 1) and the Co-administration of TMC435, TMC647055 and Ritonavir (Part 2) in Healthy Japanese Participants

Healthy

United Kingdom
LEO Pharma

Completed

LEO 22811 - Single Dose Bioavailability Study of Tablet Versus Oral Solution in Healthy Subjects

Healthy

United Kingdom
Sauflon Pharmaceuticals Ltd

Completed

Clinical Performance of All-in-One Light Multi-purpose for Silicone Hydrogel Contact Lenses

Healthy

United Kingdom
AstraZeneca

Completed

Single Oral Dose of 60 mg [14C]AZD9668 in Healthy Male Volunteers (ADME)

Healthy

United Kingdom
AstraZeneca

Terminated

Study to Investigate the Safety, Tolerability and Pharmacokinetics of Single Doses ofAZD2551

Healthy

United Kingdom
AstraZeneca

Completed

Single and Multiple Ascending Doses of AZD1981 in Japan (JSAD/JMAD)

Healthy

United Kingdom
AstraZeneca

Completed

Four-period Crossover Study to Assess the Effects of Single Oral Doses of ZD4054 (Zibotentan) (10mg and 30mg) on QTc Interval

Healthy

United Kingdom
Solvay Pharmaceuticals

Completed

Effects of Fenofibrate on Gene Expression in Healthy Volunteers

Healthy

United Kingdom
Solvay Pharmaceuticals

Completed

Safety and Tolerability of the First IV Dosing of SLV338 in Healthy Volunteers

Healthy

United Kingdom
AstraZeneca

Completed

AZD9056 Relative Bioavailability Study

Healthy

United Kingdom
University of Leicester
Medical Research Council; University Hospitals, Leicester; Loughborough University and other collaborators

Completed

Exhaled Breath Metabolomic Biomarkers in the Acutely Breathless Patient (EMBER)

Heart Failure | Healthy | Asthma | COPD | Community-acquired Pneumonia | Breathlessness

United Kingdom
Loughborough University
Bridge Farm Nurseries Limited, Spalding, UK

Recruiting

Physiological and Appetitive Effects of CBD Supplementation

Appetitive Behavior | Adverse Effect | Metabolic Health

United Kingdom
Liverpool John Moores University
University of Central Lancashire; Queen's University, Belfast; Newcastle University and other collaborators

Completed

Idea Density in Exam Performance (IDEP)

Medical Education | Health Education | Educational Assessment

United Kingdom
Incyte Corporation

Recruiting

A Study Assessing the Mass Balance, Pharmacokinetics, and Metabolite Profiles of a Single Oral Dose of [14C]INCB099280 in Healthy Male Participants

Healthy Participants

United Kingdom
University of Exeter
The University of Queensland

Completed

Microalgae as an Alternative Protein Source in Human Nutrition. (MAPS)

Nutrition, Healthy

United Kingdom
Imperial College London

Completed

Minimally Invasive Sensing of Beta-lactam Antibiotics (MISBL)

Healthy Volunteers

United Kingdom
King's College London

Completed

The Role of Gut Microbiome on Cardiovascular Health Benefits of Dietary Lignans (CardioFlax Study).

Healthy Volunteers

United Kingdom
University College, London

Completed

Stimulating Compassion UsingTranscutaneous Vagus Nerve Stimulation

Healthy Volunteers

United Kingdom
Biogen

Completed

Study of BIIB091 Formulations in Healthy Participants

Healthy Volunteers

United Kingdom
Genentech, Inc.

Completed

Study to Investigate the Absorption, Metabolism, and Excretion of [14C]-GDC-9545 Following a Single Oral Dose (Part 1) and to Evaluate the Absolute and Relative Bioavailability of Oral Capsule Formulations of GDC-9545 (Part 2) in Healthy Female Subjects of Non-Childbearing Potential

Healthy Volunteers

United Kingdom
Daiichi Sankyo, Inc.
Quotient Sciences

Completed

A Study to Determine the Absolute Oral Bioavailability of Quizartinib Using a Radiolabeled Microtracer in Healthy Subjects

Healthy Subjects

United Kingdom
Ipsen

Completed

A Comparative Study to Evaluate the Effects and Mechanism of Action of Dysport®, Botox® and Xeomin® in the Extensor Digitorum Brevis Model in Healthy Adult Male Participants

Healthy Participants

United Kingdom
AstraZeneca
Parexel

Completed

A Study to Assess the Pharmacokinetics of AZD4831 When Administered Alone and in Combination With Itraconazole

Healthy Volunteers

United Kingdom
H. Lundbeck A/S

Completed

A Study Investigating Lu AG06466 in Healthy Men

Healthy Volunteers

United Kingdom
AstraZeneca

Completed

Study to Assess the Effect of AZD4831 on the Pharmacokinetics (Drug Behavior in the Body) of Midazolam

Healthy Volunteers

United Kingdom
Spero Therapeutics
United States Department of Defense

Completed

Study to Assess the Intrapulmonary Pharmacokinetics of SPR206 in Healthy Volunteers

Healthy Volunteers

United Kingdom
Heptares Therapeutics Limited

Completed

Comparison of Blood Levels of HTL0016878 From an Oral Capsule and an Oral Solution

Healthy Subjects

United Kingdom
GlaxoSmithKline

Completed

Safety, Tolerability, Pharmacokinetics, Pharmacodynamics of GSK2330811 in Healthy Japanese Participants

Healthy Volunteers

United Kingdom
Heptares Therapeutics Limited

Completed

Measurement of HTL0016878 in Cerebrospinal Fluid

Healthy Subjects

United Kingdom
GlaxoSmithKline

Completed

Safety, Tolerability, Pharmacokinetics (PK) and Pharmacodynamics (PD) of GSK2831781 After an Intravenous (IV) Dose in Healthy Japanese and Caucasian Subjects, and a Subcutaneous (SC) Dose in Healthy Caucasian Subjects

Healthy Volunteers

United Kingdom
MedDay Pharmaceuticals SA
Quotient Sciences

Completed

Mass Balance Recovery, Metabolite Profile and Metabolite Identification of [14C]-MD1003 in Healthy Male Subjects

Healthy Volunteers

United Kingdom
Ixchelsis Limited

Completed

Relative Bioavailability and Food Effect Study of IX-01 Capsules in Healthy Men

Healthy Participants

United Kingdom
Affibody
Parexel

Terminated

A Study to Investigate the Safety, Tolerability and Pharmacokinetics of ABY-039

Healthy Volunteers

United Kingdom
AstraZeneca
Quotient Sciences

Completed

AZD4635 Relative Bioavailability Study (Rel Bio)

Healthy Volunteers

United Kingdom
King's College London

Unknown

The Relationship Between Dual-task Gait Performance, Physical Activity Levels, Sleep and Aging in Healthy Adults

Healthy | Adults

United Kingdom
Genentech, Inc.

Completed

Effect of Food, Rabeprazole, Methotrexate and Formulation on the Pharmacokinetics (PK) of GDC-0853 and the Effect of GDC-0853 on the PK of Methotrexate in Healthy Subjects (QCL117578)

Healthy Volunteer

United Kingdom
Celgene

Completed

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single and Multiple Doses of CC-99677 in Healthy Adult Subjects

Healthy Volunteer

United Kingdom
Helsinn Healthcare SA
Quotient Sciences

Completed

A Study In Healthy Male Volunteers Designed To Investigate How A Radiolabelled Medicine Is Broken Down And Removed From The Body

Healthy Subjects

United Kingdom
Imperial College London

Completed

Effect of Broccoli Sprout on Blood Levels of Sulforaphane to Reduce Responsiveness of Immune System

Healthy Volunteers

United Kingdom
Quantum Genomics SA
Quotient Sciences

Completed

Evaluation of the PK Profile of Firibastat Following Administration of Firibastat Prototype Tablet Formulations

Healthy Males

United Kingdom
ORIC Pharmaceuticals

Completed

Single and Multiple Dose Study of ORIC-101 in Adult Healthy Subjects

Healthy Volunteers

United Kingdom
Regeneron Pharmaceuticals

Completed

Study of the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of REGN3918 in Healthy Volunteers

Healthy Volunteers

United Kingdom
Idorsia Pharmaceuticals Ltd.

Terminated

A Study to Evaluate if AC-084 is Safe, Its Fate in the Body as Well as Its Potential Effects on the Body in Healthy Subjects

Healthy Subjects

United Kingdom
Debiopharm International SA

Completed

A Study to Investigate the Effect of Itraconazole on the Pharmacokinetics of Debio 1450 in Healthy Subjects

Healthy Participants

United Kingdom
Egalet Ltd

Completed

Open Label Study to Assess the Pharmacokinetics of Intranasal Ketorolac Tromethamine Following Fluticasone Propionate in Healthy Subjects

Healthy Subjects

United Kingdom
Hoffmann-La Roche

Completed

Basmisanil Positron Emission Tomography Study in Japanese Volunteers

Healthy Volunteer

United Kingdom

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