Clinical Trials on Castleman's Disease

Total 382386 results

EusaPharma (UK) Limited
University of Sheffield (ScHARR); KMC Health Care; Castleman Disease Collaborative...

Not yet recruiting

Producing a Novel Symptom Burden Scale for People Living With Idiopathic Multicentric Castleman Disease (ISBUS)

Idiopathic Multicentric Castleman's Disease
Hoffmann-La Roche

Completed

A Study to Provide RoActemra/Actemra (Tocilzumab) to Patients With Multicentric Castleman's Disease Who Demonstrated Benefit From Previous RoActemra/Actemra Treatment

Castleman's Disease

United States
University of Pennsylvania

Recruiting

Sirolimus in Previously Treated Idiopathic Multicentric Castleman Disease

Castleman Disease | Castleman's Disease, Multicentric

United States
Peking Union Medical College Hospital

Unknown

TCP Regimen in Newly Diagnosed MCD:a Prospective, Single-center, Single-arm, Phase-II Pilot Trial

Multicentric Castleman Disease

China
EusaPharma (UK) Limited

Terminated

Siltuximab In Siltuximab-RElapsed/REfractory Multicentric CAstleman Disease (SISREMCAD)

Idiopathic Multicentric Castleman's Disease

United States
Beijing VDJBio Co., LTD.

Recruiting

A Study of Anti-IL-6R mAb Injection in Patients With iMCD

Idiopathic Multicentric Castleman's Disease

China
Peking Union Medical College Hospital

Recruiting

Zanuburutinib in Relapsed and Refractory iMCD: a Prospective, Single-center, Single-arm Trial (iMCD)

Idiopathic Multicentric Castleman's Disease

China
Peking Union Medical College Hospital

Recruiting

BCD Regimen in Newly Diagnosed Idiopathic Multicentric Castleman's Disease (iMCD)

Idiopathic Multicentric Castleman's Disease

China
Janssen Research & Development, LLC

Completed

A Study to Evaluate the Safety of Long-term Treatment With Siltuximab in Patients With Multicentric Castleman's Disease

Multicentric Castleman's Disease

United States, Canada, France, United Kingdom, China, Germany, Taiwan, Spain, Israel, Korea, Republic of, Singapore, Brazil, Belgium, New Zealand, Norway, Egypt, Hong Kong
Janssen Research & Development, LLC

Completed

A Study to Evaluate the Efficacy and Safety of CNTO328 Plus Best Supportive Care in Multicentric Castleman's Disease

Multicentric Castleman's Disease

United States, Canada, France, United Kingdom, China, Germany, Taiwan, Spain, Belgium, Israel, India, Korea, Republic of, Netherlands, Singapore, Brazil, Russian Federation, New Zealand, Hungary, Norway, Australia, Egypt, Hong Kong, Malaysi...
National Cancer Institute (NCI)

Completed

Tocilizumab for KSHV-Associated Multicentric Castleman Disease

Castleman Disease | Multicentric Castleman Disease | Giant Lymph Node Hyperplasia

United States
National Cancer Institute (NCI)

Withdrawn

Study of Pomalidomide Combined With Modified DA-EPOCH and Rituximab in KSHV-Associated Lymphomas

Primary Effusion Lymphoma | Large Cell Lymphoma Arising in KSHV-associated Multicentric Castleman Disease
University of Washington
Hoffmann-La Roche

Withdrawn

Valganciclovir to Treat HHV-8 Associated Multicentric Castleman's Disease

Giant Lymph Node Hyperplasia
University of Pennsylvania
Castleman Disease Collaborative Network

Completed

Unlock the Cell: Castleman's Disease Flow Cytometry Study

Hyperplasia | Castleman Disease | Castleman's Disease | Giant Lymph Node Hyperplasia | Angiofollicular Lymph Hyperplasia | Angiofollicular Lymphoid Hyperplasia | GLNH

United States
Castleman Disease Collaborative Network

Withdrawn

Castleman Disease Collaborative Network Biobank ("Castlebank")

Hyperplasia | Castleman Disease | Castleman's Disease | Giant Lymph Node Hyperplasia | Angiofollicular Lymph Hyperplasia | Angiofollicular Lymph Node Hyperplasia | Angiofollicular Lymphoid Hyperplasia | GLNH | Giant Lymph Node

United States
Case Comprehensive Cancer Center

Suspended

Molecular Basis of Langerhans and Non-Langerhans Cell Histiocytic Neoplasms and Castleman Disease

Non-Langerhans-Cell Histiocytosis | Langerhans Cell Histiocytosis (LCH) | Castleman's Disease (CD)

United States
University of Pennsylvania
Food and Drug Administration (FDA); EUSA Pharma, Inc.; Castleman Disease Collaborative...

Recruiting

International Registry for Patients With Castleman Disease (ACCELERATE)

Castleman Disease | Castleman's Disease | Giant Lymph Node Hyperplasia | Angiofollicular Lymph Hyperplasia | Angiofollicular Lymph Node Hyperplasia | Angiofollicular Lymphoid Hyperplasia | GLNH | Hyperplasia, Giant Lymph Node | Lymph Node Hyperplasia, Giant

United States
Charles University, Czech Republic

Completed

Unicentric Form of Castleman Disease - Surgery Therapy Benefit

Castleman Disease | Unicentric Castleman Disease | Surgery
French National Agency for Research on AIDS and...
Hoffmann-La Roche

Terminated

Rituximab in the Treatment of HIV Associated Multicentric Castleman Disease Dependent on Chemotherapy

HIV Infections | Giant Lymph Node Hyperplasia
Cylene Pharmaceuticals

Unknown

Dose-escalation Study of Oral CX-4945

Breast Cancer | Multiple Myeloma | Advanced Solid Tumors | Inflammatory Breast Cancer | Castleman's Disease

United States
National Cancer Institute (NCI)

Recruiting

Specimen Collections From Participants With HIV Infection, KSHV Infection, Viral-Related Pre-malignant Lesions and Cancer

HIV | Kaposi's Sarcoma | Primary Effusion Lymphoma | Lymphomas | Multicentric Castleman's Disease

United States
UNC Lineberger Comprehensive Cancer Center
Fogarty International Center of the National Institute of Health

Recruiting

Safety and Efficacy of Rituximab for Treatment of Multicentric Castleman Disease in Malawi

Multicentric Castleman Disease

Malawi
National Cancer Institute (NCI)

Active, not recruiting

Virotherapy and Natural History Study of KHSV-Associated Multricentric Castleman s Disease With Correlates of Disease Activity

HIV | Lymphoproliferative Disorder | Malignancy | HHV-8

United States
National Cancer Institute (NCI)

Not yet recruiting

Phase II Study of Pacritinib in Kaposi Sarcoma Herpesvirus (KSHV)-Associated Multicentric Castleman Disease and KSHV-Associated Inflammatory Cytokine Syndrome (KICS)

KSHV Inflammatory Cytokine Syndrome (KICS) | Kaposi Sarcoma Herpesvirus -Associated Multicentric Castleman Disease

United States
Fred Hutchinson Cancer Center

Terminated

Rituximab Hyaluronidase in Combination With Chemotherapy in Treating Aggressive B-cell Lymphoma in Uganda

Diffuse Large B-Cell Lymphoma | Burkitt Lymphoma | KSHV-associated Multicentric Castleman Disease

Uganda
National Cancer Institute (NCI)

Active, not recruiting

Assessment of Bone Mineral Density in People Living With HIV and KSHV Associated Malignancies: A Retrospective Longitudinal Analysis

Kaposi Sarcoma | Primary Effusion Lymphoma | KSHV Associated Multicentric Castleman Disease | IL-6 Related KSHV Associated Cytokine Syndrome

United States
National Cancer Institute (NCI)

Recruiting

Molecular Characterization of Viral-associated Tumors, Tumors Occurring in the Setting of HIV or Other Immune Disorders and Castleman Disease

Kaposi's Sarcoma | Human Immunodeficiency Virus | Castleman's Disease | Viral-Associated Cancer

United States
National Cancer Institute (NCI)

Recruiting

Natural History of KSHV-Associated Multicentric Castleman s Disease

Multicentric Castleman s Disease

United States
UNC Lineberger Comprehensive Cancer Center

Recruiting

Registry for Adults With Plasma Cell Disorders (PCD's)

Multiple Myeloma | Amyloidosis | Smoldering Multiple Myeloma | Plasma Cell Leukemia | Cryoglobulinemia | Light Chain Deposition Disease | Castleman's Disease | Heavy Chain Deposition Disease | Polyneuropathy Organomegaly Endocrinopathy Monoclonal Gammopathy and Skin Changes

United States
Peking University First Hospital

Recruiting

A Cohort Study of Plasma Cell Disorders (PCDs) in PKUFH

Multiple Myeloma | Amyloidosis | Smoldering Multiple Myeloma | Plasma Cell Leukemia | Cryoglobulinemia | Light Chain Deposition Disease | Castleman's Disease | Heavy Chain Deposition Disease | Polyneuropathy Organomegaly Endocrinopathy Monoclonal Gammopathy and Skin Changes | Monoclonal Gammopathy of Undetermined... and other conditions

China
AIDS Malignancy Consortium
National Cancer Institute (NCI)

Recruiting

Collecting Blood and Tissue Sample Donations for Research for HIV/AIDS-Related Cancers

HIV Infection | Hematopoietic and Lymphoid Cell Neoplasm | Malignant Solid Neoplasm | Lymphoma | Multicentric Castleman Disease | Plasmablastic Lymphoma | Kaposi Sarcoma | Recurrent Lymphoma | Anal Carcinoma | Recurrent Kaposi Sarcoma | Recurrent Plasmablastic Lymphoma | Transplant-Related Kaposi Sarcoma

United States
University of Arkansas
National Cancer Institute (NCI)

Completed

Suramin in Treating Patients With Refractory or Relapsed Multiple Myeloma or Castleman's Disease

Multiple Myeloma and Plasma Cell Neoplasm

United States
Centocor, Inc.

Completed

A Safety and Efficacy Study of CNTO 328 in Patients With B-Cell Non-Hodgkin's Lymphoma, Multiple Myeloma, or Castleman's Disease

Lymphoma, Non-Hodgkin | Multiple Myeloma | Giant Lymph Node Hyperplasia

United States
Fondazione IRCCS Ca' Granda, Ospedale Maggiore...

Recruiting

HHV8 and Solid Organ Transplantation

Castleman Disease | Kaposi Sarcoma | Liver Transplant; Complications | Lung Transplant; Complications | Kidney Transplant; Complications | HHV8 | HHV8 Infection | HHV8-Related Malignant Neoplasm

Italy
Sidney Kimmel Comprehensive Cancer Center at Johns...

Terminated

Nelfinavir for the Treatment of Gammaherpesvirus-Related Tumors

Nasopharyngeal Cancer | Gastric Cancer | Hodgkin Lymphoma | Castleman Disease | Non-Hodgkin Lymphoma | Kaposi Sarcoma | EBV

United States
National Cancer Institute (NCI)

Terminated

Ibrutinib in Treating Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma in Patients With HIV Infection

HIV Infection | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Diffuse Mixed Cell Lymphoma | Recurrent Adult Diffuse Small Cleaved Cell Lymphoma | Recurrent Adult Lymphoblastic Lymphoma | Recurrent Grade 1 Follicular Lymphoma | Recurrent Grade 2 Follicular... and other conditions

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Bevacizumab and Temsirolimus Alone or in Combination With Valproic Acid or Cetuximab in Treating Patients With Advanced or Metastatic Malignancy or Other Benign Disease

Castleman Disease | Lymphangioleiomyomatosis | Digestive System Carcinoma | Malignant Neoplasm | Recurrent Breast Carcinoma | Recurrent Thyroid Gland Carcinoma | Metastatic Urothelial Carcinoma | Malignant Female Reproductive System Neoplasm | Neurofibromatosis Type 2 | Recurrent Adult Soft Tissue Sarcoma and other conditions

United States
Gangnam Severance Hospital

Recruiting

Prevalence of Marginal Ulcer After PPPD and Preventive Effect of Proton Pump Inhibitor in Korea: A Prospective Multicenter Study

Pancretic Dissease (Benign/Malignancy) | BIle Duct Diseae(Benign/Malignancy) | Ampulla of Vater Disease (Benign/Malignancy)

Korea, Republic of
University of Michigan
National Institutes of Health (NIH); National Institute of Dental and Craniofacial...

Completed

The Importance of Periostin in Periodontal Health and Disease

Periodontal Disease | Non-diseased Patients

United States
Yonsei University

Active, not recruiting

Low-Density Lipoprotein Cholesterol-targeting Statin Therapy Versus the Intensity-based Statin Therapy in Patients With Coronary Artery Disease (LODESTAR)

Coronary Artery Diseasse

Korea, Republic of
Eisai Co., Ltd.

Completed

Post-marketing Surveillance of Donepezil Hydrochloride Investigation of the Safety and Effectiveness of Combination Therapy of Donepezil Hydrochloride and Memantine Hydrochloride in Patients With Alzheimer's Disease

Alzheimer's Desease

Japan
First Affiliated Hospital of Wenzhou Medical University

Completed

Tongue Image Database and Diagnostic Model for Digestive Tract Disease Diagnosis

Liver Diseases | Small Bowel Disease | Colorectal Disease | Gastric Diseases | Digestive Tract Diseases

China
Facet Biotech

Completed

A Humanized Anti-Interferon-γ Monoclonal Antibody (HuZAF) for Moderate to Severe Crohn's Disease

Crohn's Disease | Colitis | Digestive System Disease | Gastrointestinal Disease | Intestinal Disease

United States, Canada
Klinikum Westbrandenburg GmbH

Unknown

TOPIT; Trough Level Optimized Pediatric Inflammatory Bowel Disease Therapy: A Multicenter Study Comparing Effectiveness of Trough Level Optimized Infliximab Maintenance Therapy With Standard Dosing Regimen of Pediatric Patients With Crohn's Disease (TOPIT)

Pediatric Crohns Disease
Boston Children's Hospital

Recruiting

Allogeneic Valve Transplantation

Valve Disease, Heart | Valve Heart Disease | Valve Disease, Aortic

United States
McMaster Children's Hospital
St. Justine's Hospital

Completed

PediCRaFT: Pediatric Crohn's Disease Fecal Transplant Trial (PediCRaFT)

Inflammatory Bowel Diseases | Crohn Disease | Colitis | Pediatric Crohns Disease

Canada
First Affiliated Hospital of Harbin Medical University

Unknown

Water Injection Colonoscopy vs Air Insufflation Colonoscopy in Experienced Endoscopists

Colon Disease; | Rectal Disease;

China
Academisch Medisch Centrum - Universiteit van Amsterdam...
Celltrion

Recruiting

inDuctIon tREatment With subCuTaneous Infliximab for Crohn's Disease (DIRECTCD)

Bowel Disease | Inflammatory Disease | Disease Crohn

Netherlands
Medtronic - MITG

Completed

Retrospective Collection of PillCam SB Movies (OCEAN)

Inflammatory Bowel Disease, Crohn Disease

Israel
Hospices Civils de Lyon

Not yet recruiting

Autophagy in Paediatric Crohn's Disease (P-IBDphagy)

Crohn Disease | Pediatric Crohns Disease

France

Clinical Trials on Castleman's Disease

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