Clinical Trials on Central Nervous System Disease

Total 294970 results

National Cancer Institute (NCI)

Not yet recruiting

Study to Determine Possible Effects of Apalutamide on EGFR Expression in Patients With Non-muscle Invasive Bladder Cancer

Non-Muscle Invasive Bladder Urothelial Carcinoma | Recurrent Non-Muscle Invasive Bladder Urothelial Carcinoma

United States
Dana-Farber Cancer Institute

Recruiting

Concurrent Laparoscopic Hysterectomy and Weight Loss Surgery in Obese Patients With Endometrial Carcinoma or Endometrial Intraepithelial Neoplasia

Obesity | Endometrial Carcinoma | Endometrial Cancer Stage I | Endometrial Intraepithelial Neoplasia | EIN

United States
Aesculap AG

Active, not recruiting

Plasmafit® Revision Structan® Hip Endoprosthesis Cup

Arthroplasty Complications | Prosthesis Failure | Osteolysis | Degenerative Osteoarthritis | Rheumatic Arthritis | Fractures, Hip | Instability of Prosthetic Joint | Femoral Head Avascular Necrosis

Germany
APR Applied Pharma Research s.a.

Withdrawn

Inhaled ZYESAMI (Aviptadil Acetate) for Treatment of Severe COVID-19 (AVICOVID-3)

SARS-CoV 2 | COVID | ARDS | Acute Lung Injury/Acute Respiratory Distress Syndrome (ARDS) | Dyspnea | ALI
NICHD Neonatal Research Network
National Center for Research Resources (NCRR)

Completed

Vitamin A Supplementation for Extremely-Low-Birth-Weight Infants (Vitamin A)

Sepsis | Respiratory Distress Syndrome, Newborn | Bronchopulmonary Dysplasia | Respiration, Artificial | Infant, Small for Gestational Age | Infant, Premature | Infant, Low Birth Weight | Infant, Newborn

United States
Xiangya Hospital of Central South University

Completed

Early NCPAP Before Surfactant Treatment in Very Preterm Infants With RDS

Bronchopulmonary Dysplasia | Nasal Continuous Positive Airway Pressure, | Preterm Infants, | Surfactant Treatment, | Respiratory Distress Syndrome,
Hospital Clinic of Barcelona

Not yet recruiting

Intratracheal Budesonide With Surfactant to Prevent Bronchopulmmonary Dysplasia. (BuS)

Bronchopulmonary Dysplasia | Prematurity | Respiratory Distress Syndrome in Premature Infant
NeuroRx, Inc.

Recruiting

Inhaled ZYESAMI™ (Aviptadil Acetate) for the Treatment of Severe COVID-19 (AVICOVID-2)

SARS-CoV 2 | COVID | ARDS | Acute Lung Injury/Acute Respiratory Distress Syndrome (ARDS) | Dyspnea | ALI

United States
Wake Forest University Health Sciences

Completed

Relationship of Pulmonary Contusion to Pulmonary Inflammation and Incidence of Acute Respiratory Distress Syndrome

Respiratory Failure | ARDS | Pulmonary Contusion

United States
Universitair Ziekenhuis Brussel

Recruiting

Prevalence of Anal High-risk Human Papilloma Virus Infection and Abnormal Anal Cytology in Men Who Have Sex With Men Using Pre Exposure Prophylaxis

Human Papilloma Virus

Belgium
Ho Sung Kim

Completed

Response Prediction for Anti-angiogenic Treatment in Recurrent Glioblastoma

Magnetic Resonance Imaging | Adult Glioblastoma | Bevacizimab

Korea, Republic of
Washington University School of Medicine
Patient-Centered Outcomes Research Institute; Pennington Biomedical Research... and other collaborators

Active, not recruiting

Treatment Efforts Addressing Child Weight Management by Unifying Patients, Parents & Providers (TEAM UP)

Overnutrition | Nutrition Disorders | Overweight | Body Weight | Pediatric Obesity | Body Weight Changes | Childhood Obesity | Weight Gain | Adolescent Obesity | Obesity, Childhood | Overweight and Obesity | Overweight or Obesity | Overweight Adolescents

United States
University of Florida
United States Department of Defense

Active, not recruiting

Vaccine Immunotherapy for Recurrent Medulloblastoma and Primitive Neuroectodermal Tumor (Re-MATCH)

Medulloblastoma | Neuroectodermal Tumor

United States
Malmö University
Odontologisk Forskning i Region Skåne (OFRS)

Completed

NOACs in Oral and Maxillofacial Surgery: Impact on Post-operative Complications

Postoperative Complications | Hemorrhage | Anticoagulant-induced Bleeding | Oral Surgical Procedures | Anticoagulants Causing Adverse Effects in Therapeutic Use | Surgery, Oral

Sweden
Dana-Farber Cancer Institute
AstraZeneca

Withdrawn

Olaparib in Unresectable/Metastatic Melanoma With BRCA1/2

Uveal Melanoma | Cutaneous Melanoma | Mucosal Melanoma | Recurrent Metastatic Melanoma

United States
University of Nebraska
National Cancer Institute (NCI)

Active, not recruiting

Geriatric Assessment & Genetic Profiling to Personalize Therapy in Older Adults With Acute Myeloid Leukemia

Secondary Acute Myeloid Leukemia | Therapy-Related Acute Myeloid Leukemia | Adult Acute Myeloid Leukemia

United States
Eastern Cooperative Oncology Group
National Cancer Institute (NCI)

Completed

Octreotide With or Without Prednisone in Treating Patients With Metastatic or Recurrent Thymoma

Thymoma and Thymic Carcinoma

United States, South Africa
Medical College of Wisconsin

Completed

(SBRT) and (ART) for Pulmonary Metastases From Soft Tissue Sarcomas

Stage IV Adult Soft Tissue Sarcoma | Sarcoma,Soft Tissue

United States
San Carlo di Nancy Hospital
Elesta S.R.L.

Completed

Transperineal Laser Ablation vs Transurethral Resection for Benign Prostatic Obstruction: A Randomized Clinical Trial

Benign Prostatic Hyperplasia | Benign Prostatic Hypertrophy | Benign Prostatic Hypertrophy With Outflow Obstruction | Prostate Hyperplasia

Italy
Gustave Roussy, Cancer Campus, Grand Paris
Innovative Therapies For Children with Cancer Consortium

Terminated

Study of Vinblastine in Combination With Nilotinib in Children, Adolescents, and Young Adults (VINILO)

Refractory Low-grade Gliomas | Recurrent Low-grade Gliomas

Austria, Italy, France, Denmark, Netherlands, Spain, Switzerland, United Kingdom
Targovax Oy

Completed

A Pilot Study of Sequential ONCOS-102, an Engineered Oncolytic Adenovirus Expressing GMCSF, and Pembrolizumab in Patients With Advanced or Unresectable Melanoma Progressing After Programmed Cell Death Protein 1 (PD1) Blockade

Advanced or Unresectable Melanoma Progressing After PD1 Blockade

United States, Norway
Seema Nagpal

Completed

BPM31510 in Treating Patients With Recurrent High-Grade Glioma Previously Treated With Bevacizumab

Glioblastoma | Gliosarcoma | Recurrent Glioblastoma | Astrocytoma of Brain

United States
Thomas Jefferson University

Unknown

Prevention of Postoperative Nausea and Vomiting After Bariatric Surgery

Morbid Obesity | Bariatric Surgery Candidate | Postoperative Nausea and Vomiting

United States
Sormland County Council, Sweden
Karolinska Institutet; iCellate Medical

Unknown

Measurement of Circulating Tumor Cells in Prostate Cancer (ICELLATEPC)

Prostatic Neoplasms

Sweden
Eli Lilly and Company

Completed

Study of Ramucirumab or Icrucumab (IMC-18F1) With Docetaxel or Docetaxel Alone as Second-Line Therapy in Participants With Bladder,Urethra, Ureter, or Renal Pelvis Carcinoma

Carcinoma of Urinary Tract | Urethral Carcinoma | Carcinoma of Ureter | Carcinoma of Renal Pelvis

United States, Canada
Fan Ming

Completed

A Phase II Trial of Adjuvant Radiotherapy Combined With Chemotherapy for Patients With High-risk Endometrial Cancer (EC-0701)

Prosthesis Survival

China
Baylor Research Institute

Completed

Uterine Cooling During Cesarean Delivery to Reduce Blood Loss and Incidence of Postpartum Hemorrhage

Postpartum Hemorrhage | Uterine Atony

United States
M.D. Anderson Cancer Center
Merck Sharp & Dohme LLC

Completed

Fosaprepitant in Patients Receiving Ifosfamide-based Regimen

Sarcoma | Chemotherapy-induced Nausea and Vomiting | Effects of Chemotherapy | Adverse Effects of Medical Drugs

United States
Pharmacosmos A/S
BioStata

Completed

Treatment of Women After Severe Postpartum Haemorrhage (PP-02)

Severe Postpartum Haemorrhage

Denmark
Baylor College of Medicine
New Approaches to Neuroblastoma Therapy Consortium

Completed

Zoledronic Acid (ZOMETA) With Cyclophosphamide With Neuroblastoma and Cortical Bone Involvement

NEUROBLASTOMA

United States
Ullevaal University Hospital

Completed

Endometrial Polyps: Pathophysiology and Clinical Consequences

Endometrial Cancer | Endometrial Polyp

Norway
Western Galilee Hospital-Nahariya
Common Sense

Unknown

Bacterial Vaginosis Screening and Treatment to Reduce Infective Complications, Abortion and Preterm Delivery

Premature Birth | Abortion, Spontaneous | Vaginosis, Bacterial

Israel
Introgen Therapeutics
M.D. Anderson Cancer Center

Unknown

Safety and Efficacy Study of INGN 241 Gene Therapy in Patients With In Transit Melanoma

Neoplasm Metastasis | Malignant Melanoma

United States
National Cancer Institute (NCI)

Completed

Pilot Study of a Double Isolation Perfusion Schedule Using Melphalan Alone for Intransit Melanoma or Unresectable Sarcoma of the Extremity

Melanoma | Sarcoma

United States
Mahidol University

Recruiting

ECMO for Critically Ill Patients With Respiratory Failure and/or Circulatory Failure

Severe Acute Respiratory Distress Syndrome | Refractory Hypoxemia

Thailand
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Completed

Octreotide in Preventing Diarrhea in Patients Who Are Undergoing Radiation Therapy to the Pelvis

Sarcoma | Cervical Cancer | Diarrhea | Colorectal Cancer | Ovarian Cancer | Fallopian Tube Cancer | Prostate Cancer | Unspecified Adult Solid Tumor, Protocol Specific | Vulvar Cancer | Endometrial Cancer | Vaginal Cancer
Sheikh Zayed Medical College

Recruiting

Efficacy of Nebulized Lidocaine, Salbutamol, and Beclomethasone Plus Salbutamol in the Covid-19 Patients With ARDS on Non-invasive Ventilation; Randomized Control Trial

COVID-19 Acute Respiratory Distress Syndrome

Pakistan
Mongi Slim Hospital

Not yet recruiting

Macintosh Versus Macgrath for Laryngoscopy in COVID 19 Hypoxemic ICU Patients

COVID-19 Acute Respiratory Distress Syndrome
Peking Union Medical College Hospital

Completed

Single-cell Landscape of BALF in Patients With Severe ARDS and CARDS

Covid19 | ARDS: Acute Respiratory Distress Syndrome

China
Ward Photonics LLC

Terminated

Low-Level Laser Therapy Treatment of Lung Inflammation in Post-COVID-19 Recovery

COVID-19 | Acute Respiratory Distress Syndrome

United States
Fondazione IRCCS Ca' Granda, Ospedale Maggiore...

Completed

Efficacy of Respiratory Physiotherapy on Severe ICU-admitted COVID-19 Patients.

COVID-19 Acute Respiratory Distress Syndrome

Italy
Teodoro Marcianò

Terminated

Risk Factors for COVID-19 Mortality (RF-COVID)

Acute Respiratory Distress Syndrome | COVID-19 Virus Infection | Population at Risk

Italy
Istanbul University - Cerrahpasa (IUC)

Withdrawn

Comparison of Extra Vascular Lung Water Index in Covid-19 ARDS and "Typical"ARDS Patients

Covid19 | Respiratory Distress Syndrome, Adult | Pulmonary Edema | Ventilation Perfusion Mismatch

Turkey
University of Maryland, Baltimore

Withdrawn

Pilot RCT of Therapeutic Hypothermia Plus Neuromuscular Blockade in COVID-19 Patients With ARDS (CHILL-pilot)

Respiratory Distress Syndrome, Adult | Sars-CoV2

United States
National Cancer Institute (NCI)

Active, not recruiting

Endoxifen in Adults With Hormone Receptor Positive Solid Tumors

Hormone Receptor-Positive Breast | Gynecologic | Desmoid | Hormone Receptor-Positive Neoplasms

United States
Duke University

Recruiting

T-Cell Mitochondrial Respiration Response to Ketone Monoester Supplement in Healthy Volunteers and COVID-19

COVID-19 Acute Respiratory Distress Syndrome

United States
Southeast University, China

Recruiting

Prognostic Value of PtcO2 in Patients With COVID-19

COVID-19 Acute Respiratory Distress Syndrome

China
Thiogenesis Therapeutics, Inc.

Not yet recruiting

Study of Cysteamine-pantetheine Disulfide (TTI-0102) in Mild to Moderate COVID-19

COVID-19 | COVID-19 Acute Respiratory Distress Syndrome
dafna yahav

Not yet recruiting

Booster Dose of COVID-19 Vaccine for Kidney Transplant Recipients Without Adequate Humoral Response (WHO)

Immunosuppression | COVID-19 Acute Respiratory Distress Syndrome
Lund University Hospital

Recruiting

Exhaled Breath Particles as a Clinical Indicator for Lung Injury and Acute Respiratory Distress Syndrome (ARDS)

Covid19 | ARDS, Human | ALI

Sweden

Clinical Trials on Central Nervous System Disease

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