Clinical Trials on Central Nervous System Fungal Infections

Total 167030 results

Nantes University Hospital

Terminated

Safety and Efficacity of Corneal Collagen Crosslinking in Infectious Keratitis (Bacterial and Fungal ): Randomized,Controlled, Prospective Study. (CXL) (CXL)

Bacterial Keratitis | Fungal Keratitis

France
Vical

Terminated

VL-2397 Compared to Standard First-Line Treatment for Invasive Aspergillosis (IA) in Adults

Invasive Aspergillosis | Invasive Pulmonary Aspergillosis

United States, Korea, Republic of, Canada, Belgium, France, Germany
Assiut University

Not yet recruiting

Clinical and Laboratory Evaluation of Antifungal Resistance in Tinea Capitis

Fungal Resistance
Sohag University

Not yet recruiting

Role of Imaging in Complications of Sinusitis

Rhinosinusitis Chronic | Rhinosinusitis | Fungal Sinusitis | Rhinosinusitis Acute | Allergic Fungal Rhinosinusitis | Intracranial Extension | Invasive Fungal Sinusitis (Diagnosis)

Egypt
Jian-Xin Zhou

Recruiting

Economic Impact of mNGS on Diagnosis of Post-neurosurgical Central Nervous System Infection (mNGS)

Central Nervous System Infections

China
Shire

Terminated

FST-201 In The Treatment of Acute Fungal Otitis Externa

Acute Fungal Otitis Externa

United States
Pfizer

Completed

A Study of the Efficacy and Safety of Voriconazole for the Treatment of Fungal Infections

Candidiasis | Aspergillosis | Cryptococcosis

Taiwan
Academisch Medisch Centrum - Universiteit van Amsterdam...

Completed

Application of an Electronic Nose in the Early Detection of ASpergillosis (AENEAS)

Pulmonary Invasive Aspergillosis

Netherlands
Pulmocide Ltd

Recruiting

Safety and Efficacy of PC945 (Opelconazole) in Combination With Other Antifungal Therapy for the Treatment of Refractory Invasive Pulmonary Aspergillosis (OPERA-T Study)

Refractory IPA

Spain, United States, Canada, Italy, Austria, France, Israel, United Kingdom, Belgium, Korea, Republic of, Brazil, Germany, Chile, Greece, Taiwan, Argentina, Colombia
Red Cross Hospital, Hangzhou, China
First People's Hospital of Hangzhou; Sir Run Run Shaw Hospital; Zhejiang Provincial... and other collaborators

Unknown

Voriconazole for IPA in Chinese Patients With COPD (VIA-COPD)

COPD | Invasive Pulmonary Aspergillosis

China
European Society for Blood and Marrow Transplantation

Active, not recruiting

Central Nervous System Disorders Following Hematopoietic Stem Cell Transplantation

Central Nervous System Infections | Blood Disease | Infection | Blood Cancer | Central Nervous System Complication | Infectious Disease of Nervous System

Australia, Spain, Italy, Germany, France, Colombia, Hungary, Poland, Russian Federation, Tunisia, Turkey
Fariba Nayeri

Unknown

Rapid Test for Detection of the Focus of Infection in Post Neurosurgical Patients.

Meningitis, Bacterial | Infection, Bacterial | Antibiotic Resistant Infection | Nosocomial Infection | Diagnostic Self Evaluation

Sweden
Azienda Ospedaliera di Padova
Merck Sharp & Dohme LLC

Unknown

Caspofungin as Prophylaxis in High Risk Liver Transplantation Recipients (CPHRLTX)

Mycoses | Fungemia

Italy
Sohag University

Not yet recruiting

The Role of Serum Procalcitonin in Diagnosis and Detection of Outcome of Acute Bacterial Meningitis in Childern

CNS Infection in Children
Shanghai General Hospital, Shanghai Jiao Tong University...

Not yet recruiting

To Evaluate the Efficacy and Safety of Micafungin in Preventing Invasive Mycosis After Liver Transplantation

Liver Transplantation
Merck Sharp & Dohme LLC

Terminated

A Study of the Safety, Tolerance, and Pharmacokinetics of Oral Posaconazole in Immunocompromised Children (P03579)

Fungal Infections
National Institutes of Health Clinical Center (CC)

Completed

Natural History of West Nile Virus Infection

Encephalitis | Myelitis | West Nile Virus

United States
MeMed Diagnostics Ltd.
European Commission

Completed

Prospective Study to Characterize Host-pathogen Related Factors in Hospitalized and ED Patients With LRTI and/or Sepsis (TailoredT)

Sepsis | Bacteremia | LRTI | Fungal Infections | Fever Without Source

Israel
University of California, San Francisco
Dartmouth-Hitchcock Medical Center; Aravind Eye Hospitals, India; That Man May...

Completed

Therapeutic Exploratory Study of Comparing Natamycin and Voriconazole to Treat Fungal Corneal Ulcer (MUTT_TE)

Fungal Keratitis

India
National Institute of Allergy and Infectious Diseases...

Recruiting

Natural History of Individuals With Immune System Problems That Lead to Fungal Infections

Invasive Aspergillosis | Chronic Mucocutaneous Candidiasis | CARD9 | APECED

United States
Pfizer

Terminated

An Evaluation Of The Effectiveness And Safety Of Anidulafungin Compared To Caspofungin For The Treatment Of Serious Fungal Infection Due To Candida In Patients With A Dysfunctional Immune System

Candidiasis | Fungemia | Neutropenia

Poland, Russian Federation, France, Bosnia and Herzegovina, Italy, Slovakia
University of Pittsburgh
Pfizer

Completed

Voriconazole as Prophylaxis for Liver Transplant Recipients

Mycoses | Fungemia

United States
University Hospital, Lille
Pfizer

Not yet recruiting

Incidence of Invasive Pulmonary Aspergillosis in Ventilator-associated Pneumonia (ASPIC)

Ventilator Associated Pneumonia | Pulmonary Aspergillosis Invasive
Changchun Keygen Biological Products Co., Ltd.
Guangdong Provincial Institute of Biological Products And Materia Medica

Completed

Immunogenicity and Safety of Live Attenuated Varicella Vaccine Combined With Live Attenuated JE Vaccine

Japanese Encephalitis | Chickenpox

China
International Maternal Pediatric Adolescent AIDS...
National Institute of Allergy and Infectious Diseases (NIAID); Comprehensive... and other collaborators

Terminated

Daily Isoniazid to Prevent Tuberculosis in Infants Born to Mothers With HIV

HIV Infection | Tuberculosis | Pneumocystis Jiroveci Pneumonia

Botswana, South Africa
Marjan Industria e Comercio ltda

Unknown

Efficacy and Safety Study of Metronidazole, Nystatin and Dexamethasone Combination Therapy in Bacterial and Fungal Vaginal Infections

Bacterial Vaginosis | Fungal Vaginal Infections

Brazil
Accelerate Diagnostics, Inc.

Completed

Clinical Performance of the Accelerate ID/AST System for Positive Blood Culture

Fungemia | Bacteremia

United States
BioWest Therapeutics Inc

Completed

Safety and Efficacy of MBI 226 for the Prevention of Central Venous Catheter-Related Bloodstream Infections

Sepsis | Fungemia | Bacteremia

United States
Pfizer

Completed

Post Marketing Surveillance Study To Observe Safety And Efficacy Of Eraxis® IV

Candidemia | Other Forms of Candida Infections(Intra-abdominal Abscess, Peritonitis)

Korea, Republic of
Instituto do Coracao
Fundação de Amparo à Pesquisa do Estado de São Paulo

Completed

Evaluation in the Treatment of Nosocomial Sepsis Comparing Polymerase Chain Reaction With Conventional Blood Culture.

Sepsis | Fungemia | Bacteremia

Brazil
Singapore General Hospital
Duke-NUS Graduate Medical School

Recruiting

An Experimental Medicine Decipher of a Minimum Correlate of Cellular Immunity

Japanese Encephalitis | Infectious Disease | Yellow Fever | Viral Infection

Singapore
Emory University
Sanofi

Recruiting

Add-on Dupilumab for AFRS as Postoperative Therapy (ADAPT) (ADAPT)

Allergic Fungal Rhinosinusitis

United States
Medical University of Graz
Medical University Innsbruck

Completed

NOBICS - NOvel BIomarker In Invasive CandidiasiS/Candida Sepsis (NOBICS)

Invasive Candidiasis

Austria
Fadoi Foundation, Italy

Terminated

Comparison of Two Diagnostic Tests in Patients With Suspected Invasive Candidiasis in Internal Medicine Wards and Who Are Currently Timely Treated With Micafungin (EPICA1)

Invasive Candidiasis

Italy
Kevin Watt

Completed

Pharmacokinetics of Micafungin in Children on Extracorporeal Membrane Oxygenation

Invasive Candidiasis

United States
Duke University
Pfizer

Completed

β-D-Glucan (BDG) Surveillance With Preemptive Anidulafungin vs. Standard Care for Invasive Candidiasis in Surgical Intensive Care Unit (SICU) Patients

Invasive Candidiasis

United States
University of Pittsburgh
Astellas Pharma US, Inc.

Completed

Pharmacokinetic Profile of Inhaled Liposomal Amphotericin B in Lung Transplant Recipients - Ambisome Study

Lung Transplantation | Fungal Infections

United States
Scynexis, Inc.

Completed

Study to Evaluate the Efficacy and Safety of Ibrexafungerp in Patients With Fungal Diseases That Are Refractory to or Intolerant of Standard Antifungal Treatment (FURI)

Coccidioidomycosis | Invasive Pulmonary Aspergillosis | Allergic Bronchopulmonary Aspergillosis | Histoplasmosis | Chronic Pulmonary Aspergillosis | Blastomycosis | Invasive Candidiasis | Recurrent Vulvovaginal Candidiasis | Mucocutaneous Candidiasis | Other Emerging Fungi

United States, Spain, United Kingdom, Austria, Pakistan, South Africa, Germany, Netherlands
Centre Hospitalier Universitaire, Amiens
University Hospital, Lille; Centre Hospitalier de Lens

Completed

Clinical and Prognostic Comparisons Between Invasive Pulmonary Aspergillosis With or Without Invasive Tracheobronchitis During Severe Influenza: a Retrospective Multicenter Cohort Study. (ITBA)

Morality | Invasive Pulmonary Aspergillosis

France
Medical University of Graz

Completed

Clinical Evaluation of Novel Biomarkers in Patients With Septicemia (NOBIS)

Sepsis | Fungemia | Bacteremia

Austria
University of Southampton
University Hospital Southampton NHS Foundation Trust

Completed

Challenge of the Nasopharynx With Neisseria Lactamica Expressing the Meningococcal Protein Neisseria Adhesin A (NadA) (NadA-Lac4)

Meningitis, Bacterial | Neisseria Infection

United Kingdom
Rambam Health Care Campus

Recruiting

VOC in Breath Samples for the Diagnosis of IPA

Invasive Pulmonary Aspergillosis | Volatile Organic Compounds | Breath Samples

Israel
Assiut University

Not yet recruiting

Sinonasal Risk Factors for Occurrence of Unilateral Versus Bilateral Allergic Fungal Rhinosinusitis .

Allergic Fungal Rhinosinusitis
Sanofi
Regeneron Pharmaceuticals

Active, not recruiting

Dupilumab in Allergic Fungal Rhinosinusitis (AFRS) (LIBERTY-AFRS-AI)

Allergic Fungal Rhinosinusitis

China, Argentina, Israel, United States, Canada, India, Japan, Saudi Arabia, Turkey
Karolinska University Hospital

Completed

Prevalence of Influenza RelAted Invasive Aspergillosis (PIRAIA)

Influenza, Human | Invasive Pulmonary Aspergillosis

Sweden
Inger Lise Gade
Aarhus University Hospital

Completed

Non-invasive Diagnosis of Invasive Pulmonary Aspergillosis by Use of Biomarkers in Exhaled Breath Condensate (NIPA)

Pneumocystis Pneumonia | Aspergillosis Pneumonia

Denmark
Xuanwu Hospital, Beijing

Not yet recruiting

Establishment of Prevention and Control System of Central Nervous System Infection

Encephalitis | Meningitis | Central Nervous System (CNS) Infection

China
Assiut University

Completed

Treatment of Candidal Vulvovaginitis Using Cumin Seed Extract Vaginal Suppositories.

Infection, Fungal

Egypt
Universitätsklinikum Hamburg-Eppendorf

Completed

Diagnosis of Invasive Pulmonary Aspergillosis (IPA) in Critically Ill Patients (DipA)

Survival After IPA | Risk Factors for IPA

Germany
National Institute of Allergy and Infectious Diseases...

Completed

Aerosols in the Treatment of Asymptomatic Pneumocystis Pneumonia: A Pilot Study Assessing the Effectiveness of Aerosolized Pentamidine as Treatment of Subclinical Pneumocystis Infection in Patients With No Clinical Symptoms

HIV Infections | Pneumonia, Pneumocystis Carinii

United States

Clinical Trials on Central Nervous System Fungal Infections

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