Clinical Trials on Checkpoint Kinase 2 Gene Mutation
Total 467 results
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Memorial Sloan Kettering Cancer CenterMerck Sharp & Dohme LLC; Genentech, Inc.RecruitingEsophageal Cancer | Gastric Adenocarcinoma | HER2 Gene MutationUnited States
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University College, LondonNIHR Rare Diseases Translational Research Collaboration; Barts Cardiovascular...RecruitingLamin A/C Gene Mutation | Dilated Cardiomyopathy, FamilialUnited Kingdom
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Massachusetts General HospitalLUNGevity Foundation; Addario Lung Cancer Medical InstituteRecruitingNon-Small Cell Lung Cancer | Anaplastic Lymphoma Kinase Gene TranslocationUnited States
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Masonic Cancer Center, University of MinnesotaRecruitingAcute Myeloid Leukemia | Juvenile Myelomonocytic Leukemia | Acute Lymphoblastic Leukemia | AML | Acute Leukemia | Neurofibromatosis 1 | Hematologic Malignancy | Myelodysplasia | Minimal Residual Disease | Chromosome Abnormality | Monosomy 7 | Remission | Somatic Mutation | Cytogenetic Abnormality | TP53 | Fetal Hemoglobin | Intrachromosomal Amplification of Chromosome... and other conditionsUnited States
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Peking Union Medical College HospitalNot yet recruitingNon Small Cell Lung Cancer | Immune Checkpoint Inhibitor | EGFR Exon 21 MutationChina
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The Fourth Affiliated Hospital of Zhejiang University...CompletedNSCLC | EGFR Gene Mutation | Non-small-lung-cell CancerChina
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Fondazione I.R.C.C.S. Istituto Neurologico Carlo...University of Campania "Luigi Vanvitelli"; IRCCS National Neurological Institute...Active, not recruitingParkinson Disease | GBA Gene MutationItaly
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M.D. Anderson Cancer CenterNational Cancer Institute (NCI)Active, not recruitingObesity | Overweight | Ductal Breast Carcinoma In Situ | Deleterious BRCA1 Gene Mutation | Deleterious BRCA2 Gene Mutation | Premalignant LesionUnited States
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Fudan UniversityNot yet recruitingLung Cancer | Minimal Residual Disease | EGFR Gene Mutation
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Stanford UniversityNot yet recruitingPTEN Gene Mutation | PTEN Hamartoma Tumor Syndrome | PTEN Hamartoma SyndromeUnited States
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David E GerberCancer Prevention Research Institute of Texas; Sagimet Biosciences Inc.Recruiting
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Shanghai Pulmonary Hospital, Shanghai, ChinaCompletedEGFR Gene Mutation | Lung Adenocarcinoma Stage IIIChina
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Chul KimBristol-Myers Squibb; AstraZeneca; Walter Reed National Military Medical Center; Hackensack Meridian HealthActive, not recruitingNonsmall Cell Lung Cancer | EGFR Gene MutationUnited States
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Korean Association for the Study of Targeted TherapyChonnam National University Hospital; Kyungpook National University Hospital; Konkuk University Medical Center and other collaboratorsCompletedHER2 Gene Mutation | Adenocarcinoma Lung Stage IVKorea, Republic of
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M.D. Anderson Cancer CenterNational Cancer Institute (NCI); Spectrum Pharmaceuticals, IncActive, not recruitingEGFR Exon 20 Mutation | ERBB2 Gene Mutation | Recurrent Lung Non-Small Cell Carcinoma | Stage IV Non-Small Cell Lung Cancer AJCC v7United States
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Hunan Province Tumor HospitalRecruitingCarcinoma, Non-Small Cell Lung | EGFR Gene MutationChina
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Yonsei UniversityUnknownElective Surgery of Short Duration (Less Than 2 hr) Undergoing General Anesthesia Using Supraglottic AirwayKorea, Republic of
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Massachusetts General HospitalRecruitingLynch Syndrome | Genetic Predisposition to Disease | Prostate Cancer | BRCA1 Mutation | BRCA2 Mutation | Prostatic Neoplasm | ATM Gene Mutation | MMR MutationUnited States
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Murdoch Childrens Research InstituteRoyal Children's Hospital; Peter MacCallum Cancer Centre, AustraliaNot yet recruitingArteriovenous Malformations | Vascular Malformations | MAP2K1 Gene Mutation | PIK3CA-related Overgrowth Spectrum | Vascular Anomalies | Lymphangioma | Lymphatic Malformation | KRAS G12D | Venous Malformation | Vascular Anomaly | KRAS G12C | PI3K Gene Mutation | Slow-Flow Vascular Malformation | Fast-Flow Vascular... and other conditionsAustralia
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Memorial Sloan Kettering Cancer CenterCompletedOvarian Cancer | Non Small Cell Lung Cancer | RET Gene Mutation | BRAF Gene MutationUnited States
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Ohio State University Comprehensive Cancer CenterCompletedBRCA1 Gene Mutation | BRCA2 Gene Mutation | Ductal Breast Carcinoma in Situ | Atypical Ductal Breast Hyperplasia | Lobular Breast Carcinoma in SituUnited States
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University Hospital, MontpellierHôpital Cochin; Hôpital Necker-Enfants Malades; Foch Hospital, Suresnes, FRANCERecruitingCystic Fibrosis | CFTR Gene MutationFrance
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Li Zhang, MDNot yet recruiting
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Sichuan Cancer Hospital and Research InstituteNot yet recruitingNon-squamous Non-small Cell Lung Cancer | EGFR Gene MutationChina
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Qianqian QuNot yet recruitingMalignant Tumor of the Ovary | XRCC2 Gene Mutation
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Second Affiliated Hospital of Nanchang UniversityNanchang UniversityUnknownNon-small Cell Lung Cancer | EGFR Gene MutationChina
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Karolinska InstitutetCompletedWomen With Mutations in the Breast Cancer Susceptibility Genes BRCA1,2Sweden
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Fundación GECPRecruitingNon Small Cell Lung Cancer | EGFR Gene MutationSpain
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Sun Yat-sen UniversityRecruitingLymphoma, Non-Hodgkin | Pediatric Cancer | Lymphoblastic Lymphoma, Childhood | PTEN Loss | NOTCH1 Gene MutationChina
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Beijing Tiantan HospitalRactigen TherapeuticsEnrolling by invitation
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Academic and Community Cancer Research UnitedNational Cancer Institute (NCI)Active, not recruitingMetastatic Colorectal Adenocarcinoma | Stage IV Colorectal Cancer AJCC v8 | Stage IVA Colorectal Cancer AJCC v8 | Stage IVB Colorectal Cancer AJCC v8 | Stage IVC Colorectal Cancer AJCC v8 | Stage III Colorectal Cancer AJCC v8 | Stage IIIA Colorectal Cancer AJCC v8 | Stage IIIB Colorectal Cancer AJCC... and other conditionsUnited States
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Regeneron PharmaceuticalsRecruitingCongenital Hearing Loss Secondary to Biallelic Mutations of the Otoferlin Gene (OTOF)Spain, United Kingdom, United States
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Changhoon YooCompletedCholangiocarcinoma | Biliary Tract Cancer | HER-2 Gene Amplification | HER-2 Protein OverexpressionKorea, Republic of
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Shanghai Pulmonary Hospital, Shanghai, ChinaRecruitingEGFR Gene Mutation | Lung Adenocarcinoma Stage III | Lung Adenocarcinoma Stage IVChina
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Boston Children's HospitalEunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaboratorsCompletedPTEN Gene Mutation | PTEN Hamartoma Tumor SyndromeUnited States
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The Netherlands Cancer InstituteDaiichi Sankyo, Inc.Not yet recruitingEGFR Gene Mutation | Non-Small Cell Lung Carcinoma | Advanced Non-Small Cell Squamous Lung Cancer
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Jiangsu HengRui Medicine Co., Ltd.Shanghai Chest HospitalUnknownChemotherapy Effect | KRAS Gene Mutation | NSCLC Stage IV | PD-1 Antibody
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Dr Joanne CHIURecruitingALK Gene Rearrangement Positive | EGF-R Positive Non-Small Cell Lung Cancer | EGFR Activating Mutation | Nsclc | ROS1 Gene Rearrangement | ROS1 Positive NSCLC - Reactive Oxygen Species 1 Positive Non-Small Cell Lung CancerHong Kong
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Ohio State University Comprehensive Cancer CenterImmunoGen, Inc.; Clovis Oncology, Inc.Active, not recruitingBRCA1 Gene Mutation | BRCA2 Gene Mutation | Folate Receptor Alpha Positive | Recurrent Fallopian Tube Carcinoma | Recurrent Ovarian Carcinoma | Recurrent Primary Peritoneal Carcinoma | Recurrent Uterine Corpus Carcinoma | Recurrent Uterine Serous Carcinoma | Recurrent Uterine Carcinosarcoma | Platinum...United States
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Vanderbilt University Medical CenterRecruitingIdiopathic Pulmonary Arterial Hypertension | Heritable Pulmonary Arterial Hypertension | Unaffected Mutation Carriers: Healthy Participants With a Known BMPR2 Gene Mutation and Normal Pulmonary Pressure and RV Function on Echo | Healthy Individuals With no Cardiopulmonary DiseaseUnited States
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Guangdong Provincial People's HospitalRecruitingNon Small Cell Lung Cancer | EGFR Gene MutationChina
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University of AarhusRecruitingCystic Fibrosis (CF) | CFTR Gene MutationDenmark
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Pusan National University HospitalRecruitingNon Small Cell Lung Cancer | EGFR Gene MutationKorea, Republic of
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Intergroupe Francophone de Cancerologie ThoraciqueRecruitingNon Small Cell Lung Cancer | ALK Gene MutationFrance
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Dana-Farber Cancer InstituteAbbVie; Pharmacyclics LLC.Active, not recruitingWaldenstrom Macroglobulinemia | MYD88 Gene MutationUnited States
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Memorial Sloan Kettering Cancer CenterCompletedNon Small Cell Lung Cancer | KRAS Gene MutationUnited States
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Children's Healthcare of AtlantaEmory University; Brigham and Women's Hospital; University of California, San... and other collaboratorsWithdrawnPentalogy of Cantrell | Mutations in Non-muscle GenesUnited States
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National Cancer Institute (NCI)CompletedTherapy-Related Acute Myeloid Leukemia | Acute Myeloid Leukemia With FLT3/ITD Mutation | FLT3 Gene Mutation | Acute Promyelocytic Leukemia With PML-RARA | Acute Myeloid Leukemia With Inv(16)(p13.1q22) or t(16;16)(p13.1;q22); CBFB-MYH11 | Acute Myeloid Leukemia With t(8;21); (q22; q22.1); RUNX1-RUNX1T1United States
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Massachusetts General HospitalPfizer; Array BioPharmaRecruitingNSCLC | Lung Cancer | Relapsed Cancer | Resistant Cancer | MET Amplification | Anaplastic Lymphoma Kinase Gene Translocation | ROS1 RearrangementUnited States
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Assistance Publique - Hôpitaux de ParisCentre Leon Berard; Institut National de la Santé Et de la Recherche Médicale... and other collaboratorsNot yet recruitingEnvironmental Exposure | SDH Gene Mutation | SDH-Related Familial Paraganglioma | SDHx-Related SyndromesFrance