Clinical Trials on Chemical and Drug Induced Liver Injury in United Kingdom

Total 5264 results

Wake Forest University Health Sciences
National Cancer Institute (NCI)

Completed

Donepezil in Treating Young Patients With Primary Brain Tumors Previously Treated With Radiation Therapy to the Brain

Brain and Central Nervous System Tumors | Neurotoxicity | Radiation Toxicity | Cognitive/Functional Effects | Long-term Effects Secondary to Cancer Therapy in Children | Psychosocial Effects of Cancer and Its Treatment

United States
RAND
National Institute of Mental Health (NIMH); University of Pittsburgh; Boston... and other collaborators

Active, not recruiting

Competitive Revision for CLARO: Collaboration Leading to Addiction Treatment and Recovery From Other Stresses

Depression | Suicidal Ideation | Addiction | Post Traumatic Stress Disorder | Opioid-use Disorder

United States
MD Stem Cells

Enrolling by invitation

Alzheimer's Autism and Cognitive Impairment Stem Cell Treatment Study (ACIST)

Alzheimer Disease | Traumatic Brain Injury | Autism Spectrum Disorder | Lewy Body Disease | Vascular Dementia | Autism | Dementia, Mixed | Alzheimer Dementia | Dementia, Multi-Infarct | Cadasil | Parkinson-Dementia Syndrome | Chronic Traumatic Encephalopathy | Autistic Behavior | Lewy Body Dementia With Behavioral... and other conditions

United States, United Arab Emirates
University of Washington
National Institute on Drug Abuse (NIDA)

Recruiting

Combination Primary Care and Prevention Services for Women Who Inject Drugs and Exchange Sex in Seattle, Washington

HIV Infections | Opioid Use Disorder | Chlamydia | Gonorrhea | Syphilis | Trichomonas

United States
Yale University
National Institute of Mental Health (NIMH)

Not yet recruiting

The Dreamer Girls Project: Adaptation of SISTA/SIHLE for HIV/AIDS and Substance Abuse Prevention Among Black Adolescent Girls

HIV/AIDS

United States
Eastern Cooperative Oncology Group
National Cancer Institute (NCI)

Active, not recruiting

Rituximab, Bendamustine Hydrochloride, and Bortezomib Followed by Rituximab and Lenalidomide in Treating Older Patients With Previously Untreated Mantle Cell Lymphoma

Lymphoma | Neurotoxicity | Therapy-related Toxicity

United States, Canada
Massachusetts General Hospital

Recruiting

Treatment of Restless Legs Symptoms With Pramipexole to Improve the Outcomes of Protracted Opioid Withdrawal in OUD

Sleep Disorder | Restless Legs Syndrome | Opioid-use Disorder | Opioid Withdrawal

United States
Brown University
National Institute on Drug Abuse (NIDA); University of California, San Diego; Beth Israel Deaconess Medical Center and other collaborators

Recruiting

Pre-exposure Prophylaxis (PrEP) for Health (PrEP)

Substance Dependence | HIV (Human Immunodeficiency Virus)

United States
Yale University
National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Completed

Alcohol Pharmacotherapy for HIV+ Prisoners (INSPIRE)

Alcohol Dependence | Human Immunodeficiency Virus | AIDS | Hazardous Drinking | Problem Drinking

United States
University of Pittsburgh
UPMC Center for High-Value Health Care; Western Psychiatric Institute and Clinic... and other collaborators

Completed

Optimizing Behavioral Health Homes for Adults With Serious Mental Illness (PCORI OH)

Vascular Diseases | Cardiovascular Disease | Chronic Disease | Diabetes Mellitus Type 2 | Mental Health | Substance-related Disorders | Behavioral Health

United States
Progenity, Inc.

Completed

Collection of Samples From Pregnant Women for the Evaluation of Preeclampsia (Pre-E) Biomarkers

Hypertension | Renal Insufficiency | Proteinuria | Thrombocytopenia | Preeclampsia | Pulmonary Edema | Impaired Liver Function

United States
Roswell Park Cancer Institute
National Cancer Institute (NCI)

Completed

Dimesna in Treating Patients With Solid Tumors Who Are Undergoing Treatment With Cisplatin and Paclitaxel

Head and Neck Cancer | Ovarian Cancer | Lung Cancer | Neurotoxicity

United States
Fox Chase Cancer Center
National Cancer Institute (NCI)

Completed

Heavy Metal Exposure in Predicting Peripheral Neuropathy in Patients With Stage I-III Breast Cancer Undergoing Chemotherapy

Neurotoxicity | Peripheral Neuropathy | Male Breast Cancer | Stage II Breast Cancer | Stage IIIA Breast Cancer | Stage IIIB Breast Cancer | Stage IA Breast Cancer | Stage IB Breast Cancer | Stage IIIC Breast Cancer

United States
University of Houston
National Institute on Drug Abuse (NIDA)

Completed

Project PRIDE (Promoting Resilience In Discriminatory Environments)

Depression | Anxiety | Substance Use Disorders | Sexually Transmitted Infections | Human Immunodeficiency Virus

United States
Yale University
National Institute on Drug Abuse (NIDA); National Institute of Mental Health...

Recruiting

Imaging Cannabinoid Receptors Using Positron Emission Tomography (PET) Scanning

Schizophrenia | Post Traumatic Stress Disorder | Cannabis Dependence | Opioid-use Disorder | Healthy Control | Prodromal for Psychotic Illness | Family History of Alcoholism

United States
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Completed

Memantine Hydrochloride in Helping Cancer Survivors Stop Smoking

Breast Cancer | Colorectal Cancer | Tobacco Use Disorder | Lung Cancer | Prostate Cancer

United States
Rhode Island Hospital

Recruiting

Combined Injectable Treatment for HIV and OUD (CHOICE)

Opioid Use Disorder | Human Immunodeficiency Virus

United States
University of New Hampshire
National Institute on Alcohol Abuse and Alcoholism (NIAAA); University of South... and other collaborators

Completed

Development and Pilot Trial of an Intervention to Reduce Disclosure Recipients Negative Social Reactions and Victims Psychological Distress and Problem Drinking

Depression | Alcohol Drinking | Alcohol; Harmful Use | Social Skills | Coping Behavior | Post-traumatic Stress Disorder | Coping Skills | Social Behavior | Alcohol Abuse | Drinking, College | Social Stigma | Empathy | Self-Criticism | Social Norms | Social Responsibility

United States
University of Texas at Austin
Way West Wellness; SunFlora.Inc

Suspended

CBD Oil for Reducing Emotional Impact of COVID-19 (CBDOIL)

Anger | Sleep Disturbance | Anxiety Depression | Substance Abuse | Alcohol Abuse | Stress Reaction

United States
Columbia University

Completed

Glutamine in Treating Neuropathy Caused by Vincristine in Young Patients With Lymphoma, Leukemia, or Solid Tumors

Sarcoma | Lymphoma | Kidney Cancer | Leukemia | Neurotoxicity | Peripheral Neuropathy

United States
Jack Khouri

Not yet recruiting

Siltuximab for Cytokine Release Syndrome Prophylaxis Prior to tx w/ Teclistamab in RRMM

Multiple Myeloma | Refractory Multiple Myeloma | Cytokine Release Syndrome | Immune Effector Cell Associated Neurotoxicity Syndrome

United States
Rush University Medical Center

Recruiting

Gut Microbiota-Mediated Inflammatory Interactions Between AUD and HIV Infection

Alcohol Use Disorder | Human Immunodeficiency Virus

United States
University of Pittsburgh
Indiana University of Pennsylvania

Completed

The Effect of Self-Forgiveness on Self-Stigma in Addiction.

Substance Use Disorders | Benzodiazepine Dependence | Alcohol Use Disorder | Substance Abuse | Opioid-use Disorder | Cocaine Use Disorder | Alcohol Abuse | Opiate Dependence | Alcohol Withdrawal | Benzodiazepine Abuse | Cocaine Abuse | Heroin Abuse | Cocaine Withdrawal | Opiate Withdrawal Syndrome | Heroin Overdoses | Heroin...

United States
Mayo Clinic

Not yet recruiting

A Study of the Effect of a Nurse Navigator Program on High Risk Patients

Heart Failure | Alcoholism | Renal Insufficiency | Pulmonary Disease, Chronic Obstructive | Arthroplasty, Replacement, Knee | Arthroplasty, Replacement, Hip | Body Mass Index | Patient Readmission

United States
University of Miami

Completed

Trauma Intervention for Affect Regulation, AIDS, and Substances (TIARAS)

Post Traumatic Stress Disorder | Human Immunodeficiency Virus | Substance Related Disorder

United States
Gynecologic Oncology Group
National Cancer Institute (NCI)

Completed

Amifostine in Treating Peripheral Neuropathy in Patients Who Have Received Chemotherapy for Cancer

Unspecified Adult Solid Tumor, Protocol Specific | Gestational Trophoblastic Tumor | Neurotoxicity | Peripheral Neuropathy

United States
Indiana University
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Recruiting

STTEPP: Safety, Tolerability and Dose Limiting Toxicity of Lacosamide in Patients With Painful Chronic Pancreatitis (STTEPP)

Chronic Pain | Opioid-Related Disorders | Opioid Use Disorder | Opioid Dependence | Chronic Pancreatitis | Hyperalgesia | Chronic Pain Syndrome | ERCP | Pancreatic Surgery | Chronic Abdominal Pain

United States
University of Alabama at Birmingham

Recruiting

Study to Evaluate the Role of Siltuximab in Treatment of Cytokine Release Syndrome (CRS) and Immune Effector Cell Associated Neurotoxicity (ICANS) Related to CAR-T Cell Therapy

Lymphoma, Non-Hodgkin | Multiple Myeloma | Acute Lymphoblastic Leukemia | Cytokine Release Syndrome | ICANS

United States
Georgetown University
Albert Einstein College of Medicine; University of Michigan

Completed

Positively Smoke Free on the Web (PSFW) for Smokers Living With HIV (PSFW)

Tobacco Cessation | Tobacco Use Disorder | Tobacco Use Cessation | Tobacco Dependence | Virus, Human Immunodeficiency | Tobacco-Use Disorder

United States
University of Washington

Active, not recruiting

Facilitating Communication Study (FCS2)

Liver Cirrhosis | Cerebrovascular Disorders | Lung Diseases | Brain Injuries | Neoplasm Metastasis | Pulmonary Disease, Chronic Obstructive | Kidney Failure, Chronic | Chronic Disease | Multiple Organ Failure | Heart Failure, Congestive | Lung Neoplasm | Intensive Care Units | Health Care Quality, Access, and Evaluation and other conditions

United States
VA Office of Research and Development

Recruiting

OSA PAP Treatment for Veterans With SUD and PTSD on Residential Treatment Unit

Obstructive Sleep Apnea | Substance Use Disorder | Post Traumatic Stress Disorder | Residential Treatment Program

United States
Eastern Cooperative Oncology Group
National Cancer Institute (NCI)

Active, not recruiting

Radiation Therapy With or Without Temozolomide in Treating Patients With Low-Grade Glioma

Brain and Central Nervous System Tumors | Neurotoxicity

United States
Massachusetts General Hospital
Baylor College of Medicine; University of Houston; University of Texas at Austin and other collaborators

Recruiting

Effectiveness of an Integrated Treatment to Address Smoking Cessation and Anxiety/ Depression in People Living With HIV

Depression | Smoking | Smoking Cessation | Anxiety | Nicotine Dependence | Human Immunodeficiency Virus | Smoking, Cigarette

United States
University of South Florida
National Cancer Institute (NCI)

Completed

Modafinil in Treating Children With Memory and Attention Problems Caused by Cancer Treatment for a Brain Tumor

Fatigue | Brain and Central Nervous System Tumors | Neurotoxicity | Cognitive/Functional Effects | Psychosocial Effects of Cancer and Its Treatment

United States
University of South Florida
National Cancer Institute (NCI); Children's Oncology Group

Completed

Glutamic Acid in Reducing Nerve Damage Caused by Vincristine in Young Patients With Cancer

Sarcoma | Lymphoma | Kidney Cancer | Leukemia | Neurotoxicity | Peripheral Neuropathy

United States
National Institute of Diabetes and Digestive and...
Massachusetts General Hospital; University of Pennsylvania; Yale University; New... and other collaborators

Active, not recruiting

HOPE Consortium Trial to Reduce Pain and Opioid Use in Hemodialysis (HOPE)

Chronic Pain | End Stage Renal Disease | Opioid Dependence

United States
University of Washington
National Institute on Aging (NIA)

Active, not recruiting

Project to Improve Communication About Serious Illness--Hospital Study: Comparative Effectiveness Trial (Trial 2) (PICSI-H)

Liver Cirrhosis | Quality of Life | Lung Neoplasms | Neoplasm Metastasis | Pulmonary Disease, Chronic Obstructive | Dementia | Kidney Failure, Chronic | Chronic Disease | Peripheral Vascular Disease | Lung Diseases, Interstitial | Health Communication | Heart Failure，Congestive | Patient Care | Health Care Quality... and other conditions

United States
University of Washington
National Institute on Aging (NIA)

Completed

Project to Improve Communication About Serious Illness--Hospital Study: Pragmatic Trial (Trial 1) (PICSI-H)

Liver Cirrhosis | Neoplasm Metastasis | Pulmonary Disease, Chronic Obstructive | Dementia | Kidney Failure, Chronic | Chronic Disease | Peripheral Vascular Disease | Lung Diseases, Interstitial | Health Communication | Lung Neoplasm | Heart Failure，Congestive | Patient Care | Health Care Quality, Access, and Evaluation and other conditions

United States
Children's Oncology Group
National Cancer Institute (NCI)

Completed

Neurobehavioral Complications in Children Who Were Previously Treated With Steroids and Intrathecal Therapy for Acute Lymphoblastic Leukemia

Leukemia | Neurotoxicity | Long-term Effects Secondary to Cancer Therapy in Children | Psychosocial Effects of Cancer and Its Treatment

United States
Progenity, Inc.

Unknown

Collection of Whole Blood Samples for the Evaluation of Preeclampsia (Pre-E) Biomarkers From Pregnant Women

Hypertension | Renal Insufficiency | Thrombocytopenia | Headache | Pre-Eclampsia | Pulmonary Edema | Visual Impairment | Impaired Liver Function | Proteinuria in Pregnancy

United States
VA Office of Research and Development
University of Pennsylvania; Walter Reed National Military Medical Center; Brooke...

Completed

Regional Anesthesia Military Battlefield Pain Outcomes Study (RAMBPOS)

Anxiety Disorders | Substance Abuse | Post-Traumatic Stress Disorder | Depressive Disorders | Complex Regional Pain Syndrome Type II

United States
University of California, San Francisco

Completed

Combination Chemotherapy in Treating Patients With Metastatic Ovarian Cancer or Non-small Cell Lung Cancer

Ovarian Cancer | Lung Cancer | Neurotoxicity

United States
Gynecologic Oncology Group
National Cancer Institute (NCI)

Terminated

Amifostine in Treating Women With Ovarian, Peritoneal, Cervical, Fallopian Tube, Uterine, or Endometrial Cancer

Sarcoma | Cervical Cancer | Ovarian Cancer | Fallopian Tube Cancer | Endometrial Cancer | Neurotoxicity | Primary Peritoneal Cavity Cancer

United States
Massachusetts Eye and Ear Infirmary

Recruiting

Clinical Validation of DystoniaNet Deep Learning Platform for Diagnosis of Isolated Dystonia

Parkinson Disease | Dyskinesias | Temporomandibular Joint Disorders | Dystonia | Torticollis | Essential Tremor | Tic Disorders | Dysphonia | Myoclonus | Ulnar Nerve Entrapment | Drug Induced Dystonia

United States
Gynecologic Oncology Group
National Cancer Institute (NCI)

Unknown

Pelvic Radiation Therapy or Vaginal Implant Radiation Therapy, Paclitaxel, and Carboplatin in Treating Patients With High-Risk Stage I or Stage II Endometrial Cancer

Obesity | Fatigue | Stage I Uterine Corpus Cancer AJCC v7 | Stage II Uterine Corpus Cancer AJCC v7 | Endometrial Clear Cell Adenocarcinoma | Endometrial Serous Adenocarcinoma | Neurotoxicity Syndrome

United States, Korea, Republic of
University of Vermont
University of Massachusetts, Worcester; Arizona State University; Case Western... and other collaborators

Active, not recruiting

Integrating Behavioral Health and Primary Care for Comorbid Behavioral and Medical Problems (IBHPC)

Depression | Heart Failure | Hypertension | Diabetes | Arthritis | Chronic Pain | Irritable Bowel Syndrome | Insomnia | Asthma | Fibromyalgia | Anxiety | Substance Use Disorder | Chronic Obstructive Lung Disease | Problem Drinking

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Amifostine in Treating Peripheral Neuropathy Caused by Paclitaxel in Patients With Solid Tumors

Breast Cancer | Ovarian Cancer | Lung Cancer | Prostate Cancer | Unspecified Adult Solid Tumor, Protocol Specific | Neurotoxicity

United States
Roswell Park Cancer Institute
National Cancer Institute (NCI)

Terminated

Nintedanib Compared With Placebo in Treating Against Radiation-Induced Pneumonitis in Patients With Non-small Cell Lung Cancer That Cannot Be Removed by Surgery and Are Undergoing Chemoradiation Therapy

Lung Non-Squamous Non-Small Cell Carcinoma | Stage II Lung Non-Small Cell Cancer AJCC v7 | Stage IIA Lung Non-Small Cell Carcinoma AJCC v7 | Stage IIB Lung Non-Small Cell Carcinoma AJCC v7 | Stage IIIA Lung Non-Small Cell Cancer AJCC v7 | Stage IIIB Lung Non-Small Cell Cancer AJCC v7 | Stage IV... and other conditions

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Widefield Fluorescence and Reflectance Imaging Systems and Oral Tissue Samples in Monitoring Participants at Risk for Developing Oral Cancer

Tobacco Use Disorder | Fanconi Anemia | Lichen Planus | Oral Neoplasm | Erythroplakia | Premalignant Lesion | Oral Cavity and Lip Precancerous Condition | Oral Cavity Leukoplakia

United States
University of Colorado, Denver
National Institute on Aging (NIA)

Completed

Advancing Understanding of Transportation Options (AUTO)

Stroke | Multiple Sclerosis | Glaucoma | Brain Injuries | Macular Degeneration | Arthritis | Chronic Obstructive Pulmonary Disease | Parkinson Disease | Restless Legs Syndrome | Diabetic Retinopathy | Insomnia | Retinitis Pigmentosa | Obstructive Sleep Apnea | Dementia | End Stage Renal Disease | Sleep Apnea | Syncope | Seizures and other conditions

United States

Clinical Trials on Chemical and Drug Induced Liver Injury in United Kingdom

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Mauritius

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations