Clinical Trials on Chronic HIV Infections in United Kingdom

Total 33779 results

NEAT ID Foundation
PENTA Foundation; European Commission; VERDI Consortium

Recruiting

Morbidity, Mortality And Risk Factors of Mpox in HIV Negative High Risk Sexual Health Clinic Attenders and People Living With HIV (MASH 1)

Monkeypox | HIV Coinfection

Spain, France, Poland, United Kingdom
King's College London
Guy's and St Thomas' NHS Foundation Trust

Completed

Cardiovascular Risk Evaluation and Antiretrovirals in HIV (CREATE1)

HIV Infections | Cardiovascular Risk

United Kingdom
Gilead Sciences

Completed

Efficacy and Safety of Sofosbuvir/Velpatasvir Fixed Dose Combination for 12 Weeks in Adults With Chronic Hepatitis C Virus (HCV) and Human Immunodeficiency Virus (HIV)-1 Coinfection (ASTRAL-5)

Hepatitis C Virus Infection

United States
National Institute of Allergy and Infectious Diseases...

Completed

A Study of Zidovudine Plus Acyclovir in HIV-Infected Patients

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...

Completed

Studies of HIV-1 Infection in Newly Infected Individuals in Southern Africa

HIV Infections | HIV Seronegativity

United States
Gilead Sciences

Completed

Efficacy, Safety, and Tolerability of Ledipasvir/Sofosbuvir (LDV/SOF) Treatment for HIV/HCV Co-infected Participants Who Switch to Elvitegravir/Cobicistat/Emtricitabine/Tenofovir Alafenamide (E/C/F/TAF) or Emtricitabine/Rilpivirine/Tenofovir Alafenamide (F/R/TAF) Prior to LDV/SOF HCV Treatment (Co-STARs)

HIV-1 Infection | HCV Infection

United States, Puerto Rico
Enanta Pharmaceuticals, Inc
hVIVO Services Limited

Recruiting

A Controlled Phase 2a Study to Evaluate the Efficacy of EDP-323 Against Respiratory Syncytial Virus Infection in a Virus Challenge Model

RSV Infection

United Kingdom
Imperial College London

Unknown

Physiology and Structure of the Small Airways in Patients With Chronic Airflow Obstruction or COVID-19 (PASSPORT)

COVID-19 | Asthma | Copd | Small Airways Disease

United Kingdom
St Stephens Aids Trust

Unknown

Targeted Clinical Strategies and Low Level Viraemia (LLV) in Boosted Protease Inhibitor Therapy

HIV

United Kingdom
Tulane University

Recruiting

Tulane Abdominal Transplant Institute (TATI) of Solid Organ Transplantation of HIV-Positive Recipients From HIV-Positive Donors

End Stage Renal Disease | Human Immunodeficiency Virus

United States
Luis Montaner
National Institute of Allergy and Infectious Diseases (NIAID); University of... and other collaborators

Unknown

Peg-Interferon Alpha 2b Combined With Two Intravenous Broadly HIV-1 Neutralizing Antibodies 3BNC117 and 10-1074 (BEAT-2) (BEAT-2)

HIV/AIDS | HIV | HIV-1 Infection

United States
Presidio Pharmaceuticals, Inc.

Completed

A Phase 1b Study of PPI-461 in Patients With HCV Genotype 1

Chronic Genotype 1 Hepatitis C Virus Infection

United Kingdom, Denmark, United States
Enanta Pharmaceuticals, Inc
hVIVO Services Limited

Completed

A Phase 2a Study to Evaluate EDP-938 in the Virus Challenge Model

RSV Infection

United Kingdom
Hvivo
GlaxoSmithKline

Completed

RSV Study in Adults 60 to 75 Years of Age

RSV Infection

United Kingdom
National Institute of Allergy and Infectious Diseases...

Withdrawn

Evaluation of Specific Infection-Fighting Cells For Prediction of Immune Response to Anti-HIV and Immune-Boosting Medication

HIV Infections

United States
Presidio Pharmaceuticals, Inc.

Completed

A Phase 1a/1b Study of PPI-383 in Healthy Adults and Hepatitis C Patients

Hepatitis C, Chronic

United Kingdom, Mauritius
Imperial College London

Recruiting

The Impact of Age on Adaptive Immunity in Adults Infected With Respiratory Syncytial Virus (INFLAMMAGE)

RSV Infection

United Kingdom
Bavarian Nordic

Completed

Phase 2a Study of MVA-BN-RSV Vaccination and RSV Challenge in Healthy Adults

RSV Infection

United Kingdom
Meissa Vaccines, Inc.
Hvivo

Completed

Human Challenge Study to Evaluate the Efficacy of MV-012-968 Vaccine

RSV Infection

United Kingdom
Alios Biopharma Inc.

Completed

A Phase 2a Study to Evaluate ALS-008176 in the Virus Challenge Model

Respiratory Syncytial Virus Infections

United Kingdom
National Institute of Allergy and Infectious Diseases...
HIV Vaccine Trials Network

Completed

Safety of and Immune Response to a DNA HIV Vaccine Followed By Boosting With One of Two Serotypes of Adenoviral Vector HIV Vaccine in Healthy Adults

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...

Withdrawn

A Study of Patients Who Recently Have Been Infected With HIV

HIV Infections

United States
MacroGenics
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

MGD014 in HIV-Infected Individuals on Suppressive Antiretroviral Therapy

HIV-1-infection

United States
University of North Carolina, Chapel Hill
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Study to Assess Safety and Activity of Combination Therapy of VRC07-523LS and Vorinostat on HIV-infected Persons

HIV-1 Infection

United States
University of North Carolina, Chapel Hill
National Institute of Allergy and Infectious Diseases (NIAID); Merck Sharp... and other collaborators

Completed

The Effect of Vorinostat on HIV RNA Expression in the Resting CD4+ T Cells of HIV+ Pts on Stable ART

HIV-1 Infection

United States
Ardea Biosciences, Inc.

Completed

Naïve HIV POC Monotherapy Trial

HIV Infections

Germany, United Kingdom
Merck Sharp & Dohme LLC
Agouron Pharmaceuticals

Completed

A Study on the Safety and Effectiveness of Twice-Daily Nelfinavir Plus Twice-Daily Indinavir Plus Efavirenz in HIV-Positive Patients Who Have Never Taken Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTIs) or Protease Inhibitors

HIV Infections

United States
Kirby Institute

Completed

Pharmacokinetics of Lopinavir/Ritonavir at Three Different Doses. (ENCORE3)

Acquired Immunodeficiency Syndrome

United Kingdom
International AIDS Vaccine Initiative
University of Nairobi; Medical Research Council-Oxford

Completed

A Phase IIA Trial to Evaluate the Safety and Immunogenicity of a DNA HIV-1 Vaccine Followed by an MVA HIV-1 Vaccine in HIV-uninfected Volunteers

HIV Infections

United Kingdom, Kenya
St Stephens Aids Trust

Terminated

Pre-Exposure Prophylaxis Using TMC278LA

HIV Infections

United Kingdom
Bristol-Myers Squibb
Boehringer Ingelheim; Triangle Pharmaceuticals

Terminated

The Safety and Effectiveness of Didanosine Plus Stavudine Plus Nevirapine Combined With MKC-442 in HIV-Infected Patients Who Have Not Had Success With Protease Inhibitors

HIV Infections

United States
Gilead Sciences
Glaxo Wellcome; Dupont Applied Biosciences

Completed

Safety and Effectiveness of Giving Adefovir Dipivoxil Plus Abacavir Plus Efavirenz Plus Amprenavir to HIV-Infected Patients Who Have Failed to Respond to Previous Protease Inhibitor Treatment

HIV Infections

United States
Gilead Sciences
Bristol-Myers Squibb; Glaxo Wellcome; Dupont Applied Biosciences

Completed

Safety and Effectiveness of Giving an Anti-HIV Drug Combination of Adefovir Dipivoxil Plus Didanosine Plus Efavirenz Plus Lamivudine Once Daily to HIV-Infected Patients

HIV Infections

United States
PENTA Foundation
Institut National de la Santé Et de la Recherche Médicale, France; MRC CTU... and other collaborators

Completed

Strategy for Maintenance of HIV Suppression With Once Daily Integrate Inhibitor+Darunavir/Ritonavir in Children (SMILE)

HIV Infection

United Kingdom, Spain, Argentina, France, Mexico, Portugal, South Africa, Switzerland, Thailand, Uganda, Ukraine
University of North Carolina, Chapel Hill
National Institute of Allergy and Infectious Diseases (NIAID)

Completed

Study to Assess Safety and Ability to Induce Immune Responses of HIV-1 Vaccines M3 and M4 Given Alone or in Combination in HIV-infected Adults (M&M)

HIV-1 Infection

United States
Rockefeller University

Completed

Phase I/II, Open-Label Trial of Three Monoclonal Antibodies

HIV Infections

United States
Gilead Sciences

Active, not recruiting

Study to Evaluate the Safety and Efficacy of Emtricitabine and Tenofovir Alafenamide (F/TAF) Fixed-Dose Combination Once Daily for Pre-Exposure Prophylaxis in Men and Transgender Women Who Have Sex With Men and Are At Risk of HIV-1 Infection (DISCOVER)

Pre-Exposure Prophylaxis of HIV-1 Infection

United States, Austria, Denmark, United Kingdom, Netherlands, Italy, Germany, Canada, Ireland, France, Spain
Royal Brompton & Harefield NHS Foundation Trust

Recruiting

Studying the Airway Microenvironment in Patients Undergoing Surgical and Bronchoscopic Interventions for COPD (COPD-ENVIRON)

Chronic Obstructive Pulmonary Disease | Emphysema | Chronic Bronchitis

United Kingdom
Vir Biotechnology, Inc.

Recruiting

Study of VIR-2218, VIR-3434, and/or PEG-IFNα in Subjects With Chronic Hepatitis B Virus Infection (MARCH)

Hepatitis B, Chronic

Hong Kong, Korea, Republic of, Malaysia, New Zealand, Taiwan, United Kingdom, Romania, United States, Moldova, Republic of, Canada, Germany, Ukraine
National Institute of Allergy and Infectious Diseases...
The Immune Response Corporation

Terminated

Effectiveness of Adding Remune to Your Current Anti-HIV Drug Combination

HIV Infections

United States
National Institute of Allergy and Infectious Diseases...

Completed

Lamivudine and Adefovir to Treat Chronic Hepatitis B Infection in People With and Without HIV Infection

HIV Infections | Chronic Hepatitis B

United States
Royal Free Hampstead NHS Trust
Bristol-Myers Squibb; Sigma-Tau Research, Inc.

Unknown

ALCAR Prophylaxis Study

HIV Infections | Distal Symmetric Polyneuropathy

United Kingdom
Hoffmann-La Roche

Completed

A Study of Saquinavir Soft Gelatin Capsules Combined With Other Anti-HIV Drugs in HIV-1 Infected Patients

HIV Infections

United States
Novartis Pharmaceuticals

Completed

Pharmacokinetics and Safety of Single-Dose Telbivudine in Children and Adolescents With Chronic Hepatitis B

Chronic Hepatitis B

Belgium, Germany, United Kingdom, Philippines
Chelsea and Westminster NHS Foundation Trust
Merck Sharp & Dohme LLC; Imperial College London; University of Liverpool

Completed

Pharmacokinetics of Plasma Doravirine Once Daily Over 72 Hours Following Drug Intake Cessation in Healthy Volunteers

Human Immunodeficiency Virus

United Kingdom
GeoVax, Inc.
University of Alabama at Birmingham; AIDS Research Consortium of Atlanta; AIDS...

Completed

A Safety and Immunogenicity Study of a Plasmid DNA Prime and MVA Boost Vaccine in HIV-1 Infected Adults on ART

HIV-1 Infection

United States
ST Pharm Co., Ltd.

Recruiting

A Clinical Trial of STP0404 in Treatment-Naïve Adults With HIV-1 Infection

HIV-1-infection

United States
Boehringer Ingelheim

Completed

An Open-label, Non-randomized, Single-arm Study to Investigate the Mechanism(s) by Which Nevirapine Increases Plasma HDL in HIV+ Subjects

HIV Infections | Metabolism, Lipids

Netherlands, United Kingdom
King's College London
Imperial College London; University College, London; Chelsea and Westminster...

Completed

OPEN Study: Pain Management Treatment Needs Interviews

HIV | Peripheral Neuropathy

United Kingdom
Thirty Respiratory Limited

Withdrawn

PREvent Viral Exposure and Transmission Study: a COVID-19 (SARS-CoV-2) PEP Study (PREVENT) (PREVENT)

Respiratory Tract Diseases | COVID-19 Respiratory Infection | Respiratory Viral Infection

United Kingdom

Clinical Trials on Chronic HIV Infections in United Kingdom

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