Clinical Trials on Chronic Kidney Diseases in Czechia

Total 5519 results

University Hospital Hradec Kralove

Unknown

The Aim of This Project is to Verify Whether a Depletion of B Cell Memory Subpopulation ("Marginal-zone-like") CD19 + IgD + CD27 + and CD19 + IgM + CD27 + is a Useful Indicator of Hyposplenism in Patients With Celiac Disease

Celiac Disease

Czechia
St. Anne's University Hospital Brno, Czech Republic
Brno University Hospital; Palacky University

Recruiting

Pre-habilitation in Lung Surgery Candidates

Lung Cancer | Post-Op Complication

Czechia
Inotec AMD Limited

Withdrawn

Pilot Study Comparing NatroxTM Topical Oxygen Therapy to A Placebo in the Management of Non-Healing Leg Ulcers

Skin Ulcer Venous Stasis Chronic | Mixed Arteriovenous Leg Ulcer

Czechia
AbbVie (prior sponsor, Abbott)
Massachusetts General Hospital

Completed

The PRIMO Study: Paricalcitol Capsules Benefits Renal Failure Induced Cardiac Morbidity in Subjects With Chronic Kidney Disease Stage 3/4 (PRIMO)

Chronic Kidney Disease | Left Ventricular Hypertrophy

United States, Australia, Czech Republic, Germany, Italy, Poland, Puerto Rico, Romania, Russian Federation, Spain, Taiwan, United Kingdom
Lexicon Pharmaceuticals
Sanofi

Terminated

Effect of Sotagliflozin on Cardiovascular and Renal Events in Participants With Type 2 Diabetes and Moderate Renal Impairment Who Are at Cardiovascular Risk (SCORED)

Heart Failure | Chronic Kidney Diseases | Type 2 Diabetes Mellitus

Estonia, Belgium, Sweden, Italy, China, United States, Canada, Bulgaria, Chile, Denmark, Hungary, Latvia, Mexico, Russian Federation, Serbia, Spain, Portugal, Romania, Turkey, Poland, Lithuania, Argentina, Australia, Brazil, Czechia, France, Georg... and more
Astellas Pharma Europe B.V.
FibroGen

Completed

Roxadustat in the Treatment of Anemia in End Stage Renal Disease (ESRD) Patients on Stable Dialysis (Pyrenees)

Anemia | End Stage Renal Disease (ESRD)

Bulgaria, Croatia, Czechia, Germany, Hungary, Poland, Russian Federation, Serbia, Spain, United Kingdom, Belgium, France, Georgia, Italy, Portugal, Romania, Slovakia
GlaxoSmithKline

Completed

Anemia Studies in Chronic Kidney Disease: Erythropoiesis Via a Novel Prolyl Hydroxylase Inhibitor Daprodustat-Non-Dialysis (ASCEND-ND)

Anaemia

United States, Australia, Korea, Republic of, Spain, Taiwan, Bulgaria, Canada, Italy, Russian Federation, Ukraine, Argentina, Belgium, France, Philippines, South Africa, Thailand, Israel, Sweden, Singapore, Czechia, Hong Kong, Net... and more
University Hospital Ostrava

Recruiting

Individualized Diagnosis and Treatment of Extraesophageal Reflux in Patients With Chronic Cough

Asthma | Allergy | Laryngopharyngeal Reflux | Chronic Cough | Extraesophageal Reflux

Czechia
European Society for Blood and Marrow Transplantation
Novartis

Completed

Non Interventional Study on Iron Toxicity After First Allo-transplant in MDS/CMML

MDS | CMML

Germany, Belgium, Czechia
Military University Hospital, Prague
Masaryk University

Unknown

Comparison of the Effectiveness of Bowel Preparations Before Colonoscopy

Colorectal Neoplasms

Czechia
Abbott

Completed

Evaluation of the Effectiveness of Paricalcitol Versus Cinacalcet With Low-Dose Vitamin D (IMPACT SHPT)

Hemodialysis | Chronic Kidney Disease | Secondary Hyperparathyroidism

United States, Czech Republic, Denmark, Germany, Greece, Italy, Netherlands, Portugal, Russian Federation, Spain, Sweden, United Kingdom
Amgen

Completed

Efficacy and Safety of Etelcalcetide (AMG 416) in the Treatment of Secondary Hyperparathyroidism (SHPT) in Patients With Chronic Kidney Disease (CKD) on Hemodialysis

Hyperparathyroidism, Secondary

United States, Belgium, Canada, France, Australia, Israel, Czechia, Hungary, Netherlands, Spain, Poland, Russian Federation, Italy, Sweden, Germany
Amgen

Completed

Efficacy and Safety of Etelcalcetide (AMG 416) in the Treatment of Secondary Hyperparathyroidism (SHPT) in Patients With Chronic Kidney Disease on Hemodialysis

Hyperparathyroidism, Secondary

United States, Belgium, Italy, United Kingdom, Canada, Germany, Spain, Austria, Czechia, Hungary, France, Israel, Poland, Australia, Russian Federation
University Hospital Ostrava

Recruiting

The Effect of Chronic Pain and Its Treatment on Quality of Life and Physical Activity

Chronic Pain

Czechia
Amgen

Completed

Extension Study of Etelcalcetide for Treatment of Secondary Hyperparathyroidism in Patients With Chronic Kidney Disease on Hemodialysis

Hyperparathyroidism, Secondary

United States, Belgium, Italy, Switzerland, Canada, Turkey, Spain, Australia, Austria, Israel, Czechia, Hungary, Poland, France, Russian Federation, Germany, Denmark, Greece, Latvia, Lithuania, Netherlands, New Zealand, Portugal, Sweden
Allecra

Completed

Pharmacokinetics of Cefepime and AAI101 in Subjects With Renal Insufficiency and Healthy Subjects

PK in Patients With Various Degrees of Renal Impairment

Czechia, Hungary
Amgen

Completed

Head-to-Head Study of Etelcalcetide (AMG 416) and Cinacalcet

Chronic Kidney Disease | Secondary Hyperparathyroidism

United States, Italy, Belgium, Denmark, Switzerland, Canada, Turkey, Spain, Austria, Germany, Hungary, Greece, France, Poland, Russian Federation, Czechia, Latvia, Lithuania, New Zealand, Portugal, Sweden, Estonia
Institute for Clinical and Experimental Medicine
Czech Academy of Sciences

Recruiting

Gluten-free Diet in PSC and IBD

Biliary Tract Diseases | Ulcerative Colitis | Primary Sclerosing Cholangitis | Intestinal Disease | Biliary Disease Tract

Czechia
Bayer

Completed

Factor XI LICA to Reduce Events Such as Heart Attack and Stroke in Patients Whose Kidneys Are no Longer Able to Work as They Should and Require Treatment to Filter Wastes From the Blood: Focus is on the Safety of BAY2976217 and the Way the Body Absorbs, Distributes and Removes the Study Drug (RE-THINc ESRD)

End Stage Renal Disease Requiring Hemodialysis

Belgium, United States, Latvia, Taiwan, Germany, Japan, Spain, Canada, Bulgaria, Greece, Ukraine, Czechia, Hungary, Korea, Republic of, Russian Federation
University Hospital Ostrava
University Hospital Hradec Kralove

Completed

Balloon Eustachian Tuboplasty in Treatment of Chronic Eustachian Tube Dysfunction

Chronic Eustachian Tube Dysfunction | Chronic Recurrent Otitis Media | Effusion After Tympanostomy

Czechia
University Hospital Ostrava
České Budějovice Hospital

Recruiting

Emergent Microsurgical Intervention in Acute Stroke Patients After Mechanical Thrombectomy Failure Trial (EMIAS)

Acute Stroke | Surgical Procedure

Czechia
Amgen

Completed

Extension Study of Etelcalcetide in the Treatment of Secondary Hyperparathyroidism (SHPT) in Patients With Chronic Kidney Disease (CKD) on Hemodialysis

Hyperparathyroidism, Secondary

United States, Belgium, Italy, United Kingdom, Canada, Germany, Spain, Australia, Austria, Israel, Czechia, Hungary, Netherlands, Poland, France, Russian Federation, Sweden
Zuzana Zbožínková, M.Sc.

Unknown

Czech Multicentre Research Database of Chronic Obstructive Pulmonary Disease (COPD)

Chronic Obstructive Airway Disease

Czechia
AGC Biologics S.p.A.
Horizon 2020 - European Commission

Terminated

Study of CAR T-cell Therapy in Acute Myeloid Leukemia and Multiple Myeloma

Acute Myeloid Leukemia | Multiple Myeloma

Italy, Czechia
Bayer

Completed

An add-on Study to the FIGARO-DKD Study Called FIGARO-BM to Learn About the Link Between Biomarkers (Substances in the Blood Used as Indicators of Biological Processes, Disease Processes or Responses to Medication) and Finerenone in FIGARO-DKD Participants (FIGARO-BM)

Type 2 Diabetes Mellitus | Chronic Kidney Disease

Spain, Belgium, United States, Russian Federation, Hong Kong, Singapore, Taiwan, Korea, Republic of, Canada, Austria, Italy, Japan, Denmark, Australia, Bulgaria, Czechia, Finland, Israel, Netherlands, Sweden, Portugal
The Institute of Molecular and Translational Medicine...
Brno University Hospital; Tomas Bata Hospital, Czech Republic

Completed

Effects of Different Types of Perioperative Analgesia on Minimal Residual Disease Development After Colon Cancer Surgery

Colon Cancer | Minimal Residual Disease

Czechia
Institute for Clinical and Experimental Medicine
Brno University Hospital; Tomas Bata Hospital, Czech Republic; Masaryk Hospital... and other collaborators

Completed

Colorectal Cancer: Screening vs. Non-Screening (CRC)

Colorectal Cancer | Screening

Czechia
SciPharm SàRL

Completed

Efficacy and Tolerability of Subcutaneously Administered Treprostinil Sodium in Patients With Severe (Non-operable) Chronic Thromboembolic Pulmonary Hypertension (CTREPH) (CTREPH)

Non-operable Chronic Thromboembolic Pulmonary Hypertension

Austria, Poland, Czechia, Germany
Astellas Pharma Europe Ltd.

Completed

A Study to Compare How the Body Absorbs and Processes Two Different Formulations of the Anti-rejection Medication Tacrolimus (Advagraf® or Prograf®) in Children Receiving an Organ Transplant, and How Safe and Effective They Are Over a Longer Period of Time

Liver Transplantation | Kidney Transplantation | Heart Transplantation

Czechia, France, Italy, Poland, United Kingdom
Sandoz

Terminated

Randomized, Controlled, Double-blind Multicenter Safety Study to Evaluate the Safety and Immunogenicity of Subcutaneous EPO HEXAL vs. ERYPO® in the Treatment of Anemia Associated With Chronic Renal Insufficiency in Predialysis Patients

Anemia | Chronic Renal Insufficiency

Austria, Slovakia, Russian Federation, Romania, Poland, Czechia, France, Germany, India, Bulgaria
Andreas L. Serra

Unknown

The Eurocyst Initiative: Building a Network of ADPKD Reference Centers Across Europe

Autosomal Dominant Polycystic Kidney Disease

France, Switzerland, Germany, Netherlands, Belgium, Czech Republic, Italy, Spain, Turkey, United Kingdom
Bayer

Completed

Efficacy and Safety of Finerenone in Subjects With Type 2 Diabetes Mellitus and Diabetic Kidney Disease (FIDELIO-DKD)

Chronic Kidney Disease

Belgium, Finland, France, China, Hong Kong, Switzerland, United States, Turkey, Greece, New Zealand, Poland, South Africa, Spain, Korea, Republic of, Portugal, Taiwan, Japan, Russian Federation, Singapore, Australia, Netherlands, ... and more
Charles University, Czech Republic
Ministry of Health, Czech Republic

Unknown

Metabolic Aspects of Citrate Anticoagulation in Renal Replacement Therapy (Citrate)

Critical Illness | Acute Renal Failure

Czech Republic
Institute for Clinical and Experimental Medicine

Unknown

The Role of Insulin Resistance in Patients With Heart Failure and Type 2 Diabetes (CARMET2)

Insulin Resistance | Chronic Heart Failure

Czechia
Bristol-Myers Squibb

Completed

A Study to Assess the Safety of Experimental Medication BMS986165 in Participants With Normal Kidney Function and Participants With Mild to End-Stage Kidney Disease.

Renal Impairment | Healthy Volunteer

United States, Czechia, Hungary, Poland
Novo Nordisk A/S

Completed

Pharmacokinetics, Safety and Tolerability of Oral Semaglutide in Subjects With Various Degrees of Impaired Renal Function

Healthy | Diabetes Mellitus, Type 2 | Diabetes

Hungary, Czechia
Pavol Jozef Safarik University
Europainclinics z.ú.

Unknown

Chronic Low Back Pain - Epiduroscopy Treatment

Chronic Low Back Pain

Slovakia, Czechia
Bayer

Completed

Phase IIb Safety and Efficacy Study of Different Oral Doses of BAY94-8862 in Subjects With Worsening Chronic Heart Failure and Left Ventricular Systolic Dysfunction and Either Type 2 Diabetes Mellitus With or Without Chronic Kidney Disease or Chronic Kidney Disease Alone (ARTS-HF)

Heart Failure

France, Taiwan, United States, Turkey, Spain, Greece, Portugal, Germany, Canada, Austria, Czechia, Denmark, Israel, Korea, Republic of, Poland, South Africa, Sweden, Bulgaria, Italy, Finland, Hungary, Lithuania, Netherlands, Australia, ...
The Institute of Molecular and Translational Medicine...

Completed

Clinical Significance of Detecting CEA and CK20 mRNA-positive Cells in Colorectal Cancer Patients

Colorectal Cancer | Circulating Tumor Cell

Czechia
Novartis Pharmaceuticals

Active, not recruiting

DFF332 as a Single Agent and in Combination With Everolimus & Immuno-Oncology Agents in Advanced/Relapsed Renal Cancer & Other Malignancies

Carcinoma, Renal Cell

Spain, Singapore, Czechia, Italy, Japan, France, United States
Ionis Pharmaceuticals, Inc.

Terminated

A Study to Assess the Safety, Tolerability, and Efficacy of ION-827359 in Participants With Mild to Moderate Chronic Obstructive Pulmonary Disease (COPD) With Chronic Bronchitis (CB)

Chronic Obstructive Pulmonary Disease | Chronic Bronchitis

Germany, Czechia, Hungary, United Kingdom
Value Outcomes Ltd.
AstraZeneca

Completed

Characteristics of Type 2- High Inflammatory Endotype of Asthma Using New Biomarkers From Peripheral Blood and Exhaled Air and Its Effect on the Outcome of Therapy

Asthma, Bronchial | Bronchial Asthma | Asthma Chronic | Asthma; Eosinophilic

Czechia
Boehringer Ingelheim

Completed

OTIVACTO Regional Center Vienna (RCV) Non-Interventional Study (NIS)

Pulmonary Disease, Chronic Obstructive

Austria, Czechia, Hungary, Israel, Romania, Russian Federation, Slovakia, Slovenia, Switzerland
University Hospital Ostrava

Completed

Nutritional Support in Patients Undergoing Surgical Treatment of Colorectal Cancer (NISS)

Colorectal Cancer

Czechia
Amgen

Completed

Bone Biopsy Study For Dialysis Patients With Secondary Hyperparathyroidism of End Stage Renal Disease (BONAFIDE)

Secondary Hyperparathyroidism

United States, Italy, Belgium, Switzerland, Hungary, Spain, Turkey, Poland, Portugal, United Kingdom, Czech Republic, Macedonia, The Former Yugoslav Republic of
Novartis

Completed

Effect of Severe Renal Impairment on Pharmacokinetics and Metabolism of a Single Administration of Licarbazepine

Healthy

Czech Republic
Astellas Pharma Inc

Completed

Renal Impairment Study With ASP1941

Type 2 Diabetes Mellitus

Hungary, Poland, Czechia, Slovakia
University of Jena

Recruiting

European CML Blast Crisis Register (BlastCrisis)

Chronic Myeloid Leukemia in Myeloid Blast Crisis

Germany, Czechia, Russian Federation, Ukraine
Theraclion

Recruiting

Extracorporeal Flow Abolition in Relation With Primary Insufficiency of Great Saphenous Veins (GSV) Using High Intensity Focused Ultrasound (HIFU) Generated by Sonovein: A Multi Center Prospective Pivotal Study (VEINRESET)

Chronic Venous Insufficiency

United States, Czechia, Austria
Biocon Biologics Inc.
MEDA Pharma GmbH & Co. KG; Mylan Inc.; IQVIA Pvt. Ltd

Completed

Hulio Interchangeability to Humira®, Comparing Pharmacokinetics, Efficacy, Safety and Immunogenicity

Moderate Chronic Plaque Psoriasis | Severe Chronic Plaque Psoriasis

Bulgaria, Czechia, Estonia, Poland

Clinical Trials on Chronic Kidney Diseases in Czechia

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