Clinical Trials on Chronic Liver Disease in United Kingdom

Total 147110 results

University College London Hospitals
Medical Research Council

Unknown

Predictive Utility of DASIMAR as a Prognostic Biomarker in Acute-on-chronic Liver Failure (ACLF) (DASIMAR)

Liver Cirrhosis

United Kingdom
University Hospital, Basel, Switzerland
Swiss National Science Foundation

Recruiting

MERTK Signalling in Monocytes/Macrophages in Patients With Liver Disease

Liver Failure | Acute-On-Chronic Liver Failure | Liver Disease | Cirrhosis of the Liver

Switzerland, United Kingdom
Nottingham University Hospitals NHS Trust

Active, not recruiting

REpurposing SirolimUS in Compensated Advanced Chronic Liver Disease. The RESUS Proof of Concept Study (RESUS)

Advanced Chronic Liver Disease

United Kingdom
King's College Hospital NHS Trust
Samsung Medison

Recruiting

Effectiveness of Ultrasound in Liver Stiffness and Fat Quantification

Hepatitis | Liver Fat | NAFLD | Fibrosis, Liver | Liver Disease Chronic | Liver Steatoses | NASH With Fibrosis

United Kingdom
University of Nottingham
Mediplus Ltd UK; Enteric healthcare technology Co-operative

Completed

Evaluation of 'Melody' Paracentesis Device for Ascites Therapy (EMPATHY)

Ascites Hepatic | Cirrhosis and Chronic Liver Disease

United Kingdom
St George's, University of London
King's College Hospital NHS Trust

Recruiting

S100A8/A9 and Innate Immunity in Liver Disease

Infections | Cirrhosis, Liver | Ascites Hepatic | Immune Suppression | Liver Failure, Acute on Chronic

United Kingdom
King's College London
Pfizer

Unknown

An Observational Cohort Study Evaluating Fatty Liver Disease and Liver Fibrosis in Moderate to Severe Psoriasis (CORE)

Fatty Liver | Non-alcoholic Fatty Liver Disease | Liver Fibrosis | Psoriasis Chronic

United Kingdom
Yaqrit Ltd
University College, London; European Foundation for Chronic Liver Failure; Fakkel...

Completed

Safety and Performance Trial of DIALIVE Liver Dialysis Device in Acute On Chronic Liver Failure Patients (DIALIVE _ACLF)

Acute on Chronic Liver Failure

France, Austria, Spain, United Kingdom, Romania, Belgium, Denmark, Germany
Grifols Therapeutics LLC
Instituto Grifols, S.A.

Recruiting

Short-term Survival of Subjects With Acute-on-chronic Liver Failure After Plasma Exchange With Human Serum Albumin 5% (APACHE)

Acute-On-Chronic Liver Failure

United States, United Kingdom, Spain, Germany, Italy, Belgium, France, Austria, Denmark, Portugal
University of Leeds
National Cancer Institute (NCI); Massachusetts General Hospital; Massachusetts... and other collaborators

Recruiting

Prebiotic Effect of Eicosapentaenoic Acid Treatment for Colorectal Cancer Liver Metastases

Colon Cancer Liver Metastasis

United Kingdom
King's College London

Unknown

Methotrexate Polyglutamates as a Marker of Clinical Response and Toxicity in the Treatment of Psoriasis (MTXPG)

Injury of Liver | Psoriasis Chronic

United Kingdom
GlaxoSmithKline

Recruiting

Study of GSK3965193 in Healthy Participants and Participants Living With Chronic Hepatitis B Infection

Hepatitis B

United Kingdom
AstraZeneca
Quotient Sciences

Completed

A Randomised, Open-Label Study to Evaluate the Relative and Absolute Bioavailability of Cotadutide in Healthy Subjects

Chronic Kidney Disease | Type 2 Diabetes Mellitus (T2DM) | Non-alcoholic Steatohepatitis

United Kingdom
Nottingham University Hospitals NHS Trust

Completed

Metformin Therapy in HCV Infection

Chronic Hepatitis C Infection

United Kingdom
University College, London
Schering-Plough

Completed

The Role of Dendritic Cells in Hepatitis C Infection

Chronic Hepatitis C Infection

United Kingdom
Jonel Trebicka

Completed

Predicting Acute-on-Chronic Liver Failure in Cirrhosis (PREDICT) Study (PREDICT)

Liver Cirrhosis With Acute Decompensation

Spain, Germany, Denmark, Austria, Belgium, United Kingdom, Netherlands, Switzerland, Hungary, Italy, France, Portugal, Slovakia, Turkey
Aligos Therapeutics

Terminated

A Study of ALG-020572 Drug to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics After Single Doses in Healthy Volunteers and Multiple Doses in CHB Subjects

Chronic Hepatitis B

United Kingdom, New Zealand
Guy's and St Thomas' NHS Foundation Trust
King's College London

Completed

Safety and Efficacy Study of Regulatory T Cell Therapy in Liver Transplant Patients (ThRIL)

End-stage Liver Disease

United Kingdom
NHS Grampian
University of Aberdeen

Suspended

FCI Effectiveness in NAFLD Stratification (FIELDS)

Non-Alcoholic Fatty Liver Disease

United Kingdom
NHS Tayside

Completed

Evaluation of Multiple HCV Diagnosis Pathways for Efficacy, Cost Effectiveness and Cure in NHS Tayside

Hepatitis C, Chronic

United Kingdom
University College, London
Central and North West London NHS Foundation Trust

Unknown

Sysmex-XN 20 Analyser to Assess Lymphocyte Subsets and Other Haematological Parameters in Chronic/Acute Viral Infections (SASA)

Chronic Hepatitis C | Diagnostic | Chronic HIV Infection | Chronic Viral Hepatitis B

United Kingdom
University of Nottingham

Completed

The Effect of n-3 Polyunsaturated Fatty Acid Supplements in Patients With Non-alcoholic Fatty Liver Disease

Non-alcoholic Fatty Liver Disease

United Kingdom
University of Oxford

Completed

SGLT2 Inhibitors and Metformin on Metabolism and Non-Alcoholic SteatoHepatitis (SMASH)

Non-alcoholic Fatty Liver Disease

United Kingdom
Imperial College London

Completed

A Phase I/II Safety and Tolerability Dose Escalation Study of Autologous Stem Cells to Patients With Liver Insufficiency

Liver Disease

United Kingdom
University of Oxford

Recruiting

Defining Circadian Metabolism in Non-alcoholic Fatty Liver Disease (DECIMAL)

NAFLD

United Kingdom
Imperial College London

Enrolling by invitation

Smart Watch Insights for Prevention of Exacerbations and Enhance Rehabilitation - Movement Study (SWIPER-MOVES)

Cardiovascular Diseases | Diabetes | Respiratory Disease | Non-Alcoholic Fatty Liver Disease

United Kingdom
Guy's and St Thomas' NHS Foundation Trust
King's College London; Medical Research Council; Guts UK

Recruiting

Impact of Cold Exposure on Metabolic Regulation in Children With Non Alcoholic Fatty Liver Disease (NAFLD) (ICE BAT)

Non-Alcoholic Fatty Liver Disease

United Kingdom
University Hospital Southampton NHS Foundation...
National Institute for Health Research, United Kingdom

Completed

Investigation of Synbiotic Treatment in NAFLD (INSYTE)

Non-Alcoholic Fatty Liver Disease

United Kingdom
University of Edinburgh
NHS Lothian

Completed

The Effect Of Omega-3 Fatty Acids on Non-alcoholic Fatty Liver Disease

Non Alcoholic Fatty Liver Disease

United Kingdom
Bruce A. Griffin
Imperial College London; University of Cambridge

Completed

How Does Dietary Carbohydrate Influence the Formation of an Atherogenic Lipoprotein Phenotype (ALP)? (CHOT)

Non-alcoholic Fatty Liver Disease (NAFLD)

United Kingdom
Imperial College London
King's College London

Completed

Impact of FMT on the Phenome in Patients With NAFLD and Fibrosis

Non-Alcoholic Fatty Liver Disease | Fecal Microbiota Transplantation

United Kingdom
University of Bath
Abertay University

Completed

The Effect of HIT in Patients With Non-alcoholic Fatty Liver Disease/Steatohepatitis

Non-alcoholic Fatty Liver Disease | Non-alcoholic Steatohepatitis

United Kingdom
University of Edinburgh
University of Amsterdam; University of Strathclyde

Completed

Breath Analysis Using an Electronic Nose in Non Alcoholic Fatty Liver Disease (BEN)

Non-alcoholic Fatty Liver Disease

United Kingdom
Imperial College London

Completed

Macrophage-mediated Inflammation in White Adipose Tissue and Non-alcoholic Fatty Liver Disease.

Non-Alcoholic Fatty Liver Disease

United Kingdom
King's College Hospital NHS Trust
Merck Sharp & Dohme LLC; Hepatitis C Trust

Terminated

ATTIC - Access To Treat in the Community (ATTIC)

Hepatitis C, Chronic

United Kingdom
Glasgow Royal Infirmary
Glasgow Caledonian University

Unknown

Re-engaging Patients With Hepatitis C Into Care

Hepatitis C, Chronic

United Kingdom
Javelin Pharmaceuticals

Completed

Open-Label, Single-Dose Study to Evaluate the Safety and PK of DIC075V in Subjects With Renal Insufficiency and Hepatic Impairment Compared to Healthy Subjects and Evaluate the Safety and Pharmacokinetics of HPβCD When Administered in DIC075V Compared to Sporanox® in Healthy Subjects

Hepatic Insufficiency | Healthy | Renal Insufficiency, Chronic

United States, United Kingdom
University of Birmingham
National Institute for Health Research, United Kingdom

Unknown

Evaluation of the Mechanisms of Sarcopenia in Chronic Inflammatory Disease: Protocol for a Prospective Cohort Study

Rheumatoid Arthritis | Inflammatory Bowel Diseases | Chronic Liver Disease

United Kingdom
Arrow Therapeutics
DDS, Dundee; David Mutimer, Birmingham; Ed Gane, ACS New Zealand

Terminated

A Study of the PK, Safety and Antiviral Activity of A-831 in HCV Carriers (CP104)

Chronic Hepatitis C

New Zealand, United Kingdom
European Foundation for Study of Chronic Liver...

Recruiting

Liver Transplantation in Patients With CirrHosis and Severe Acute-on-Chronic Liver Failure: iNdications and outComEs (CHANCE)

Liver Diseases | Liver Cirrhosis | Acute-On-Chronic Liver Failure | Liver Transplant; Complications

Spain, United States, Germany, Belgium, United Kingdom, Japan, Mexico, Taiwan, Korea, Republic of, Canada, France, Australia, Italy, Argentina, Austria, Brazil, Colombia, Czechia, Hong Kong, India, Netherlands, New Zealand, Poland, Po... and more
Imperial College London
National Health Service, United Kingdom

Terminated

Rifaximin in Fatty Liver Disease (RiFL)

NAFLD | Nonalcoholic Fatty Liver Disease | Nonalcoholic Steatohepatitis

United Kingdom
Nottingham University Hospitals NHS Trust

Recruiting

Prospective Single Centre Observational Study to Compare the Diagnostic Yield of Different Modalities of Liver Biopsy

Liver Diseases | Liver Fibrosis

United Kingdom
University College London Hospitals

Completed

Analysis of the Duration of Combination Therapy That is Necessary for HCV Genotype 1 Eradication

Chronic Hepatitis C, HCV Genotype 1

United Kingdom
University of Oxford

Recruiting

MRI and Stable Isotope Tracer Studies for Detecting the Progression of Non-Alcoholic Steatohepatitis (NASH) (MRI-Detect)

Non-Alcoholic Fatty Liver Disease

United Kingdom
University Hospital Southampton NHS Foundation...
National Institute for Health Research, United Kingdom

Completed

Treatment of Non Alcoholic Fatty Liver Disease With n-3 Fatty Acids (WELCOME)

Non-Alcoholic Fatty Liver Disease

United Kingdom
King's College Hospital NHS Trust

Active, not recruiting

Contingency Management to Incentivise Treatment Adherence in Alcohol-related Liver Disease

Alcohol-related Liver Disease

United Kingdom
Queen Mary University of London
King's College Hospital NHS Trust; Barts & The London NHS Trust; Homerton University...

Recruiting

Investigating Pathological Mechanisms in Non-alcoholic Fatty Liver Disease

Non-Alcoholic Fatty Liver Disease

United Kingdom
Novo Nordisk A/S

Recruiting

A First Human Dose Study Investigating Safety and Concentration of Study Medicine in the Blood Following Once Daily Oral Dosing of NNC0560-0004 in Healthy Adults.

Healthy Volunteers - Liver Diseases

United Kingdom
University of Edinburgh

Unknown

Thermal Imaging in Liver Disease.

Liver Diseases

United Kingdom
University of Leicester
University Hospitals, Leicester

Recruiting

Tissue Models for Liver Disease (TIMOLD)

Liver Diseases

United Kingdom

Clinical Trials on Chronic Liver Disease in United Kingdom

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