Clinical Trials on Chronic Lung Disease in South Africa

Total 18839 results

University of Witwatersrand, South Africa

Terminated

Safety And Efficacy Of Topical Platelet Rich Plasma And Thrombin Coagulum

Stasis Ulcer

South Africa
Wits Health Consortium (Pty) Ltd
Discovery Vitality

Active, not recruiting

The Vitality Mammography Messaging Study (VMS)

Breast Cancer Female

South Africa
University of Witwatersrand, South Africa
National Institute of Mental Health (NIMH); University of North Carolina, Chapel...

Recruiting

Addressing Intimate Partner Violence, Mental Health, and HIV in Antenatal Care

Depression | Adherence, Medication | Partner Abuse

South Africa
University of Witwatersrand, South Africa

Completed

Exercise for Low Back Pain in Children (LBP)

Low Back Pain

South Africa
hearX Group
University of Pretoria

Completed

Clinical Validation of the Lexie Lumen Hearing Aid

Hearing Loss

South Africa
Duke University
National Institute of Mental Health (NIMH); University of Cape Town

Completed

Improving the Health of South African Women With Traumatic Stress in HIV Care (ImpACT)

HIV | Trauma Exposure

South Africa
DMG Dental Material Gesellschaft mbH
Dental Wellness Trust (DWT); University of Western Cape (UWC)

Completed

Fluoride Varnish Community Trial

Dental Caries | Oral Disease | Costs

South Africa
AstraZeneca
Quintiles, Inc.

Completed

Adherence Study in COPD Patients

Chronic Obstructive Pulmonary Disease (COPD

United States
University of Witwatersrand, South Africa
GlaxoSmithKline; University of Oxford; Medical Research Council, South Africa; University...

Completed

Determinants of Type 2 Diabetes Risk in Middle-aged Black South African Men and Women

Diabetes Mellitus, Type 2 | Insulin Resistance | Menopause | Hiv

South Africa
hearX Group

Completed

Comparing Self-Fitting Strategies in the Lexie Powered by Bose Hearing Aids

Hearing Loss

South Africa
University of Johannesburg
Medical Research Council, South Africa

Enrolling by invitation

Evaluation of the Impact of a Personal and Domestic Hygiene Intervention on Lead Exposure in a Community Close to a Mine Dump

Lead Poisoning | Lead Poison Children

South Africa
Swiss Federal Institute of Technology
University of Stellenbosch

Recruiting

Potential of Prebiotic Galacto-oligosaccharides in Improving Efficacy and Safety of Oral Iron Supplementation in HIV-infected Children

HIV | Iron Deficiency

South Africa
Wits Health Consortium (Pty) Ltd
London School of Hygiene and Tropical Medicine; King's College London; Karolinska... and other collaborators

Completed

The CHAPS Trial: Combined HIV Adolescent PrEP and Prevention (CHAPS)

HIV/AIDS

South Africa
UMC Utrecht
ZonMw: The Netherlands Organisation for Health Research and Development; Wits... and other collaborators

Completed

The Intensified Treatment Monitoring Strategy to Prevent Accumulation of Drug Resistance (ITREMA) Trial (ITREMA)

HIV/AIDS

South Africa
Duke University
The Emmes Company, LLC

Recruiting

Pharmacokinetics of Antiretroviral Drugs in Lactating Women and Breastmilk Fed Infants Under 6 Months of Age in Botswana (BMS02)

HIV Infections | Lactating Women on Select DOI | Breastmilk Fed Infants of Mothers on Select DOI

South Africa
University of Johannesburg

Completed

The Effect of Individualised Homoeopathic Treatment of Autism Spectrum Disorder in Children

Autism Spectrum Disorder

South Africa
Johns Hopkins University
National Cancer Institute (NCI); New York University; Colorado State University; Perinatal HIV Research Unit of the University of the Witswatersrand

Recruiting

Evaluating Smoking Cessation Interventions for PWH in South Africa (Tlogela)

Smoking Cessation | HIV | Comorbidities and Coexisting Conditions

South Africa
Professor Francois Venter

Completed

DORA: A Doravirine-based First-line Antiretroviral Therapy for Women of Reproductive Potential Living With HIV (DORA)

HIV-1-infection

South Africa
Boston University
Bill and Melinda Gates Foundation; University of Witwatersrand, South Africa

Completed

Revised Simplified Algorithm for Treatment Eligibility for HIV (SLATEII) (SLATEII)

HIV/AIDS | Antiretroviral Therapy

South Africa
Boston University
National Institute of Allergy and Infectious Diseases (NIAID); University of...

Completed

Rapid Initiation of Antiretroviral Therapy to Promote Early HIV/AIDS Treatment in South Africa (RapIT Study) (RapIT)

HIV

South Africa
Istituto Superiore di Sanità

Recruiting

Extended Follow-Up of the ISS T-003 Trial Volunteers (ISS T-003 EF-UP2020) (T003EFUP2020)

HIV Infections

South Africa
Johns Hopkins University
University of Cape Town

Terminated

Helping HIV Infected Patients in South Africa Adhere to Drug Regimens

HIV Infections

South Africa
University of California, Los Angeles
Gilead Sciences; University of Cape Town; Desmond Tutu HIV Foundation

Completed

PK of TAF and TDF for PrEP in Pregnant and Postpartum Women (PrEP-PP PK)

Hiv

South Africa
University of California, Los Angeles
University of Cape Town; Desmond Tutu HIV Foundation

Completed

Evaluation of Pre-exposure Prophylaxis Cascade in Pregnant and Breastfeeding Women in Cape Town (Formative Study) (PrEP-PP)

Hiv

South Africa
Queen Mary University of London
National Institute for Health Research, United Kingdom

Completed

Achieving Control of Asthma in Children In Africa (ACACIA)

Asthma

Ghana, Malawi, Nigeria, South Africa, Uganda, Zimbabwe
National Institute of Allergy and Infectious Diseases...
United States Agency for International Development (USAID)

Completed

Social and Economic Outcomes of HIV/AIDS Care and Treatment in HIV Infected South African Adults

HIV Infections

South Africa
University of Witwatersrand, South Africa

Completed

Validation of Implementation of Cervical Dysplasia Treatment Modalities in HIV-Seropositive Women (VICAR2)

Cervical Intraepithelial Neoplasia

South Africa
Columbia University
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Treatment Options for Protease Inhibitor-exposed Children (NEVEREST-III)

HIV Infections | HIV/AIDS

South Africa
University of Oxford
University of Cape Town

Completed

A Study of MVA85A, in Asymptomatic Volunteers Infected With TB, HIV or Both

HIV Infections | TB

South Africa
NYU Langone Health
JOHN E FOGARTY INTERNATIONAL CENTER FOR ADVANCED STUDY IN THE HEALTH SCIENCES...

Not yet recruiting

E-cigarette Harm Reduction Among PLWHA in South Africa

Tobacco Smoking

South Africa
University of Virginia
University of Venda

Active, not recruiting

Effectiveness of Point-of-use Water Treatment Technologies to Prevent Stunting Among Children in South Africa

Environmental Exposure | Diarrhoea;Infectious;Presumed | Diarrhea, Infantile | Diarrhea Tropical | Enteropathy | Malnutrition, Child

South Africa
University of the Western Cape
Karolinska University Hospital; Karolinska Institutet; Medical Research Council...

Unknown

Strengthening Health Systems for Persons With Traumatic Spinal Cord Injury in South Africa and Sweden

Spinal Cord Injuries

South Africa
Boehringer Ingelheim

Completed

12 Week Comparison of 5 Mcg and 10 Mcg of Tiotropium / Respimat, Placebo and Ipratropium MDI in COPD

Pulmonary Disease, Chronic Obstructive

Germany, Italy, Switzerland, South Africa
World Bank
Department for International Development, United Kingdom; Wits Reproductive... and other collaborators

Completed

Smart Linkage-to-HIV Care Via a Smartphone App (SmartLtC)

HIV Infections | Antiretroviral Therapy | Patient Compliance | Viral Load | Cell Phone

South Africa
University of Cape Town

Unknown

Pregnancy-Related Obesity Prevention Through Education & Communication Technology in AFRICA:The PROTECT-AFRICA STUDY (PROTECT-AFRI)

Obesity

South Africa
GlaxoSmithKline

Completed

Primary and Booster Vaccination Study With a Pneumococcal Vaccine in HIV Infected, HIV Exposed Uninfected and HIV Uninfected Children 6 to 10 Weeks of Age.

Infections, Streptococcal

South Africa
Novartis Pharmaceuticals

Completed

Efficacy and Safety of QMF149 vs. Salmeterol Xinafoate/Fluticasone Propionate in Patients With Chronic Obstructive Pulmonary Disease (COPD)

COPD

Spain, Germany, Belgium, Poland, South Africa, Australia, Greece, Israel, Sweden, Hong Kong, Thailand, Bulgaria, Singapore, Denmark, Finland, Hungary, Romania, Malaysia
University of California, San Francisco
National Institute of Allergy and Infectious Diseases (NIAID); University Hospital... and other collaborators

Not yet recruiting

Pragmatic Use of Next-generation Sequencing for Management of Drug-resistant Tuberculosis (TSELiOT)

Drug-resistant Tuberculosis | Cost-Benefit Analysis | HIV Coinfection

South Africa
Vakzine Projekt Management GmbH
University of Stellenbosch; Children's Infectious Diseases Clinical Research... and other collaborators

Completed

Study to Evaluate Safety and Immunogenicity of VPM1002 in Comparison With BCG in Newborn Infants in South Africa

Tuberculosis

South Africa
Mark Hatherill
Medical Research Council; University of Oxford; Wellcome Trust; Department for... and other collaborators

Completed

Safety and Immunogenicity of MVA85A Prime and Bacille Calmette-Guerin Boost Vaccination (MVA(TB)029)

HIV | Tuberculosis

South Africa
Novartis
Novartis Vaccines

Withdrawn

Antibody Levels Associated With Reduced Risk of Invasive Group B Streptococcus Disease in Infants Aged Less Than 90 Days

Invasive Group B Streptococcus Disease

South Africa
University of Johannesburg

Completed

The Effect of Individualised Homeopathic Treatment on Low Sexual Desire in Perimenopause

Hypoactive Sexual Desire Disorder

South Africa
Professor Francois Venter
Merck Sharp & Dohme LLC; Africa Health Research Institute

Recruiting

A Randomised, Phase 3 Non-inferiority Study of DOR/3TC/TDF Compared to DTG/TAF/FTC in Participants Infected With HIV-1 Starting First-line Antiretroviral Therapy (Opti-DOR)

HIV-1-infection

South Africa
Professor Francois Venter
University of Cape Town

Completed

The Effect of Rifampicin on the Pharmacokinetics of Intracellular Tenofovir-diphosphate and Tenofovir When Coadministered With Tenofovir Alafenamide Fumarate During the Maintenance Phase of Tuberculosis Treatment in TB/HIV-1 Coinfected Participants (EpiTAF)

Tuberculosis | HIV-1-infection

South Africa
University of Witwatersrand, South Africa

Completed

Intrathecal Opioid Study

Post-operative Pain

South Africa
Bill & Melinda Gates Medical Research Institute

Completed

Early Bactericidal Activity of TBA-7371 in Pulmonary Tuberculosis

Pulmonary Tuberculosis

South Africa
Johns Hopkins Bloomberg School of Public Health
Perinatal HIV Research Unit of the University of the Witswatersrand; Setshaba...

Active, not recruiting

Kharituwe TB Contact Tracing Study

Tuberculosis | Hiv

South Africa
AstraZeneca

Completed

Efficacy and Safety of Ciclesonide (CIC) Administered Twice Daily in Pediatric Patients With Asthma.

Asthma

Russian Federation, Hungary, South Africa, Mexico, United States, Poland
Harriet Shezi Children's Clinic

Unknown

Dosing, Safety and Pharmacokinetic Profile of Rifabutin in Children Receiving Concomitant Treatment With Kaletra (RBT)

Children With Confirmed HIV Infection | Receiving ART Regimen Containing 2 NRTIs + LPV/RTV at Standard Dose | Successfully Completed TB Treatment in the Past 2 to 6 Weeks of Enrollment

South Africa
Aeras
Sanofi Pasteur, a Sanofi Company; Statens Serum Institut; HIV Vaccine Trials...

Completed

Safety and Immunogenicity Study of BCG, H4:IC31, and H56:IC31 Revaccination in Healthy Adolescents

Tuberculosis

South Africa

Clinical Trials on Chronic Lung Disease in South Africa

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Kenya

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Rare Diseases

Drug Interventions

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