Clinical Trials on Chronic Obstructive Pulmonary Disease (COPD) in United States

Total 18922 results

AstraZeneca
Parexel

Completed

Efficacy, Pharmacokinetics (PK), Safety and Tolerability Study of Inhaled AZD8871

Chronic Obstructive Pulmonary Disease COPD

Germany, United Kingdom
Chiesi Farmaceutici S.p.A.

Completed

Safety and Efficacy Study of Glyco pMDI After Single and Repeated Administration (GLY2)

Chronic Obstructive Pulmonary Disease (COPD)

United Kingdom
Cardiff University
GlaxoSmithKline; Cardiff Metropolitan University

Completed

Assessment of Risk in Chronic Airways Disease Evaluation (ARCADE)

Chronic Obstructive Pulmonary Disease (COPD)

United Kingdom
University of Michigan
National Heart, Lung, and Blood Institute (NHLBI)

Completed

RETHINC: REdefining THerapy In Early COPD for the Pulmonary Trials Cooperative (RETHINC)

COPD (Chronic Obstructive Pulmonary Disease)

United States
University Hospital Southampton NHS Foundation...
GlaxoSmithKline

Completed

Microbiology & Immunology of the Chronically-inflamed Airway (MICA)

Chronic Obstructive Pulmonary Disease (COPD)

United Kingdom
AstraZeneca
Parexel

Completed

Formoterol Dose Ranging Study (ACHIEVE Duaklir USA Phase IIb)

Chronic Obstructive Pulmonary Disease - COPD

United States
Sunovion

Terminated

A Study of Arformoterol Tartrate Inhalation Solution and Tiotropium Bromide on Re-hospitalization in Chronic Obstructive Pulmonary Disease (COPD) Subjects

Chronic Obstructive Pulmonary Disease (COPD)

United States
StratiHealth

Completed

Use of Respiratory Therapists (RTs) to Improve Outcomes and Quality of Life in Patients With COPD (RTQOL)

Chronic Obstructive Pulmonary Disease (COPD)

United States
Almirall, S.A.
Forest Laboratories

Completed

Preference, Satisfaction and Ease of Use of Genuair® (Pressair™) and Breezhaler® (Neohaler™) Inhalers in Patients With COPD

Chronic Obstructive Pulmonary Disease (COPD)

Germany, Spain, United Kingdom
Sunovion Respiratory Development Inc.

Completed

A Long-Term Safety Trial of Treatment With Nebulized SUN-101 in Patients With COPD (GOLDEN-5)

Chronic Obstructive Pulmonary Disease (COPD)

United States, Czechia, Hungary, Russian Federation
Novartis Pharmaceuticals

Completed

Efficacy and Safety of Indacaterol Plus Tiotropium Versus Tiotropium Alone in Patients With Chronic Obstructive Pulmonary Disease (INTRUST1)

Chronic Obstructive Pulmonary Disease (COPD)

United States, Colombia, Argentina, Germany, Spain, Turkey, Guatemala, Mexico, Australia, Denmark, South Africa, Philippines
Imperial College London

Completed

Effects of Long Term Antibiotic Therapy on Exacerbation Rate in Stable COPD Patients

Chronic Obstructive Pulmonary Disease (COPD)

United Kingdom
Novartis Pharmaceuticals

Completed

A Safety, Tolerability and Efficacy Study With QBW251 in COPD Patients With QBW251

Chronic Obstructive Pulmonary Disease, COPD

Poland, United States
Sheffield Teaching Hospitals NHS Foundation Trust
University of Sheffield; National Institute for Health Research: CLAHRC YH; The... and other collaborators

Completed

Use of the SMART COPD Physical Activity App in Pulmonary Rehabilitation

Chronic Obstructive Pulmonary Disease (COPD)

United Kingdom
Loughborough University

Completed

Sedentary Behaviour, Physical Activity and Cardiometabolic Risk in Chronic Obstructive Pulmonary Disease (SPAaRC)

COPD

United Kingdom
Respivert Ltd

Completed

Safety, Tolerability and Pharmacokinetics (PK) of RV1162 in Healthy Subjects and COPD Patients

Healthy Volunteers | Chronic Obstructive Pulmonary Disease (COPD)

United Kingdom
AstraZeneca

Completed

Evaluate the Effect of Aclidinium Bromide on Long-term Cardiovascular Safety and Exacerbations in Moderate to Very Severe COPD Patients. (ASCENT COPD)

Chronic Obstructive Pulmonary Disease | COPD | Moderate to Very Severe COPD

United States, Canada
Guy's and St Thomas' NHS Foundation Trust
King's College London; University of Nottingham; Imperial College London; University... and other collaborators

Not yet recruiting

Supported Rescue Packs Post-discharge in Chronic Obstructive Pulmonary Disease (RAPID)

COPD | COPD Exacerbation

United Kingdom
AstraZeneca

Completed

Evaluation of an Oxygen Enhanced Magnetic Resonance Imaging Method on Patients With Chronic Obstructive Pulmonary Disease During 8 Weeks Treatment With Either Symbicort Turbuhaler or Oxis Turbuhaler

COPD Method Evaluation | Chronic Obstructive Pulmonary Disease Method Evaluation

United Kingdom, Sweden
Patrick Murphy
Philips Respironics

Completed

Validation of the AVAPS AE Algorithm in Chronic Obstructive Pulmonary Disease (COPD) Patients (AVAPS-AE)

OSA | COPD

United Kingdom
Mayo Clinic
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Home Pulmonary Rehabilitation for COPD

Emphysema | Chronic Obstructive Pulmonary Disease (COPD)

United States
Glenmark Specialty S.A.

Completed

Pharmacodynamic and Pharmacokinetic Dose Ranging Study of Tiotropium Bromide Administered Via Inhalation Solution in Patients With Chronic Obstructive Pulmonary Disease (COPD)

Mild to Moderate Chronic Obstructive Pulmonary Disease (COPD)

United States
Novartis Pharmaceuticals

Completed

Efficacy and Safety of Indacaterol Plus Tiotropium Versus Tiotropium Alone in Patients With Chronic Obstructive Pulmonary Disease (INTRUST2)

Chronic Obstructive Pulmonary Disease (COPD)

United States, Colombia, Spain, Canada, Slovakia, India, Netherlands, Czech Republic, Hungary
University of California, Los Angeles
Dey, L.P.

Withdrawn

Perforomist Versus Foradil Evaluated by Inspiratory Capacity and High Resolution Computed Tomography (HRCT)

Chronic Obstructive Pulmonary Disease | Emphysema | COPD | Chronic Bronchitis

United States
AstraZeneca

Completed

Efficacy and Safety of Aclidinium Bromide 400 µg BID (Twice a Day)Compared to Placebo in Patients With Stable Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD)

Chronic Obstructive Pulmonary Disease (COPD)

Germany, Spain, United Kingdom
AstraZeneca

Completed

A Study to Assess the Bioavailability and to Compare the Pharmacokinetics of AZD7594 Inhaled Via Monodose Inhaler and Multiple-dose Dry Powder Inhalers (DPI) or Pressurized Metered-dose Inhaler (pMDI) in Healthy Male Subjects

Asthma | Chronic Obstructive Pulmonary Disease (COPD)

United States
National Jewish Health
GlaxoSmithKline

Terminated

Evaluating Genes in Sputum to Measure Drug Response in COPD

Emphysema | Chronic Obstructive Pulmonary Disease (COPD) | Chronic Bronchitis

United States
Novartis Pharmaceuticals

Completed

Comparison of Long-term Safety of the Combination Product QVA149A Against Placebo and Standard of Care Treatment in Chronic Obstructive Pulmonary Disease Patients With Moderate to Severe Airflow Limitation

Chronic Obstructive Pulmonary Disease (COPD)

Colombia, India, Korea, Republic of, Poland, Croatia, Estonia, Hungary, United Kingdom, Israel, Latvia, Turkey, Argentina, Panama, Mexico, Russian Federation, Serbia, Slovenia
Sunovion Respiratory Development Inc.

Completed

A Study of the Efficacy and Safety of EP-101 ( (SUN101) in Subjects With Moderate to Severe Chronic Obstructive Pulmonary Disease (GOLDEN-2)

COPD

United States
Asante Health System
Health Resources and Services Administration (HRSA)

Completed

A Trial to Reduce Readmissions Using Motivational Interviewing and Interactive Voice Response

Chronic Obstructive Pulmonary Disease (COPD) | Congestive Heart Failure (CHF)

United States
AstraZeneca

Completed

Effect of Roflumilast on Exacerbation Rate in Patients With Chronic Obstructive Pulmonary Disease (COPD): The HERMES Study (BY217/M2-125)

Chronic Obstructive Pulmonary Disease (COPD)

Germany, Spain, United States, Canada, India, Italy, Poland, South Africa
AstraZeneca

Completed

Effect of Roflumilast on Lung Function in Chronic Obstructive Pulmonary Disease (COPD) Patients Treated With Salmeterol: The EOS Study (BY217/M2-127) (EOS)

Chronic Obstructive Pulmonary Disease (COPD)

Austria, Belgium, Canada, France, Germany, Italy, Netherlands, South Africa, Spain, United Kingdom
Alkermes, Inc.

Completed

ALK27-001: A Study of Trospium Inhalation Powder (TrIP)Administered to Subjects With COPD

Chronic Obstructive Pulmonary Disease (COPD)

United States
University of California, Los Angeles
Sunovion

Unknown

Sunovion Brovana Versus Serevent Inspiratory Capacity High Resolution Computed Tomography

Chronic Obstructive Pulmonary Disease | Emphysema | COPD | Chronic Bronchitis

United States
StratiHealth

Completed

Portable Oxygen Concentrator to Improve Quality of Life in Chronic Obstructive Pulmonary Disease

COPD

United States
Sensorum Health Inc.

Recruiting

Evaluation of Home-based Sensor System to Detect Health Decompensation in Elderly Patients With History of CHF or COPD

Chronic Obstructive Pulmonary Disease | COPD | COPD Exacerbation | Congestive Heart Failure | CHF

United States
Columbia University
National Heart, Lung, and Blood Institute (NHLBI)

Terminated

Imaging of Peri-operative (periOP) Lung Injury

Acute Lung Injury | Chronic Obstructive Pulmonary Disease (COPD)

United States
Sunovion

Completed

A Pivotal Study of the Safety and Effectiveness of Arformoterol in Subjects With Chronic Obstructive Pulmonary Disease (COPD)

COPD

United States
AstraZeneca

Completed

Clinical Trial to Assess Rate of Onset of Bronchodilator Action in Severe Stable Chronic Obstructive Pulmonary Disease (COPD) Patients

Chronic Obstructive Pulmonary Disease (COPD)

United Kingdom
AstraZeneca

Completed

Trial to Assess the Anti-inflammatory Effects of Roflumilast in Chronic Obstructive Pulmonary Disease

Chronic Obstructive Pulmonary Disease | COPD

Poland, United Kingdom, Germany, Sweden, Denmark
Sunovion Respiratory Development Inc.

Completed

Efficacy and Safety Trial of 12 Weeks of Treatment With Nebulized SUN-101 in Patients With COPD (GOLDEN-4) (GOLDEN-4)

Chronic Obstructive Pulmonary Disease | COPD

United States
Pearl Therapeutics, Inc.

Completed

Study to Assess the Safety and Tolerability of PT010, PT009 and PT003 in Subjects With Moderate to Very Severe Chronic Obstructive Pulmonary Disease

COPD

United States
AstraZeneca

Completed

Effect of Roflumilast on Exacerbation Rate in Patients With Chronic Obstructive Pulmonary Disease. Ratio-Study. (BY217/M2-112)

Chronic Obstructive Pulmonary Disease | COPD

Austria, France, Hungary, Italy, Poland, Portugal, Russian Federation, South Africa, Spain, Canada, United Kingdom, Australia, Netherlands, Switzerland
Nuvaira, Inc.

Completed

Targeted Lung Denervation for Patients With Moderate to Severe COPD (AIRFLOW)

Chronic Obstructive Pulmonary Disease (COPD)

France, Belgium, Netherlands, Austria, Germany, United Kingdom
Weill Medical College of Cornell University
National Heart, Lung, and Blood Institute (NHLBI); University of Michigan; Duke... and other collaborators

Completed

The CAPTURE Study: Validating a Unique COPD Case Finding Tool in Primary Care (Aim 1) (CAPTURE)

Chronic Obstructive Pulmonary Disease (COPD)

United States
Mylan Inc.
Theravance Biopharma

Completed

Revefenacin Peak Inspiratory Flow Rate (PIFR) Study in COPD

Chronic Obstructive Pulmonary Disease, COPD | Low Peak Inspiratory Flow Rate (PIFR)

United States
Weill Medical College of Cornell University
National Heart, Lung, and Blood Institute (NHLBI); University of Michigan; Duke... and other collaborators

Completed

The CAPTURE Study: Validating a Unique COPD Case Finding Tool in Primary Care (Aim 3) (CAPTURE)

Chronic Obstructive Pulmonary Disease (COPD)

United States
Sunovion

Completed

Efficacy and Safety of Levalbuterol in Chronic Obstructive Pulmonary Disease (COPD)

Chronic Obstructive Pulmonary Disease (COPD)

United States, Canada
Novartis Pharmaceuticals

Completed

Long Term Safety Study of NVA237 vs QAB149 in COPD Patients

Chronic Obstructive Pulmonary Disease (COPD)

United States
NuvoAir Medical PC

Recruiting

Pragmatic Assessment of the NuvoAir Clinical Service in the Management of Patients With Chronic Obstructive Pulmonary Disease (PROMISE)

COPD | Comorbidities and Coexisting Conditions

United States

Clinical Trials on Chronic Obstructive Pulmonary Disease (COPD) in United States

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