Clinical Trials on Chronic Disabling

Total 32373 results

Universidad de Almeria
Torrecárdenas Hospital; Almería Health District

Completed

Multiple Chronic Diseases: the RITH Trial

Multiple Chronic Diseases

Spain
Gruppo Italiano Malattie EMatologiche dell'Adulto

Completed

Nilotinib and Imatinib Mesylate in Treating Patients With Early Chronic Phase Chronic Myelogenous Leukemia (CML0408)

Leukemia

Italy
Marcus Maurer

Completed

Profiling Urticaria for the Identification of Subtypes (PURIST)

Non-autoreactive Chronic Spontaneous Urticaria | Autoimmune Chronic Spontaneous Urticaria | Autoreactive, Non-autoimmune Chronic Spontaneous Urticaria

Germany
Johnson & Johnson Pharmaceutical Research & Development...
Ortho Biotech Clinical Affairs, L.L.C.

Completed

A Study of the Use of PROCRIT (Epoetin Alfa) for the Treatment of Anemia in People With Chronic Kidney Disease Who Live in Long-term Care Facilities.

Anemia | Renal Failure , Chronic
Ascentage Pharma Group Inc.

Not yet recruiting

A Phase 3 Registrational Study of Olverembatinib (HQP1351) in Patients With CML (POLARIS-2)

Chronic Myeloid Leukemia | CML | CML, Chronic Phase

United States
Siriraj Hospital

Recruiting

The Evaluation and Comparison of BCR-ABL p210 mRNA Transcripts (%IS Unit) Results Between Dr. PCR™ BCR-ABL1 Major IS Detection Kit (Optolane) and QXDx™ BCR-ABL %IS Kit (Bio-Rad) in Chronic Myeloid Leukemia Patients (BCR-ABL1)

Chronic Myelogenous Leukemia

Thailand
Chiesi Farmaceutici S.p.A.

Recruiting

A 52-week, Placebo- and Active- Controlled (Roflumilast, Daliresp® 500µg) Study to Evaluate the Efficacy and Safety of Two Doses of CHF6001 DPI (Tanimilast) as add-on to Maintenance Triple Therapy in Subjects With COPD and Chronic Bronchitis. (PILLAR) (PILLAR)

Chronic Obstructive Pulmonary Disease

Bulgaria, United States, Argentina, Austria, Bosnia and Herzegovina, Chile, Croatia, Czechia, Estonia, Germany, Greece, Hungary, Israel, Latvia, Mexico, Netherlands, New Zealand, North Macedonia, Poland, Romania, Russian Federation and more
Karaganda Medical University

Completed

Association of Cathelicidin and Vitamin D Levels With the Category and Course of COPD (COPD)

Chronic Obstructive Pulmonary Disease | Chronic Obstructive Pulmonary Disease Moderate | Chronic Obstructive Pulmonary Disease Severe

Kazakhstan
Qing XIe

Recruiting

Pegylated Interferon α in Previously Interferon-treated CHB（Leading Study）

Chronic Hepatitis b

China
Terns, Inc.

Not yet recruiting

CARDINAL- A Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Efficacy of TERN-701 in Participants With Chronic Myeloid Leukemia

Chronic Myeloid Leukemia | Chronic Myeloid Leukemia, Chronic Phase

United States
Suzhou Ribo Life Science Co. Ltd.

Recruiting

A Study of RBD1016 in CHB Participants

Chronic Hepatitis b

Sweden
Associazione Italiana Pazienti Leucemia Mieloide...

Not yet recruiting

Cardiovascular Assessment of Ponatinib as Third Line Treatment in Chronic Phase Chronic Myeloid Leukemia (CarPAs)

Chronic Myeloid Leukemia (CML)

Italy
Young-Suk Lim
Samsung Medical Center; Seoul St. Mary's Hospital; China Medical University Hospital and other collaborators

Recruiting

Effectiveness of TAF in Reducing Clinical Events in CHB Patients Beyond Treatment Indications by Current Guidelines (ATTENTION)

Chronic Hepatitis b

Korea, Republic of
University Hospital, Clermont-Ferrand
Centre Leon Berard; Versailles Hospital; University Hospital, Grenoble; Institut... and other collaborators

Recruiting

EPIgenetics and in Vivo Resistance of Chronic Myeloid Leukemia Stem Cells to Tyrosine Kinase Inhibitors (EPIK)

Chronic Myeloid Leukemia (CML) | Chronic Phase

France
Temple University
National Center for Complementary and Integrative Health (NCCIH); Quercegen...

Recruiting

Biological Effects of Quercetin in COPD Phase II (polyphenols)

Chronic Obstructive Pulmonary Disease | Emphysema | Chronic Bronchitis With Airway Obstruction

United States
Ascletis Pharmaceuticals Co., Ltd.
Peking University First Hospital; Beijing Clinical Service Center

Active, not recruiting

A Phase II Study of Subcutaneously Injected PD-L1 Antibody ASC22 in Chronic Hepatitis B Patients

Chronic Hepatitis b

China
Suzhou Ribo Life Science Co. Ltd.

Completed

A Single and Repeated Dose Escalation of RBD1016 in Subjects With Chronic Hepatitis B Virus (HBV) Infection

Chronic Hepatitis b

China
Mayo Clinic
National Cancer Institute (NCI)

Completed

Imprime PGG, Alemtuzumab, and Rituximab in Treating Patients With High Risk Chronic Lymphocytic Leukemia

B-cell Chronic Lymphocytic Leukemia | Refractory Chronic Lymphocytic Leukemia | Stage 0 Chronic Lymphocytic Leukemia | Stage I Chronic Lymphocytic Leukemia | Stage II Chronic Lymphocytic Leukemia

United States
National Cancer Institute (NCI)

Completed

Fludarabine, Rituximab, and Alemtuzumab in Treating Patients With Chronic Lymphocytic Leukemia

B-cell Chronic Lymphocytic Leukemia | Stage I Chronic Lymphocytic Leukemia | Stage II Chronic Lymphocytic Leukemia | Stage III Chronic Lymphocytic Leukemia | Stage IV Chronic Lymphocytic Leukemia

United States
Memorial Sloan Kettering Cancer Center

Active, not recruiting

Study of a Geriatric Assessment to Plan a Treatment Approach for Older People With Various Blood Disorders

Chronic Myelomonocytic Leukemia | Myelodysplastic Syndrome | Myeloproliferative Neoplasms | Atypical Chronic Myeloid Leukemia | Myelodysplastic/Myeloproliferative Overlapping Syndrome

United States
Gilead Sciences

Recruiting

Study of Bulevirtide in Participants Who Have Normal or Impaired Liver Function

Chronic Hepatitis D Infection

United States
Hamad Medical Corporation

Terminated

Dasatinib Versus Nilotinib for Treatment Naïve Chronic Myeloid Leukemia (DANIN)

Chronic Myeloid Leukemia - Chronic Phase

Qatar
Arbeitsgemeinschaft medikamentoese Tumortherapie
AOP Orphan Pharmaceuticals AG

Completed

Addition of P1101 to Imatinib Treatment in Patients With Chronic Phase Chronic Myeloid Leukaemia Not Achieving a Complete Molecular Response

Chronic Phase Chronic Myeloid Leukemia

Austria
University of Michigan Rogel Cancer Center

Terminated

Discontinuation of Imatinib Mesylate in Patients With Chronic-Phase Chronic Myeloid Leukemia Previously Treated With Interferon-Alpha

Chronic Myeloid Leukemia

United States
Memorial Sloan Kettering Cancer Center
National Cancer Institute (NCI)

Completed

Interferon Alfa and Imatinib Mesylate in Treating Patients With Chronic Myelogenous Leukemia

Leukemia

United States
Novartis Pharmaceuticals

Completed

Everolimus and Imatinib Mesylate in Treating Patients With Chronic Phase Chronic Myelogenous Leukemia Who Are Not in Complete Cytogenetic Remission After Previous Imatinib Mesylate

Leukemia

United States
Aveiro University

Active, not recruiting

A Pilot Study of a Neural Mobilization Intervention Applied to Older Adults With Chronic Musculoskeletal Pain

Chronic Pain | Older Adults | Chronic Musculoskeletal Pain | Chronic Musculoskeletal Disease

Portugal
University Hospital, Limoges

Terminated

Pharmacokinetics of an Aminoglycoside in Hemodialysis Patients. (DIAMS)

Renal Failure Chronic Requiring Hemodialysis

France
Fundación Senefro

Unknown

Study to Explore Morbimortality in Patients Dialyzed With the Theranova HDx in Comparison to On-Line-Hemodiafiltration

Chronic Kidney Disease Requiring Chronic Dialysis

Spain
Baxter Healthcare Corporation
University of California, Davis; Vanderbilt University Medical Center; University... and other collaborators

Completed

Study of How the Dose of Dialysis is Affected by Dialysate Flow Rate

Chronic Kidney Disease | Chronic Renal Disease

United States
Hospital Universitario Infanta Leonor

Completed

Cellulose Triacetate Dialyzer in Hemodiafiltration-online

Chronic Kidney Disease Requiring Chronic Dialysis

Spain
National Taiwan University Hospital
Mackay Memorial Hospital; Shin Kong Wu Ho-Su Memorial Hospital; Taipei Medical... and other collaborators

Unknown

Renoprotection by Pentoxifylline and Angiotensin Receptor Blocker in Chronic Kidney Disease (CKD) (CKD)

Chronic Renal Failure

Taiwan
Children's Hospital Medical Center, Cincinnati
Patient-Centered Outcomes Research Institute

Enrolling by invitation

Garnering Effective Telehealth 2 Help Optimize Multidisciplinary Team Engagement (GET2HOME)

Children With Complex Chronic Conditions

United States
Parker Research Institute
VIA University College; University of Southern Denmark

Completed

A Better Everyday Life Among Persons With Chronic Conditions (ABLE)

Chronic Conditions, Multiple

Denmark
Assiut University

Not yet recruiting

Pericapsular Nerve Group Block Versus Lumber Erector Spinae Plane Block for Pain Management After Total Hip Arthroplasty

Post Operative Pain, Chronic
University of Colorado, Denver
Johns Hopkins University

Enrolling by invitation

Quality of Life Assessment of Chronic Pancreatitis Endoscopic Interventions (QOLAPI)

Chronic Pancreatitis

United States
Samuel Vilchez
National Autonomous University of Nicaragua; Ministerio de Salud de Nicaragua; GID BIO

Completed

CKDu Treated With Intra-arterial Infusion of Autologous SVF Cells

Chronic Renal Failure of Unknown Cause

Nicaragua
Lophius Biosciences GmbH

Completed

Validation of Lophius Kits T-Track® CMV and T-Track® EBV in Hemodialysis Patients

Renal Failure Chronic Requiring Dialysis
PharmaEssentia

Recruiting

The Safety and Efficacy of Sequential Treatment of Ropeginterferon Alfa-2b (P1101) and Anti-PD1 in Interferon-Naive Adults With Chronic Hepatitis B or D Infection

Chronic Hepatitis B Infection | Chronic Hepatitis D Infection

Taiwan
ECOG-ACRIN Cancer Research Group
National Cancer Institute (NCI)

Recruiting

Pembrolizumab and Dasatinib, Imatinib Mesylate, or Nilotinib in Treating Patients With Chronic Myeloid Leukemia and Persistently Detectable Minimal Residual Disease

Minimal Residual Disease | Chronic Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive

United States
Far Eastern Memorial Hospital

Active, not recruiting

The Life Style Patterns and the Development Trend of Chronic Diseases in Healthy and Sub-healthy Groups Were Analyzed by Using Data-mining Techniques

Metabolic Syndrome | Chronic Disease | Chronic Kidney Disease Stage 5 | Chronic Kidney Disease Stage 3 | Chronic Kidney Disease Stage 4 | Chronic Kidney Disease Stage 2 | Chronic Kidney Disease Stage 1

Taiwan
National Cancer Institute (NCI)

Completed

Imatinib Mesylate and Decitabine in Treating Patients With Chronic Myelogenous Leukemia

Accelerated Phase Chronic Myelogenous Leukemia | Childhood Chronic Myelogenous Leukemia | Relapsing Chronic Myelogenous Leukemia | Chronic Myelogenous Leukemia, BCR-ABL1 Positive | Blastic Phase Chronic Myelogenous Leukemia

United States
Chiesi Farmaceutici S.p.A.

Recruiting

A 52-week, Placebo-controlled Study to Evaluate the Efficacy and Safety of 2 Doses of CHF6001 DPI (Tanimilast), as add-on to Maintenance Triple Therapy in Subjects With COPD and Chronic Bronchitis (PILASTER) (PILASTER)

Chronic Obstructive Pulmonary Disease

Bulgaria, United States, Albania, Argentina, Australia, Austria, Bosnia and Herzegovina, Chile, China, Czechia, Georgia, Germany, Greece, Hungary, Israel, Italy, Mexico, Netherlands, New Zealand, North Macedonia, Poland, Romania, Russian... and more
University of North Carolina, Chapel Hill
Johns Hopkins University; National Heart, Lung, and Blood Institute (NHLBI); University... and other collaborators

Active, not recruiting

Study of COPD Subgroups and Biomarkers (SPIROMICS)

Chronic Obstructive Pulmonary Disease | Emphysema | COPD | Chronic Bronchitis

United States
Bristol-Myers Squibb
PPD; ICON Clinical Research; Q2 Solutions; Molecular MD; MultiPharma; Steering Committee and other collaborators

Completed

Study of Dasatinib vs Imatinib in Patients With Chronic Myeloid Leukemia (CML) Who Did Not Have Favorable Response to Imatinib (DASCERN)

Chronic Phase Chronic Myeloid Leukemia

Italy, Thailand, United States, Belgium, Czechia, Hungary, Argentina, Austria, Brazil, Canada, China, France, Korea, Republic of, Poland, Spain
University of Copenhagen
Stine Kristensen; Gita Krüger Mørch; Rizwan Butt; Ditte Hansen

Not yet recruiting

a Randomized Controlled Trial of the Intake of Organic and Inorganic Phosphate in Peritoneal Dialysis Patients (RCTOIP)

Chronic Kidney Disease Requiring Chronic Dialysis

Denmark
University of North Carolina, Chapel Hill
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); Duke... and other collaborators

Completed

Breaking Down Care Process and Patient-level Barriers to Arteriovenous Access Creation Prior to Hemodialysis Initiation

Chronic Kidney Disease | Chronic Kidney Disease Requiring Chronic Dialysis

United States
Pavol Jozef Safarik University
Dialysis Services Fresenius Medical Care Slovakia; Private Health Institution...

Completed

Intradialytic Resistance Training in Haemodialysis Patients (IRTHEP)

Chronic Kidney Disease Requiring Chronic Dialysis

Slovakia
McGill University Health Centre/Research Institute...

Completed

Intradialytic Pedalling Exercise and Vascular Hemodynamic Parameters Among Prevalent Hemodialysis Population

Chronic Kidney Disease Requiring Chronic Dialysis
Baxter Healthcare Corporation
Gambro Dialysatoren GmbH

Completed

Performance Comparison of Revaclear With Larger Dialyzer (Revacom HD)

Renal Failure Chronic Requiring Hemodialysis

Austria

Clinical Trials on Chronic Disabling

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Medical Conditions

Drug Interventions

CROs by country

CROs in Belgium

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Rare Diseases

Drug Interventions

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