Clinical Trials on Chronic Illness

Total 34624 results

Jiangsu Hansoh Pharmaceutical Co., Ltd.

Recruiting

A Study of Hansoh (HS)-10502 in Patients With Advanced Solid Tumors

Breast Cancer | Colorectal Cancer | Pancreatic Cancer | Ovarian Cancer | Prostatic Cancer

China
National Cancer Institute (NCI)

Recruiting

Testing the Combination of the Anti-Cancer Drugs Temozolomide and M1774 to Evaluate Their Safety and Effectiveness

Advanced Malignant Solid Neoplasm | Metastatic Malignant Solid Neoplasm | Stage IV Colorectal Cancer AJCC v8 | Stage III Colorectal Cancer AJCC v8 | Metastatic Microsatellite Stable Colorectal Carcinoma | Advanced Microsatellite Stable Colorectal Carcinoma | Hematopoietic and Lymphatic System...

United States
Seoul National University Hospital

Recruiting

Assessment of Quality of Life After Low Anterior Resection During Cytoreductive Surgery for Advanced Ovarian Cancer (LAPSODY)

Quality of Life | Ovarian Cancer | Low Anterior Resection Syndrome

Korea, Republic of
Revolution Medicines, Inc.

Recruiting

Study of RMC-6236 in Patients With Advanced Solid Tumors Harboring Specific Mutations in RAS

Advanced Solid Tumors | Non-small Cell Lung Cancer (NSCLC) | Pancreatic Ductal Adenocarcinoma (PDAC) | Colorectal Cancer (CRC)

United States
Novartis Pharmaceuticals

Recruiting

Platform Study of JDQ443 in Combinations in Patients With Advanced Solid Tumors Harboring the KRAS G12C Mutation (KontRASt-03)

Carcinoma, Non-Small-Cell Lung | Colorectal Neoplasms | Colorectal Cancer | Non-Small Cell Lung Cancer | Nonsmall Cell Lung Cancer | Carcinoma, Non-Small Cell Lung | Colorectal Tumors | Colorectal Carcinoma | Neoplasms, Colorectal | Non-Small Cell Lung Carcinoma | KRAS G12C Mutant Solid Tumors

Korea, Republic of, Spain, Belgium, United States, France, Germany, Italy, Singapore
National Cancer Institute (NCI)

Recruiting

Testing Obeticholic Acid for Familial Adenomatous Polyposis

Familial Adenomatous Polyposis | Colorectal Carcinoma | Attenuated Familial Adenomatous Polyposis | Duodenal Carcinoma

United States, Puerto Rico
University Health Network, Toronto

Recruiting

Personalized Patient Derived Xenograft (pPDX) Modeling to Test Drug Response in Matching Host (REFLECT)

Breast Cancer | Breast Neoplasms | Colorectal Neoplasms | Colorectal Cancer | Ovarian Cancer | Ovarian Neoplasm

Canada
Ohio State University
Pfizer; PTEN Research

Active, not recruiting

Sirolimus for Cowden Syndrome With Colon Polyposis

Cowden Syndrome | Polyposis | PTEN Gene Mutation | PTEN Hamartoma Tumor Syndrome | PTEN Hamartoma Syndrome | Bannayan Syndrome | Bannayan Zonana Syndrome

United States
Oncorus, Inc.
Merck Sharp & Dohme LLC

Terminated

Study of ONCR-177 Alone and in Combination With PD-1 Blockade in Adult Subjects With Advanced and/or Refractory Cutaneous, Subcutaneous or Metastatic Nodal Solid Tumors or With Liver Metastases of Solid Tumors

Melanoma | Cancer | Breast Cancer | Solid Tumor | Squamous Cell Carcinoma of Head and Neck | Triple Negative Breast Cancer | Advanced Solid Tumor | Liver Metastases | Colorectal Carcinoma | Non-melanoma Skin Cancer

United States, Canada
University Health Network, Toronto

Completed

Study of Azacitidine and Durvalumab in Advanced Solid Tumors (METADUR)

Microsatellite Stable Colorectal Carcinoma | Platinum Resistant Epithelial Ovarian Cancer Type II | Estrogen Receptor Positive and HER2 Negative Breast Cancer

Canada
National Cancer Institute (NCI)

Completed

Celecoxib With or Without Eflornithine in Preventing Colorectal Cancer in Patients With Familial Adenomatous Polyposis

Colorectal Cancer | Familial Adenomatous Polyposis

United States
Copenhagen University Hospital, Hvidovre

Completed

Endoscopic Evaluation of Duodenal Polyposis in Patients With Familial Adenomatous Polyposis (FAP)

Duodenal Cancer | Duodenal Polyposis | Familial Adenomatous Polyposes

Denmark
University of Wisconsin, Madison

Completed

Survivorship Care Plan in Promoting Physical Activity in Breast or Colorectal Cancer Survivors in Wisconsin

Cancer Survivor | Stage IIIA Breast Cancer | Stage IIIB Breast Cancer | Stage IA Breast Cancer | Stage IB Breast Cancer | Stage IIA Breast Cancer | Stage IIB Breast Cancer | Stage IIIC Breast Cancer | Healthy Subject | Stage I Colorectal Cancer | Stage IIIA Colorectal Cancer | Stage IIIB Colorectal Cancer | Stage... and other conditions

United States
Lei Li

Unknown

MSI in Circulatory DNA of Endometrial Cancer

Lynch Syndrome | Endometrial Cancer | Microsatellite Instability | Circulating Tumor Cell

China
Chinese University of Hong Kong

Completed

A Novel Robotic System for Single Port and Natural Orifice Transluminal Endoscopic Surgery

Urologic Neoplasms | Urologic Diseases | Nasopharyngeal Neoplasms | Colorectal Neoplasms | Oropharyngeal Neoplasms | Hypopharyngeal Neoplasms | Laryngeal Neoplasms | Oral Neoplasms | ENT Diseases

China
michal roll

Unknown

Erythromycin Treatment for Readthrough of APC Gene Stop Codon Mutation in Familial Adenomatous Polyposis-minors' Adjusted Version

FAP-Familial Adenomatous Polyposis
Radboud University Medical Center
Dutch Cancer Society

Completed

Prevention of Progression of Duodenal Adenomas in Patients With Familial Adenomatous Polyposis (PreDuoFAP)

Familial Adenomatous Polyposis | Duodenal Neoplasms | Duodenal Polyps

Netherlands
Stanford University
Caring for Carcinoid Foundation; GI Cancer Research Gift Fund

Withdrawn

Collection of Biospecimen & Clinical Information in Patients w/ Gastrointestinal Cancers

Gastrointestinal Neoplasms | Pancreatic Cancer | Anal Cancer | Colon/Rectal Cancer | Hepatobiliary Cancers | Gastric (Stomach) Cancer | Gynecologic Cancers | Gastro-Esophageal(GE) Junction Cancer | Gynecologic Cancers Cervical Cancer | Gastrointenstinal Stromal Tumor (GIST) | Colon/Rectal Cancer Colon Cancer and other conditions

United States
Academic and Community Cancer Research United
National Cancer Institute (NCI)

Active, not recruiting

Panitumumab, Regorafenib, or TAS-102, in Treating Patients With Metastatic and/or Unresectable RAS Wild-Type Colorectal Cancer

Metastatic Colon Adenocarcinoma | Metastatic Colorectal Carcinoma | Metastatic Rectal Adenocarcinoma | Stage III Colon Cancer AJCC v8 | Stage III Rectal Cancer AJCC v8 | Stage IIIA Colon Cancer AJCC v8 | Stage IIIA Rectal Cancer AJCC v8 | Stage IIIB Colon Cancer AJCC v8 | Stage IIIB Rectal Cancer AJCC... and other conditions

United States
DxTerity Diagnostics
National Cancer Institute (NCI)

Unknown

Radiotherapy Assessments During Intervention ANd Treatment (RADIANT) (RADIANT)

Cancer | Cancer of Liver | Cancer of Pancreas | Cancer of Stomach | Cancer of Cervix | Cancer of Colon | Cancer of Rectum | Cancer of Kidney and Renal Pelvis | Cancer of Prostate | Radiation Therapy | Cancer of Esophagus | Cancer of Ovary | Cancer of Kidney | Cancer of Bladder | Cancer of Gallbladder | Cancer of Anus | Cancer... and other conditions

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

LY3214996 and Cetuximab Alone or in Combination With Abemaciclib for the Treatment of Unresectable or Metastatic Colorectal Cancer

Recurrent Colorectal Carcinoma | Metastatic Colon Adenocarcinoma | Metastatic Colorectal Carcinoma | Metastatic Rectal Adenocarcinoma | Stage III Colon Cancer AJCC v8 | Stage III Rectal Cancer AJCC v8 | Stage IIIA Colon Cancer AJCC v8 | Stage IIIA Rectal Cancer AJCC v8 | Stage IIIB Colon Cancer AJCC v8 and other conditions

United States
AHS Cancer Control Alberta
EMD Serono

Active, not recruiting

Avelumab With Valproic Acid in Virus-associated Cancer (LATENT)

Squamous Cell Carcinoma of the Cervix | Cancer That is Associated With a Chronic Viral Infection | p16 Positive SCCHN | p16 Positive Squamous Cell Carcinoma of the Vagina or Vulva | p16 Positive Squamous Cell Carcinoma of the Penis | p16 Positive Squamous Cell Carcinoma of the Anus or Anal... and other conditions

Canada
Burke Medical Research Institute

Active, not recruiting

Home Based Tele-exercise for People With Chronic Neurological Impairments (Telex)

Stroke | Multiple Sclerosis | Cerebral Palsy | Parkinson Disease | Spinal Cord Injuries | Neurologic Disorder | Hemiplegia | Hemiparesis | Friedreich Ataxia | Trauma, Brain | Transverse Myelitis

United States
Rutgers, The State University of New Jersey
National Cancer Institute (NCI); Rutgers Cancer Institute of New Jersey

Terminated

Lactobacillus in Preventing Infection in Patients Undergoing a Donor Stem Cell Transplant for Hematologic Cancer or Myelodysplastic Syndrome

Lymphoma | Myelodysplastic Syndromes | Leukemia | Testicular Germ Cell Tumor | Breast Cancer | Chronic Myeloproliferative Disorders | Ovarian Cancer | Neuroblastoma | Multiple Myeloma and Plasma Cell Neoplasm | Myelodysplastic/Myeloproliferative Neoplasms

United States
Indiana University School of Medicine
National Cancer Institute (NCI)

Completed

Interleukin-12 in Treating Patients With Hematologic Cancers or Solid Tumors

Lymphoma | Kidney Cancer | Myelodysplastic Syndromes | Leukemia | Testicular Germ Cell Tumor | Breast Cancer | Chronic Myeloproliferative Disorders | Ovarian Cancer | Gestational Trophoblastic Tumor | Neuroblastoma | Multiple Myeloma and Plasma Cell Neoplasm

United States
Medical College of Wisconsin

Unknown

Light-Emitting Diode Therapy in Preventing Mucositis in Children Receiving Chemotherapy With or Without Radiation Therapy Before Bone Marrow Transplantation

Sarcoma | Pain | Lymphoma | Kidney Cancer | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Ovarian Cancer | Neuroblastoma | Multiple Myeloma and Plasma Cell Neoplasm | Oral Complications | Myelodysplastic/Myeloproliferative Neoplasms

United States
Cancer Treatment Centers of America

Completed

Biological Therapy Following Chemotherapy and Peripheral Stem Cell Transplantation in Treating Patients With Cancer

Sarcoma | Lymphoma | Kidney Cancer | Myelodysplastic Syndromes | Leukemia | Testicular Germ Cell Tumor | Breast Cancer | Chronic Myeloproliferative Disorders | Ovarian Cancer | Gestational Trophoblastic Tumor | Neuroblastoma | Multiple Myeloma and Plasma Cell Neoplasm

United States
Universitätsklinikum Hamburg-Eppendorf

Recruiting

Cold Atmospheric Plasma for the Endoscopic Treatment of Duodenal Polyps in Patients With Familial Adenomatous Polyposis (coldAPC)

Familial Adenomatous Polyposis | Adenomatous Polyposis Coli | Duodenal Adenoma

Germany
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Not yet recruiting

Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics (COSMIC)

Melanoma | Non-Hodgkin Lymphoma | Breast Carcinoma | Lung Non-Small Cell Carcinoma | Colorectal Carcinoma
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Fecal Microbiota Transplantation in Treating Immune-Checkpoint Inhibitor Induced-Diarrhea or Colitis in Genitourinary Cancer Patients

Melanoma | Cervical Cancer | Breast Cancer | Diarrhea | Ovarian Cancer | Lung Cancer | Colitis | Uterine Cancer | Malignant Genitourinary System Neoplasm

United States
Western Sydney Local Health District

Recruiting

Cold Snare Polypectomy for Duodenal Adenomas in Familial Adenomatous Polyposis (COPDA)

Familial Adenomatous Polyposis

Australia
Medical University of Vienna

Recruiting

Establishment of a Tumor Bank for Blood Samples

Endocrine Gland Neoplasms | Breast Neoplasms | Lung Neoplasms | Colorectal Neoplasms | Ovarian Neoplasms | Neoplasms of the Female Genitalia

Austria, Germany, Italy, Belgium
Bolt Biotherapeutics, Inc.
Bristol-Myers Squibb

Active, not recruiting

A First-in-human Study Using BDC-1001 as a Single Agent and in Combination With Nivolumab in Advanced HER2-Expressing Solid Tumors

HER2-positive Breast Cancer | HER2-positive Colorectal Cancer | HER2-positive Solid Tumors | HER2-positive Gastroesophageal Cancer | HER2-positive Endometrial Cancer

France, United States, Spain, Korea, Republic of, Italy
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Weight Management and Health Behavior Intervention in Lowering Cancer Risk for BRCA Positive and Lynch Syndrome Families

Lynch Syndrome | Hereditary Breast Carcinoma | Hereditary Ovarian Carcinoma

United States
Kaiser Permanente
Patient-Centered Outcomes Research Institute

Active, not recruiting

Family History Study on Cancer Risk

Breast Cancer | Colorectal Cancer | Ovarian Cancer | Lynch Syndrome | Genetic Predisposition | Family Characteristics

United States
University of Pittsburgh
National Cancer Institute (NCI)

Completed

Comprehensive Electronic Cancer Support System for the Treatment of Cancer Related Symptoms (CaSSY)

Hepatocellular Carcinoma | Pancreatic Cancer | Primary Liver Cancer | Bile Duct Cancer | Liver Metastases | Colorectal Carcinoma | Gallbladder Cancer

United States
Vanderbilt University Medical Center

Completed

Pain Outcomes Following Intralesional Corticosteroid Injections

Plaque Psoriasis | Morphea | Alopecia Areata | Acne | Lichen Planus | Keloid | Prurigo Nodularis | Hypertrophic Scar | Frontal Fibrosing Alopecia | Keratoacanthoma | Granuloma Annulare | Nummular Eczema | Lichen Simplex Chronicus | Lichen Plano-Pilaris | Epidermal Inclusion Cyst

United States
National Cancer Institute (NCI)

Withdrawn

Clinical Sequencing of Cancer and Tissue Repository: OncoGenomics

Neoplasms | Myelodysplastic Syndromes | Adenomatous Polyposis Coli | Neurofibroma, Plexiform

United States
Merrimack Pharmaceuticals
Sanofi

Completed

A Safety Study of MM-121 With Cetuximab and Irinotecan in Patients With Advanced Cancers

Colorectal Cancer | Triple Negative Breast Cancer | Non-small Cell Lung Cancer | Squamous Cell Head and Neck Cancer | Other Tumors With EGFR Dependence

United States
Pfizer

Terminated

Observational Familial Adenomatous Polyposis Registry Study In Patients Receiving Celecoxib Compared to Control Patients

Familial Adenomatous Polyposis (FAP)

United States, Spain, Canada, Denmark
Revolution Medicines, Inc.

Recruiting

Study of RMC-9805 in Participants With KRASG12D-Mutant Solid Tumors

Advanced Solid Tumors | Non-small Cell Lung Cancer (NSCLC) | Pancreatic Ductal Adenocarcinoma (PDAC) | Colorectal Cancer (CRC)

United States
Lyell Immunopharma, Inc.

Recruiting

A Study to Investigate LYL845 in Adults With Solid Tumors

Melanoma | Colorectal Cancer | Non-small Cell Lung Cancer

United States
Gynecologic Oncology Group
National Cancer Institute (NCI)

Not yet recruiting

Biomarkers in Samples From Patients With Endometrial Cancer

Lynch Syndrome | Recurrent Uterine Corpus Carcinoma | Stage I Uterine Corpus Cancer | Stage II Uterine Corpus Cancer | Stage III Uterine Corpus Cancer | Stage IV Uterine Corpus Cancer

United States
Sidney Kimmel Cancer Center at Thomas Jefferson...
United States Department of Defense

Active, not recruiting

Linaclotide in Treating Patients With Stages 0-3 Colorectal Cancer

Colorectal Adenoma | Stage III Colorectal Cancer AJCC v8 | Stage IIIA Colorectal Cancer AJCC v8 | Stage IIIB Colorectal Cancer AJCC v8 | Stage IIIC Colorectal Cancer AJCC v8 | Stage 0 Colorectal Cancer AJCC v8 | Stage I Colorectal Cancer AJCC v8 | Stage II Colorectal Cancer AJCC v8 | Stage IIA Colorectal... and other conditions

United States
M.D. Anderson Cancer Center

Completed

Non-Surgical Management of Attenuated and Deleterious (Classical) Familial Adenomatous Polyposis: A Long-term Surveillance Program

Attenuated Familial Adenomatous Polyposis | Deleterious Familial Adenomatous Polyposis

United States
National Cancer Institute (NCI)

Completed

Erlotinib Hydrochloride in Reducing Duodenal Polyp Burden in Patients With Familial Adenomatous Polyposis at Risk of Developing Colon Cancer

Familial Adenomatous Polyposis | Attenuated Familial Adenomatous Polyposis

United States, Puerto Rico
Roswell Park Cancer Institute
Merck Sharp & Dohme LLC

Withdrawn

Rintatolimod and Pembrolizumab for the Treatment of Refractory Metastatic or Unresectable Colorectal Cancer

Metastatic Colorectal Adenocarcinoma | Refractory Colorectal Adenocarcinoma | Microsatellite Stable | Stage IV Colorectal Cancer AJCC v8 | Stage IVA Colorectal Cancer AJCC v8 | Stage IVB Colorectal Cancer AJCC v8 | Stage IVC Colorectal Cancer AJCC v8 | Stage III Colorectal Cancer AJCC v8 | Stage IIIA... and other conditions

United States
Ain Shams University

Unknown

Effect of Vitamin d Deficiency in Chronic Rhinosinusitis With Nasal Polyposis

Vitamin D Deficiency, Nasal Polyposis

Egypt
AbbVie

Completed

Impact of AbbVie Care Patient Support Program on Clinical, Health Economic and Patient Reported Outcomes, in Crohn's Disease, Ulcerative Colitis, Rheumatoid Arthritis, Psoriatic Arthritis, Psoriasis and Axial Spondyloarthritis, in the Portuguese National Health Service (IMPROVE)

Psoriasis | Crohn's Disease | Psoriatic Arthritis | Rheumatoid Arthritis (RA) | Non-radiographic Axial Spondyloarthritis | Ulcerative Colitis (UC) | Ankylosing Spondylitis (AS)

Portugal
Tel-Aviv Sourasky Medical Center

Unknown

Turmeric Supplementation on Polyp Number and Size in Patients With Familial Adenomatous Polyposis.

Familial Adenomatous Polyposis | FAP | FAP Gene Mutation

Clinical Trials on Chronic Illness

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Norway

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations