Clinical Trials on Chronic Knee Osteoarthritis

Total 39257 results

Revolution Medicines, Inc.

Recruiting

Study of RMC-6291 in Combination With RMC-6236 in Participants With Advanced KRAS G12C Mutant Solid Tumors

Colorectal Cancer | Pancreatic Ductal Adenocarcinoma | Non-Small Cell Lung Cancer (NSCLC)

United States, Puerto Rico
Merck Sharp & Dohme LLC

Recruiting

Pembrolizumab Plus Lenvatinib in Combination With Belzutifan in Solid Tumors (MK-6482-016)

Carcinoma, Hepatocellular | Colorectal Neoplasms | Esophageal Neoplasms | Endometrial Neoplasms | Pancreatic Ductal Adenocarcinoma | Biliary Tract Neoplasms

Israel, United States, Australia, Belgium, Chile, France, Korea, Republic of, Netherlands, Spain, New Zealand
Novartis Pharmaceuticals

Recruiting

Study of JDQ443 in Patients With Advanced Solid Tumors Harboring the KRAS G12C Mutation (KontRASt-01)

Carcinoma, Non-Small-Cell Lung | Lung Cancer | Neoplasms, Lung | Pulmonary Neoplasms | Neoplasms, Pulmonary | Pulmonary Cancer | Cancer of Lung | Cancer of the Lung | KRAS G12C Mutant Solid Tumors | Carcinoma, Colorectal

United States, Japan, Australia, Germany, Italy, Spain, Canada, Denmark, Korea, Republic of, Taiwan, Belgium, Hong Kong, China, France, Singapore, Netherlands
Academisch Medisch Centrum - Universiteit van Amsterdam...
IRCCS Azienda Ospedaliero-Universitaria di Bologna; Hospital Clinic of Barcelona and other collaborators

Recruiting

A Personalized Surveillance and Intervention Protocol for Duodenal and Gastric Polyposis in Patients With Familial Adenomatous Polyposis

Familial Adenomatous Polyposis

Netherlands
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Personalized Peptide Vaccine in Treating Patients With Advanced Pancreatic Cancer or Colorectal Cancer

Stage IV Pancreatic Cancer AJCC v6 and v7 | Metastatic Colorectal Adenocarcinoma | Stage IV Colorectal Cancer AJCC v7 | Stage IVA Colorectal Cancer AJCC v7 | Stage IVB Colorectal Cancer AJCC v7 | Metastatic Pancreatic Ductal Adenocarcinoma

United States
Oslo University Hospital
The Research Council of Norway

Recruiting

Peritoneal Surface Malignancies - Characterization, Models and Treatment Strategies (PSM)

Mesothelioma | Pseudomyxoma Peritonei | Colorectal Carcinoma | Ovarian Carcinoma

Norway
Medical University of Vienna

Recruiting

Establishment of a Tumor Bank for Tissue Samples

Endocrine Gland Neoplasms | Breast Neoplasms | Lung Neoplasms | Colorectal Neoplasms | Ovarian Neoplasms | Neoplasms of the Female Genitalia

Austria, Germany, Belgium
S.L.A. Pharma AG

Active, not recruiting

Effect of EPA-FFA on Polypectomy in Familial Adenomatous Polyposis

Familial Adenomatous Polyposis

Italy
City of Hope Medical Center
National Cancer Institute (NCI)

Active, not recruiting

HOPE-Genomics Intervention for the Improvement of Cancer Patient Knowledge of Genomics

Malignant Solid Neoplasm | Breast Carcinoma | Lung Carcinoma | Colorectal Carcinoma | Ovarian Carcinoma | Pancreatic Carcinoma | Prostate Carcinoma

United States
The Canadian College of Naturopathic Medicine
Bastyr University; Lotte & John Hecht Memorial Foundation

Completed

The Canadian/US Integrative Oncology Study (CUSIOS)

Breast Neoplasms | Colorectal Neoplasms | Pancreatic Neoplasms | Ovarian Neoplasms

United States, Canada
Rapamycin Holdings, Inc. dba Emtora Biosciences
LumaBridge

Active, not recruiting

Trial of eRapa to Prevent Progression in Familial Adenomatous Polyposis Patients Under Active Surveillance

Familial Adenomatous Polyposis

United States
Silverback Therapeutics

Terminated

A Safety and Activity Study of SBT6050 in Combination With Other HER2-directed Therapies for HER2-positive Cancers

HER2-positive Breast Cancer | HER2-positive Gastric Cancer | HER2-positive Colorectal Cancer | HER2-expressing Non-small Cell Lung Cancer

United States
Stony Brook University
Karius, Inc.

Completed

Next Generation Sequencing Detection of Lyme Disease

Lyme Disease | Lyme Arthritis | Pediatric Infectious Disease | Erythema Migrans | Lyme Carditis | Lyme Disease Meningitis

United States
University of Puerto Rico
National Institutes of Health (NIH)

Completed

Use of Curcumin for Treatment of Intestinal Adenomas in Familial Adenomatous Polyposis (FAP)

Familial Adenomatous Polyposis

Puerto Rico
University of Southern California
National Cancer Institute (NCI)

Withdrawn

Nutritional Preferences and Product Accessibility in Oral Nutritional Supplements in Participants With Breast, Colorectal, Upper Gastrointestinal, or Prostate Cancer

Cholangiocarcinoma | Breast Carcinoma | Gastric Carcinoma | Colorectal Carcinoma | Pancreatic Carcinoma | Prostate Carcinoma | Malignant Digestive System Neoplasm

United States
Vanderbilt-Ingram Cancer Center
National Cancer Institute (NCI)

Terminated

18F-FES PET/CT in Imaging Patients With Desmoid Tumors

Familial Adenomatous Polyposis | Deep Fibromatosis/Desmoid Tumor

United States
Academisch Medisch Centrum - Universiteit van Amsterdam...

Completed

Sirolimus and Familial Adenomatous Polyposis (FAP)

Adenomatous Polyposis Coli

Netherlands
AbbVie
Raffeiner GmbH

Completed

Assessment of Rheumatoid Arthritis, Psoriatic Arthritis, Ankylosing Spondylitis, Plaque Psoriasis, Crohn's Disease and Ulcerative Colitis Patients´ Adherence Attitudes to Maintenance Therapy With a Scheduled Adalimumab Treatment in Routine Clinical Practice (Adherence)

Rheumatoid Arthritis | Plaque Psoriasis | Ulcerative Colitis | Psoriatic Arthritis | Ankylosing Spondylitis | Crohn´s Disease
Rabin Medical Center

Unknown

Prostate Cancer Screening Among Men With High Risk Genetic Predisposition

Lynch Syndrome | BRCA1 Syndrome | BRCA2 Syndrome

Israel
National Cancer Institute (NCI)

Completed

Curcumin in Treating Patients With Familial Adenomatous Polyposis

Familial Adenomatous Polyposis

United States, Puerto Rico
The Cleveland Clinic
Ohio State University Comprehensive Cancer Center

Completed

Lyophilized Black Raspberries in Adults With Familial Adenomatous Polyposis (FAP)

Familial Adenomatous Polyposis

United States
Henry Ford Health System
Schering-Plough

Completed

Association Between Hepatitis C Infection and Renal Cell Carcinoma

Renal Cell Carcinoma | Hepatitis C | Colorectal Cancer

United States
Centre Oscar Lambret
Roche Pharma AG

Completed

Study About Preventive Treatment of Folliculitis Induced by Epidermal Growth Factor Receptor Inhibitors (DIPROCOL)

Metastatic Colorectal Cancer | Non-Small-Cell Lung Carcinoma

France
Radboud University Medical Center
Dutch Cancer Society

Unknown

Influence of Sulindac and Probiotics on the Development of Pouch Adenomas in Patients With Familial Adenomatous Polyposis

Adenomatous Polyposis Coli

Netherlands
Aronex Pharmaceuticals

Unknown

A Safety and Effectiveness Study of Aroplatin in Patients With Advanced Solid Malignancies

Neoplasms | Colorectal Neoplasms | Hepatocellular Carcinoma | Pancreatic Neoplasms | Esophageal Neoplasms | Ovarian Neoplasms

United States
National Cancer Institute (NCI)

Terminated

17-N-Allylamino-17-Demethoxygeldanamycin and Bortezomib in Treating Patients With Relapsed or Refractory Hematologic Cancer

Recurrent Adult Acute Myeloid Leukemia | Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Grade 1 Follicular Lymphoma | Recurrent Grade 2 Follicular Lymphoma | Recurrent... and other conditions

United States
National Cancer Institute (NCI)

Terminated

Radiolabeled Monoclonal Antibody Plus Rituximab With and Without Filgrastim and Interleukin-11 in Treating Patients With Relapsed or Refractory Non-Hodgkin's Lymphoma

Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue | Nodal Marginal Zone B-cell Lymphoma | Recurrent Grade 1 Follicular Lymphoma | Recurrent Grade 2 Follicular Lymphoma | Recurrent Grade 3 Follicular Lymphoma | Recurrent Marginal Zone Lymphoma | Splenic Marginal Zone... and other conditions

United States
Brigham and Women's Hospital
Agency for Healthcare Research and Quality (AHRQ)

Completed

Improving Safety of Diagnosis and Therapy in the Inpatient Setting (PSLL2-0)

Pneumonia | Sepsis | Delirium | Confusion | Hip Pain Chronic | Hypoxia | Back Pain | Vomiting | Abdominal Pain | Diarrhea | Cough | Asthma | Chest Pain | Neck Pain | Fever | Cellulitis | Syncope | Headache | Deep Vein Thrombosis | Venous Thromboembolism | Soft Tissue Infections | Failure to Thrive | COPD | Pulmonary Embolism | Dyspnea | Leg Pain | Mental... and other conditions

United States
Rutgers, The State University of New Jersey
National Cancer Institute (NCI); Rutgers Cancer Institute of New Jersey

Withdrawn

Perceptions of Burden in Patients With Late-Stage Cancer and Their Caregivers

Depression | Lymphoma | Myelodysplastic Syndromes | Leukemia | Chronic Myeloproliferative Disorders | Brain and Central Nervous System Tumors | Unspecified Adult Solid Tumor, Protocol Specific | Multiple Myeloma and Plasma Cell Neoplasm | Psychosocial Effects of Cancer and Its Treatment | Myelodysplastic...
Vanderbilt University
National Cancer Institute (NCI)

Terminated

Presence of Donor-Derived DNA in Semen Samples From Cancer Survivors Who Underwent Donor Stem Cell Transplant

Lymphoma | Myelodysplastic Syndromes | Leukemia | Testicular Germ Cell Tumor | Chronic Myeloproliferative Disorders | Cancer Survivor | Neuroblastoma | Multiple Myeloma and Plasma Cell Neoplasm | Myelodysplastic/Myeloproliferative Neoplasms

United States
Academic and Community Cancer Research United
National Cancer Institute (NCI)

Active, not recruiting

Panitumumab, Regorafenib, or TAS-102, in Treating Patients With Metastatic and/or Unresectable RAS Wild-Type Colorectal Cancer

Metastatic Colon Adenocarcinoma | Metastatic Colorectal Carcinoma | Metastatic Rectal Adenocarcinoma | Stage III Colon Cancer AJCC v8 | Stage III Rectal Cancer AJCC v8 | Stage IIIA Colon Cancer AJCC v8 | Stage IIIA Rectal Cancer AJCC v8 | Stage IIIB Colon Cancer AJCC v8 | Stage IIIB Rectal Cancer AJCC... and other conditions

United States
DxTerity Diagnostics
National Cancer Institute (NCI)

Unknown

Radiotherapy Assessments During Intervention ANd Treatment (RADIANT) (RADIANT)

Cancer | Cancer of Liver | Cancer of Pancreas | Cancer of Stomach | Cancer of Cervix | Cancer of Colon | Cancer of Rectum | Cancer of Kidney and Renal Pelvis | Cancer of Prostate | Radiation Therapy | Cancer of Esophagus | Cancer of Ovary | Cancer of Kidney | Cancer of Bladder | Cancer of Gallbladder | Cancer of Anus | Cancer... and other conditions

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

LY3214996 and Cetuximab Alone or in Combination With Abemaciclib for the Treatment of Unresectable or Metastatic Colorectal Cancer

Recurrent Colorectal Carcinoma | Metastatic Colon Adenocarcinoma | Metastatic Colorectal Carcinoma | Metastatic Rectal Adenocarcinoma | Stage III Colon Cancer AJCC v8 | Stage III Rectal Cancer AJCC v8 | Stage IIIA Colon Cancer AJCC v8 | Stage IIIA Rectal Cancer AJCC v8 | Stage IIIB Colon Cancer AJCC v8 and other conditions

United States
Wake Forest University Health Sciences

Completed

Quality of Life and Survivorship Care in Patients Undergoing Hyperthermic Intraperitoneal Chemotherapy (HIPEC) (HOPE)

Unspecified Childhood Solid Tumor, Protocol Specific | Pseudomyxoma Peritonei | Stage IV Ovarian Epithelial Cancer | Stage IV Ovarian Germ Cell Tumor | Ovarian Sarcoma | Recurrent Ovarian Epithelial Cancer | Stage IV Colon Cancer | Recurrent Colon Cancer | Carcinoma of the Appendix | Ovarian Stromal Cancer and other conditions

United States
Universitätsklinikum Hamburg-Eppendorf

Recruiting

Cold Atmospheric Plasma for the Endoscopic Treatment of Duodenal Polyps in Patients With Familial Adenomatous Polyposis (coldAPC)

Familial Adenomatous Polyposis | Adenomatous Polyposis Coli | Duodenal Adenoma

Germany
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Not yet recruiting

Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics (COSMIC)

Melanoma | Non-Hodgkin Lymphoma | Breast Carcinoma | Lung Non-Small Cell Carcinoma | Colorectal Carcinoma
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Fecal Microbiota Transplantation in Treating Immune-Checkpoint Inhibitor Induced-Diarrhea or Colitis in Genitourinary Cancer Patients

Melanoma | Cervical Cancer | Breast Cancer | Diarrhea | Ovarian Cancer | Lung Cancer | Colitis | Uterine Cancer | Malignant Genitourinary System Neoplasm

United States
Western Sydney Local Health District

Recruiting

Cold Snare Polypectomy for Duodenal Adenomas in Familial Adenomatous Polyposis (COPDA)

Familial Adenomatous Polyposis

Australia
Medical University of Vienna

Recruiting

Establishment of a Tumor Bank for Blood Samples

Endocrine Gland Neoplasms | Breast Neoplasms | Lung Neoplasms | Colorectal Neoplasms | Ovarian Neoplasms | Neoplasms of the Female Genitalia

Austria, Germany, Italy, Belgium
Bolt Biotherapeutics, Inc.
Bristol-Myers Squibb

Active, not recruiting

A First-in-human Study Using BDC-1001 as a Single Agent and in Combination With Nivolumab in Advanced HER2-Expressing Solid Tumors

HER2-positive Breast Cancer | HER2-positive Colorectal Cancer | HER2-positive Solid Tumors | HER2-positive Gastroesophageal Cancer | HER2-positive Endometrial Cancer

France, United States, Spain, Korea, Republic of, Italy
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Weight Management and Health Behavior Intervention in Lowering Cancer Risk for BRCA Positive and Lynch Syndrome Families

Lynch Syndrome | Hereditary Breast Carcinoma | Hereditary Ovarian Carcinoma

United States
Kaiser Permanente
Patient-Centered Outcomes Research Institute

Active, not recruiting

Family History Study on Cancer Risk

Breast Cancer | Colorectal Cancer | Ovarian Cancer | Lynch Syndrome | Genetic Predisposition | Family Characteristics

United States
University of Pittsburgh
National Cancer Institute (NCI)

Completed

Comprehensive Electronic Cancer Support System for the Treatment of Cancer Related Symptoms (CaSSY)

Hepatocellular Carcinoma | Pancreatic Cancer | Primary Liver Cancer | Bile Duct Cancer | Liver Metastases | Colorectal Carcinoma | Gallbladder Cancer

United States
Vanderbilt University Medical Center

Completed

Pain Outcomes Following Intralesional Corticosteroid Injections

Plaque Psoriasis | Morphea | Alopecia Areata | Acne | Lichen Planus | Keloid | Prurigo Nodularis | Hypertrophic Scar | Frontal Fibrosing Alopecia | Keratoacanthoma | Granuloma Annulare | Nummular Eczema | Lichen Simplex Chronicus | Lichen Plano-Pilaris | Epidermal Inclusion Cyst

United States
National Cancer Institute (NCI)

Withdrawn

Clinical Sequencing of Cancer and Tissue Repository: OncoGenomics

Neoplasms | Myelodysplastic Syndromes | Adenomatous Polyposis Coli | Neurofibroma, Plexiform

United States
Merrimack Pharmaceuticals
Sanofi

Completed

A Safety Study of MM-121 With Cetuximab and Irinotecan in Patients With Advanced Cancers

Colorectal Cancer | Triple Negative Breast Cancer | Non-small Cell Lung Cancer | Squamous Cell Head and Neck Cancer | Other Tumors With EGFR Dependence

United States
Pfizer

Terminated

Observational Familial Adenomatous Polyposis Registry Study In Patients Receiving Celecoxib Compared to Control Patients

Familial Adenomatous Polyposis (FAP)

United States, Spain, Canada, Denmark
Revolution Medicines, Inc.

Recruiting

Study of RMC-9805 in Participants With KRASG12D-Mutant Solid Tumors

Advanced Solid Tumors | Non-small Cell Lung Cancer (NSCLC) | Pancreatic Ductal Adenocarcinoma (PDAC) | Colorectal Cancer (CRC)

United States
Lyell Immunopharma, Inc.

Recruiting

A Study to Investigate LYL845 in Adults With Solid Tumors

Melanoma | Colorectal Cancer | Non-small Cell Lung Cancer

United States
Gynecologic Oncology Group
National Cancer Institute (NCI)

Not yet recruiting

Biomarkers in Samples From Patients With Endometrial Cancer

Lynch Syndrome | Recurrent Uterine Corpus Carcinoma | Stage I Uterine Corpus Cancer | Stage II Uterine Corpus Cancer | Stage III Uterine Corpus Cancer | Stage IV Uterine Corpus Cancer

United States

Clinical Trials on Chronic Knee Osteoarthritis

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Bulgaria

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations