Clinical Trials on Circulating Tumor Cell

Total 40138 results

Mandos LLC

Terminated

Open-label Study of VTS-270 in Participants With Neurologic Manifestations of Niemann-Pick Type C1

Niemann-Pick Disease, Type C

Costa Rica
National Cancer Institute (NCI)

Completed

M7824 in Subjects With HPV Associated Malignancies

Cervical Cancer | Anal Cancer | Oropharyngeal Cancer | Human Papilloma Virus | Vaginal or Penile Cancer

United States
The Hospital for Sick Children

Active, not recruiting

International Rare Histiocytic Disorders Registry (IRHDR) (IRHDR)

Rare Histiocytic Disorders (RHDs) | Juvenile Xanthogranuloma (JXG) | Reticulohistiocytoma (Epithelioid Histiocytoma) | Xanthoma Disseminatum (XD) | Multicentric Reticulohistiocytosis (MRH) | Systemic Juvenile Xanthogranuloma | Erdheim-Chester Disease (ECD) | Multi-system Rosai-Dorfman Disease (RDD)

Canada, United States, Poland, Argentina, Austria, Czechia, Germany, Italy, Russian Federation, Spain
National Cancer Institute (NCI)

Terminated

Tocilizumab for Patients With Cancer and COVID-19 Disease

Hematopoietic and Lymphoid Cell Neoplasm | Malignant Solid Neoplasm | Pneumonia | Symptomatic COVID-19 Infection Laboratory-Confirmed | Severe Acute Respiratory Distress Syndrome | Pneumonitis

United States
National Cancer Institute (NCI)

Terminated

Amatuximab for High Mesothelin Cancers

Carcinoma, Non-Small-Cell Lung | Ovarian Neoplasms | Mesothelioma | Carcinoma, Pancreatic Ductal

United States
National Eye Institute (NEI)

Completed

Saccadic Eye Movements in Patients With Niemann-Pick Type C Disease

Niemann Pick Diseases

United States, United Kingdom
University of California, San Francisco
Johns Hopkins All Children's Hospital

Completed

A Study of Withdrawal of Immunosuppression and Donor Lymphocyte Infusions Following Allogeneic Transplant for Pediatric Hematologic Malignancies

Acute Myeloid Leukemia | Myelodysplastic Syndromes | Juvenile Myelomonocytic Leukemia | Acute Lymphoblastic Leukemia | Acute Leukemia | Chronic Myelogenous Leukemia | Biphenotypic Leukemia | Pre-leukemic Syndromes | Monosomy 7 | Bone Marrow Clonal Malformations

United States
St. Jude Children's Research Hospital

Completed

Stem Cell Transplantation for Patients With Hematologic Malignancies

Juvenile Myelomonocytic Leukemia | Non-Hodgkin Lymphoma | Chronic Myeloid Leukemia | Myelodysplastic Syndrome | Acute Lymphoblastic Leukemias | Acute Myelocytic Leukemia | Hemoglobinuria, Paroxysmal

United States
St. Jude Children's Research Hospital

Completed

Stem Cell Transplantation as Immunotherapy for Hematologic Malignancies

Acute Myeloid Leukemia | Leukemia | Hodgkin's Lymphoma | Juvenile Myelomonocytic Leukemia | Acute Lymphoblastic Leukemia | Non-Hodgkin Lymphoma | Chronic Myeloid Leukemia | Myelodysplastic Syndrome | Paroxysmal Nocturnal Hemoglobinuria

United States
UMC Utrecht
Dutch Health Care Insurance Board

Completed

Prevention of Glucocorticoid-Induced Osteoporosis in Rheumatic Diseases: Alendronate Versus Alfacalcidol.

Rheumatoid Arthritis | Polymyositis | Giant Cell Arteritis | Polymyalgia Rheumatica | Wegener's Granulomatosis

Netherlands
Dr. Danielle Vicus

Recruiting

Screening for Anal Cancer in Women With High-grade Vulvar Dysplasia or Vulvar Cancer. (Vulvar-AIN)

Cervical Cancer | Vulvar Cancer | Anal Cancer | Cervical Dysplasia | HPV-Related Anal Squamous Cell Carcinoma | Anal Dysplasia | Vulvar Dysplasia

Canada
City of Hope Medical Center
National Cancer Institute (NCI)

Active, not recruiting

Clofarabine and Melphalan Before Donor Stem Cell Transplant in Treating Patients With Myelodysplasia, Acute Leukemia in Remission, or Chronic Myelomonocytic Leukemia

Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome | Chronic Myelomonocytic Leukemia | Adult Acute Myeloid Leukemia in Remission | Myelodysplastic Syndrome | Adult Acute Lymphoblastic Leukemia in Remission | Therapy-Related Myelodysplastic Syndrome | Secondary Myelodysplastic...

United States
Blueprint Medicines Corporation

Active, not recruiting

(Concerto) Study of BLU-451 in Advanced Cancers With EGFR Exon 20 Insertion Mutations

Neoplasms | Neoplasms by Histologic Type | Lung Diseases | Neoplasms by Site | Adenocarcinoma | Carcinoma | Carcinoma, Non-Small-Cell Lung | Respiratory Tract Neoplasms | Carcinoma, Bronchogenic | Bronchial Neoplasms | Metastatic Lung Cancer | Antineoplastic Agents | Brain Metastases | Lung Neoplasm Malignant | EGFR... and other conditions

United States, Canada, Korea, Republic of, Japan, Taiwan
Seagen Inc.

Active, not recruiting

Basket Study of Tucatinib and Trastuzumab in Solid Tumors With HER2 Alterations

Urologic Neoplasms | Uterine Cervical Neoplasms | Uterine Neoplasms | Carcinoma, Non-Small-Cell Lung | Biliary Tract Neoplasms | HER2 Mutations Breast Neoplasms

United States, United Kingdom, Spain, Korea, Republic of, Italy, Belgium, Germany, Japan, Netherlands, Poland
Actelion

Completed

Safety and Efficacy of Miglustat in Chinese NPC Patients

Niemann-Pick Disease, Type C

China
Salome Kristensen

Terminated

COVID-19 Infection in Vulnerable Patients With Inflammatory Rheumatic Diseases

Rheumatoid Arthritis | Systemic Lupus Erythematosus | Giant Cell Arteritis | Psoriatic Arthritis | Axial Spondyloarthritis

Denmark
Vtesse, LLC, a Mallinckrodt Pharmaceuticals Company

Withdrawn

Safety and Tolerability Study of VTS-270 in Pediatric Participants With Niemann-Pick Type C (NPC) Disease

Niemann-Pick Disease, Type C
Barts & The London NHS Trust
Royal Marsden NHS Foundation Trust; Guy's and St Thomas' NHS Foundation Trust; Case Western Reserve University and other collaborators

Completed

Diagnostic Accuracy of MRI, DWI MRI, FDG-PET/CT and FEC PET/CT in the Detection of Lymph Node Metastases in Surgically Staged Endometrial and Cervical Carcinoma (MAPPING)

Endometrial Cancer | Surgically Staged Endometrial and Cervical Carcinoma | Cervical Cancer: Invasive Disease, FIGO Stage 1B1 or Higher | Stage 1A With Myometrial Invasion or Any Higher Stage and Grade 3 | Stage 1A With Myometrial Invasion or Any Other Higher Stage and Serous Papillary or... and other conditions

United Kingdom
Gynecologic Oncology Group
National Cancer Institute (NCI)

Completed

EGEN-001 and Pegylated Liposomal Doxorubicin Hydrochloride in Treating Patients With Recurrent or Persistent Ovarian Epithelial Cancer, Fallopian Tube Cancer, or Primary Peritoneal Cancer

Recurrent Fallopian Tube Carcinoma | Recurrent Ovarian Carcinoma | Recurrent Primary Peritoneal Carcinoma | Ovarian Clear Cell Cystadenocarcinoma | Ovarian Endometrioid Adenocarcinoma | Ovarian Seromucinous Carcinoma | Ovarian Serous Cystadenocarcinoma | Ovarian Undifferentiated Carcinoma

United States
National Cancer Institute (NCI)

Completed

Wilm's Tumor 1 Protein Vaccine to Treat Cancers of the Blood

Myelodysplastic Syndrome (MDS) | Non-Hodgkin's Lymphoma (NHL) | Leukemia, Acute Myelogenous (AML) | Leukemia, Acute Lymphocytic (ALL) | Leukemia, Chronic Myelogenous (CML)

United States
Roswell Park Cancer Institute
National Cancer Institute (NCI)

Active, not recruiting

Gene-Modified T Cells With or Without Decitabine in Treating Patients With Advanced Malignancies Expressing NY-ESO-1

Metastatic Melanoma | Advanced Malignant Solid Neoplasm | Unresectable Melanoma | Clinical Stage III Cutaneous Melanoma AJCC v8 | Pathologic Stage IIIB Cutaneous Melanoma AJCC v8 | Pathologic Stage IIIC Cutaneous Melanoma AJCC v8 | Pathologic Stage IIID Cutaneous Melanoma AJCC v8 | Pathologic Stage... and other conditions

United States
Pirogov Russian National Research Medical University

Completed

Endometrial Tissues and Mononuclear Cells Receptivity in Pathogenesis of Endometrial Proliferative Processes

Endometrial Cancer | Endometrial Hyperplasia Without Atypia | Postmenopause | Peripheral Blood Mononuclear Cells | Endometrial Hyperplasia With Atypia | Estrogen Receptor | Progesterone Receptor
University Hospital, Tours

Completed

Lengthening Temporalis Myoplasty and Improvement of Primary Swallowing Disorders in Facial Paralysis (MATPF)

Peripheral Facial Paralysis

France
Hospices Civils de Lyon

Not yet recruiting

Impact of Obesity, Chronic Kidney Disease and Type 2 Diabetes on Human Urinary Stem Cells (URISTEM)

Obesity | Chronic Kidney Diseases | Diabetes type2 | Stem Cells

France
Zhuan Zhang

Completed

Effect of Stellate Ganglion Block Combined With Facial Nerve Block on the Treatment of Idiopathic Facial Paralysis

Peripheral Facial Palsy

China
Poitiers University Hospital

Recruiting

Staphylococcal Toxins in Atopic Dermatitis and Eczema Herpeticum (STADEH)

Immune Response | Staphylococcus Aureus | Atopic Dermatitis | Cytokines | Bacterial Toxins | T Cells Subsets

France
Dalarna County Council, Sweden
Karolinska Institutet

Recruiting

Evaluation of Cortisone Treatment in Children With Acute Facial Nerve Palsy (FACE)

Facial Nerve Diseases | Facial Palsy | Bell Palsy | Borrelia Infection of Central Nervous System

Sweden
Daping Hospital and the Research Institute of Surgery...

Recruiting

Transfusion of Red Blood Cells for Acute Respiratory Distress Syndrome(ARDS) in Neonates

Acute Respiratory Distress Syndrome (ARDS) | Red Blood Cells(RBC)

China
Wageningen University

Active, not recruiting

Prospective Cohort Study of 4,837 Post-myocardial Infarction Patients (Alpha Omega Cohort)

Cardiovascular Diseases | Mortality | Type 2 Diabetes Mellitus | Cognitive Decline | Mental Well-being | Kidney Function

Netherlands
858 Therapeutics, Inc.

Recruiting

A Study of PARG Inhibitor ETX-19477 in Patients With Advanced Solid Malignancies (ERADIC8)

Breast Cancer | Gastric Cancer | Colorectal Cancer | Ovarian Cancer | Prostate Cancer | Endometrial Cancer | Epithelial Ovarian Cancer | BRCA1 Mutation | BRCA2 Mutation | Advanced or Metastatic Solid Tumors | ER+ Breast Cancer | Castrate Resistant Prostate Cancer | BRCA Mutation

United States
Global Healthy Living Foundation
University of Alabama at Birmingham

Recruiting

PatientSpot Formerly Known as ArthritisPower (GHLF)

Heart Failure | Stroke | Epilepsy | Multiple Sclerosis | Obesity | Diabetes | Chronic Obstructive Pulmonary Disease | Osteoarthritis | Rheumatoid Arthritis | Parkinson Disease | Peripheral Arterial Disease | Inflammatory Bowel Diseases | Amyotrophic Lateral Sclerosis | Psoriasis | Asthma | Muscular Dystrophy | Fibromyalgia | Alzheimer... and other conditions

United States
Eli Lilly and Company
Merck Sharp & Dohme LLC; Loxo Oncology, Inc.

Recruiting

Study of LY3537982 in Cancer Patients With a Specific Genetic Mutation (KRAS G12C)

Carcinoma, Non-Small-Cell Lung | Colorectal Neoplasms | Pancreatic Neoplasms | Ovarian Neoplasms | Endometrial Neoplasms | Biliary Tract Neoplasms

Canada, United States, Japan, Australia, France, Korea, Republic of
University Hospital, Brest

Recruiting

PRediction Of DIverse Glucocorticoids toxIcity OUtcomeS (PRODIGIOUS)

Giant Cell Arteritis | Polymyalgia Rheumatica | ANCA Associated Vasculitis | Inflammatory Rheumatism | Idiopathic Inflammatory Myopathies | Systemic Autoimmune Disease

France
Mandos LLC

Terminated

Adrabetadex to Treat Niemann-Pick Type C1 (NPC1) Disease

Niemann-Pick Disease, Type C

United States, Australia, United Kingdom, Turkey, Switzerland, Germany, New Zealand, Singapore, France
Bellicum Pharmaceuticals

Active, not recruiting

Study of Gene Modified Donor T-cells Following TCR Alpha Beta Positive Depleted Stem Cell Transplant

Lymphoma, Non-Hodgkin | Myelodysplastic Syndromes | Acute Lymphoblastic Leukemia | Anemia, Aplastic | Primary Immune Deficiency Disorder | Cytopenia | Osteopetrosis | Leukemia, Acute Myeloid (AML), Child | Hemoglobinopathy in Children

United States
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Completed

Yttrium-90 Anti-CD45 Monoclonal Antibody BC8 Followed by Donor Stem Cell Transplant in Treating Patients With High-Risk AML, ALL, or MDS

Chronic Myelomonocytic Leukemia | Previously Treated Myelodysplastic Syndrome | Recurrent Adult Acute Myeloid Leukemia | Secondary Acute Myeloid Leukemia | Recurrent Adult Acute Lymphoblastic Leukemia | Refractory Anemia With Excess Blasts

United States
University of Nottingham

Completed

The Assessment of the Feasibility of a Home Based Exercise Programme in the Older Patient Following Major Surgery (POETold)

Quality of Life | Delirium | Prostatic Neoplasms | Surgery | Colorectal Carcinoma | Bladder Carcinoma | Colon Carcinoma | Impaired Cognition | Abdominal Hysterectomy (& Wertheim) | Renal Carcinoma

United Kingdom
AstraZeneca

Completed

Nexium Capsules Clinical Experience Investigation

Gastric Ulcer, Duodenal Ulcer, Anastomotic Ulcer, Reflux Oesophagitis,"Non-erosive Reflux Disease, Zollinger-Ellison Syndrome

Japan
University of Pittsburgh

Recruiting

Longitudinal Study of Neurodegenerative Disorders

Lysosomal Storage Diseases | Leukodystrophy | Niemann-Pick Diseases | Batten Disease | Gaucher Disease | Krabbe Disease | Alpha-Mannosidosis | Osteopetrosis | Tay-Sachs Disease | Pelizaeus-Merzbacher Disease | Sandhoff Disease | GM1 Gangliosidoses | MPS I | MPS II | Vanishing White Matter Disease | Multiple Sulfatase Deficiency... and other conditions

United States
AIDS Malignancy Consortium
National Cancer Institute (NCI)

Recruiting

Use of a Screening Tool to Describe HIV-Related Cancer Burden and Patient Characteristics in the AMC

HIV Infections | Cancer | HPV-Related Malignancy | Anal Cancer | HIV-Associated Malignant Neoplasm | AIDS Related Lymphoma | AIDS-related Kaposi Sarcoma | AIDS-Related Malignancy

United States
Bellicum Pharmaceuticals

Terminated

Safety Study of Gene Modified Donor T Cell Infusion After Stem Cell Transplant for Non-Malignant Diseases

Hemoglobinopathies | Hemophagocytic Lymphohistiocytosis | Metabolic Disorders | Primary Immune Deficiency Disorders | Inherited Bone Marrow Failure Syndrome

United States
I-Mab Biopharma US Limited

Completed

A Clinical Study of TJ004309 With Atezolizumab (TECENTRIQ®) in Patients With Ovarian Cancer and Selected Solid Tumors

Head and Neck Cancer | Ovarian Cancer | Non Small Cell Lung Cancer | Triple Negative Breast Cancer | Gastrointestinal Cancer | Ovarian Carcinoma

United States
Mandos LLC

Completed

VTS-270 to Treat Niemann-Pick Type C1 (NPC1) Disease

Niemann-Pick Disease, Type C

United States, Australia, United Kingdom, Germany, France, New Zealand, Singapore, Spain, Turkey
National Cancer Institute (NCI)

Terminated

Phase I Trial of AZD1775 and Belinostat in Treating Patients With Relapsed or Refractory Myeloid Malignancies or Untreated Acute Myeloid Leukemia

Acute Myeloid Leukemia | Previously Treated Myelodysplastic Syndrome | Recurrent Adult Acute Myeloid Leukemia | Secondary Acute Myeloid Leukemia | Untreated Adult Acute Myeloid Leukemia | Myelodysplastic Syndrome | Refractory Acute Myeloid Leukemia | Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1... and other conditions

United States
AstraZeneca

Completed

A Phase I/III Study of D961H 10 mg and 20 mg in Japanese Paediatric Patients With Gastrointestinal Acid Related Diseases

Zollinger-Ellison Syndrome | Reflux Esophagitis (RE) | Gastric Ulcer (GU) | Duodenal Ulcer (DU) | Anastomotic Ulcer (AU) | Non-erosive Reflux Esophagitis Disease (NERD)

Japan
Azafaros A.G.

Active, not recruiting

Phase 2 Study Evaluating the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Oral AZ-3102 in Patients With GM2 Gangliosidosis or Niemann-Pick Type C Disease (RAINBOW)

Niemann-Pick Disease, Type C | GM2 Gangliosidosis

Brazil
City of Hope Medical Center
National Cancer Institute (NCI)

Active, not recruiting

Total Marrow and Lymphoid Irradiation and Chemotherapy Before Donor Transplant in Treating Patients With Myelodysplastic Syndrome or Acute Leukemia

Previously Treated Myelodysplastic Syndrome | Recurrent Adult Acute Myeloid Leukemia | Recurrent Adult Acute Lymphoblastic Leukemia | Recurrent Childhood Acute Lymphoblastic Leukemia | Recurrent Childhood Acute Myeloid Leukemia | Acute Myeloid Leukemia in Remission | Adult Acute Lymphoblastic... and other conditions

United States
VelosBio Inc.

Completed

A Study of Zilovertamab Vedotin (MK-2140) (VLS-101) in Participants With Solid Tumors (MK-2140-002)

Gastric Cancer | Pancreatic Cancer | NSCLC | Platinum-resistant Ovarian Cancer | Triple-negative Breast Cancer | ER-positive Breast Cancer | HER2-negative Breast Cancer | Non-squamous Non-small-cell Lung Cancer | Estrogen-receptor-positive Breast Cancer | Progesterone-receptor-positive Breast Cancer | Estrogen-receptor-negative... and other conditions

United States, Canada
Novartis Pharmaceuticals

Completed

A Study of Oral AMN107 in Adults With Chronic Myelogenous Leukemia (CML) or Other Hematologic Malignancies

Hypereosinophilic Syndrome | Chronic Myelogenous Leukemia | Systemic Mastocytosis | Acute Lymphoblastic Leukemia (Philadelphia Chromosome Positive)

United States, Poland, Italy, Belgium, Canada, France, Australia, Netherlands, Sweden, Switzerland, United Kingdom, Spain, Korea, Republic of, Austria, Germany, Denmark, Finland, Singapore, Taiwan, Hong Kong, New Zealand, Norway
Xinhua Hospital, Shanghai Jiao Tong University...

Unknown

Study of Lithium Carbonate to Treat Niemann-Pick Type C1 Disease

Niemann-Pick Disease, Type C1

China

Clinical Trials on Circulating Tumor Cell

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