Clinical Trials on Cirrhosis in United Kingdom

Total 491 results

Judit Pich

Completed

Simvastatin Plus Rifaximin in Decompensated Cirrhosis (LIVERHOPE)

Cirrhoses, Liver

Spain, Germany, United Kingdom, Italy, Netherlands, France
Judit Pich

Completed

Efficacy of the Combination of Simvastatin Plus Rifaximin in Patients With Decompensated Cirrhosis to Prevent ACLF Development (2018-001698-25)

Liver Cirrhoses

Belgium, Spain, United Kingdom, Italy, Netherlands, France, Germany
University of Edinburgh
NHS Lothian

Completed

Prognostic Biomarkers For Acute Kidney Injury In Liver Cirrhosis

Biomarkers | Acute Kidney Injury | Liver Cirrhoses

United Kingdom
King's College Hospital NHS Trust
King's College London; Cardiff University; Guy's and St Thomas' NHS Foundation... and other collaborators

Recruiting

Beta-blockers for Oesophageal Varices (BOPPP)

Cirrhoses, Liver | Oesophageal Varices

United Kingdom
King's College London
King's College Hospital NHS Trust

Completed

Trial of Faecal Microbiota Transplantation in Cirrhosis (PROFIT)

Cirrhosis of the Liver

United Kingdom
Royal Free Hospital NHS Foundation Trust
Innovate UK

Active, not recruiting

CirrhoCare in COVID-19: A Pilot, Remote, Home Monitoring Study in Advanced Cirrhosis

Decompensated Cirrhosis

United Kingdom
University of Nottingham
Mediplus Ltd UK; Enteric healthcare technology Co-operative

Completed

Evaluation of 'Melody' Paracentesis Device for Ascites Therapy (EMPATHY)

Ascites Hepatic | Cirrhosis and Chronic Liver Disease

United Kingdom
Nottingham University Hospitals NHS Trust
VSL Pharmaceuticals

Terminated

VSL#3 and Spontaneous Bacterial Peritonitis

Decompensated Cirrhosis | Ascites

United Kingdom
Light Chain Bioscience - Novimmune SA

Terminated

Primary Biliary Cirrhosis: Investigating A New Treatment Option Using NI-0801, an Anti-CXCL10 Monoclonal Antibody (PIANO)

Primary Biliary Cirrhosis

Italy, United Kingdom
University of Aberdeen

Completed

The Utility of Breath Biopsy as a Screening Tool for HCC (BrtH-C)

HCC | Cirrhosis, Liver

United Kingdom
Novartis Pharmaceuticals

Completed

An Exploratory Haemodynamic Study in Patients With Compensated Cirrhosis and Portal Hypertension

Compensated Cirrhosis and Portal Hypertension

United Kingdom
University of Leeds
The Leeds Teaching Hospitals NHS Trust

Unknown

Functional MRI to Determine Severity of Cirrhosis

Liver Cirrhosis | Liver Fibrosis

United Kingdom
University College, London
London School of Hygiene and Tropical Medicine; CyberLiver Ltd

Recruiting

CirrhoCare- Using Smart-phone Technology to Enhance Care and Access to Treatment for Cirrhosis (CirrhoCare)

Decompensated Cirrhosis

United Kingdom
Massachusetts General Hospital
Shriners

Recruiting

Developing Viability Index for Machine Perfused Livers

Liver Cirrhoses

United States
Guy's and St Thomas' NHS Foundation Trust
King's College Hospital NHS Trust

Unknown

Paternally Inherited Phenotypes in Cholestasis (PIP-C)

Primary Sclerosing Cholangitis | Cholestasis | Primary Biliary Cirrhosis

United Kingdom
Newcastle-upon-Tyne Hospitals NHS Trust
Newcastle University; National Institute for Health Research, United Kingdom; Department of Health, United Kingdom

Completed

B-Cell Depleting Therapy (Rituximab) as a Treatment for Fatigue in Primary Biliary Cirrhosis (RITPBC)

Fatigue | Primary Biliary Cirrhosis

United Kingdom
University of Oxford
British Heart Foundation; Oxford University Hospitals NHS Trust

Unknown

Multiparametric MR for Rapid Imaging Assessment of the Liver (RIAL)

Liver Cirrhosis | Fatty Liver

United Kingdom
University of Edinburgh
NHS Lothian

Completed

Early Use of TIPSS in Patients With Cirrhosis and Variceal Bleeding (EarlyTIPSS)

Liver Cirrhosis | Variceal Haemorrhage

United Kingdom
Fast Forward Pharmaceuticals

Unknown

Pilot Study of FFP104 Dose Escalation in PBC Subjects

Primary Biliary Cirrhosis

Netherlands, United Kingdom
Imperial College London

Recruiting

Volatile Organic Compounds for the Assessment of Liver Disease (VOCAL)

Hepatocellular Carcinoma | Cirrhosis | Fibrosis, Liver | Cirrhosis, Liver | Hepatocellular Cancer

United Kingdom
University of Edinburgh
Novartis Pharmaceuticals; NHS Lothian

Completed

Serelaxin To Lower Portal Pressure (STOPP)

Liver Cirrhosis | Hypertension, Portal

United Kingdom
GlaxoSmithKline

Completed

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics (PK) and Pharmacodynamics (PD) of Repeat Doses of GSK2330672 Administration in Subjects With Primary Biliary Cirrhosis (PBC) and Symptoms of Pruritus

Cholestasis, Intrahepatic

United Kingdom
University of Alberta
GlaxoSmithKline; Axcan Pharma

Completed

Study of Combivir for Patients With Primary Biliary Cirrhosis

Primary Biliary Cirrhosis

United States, Canada, United Kingdom
University of Nottingham
National Institute for Health Research, United Kingdom

Completed

Biomarkers for the Prognosis of Decompensated Alcoholic Liver Disease (BANDED)

Decompensated Cirrhosis | Alcoholic Liver Diseases

United Kingdom
Aleksander Krag
EASL - CLIF Consortium

Recruiting

Personalized Long-term Human Albumin Treatment in Patients With Decompensated Cirrhosis and Ascites

Decompensated Cirrhosis and Ascites

Spain, Denmark, United Kingdom, Hungary, Germany, Belgium, Netherlands
Medical College of Wisconsin

Terminated

Early Cycle Ergometry for Critically-Ill Liver Failure Patients in a Transplant Intensive Care Unit

Liver Failure | ICU Acquired Weakness | Liver Cirrhoses

United States
Perspectum

Completed

Repeatability and Reproducibility of Quantitative MRCP

Liver Diseases | Primary Sclerosing Cholangitis | Gallstones | Primary Biliary Cirrhosis

United Kingdom
Resolution Therapeutics Limited

Recruiting

Study in Patients With Decompensated Liver Cirrhosis (OPAL)

Liver Cirrhosis

United Kingdom
St George's, University of London
King's College Hospital NHS Trust

Recruiting

S100A8/A9 and Innate Immunity in Liver Disease

Infections | Cirrhosis, Liver | Ascites Hepatic | Immune Suppression | Liver Failure, Acute on Chronic

United Kingdom
Sequana Medical N.V.

Terminated

Alfapump-albumin Replacement Therapy

Liver Cirrhosis

United Kingdom
Yaqrit Ltd
Assistance Publique - Hôpitaux de Paris; IRCCS Azienda Ospedaliero-Universitaria... and other collaborators

Terminated

Safety and Tolerability of Yaq-001 in Patients With Cirrhosis

Liver Cirrhosis

France, Italy, Portugal, Spain, United Kingdom, Switzerland
University of Birmingham
University Hospital Birmingham NHS Foundation Trust; Intercept Pharmaceuticals

Terminated

EXerCise Intervention in cholesTatic LivEr Disease: The EXCITED Study (EXCITED)

Primary Biliary Cholangitis

United Kingdom
University of California, San Diego
Icahn School of Medicine at Mount Sinai; Bayer Healthcare Pharmaceuticals,...

Recruiting

Gadolinium Contrast-enhanced Abbreviated MRI (AMRI) vs. Standard Ultrasound for Hepatocellular Carcinoma (HCC) Surveillance in Patients With Cirrhosis

Liver Cancer | Liver Carcinoma | Liver Cirrhoses

United States
Manchester University NHS Foundation Trust
Roche Pharma AG; Imperial College London; University of Manchester; Unity Insights

Recruiting

Real-world Elecsys® GAAD Implementation and Validation to Improve Surveillance and Early Detection of HCC (REVISE-HCC)

Liver Cirrhosis | Hepatocellular Carcinoma

United Kingdom
King's College Hospital NHS Trust
King's College London

Completed

Randomised Controlled Trial of Mechanistic Effects of Rifaximin in Cirrhosis and Chronic Hepatic Encephalopathy (RIFSYS)

Liver Cirrhosis | Hepatoencephalopathy, Early Fatal Progressive

United Kingdom
Matthew Armstrong
Queen Elizabeth Hospital NHS Foundation Trust

Completed

Impact of Exercise Therapy on Functional Capacity in Patients Listed for Liver Transplantation

Liver Cirrhosis | Liver Dysfunction

United Kingdom
Albireo

Completed

An Open Label, Single-dose, Single Period ADME Study of A4250 in Healthy Subjects

Primary Biliary Cirrhosis | Alagille Syndrome | Progressive Familial Intrahepatic Cholestasis | Orphan Cholestatic Liver Diseases

United Kingdom
King's College Hospital NHS Trust

Not yet recruiting

Sexual Dysfunction in Patients With Chronic Liver Disease

Liver Diseases | Liver Cirrhosis

United Kingdom
University of Nottingham

Completed

Magnetic Resonance Imaging in the Evaluation of Liver Fibrosis (Mrker)

Liver Fibrosis

United Kingdom
Nottingham University Hospitals NHS Trust

Recruiting

Prospective Single Centre Observational Study to Compare the Diagnostic Yield of Different Modalities of Liver Biopsy

Liver Diseases | Liver Fibrosis

United Kingdom
Nanfang Hospital of Southern Medical University
Changhai Hospital; LanZhou University; Beijing 302 Hospital; Sheffield Teaching... and other collaborators

Unknown

Detachable String Magnetically Controlled Capsule Endoscopy for Detecting High-risk Varices in Compensated Cirrhosis

Compensated Cirrhosis | Gastroesophageal Varices Bleeding

China, United Kingdom
Sidney Kimmel Cancer Center at Thomas Jefferson...
National Cancer Institute (NCI); GE Healthcare; Bracco Diagnostics, Inc

Completed

Contrast-Enhanced Ultrasound Imaging in Diagnosing Liver Cancer in Patients With Cirrhosis

Liver Cirrhosis

United States, United Kingdom, Italy, Switzerland, Canada, France
King's College Hospital NHS Trust
King's College London; Cardiff University; Brighton and Sussex University Hospitals...

Recruiting

Beta-blockers or Placebo for Primary Prophylaxis (BOPPP) of Oesophageal Varices Trial. (BOPPP)

Portal Hypertension | Cirrhosis, Liver | Variceal Hemorrhage | Varices, Esophageal

United Kingdom
Imperial College London

Completed

Adult Stem Cell Therapy in Liver Insufficiency

Liver Cirrhosis

United Kingdom
Intercept Pharmaceuticals

Completed

Study of INT-747 as Monotherapy in Participants With Primary Biliary Cirrhosis (PBC)

Liver Cirrhosis, Biliary

United States, France, Germany, Spain, United Kingdom, Canada, Austria
Sequana Medical N.V.

Completed

ALFApump System Post Marketing Surveillance Registry (2011-AAR-004)

Liver Cirrhosis | Malignant Ascites | Refractory Ascites

Germany, Switzerland, Spain, United Kingdom
Mirum Pharmaceuticals, Inc.

Withdrawn

An Open-label Study to Evaluate the Long-term Safety and Tolerability of LUM001 in Patients With Primary Biliary Cirrhosis (CASCADE)

Primary Biliary Cirrhosis

United States, United Kingdom
Owlstone Ltd
Clinical Research and Trials Unit (Norfolk & Norwich University Hospital,... and other collaborators

Not yet recruiting

Early Liver Disease Breath Detection

Liver Diseases | Liver Fibrosis | NASH

United Kingdom
Mirum Pharmaceuticals, Inc.

Completed

Phase 2 Study to Evaluate LUM001 in Combination With Ursodeoxycholic Acid in Patients With Primary Biliary Cirrhosis (CLARITY)

Primary Biliary Cirrhosis | PBC

United States, United Kingdom, Canada
University Hospital, Basel, Switzerland
Swiss National Science Foundation

Recruiting

MERTK Signalling in Monocytes/Macrophages in Patients With Liver Disease

Liver Failure | Acute-On-Chronic Liver Failure | Liver Disease | Cirrhosis of the Liver

Switzerland, United Kingdom

Clinical Trials on Cirrhosis in United Kingdom

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