Clinical Trials on Clinical Study - RCT in South Africa

Total 99 results

University of Cape Town

Withdrawn

Impact of Medical Follow-up Discharge Package (RECALL-CT)

Follow-up Study | Medical In-patients

South Africa
University of KwaZulu
The ELMA Foundation; KwaZulu Natal Department of Health

Completed

An Evaluation of the Effectiveness of e-IMCI Implementation in Primary Health Care Clinics in South Africa.

Primary Health Care | Child Health | Clinical Practice Guidelines

South Africa
Alvotech Swiss AG

Active, not recruiting

AVT03 With Xgeva in Healthy Male Subjects

This is a Phase Study Conducted in Healthy Volunteers

South Africa
Chris Hani Baragwanath Academic Hospital
Masimo Corporation

Completed

Usefulness of Non-invasive Pulse Co-oximetry Haemaglobin Measurements in Critically Ill Black Patients

Critically Ill Black Patients

South Africa
University of Stellenbosch
Fresenius Kabi

Recruiting

Effect of Combined IV Bolus Amino Acid Supplementation and Mobilisation on Muscle Mass in Patients Over the First Week of ICU Care: RCT

Critical Illness

South Africa
University of Cape Town
National Institute of Mental Health (NIMH)

Completed

Task Sharing Counseling Intervention by Community Health Workers for Prenatal Depression in South Africa (AFFIRM-SA)

Postpartum Depression | Clinical Depression | Moderate Depression

South Africa
Advanced Imaging Projects, LLC
All India Institute of Medical Sciences, New Delhi; US Department of Veterans... and other collaborators

Not yet recruiting

Safety and Efficacy of Ga68 Αvβ3 IAC PET/CT for Diagnosis and Clinical Management in Angiogenic Breast Cancer Patients (Shiva)

Diagnosis and Clinical Management of Angiogenic Breast Cancer

South Africa, India
University of Sheffield
Ethicon Endo-Surgery; HCA International Limited; Digimed

Completed

Educational Study of Multimedia in Surgical Skills Training in Colorectal Surgery

Focus of Study: Cognitive Surgical Skill Acquisition

United Kingdom
Lykos Therapeutics

Completed

Psychological Effects of Methylenedioxymethamphetamine (MDMA) When Administered to Healthy Volunteers (MT-1)

Psychological Effects of Study Drug

United States
Ohio State University
University of Hohenheim; Universidad de Costa Rica

Completed

Comparison of Carotenoid Bioavailability From Fresh Papaya, Tomato and Carrot

Focus of Study: Carotenoid Absorption

United States, Costa Rica
Erasmus Medical Center
Dutch Heart Foundation

Completed

CholGate - The Effect of Alerting Versus on Demand Computer Based Decision Support on Treatment of Dyslipidaemia by General Practitioners

Decision Support Systems, Clinical

Netherlands
Allergan

Completed

Safety Extension Study to Evaluate the Biodegradation of the Brimonidine Tartrate Posterior Segment Drug Delivery System

Patients Who Participated in an Intravitreal Brimo PS DDS® Study

France, United Kingdom, Korea, Republic of, Czech Republic, Australia, Israel, India, Portugal, Germany, United States, Italy, Philippines
Biotronik SE & Co. KG

Completed

ProMRI PROVEN Master Study

Safety of MR (Magnetic Resonance) Conditional CRT-pacemakers and ICDs

France, Germany, Hungary, Canada, Australia, Austria, Czech Republic, Switzerland
The George Institute for Global Health, Australia

Completed

The Fluid Translation of Research Into Practice Study (Fluid-TRIPS)

Critical Care, Fluid Resuscitation

Australia
R3 Vascular Inc.

Recruiting

Evaluation of the MAGNITUDE® Bioresorbable Drug-Eluting Scaffold in the Treatment of Patients With Below the Knee Disease in Australia (MAGNITUDE-BTK)

Critical Limb Ischemia | Critical Lower Limb Ischemia | Critical Limb-Threatening Ischemia

Australia
Medical University of South Carolina
Siemens Corporation, Corporate Technology

Terminated

PET-DECT for Staging and Imaged Based Radiotherapy Planning in Lung Cancer

PET CT

United States
Australian and New Zealand Intensive Care Research...
Baxter Healthcare Corporation

Active, not recruiting

Intensive Nutrition in Critically Ill Adults (INTENT)

Critical Illness | Critically Ill

Australia, New Zealand
Prisma Health-Upstate
National Institute on Drug Abuse (NIDA); Clemson University

Recruiting

An Integrated Intervention Involving Recovery Coaching and Cognitive Behavioral Therapy for Opioid Use Disorder (OVERCOME 2)

Standard of Care | Standard of Care + CBT4CBT | Standard of Care + CBT4CBT + RC

United States
South West Sydney Local Health District

Completed

Fluid Responsiveness After CArdiac Surgery Study (FRACAS)

Critically Ill | Hypovolemia

Australia
Takeda
Theravance Biopharma

Completed

A Randomized, Double-Blind Study to Evaluate the Safety, Tolerability, and Pharmacodynamics of a Single Dose of Intravenous TD-8954 Compared With Metoclopramide in Critically Ill Patients With Enteral Feeding Intolerance

Enteral Feeding Intolerance

Australia
Vidacare Corporation

Terminated

Observational Study of CT Dye Administration Through the Intraosseous Vascular Access Route

Intraosseous Vascular Access Patients Requiring CT Exam

United States
Applied Physiology Pty Ltd
Trident Clinical Research Pty Ltd

Completed

Registration Enabling Study of the Safety and Efficacy of the Use of the Navigator Circulatory Management System (NAV-1)

Critical Illness | Intensive Care

Australia
National Cancer Institute (NCI)

Suspended

Nivolumab and Ipilimumab in Treating Patients With Esophageal and Gastroesophageal Junction Adenocarcinoma Undergoing Surgery

Esophageal Adenocarcinoma | Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8 | Gastroesophageal Junction Adenocarcinoma | Clinical Stage II Esophageal Adenocarcinoma AJCC v8 | Clinical Stage III Esophageal Adenocarcinoma AJCC v8 | Clinical Stage IVA Esophageal Adenocarcinoma... and other conditions

United States
Amgen

Completed

Registry Study for Talimogene Laherparepvec

Any Tumor Type Eligible for Treatment With Talimogene Laherparepvec in Amgen or BioVEX-sponsored Clinical Trial

Canada, Spain, United States, Germany, Austria, France, Greece, Hungary, Italy, Korea, Republic of, Poland, Russian Federation, South Africa, Switzerland, United Kingdom
Hasanuddin University

Completed

High Protein Formula on Enteral Feeding in Clinical Improvement and Malnutrition at Intensive Care Unit Patients

Critically Ill | Intensive Care Unit

Indonesia
The George Institute
National Health and Medical Research Council, Australia; University of British... and other collaborators

Completed

Normoglycaemia in Intensive Care Evaluation and Survival Using Glucose Algorithm Regulation (NICE - SUGAR STUDY)

Hyperglycemia | Critical Illness

Australia
Chung Shan Medical University

Enrolling by invitation

AI Determine Malignancy of GGO on Chest CT

Lung Nodules, Early Lung Cancer, Artificial Intelligence, Chest CT, Minimally Invasive Surgery, Lung Image Analysis Software

Taiwan
Erasmus Medical Center

Completed

Music for Anxiety in Critically Ill Patients (RELACS)

Anxiety

Netherlands
Australian and New Zealand Intensive Care Research...

Active, not recruiting

INTENT-Muscle (A Sub-study of INTENT)

Critically Ill

Australia, New Zealand
GlaxoSmithKline

Completed

Evaluation of Single Doses of GSK962040 in Critically Ill Patients With Enteral Feed Intolerance

Gastroparesis

Australia
The George Institute

Completed

Fludrocortisone Dose Response Relationship in Septic Shock - FluDReSS (FluDReSS)

Septic Shock | Critically Ill

Australia
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Recruiting

mFOLFIRINOX Versus mFOLFOX With or Without Nivolumab for the Treatment of Advanced, Unresectable, or Metastatic HER2 Negative Esophageal, Gastroesophageal Junction, and Gastric Adenocarcinoma

Clinical Stage III Gastric Cancer AJCC v8 | Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8 | Clinical Stage IV Gastric Cancer AJCC v8 | Clinical Stage IV Gastroesophageal Junction Adenocarcinoma AJCC v8 | Metastatic Gastric Adenocarcinoma | Metastatic Gastroesophageal Junction... and other conditions

United States, Puerto Rico
Amgen

Recruiting

Sotorasib Activity in Subjects With Advanced Solid Tumors With KRAS p.G12C Mutation (CodeBreak 101)

Advanced Solid Tumors | Kirsten Rat Sarcoma (KRAS) pG12C Mutation

United States, Italy, Taiwan, Spain, United Kingdom, Australia, Austria, Germany, Belgium, Japan, Netherlands, Korea, Republic of, Canada
Australian and New Zealand Intensive Care Research...

Completed

The Augmented Versus Routine Approach to Giving Energy Trial (TARGET)

Critical Illness

Australia, New Zealand
Boston Scientific Corporation

Completed

LONGEVITY Study. Evaluation of the Device and Battery Longevity of Boston Scientific Market-released ICD and CRT-D Devices

Implantable Cardioverter Defibrillators | CRT-D Cardiac Resynchronization Therapy Defibrillator

Korea, Republic of, United States, United Kingdom, Japan, Germany, Canada, Spain, Switzerland
Daren K. Heyland
Ministry of Research, Innovation and Science, Ontario; Canadian Foundation...

Completed

PERFormance Enhancement of the Canadian Nutrition Guidelines by a Tailored Implementation Strategy: The PERFECTIS Study (PERFECTIS)

Critically Ill | Intensive Care Unit

Canada, United States
Australian and New Zealand Intensive Care Research...

Recruiting

Indirect Calorimetry Guided Energy Provision in Critically Ill Patients With Obesity (DIRECT)

Obesity | Critical Illness

Australia
Abbott Medical Devices

Active, not recruiting

LIFE-BTK PK Sub-study

Critical Limb Ischemia (CLI)

Taiwan, United States, Australia
Brigham and Women's Hospital
National Institute of Mental Health (NIMH); Yale University; Orygen

Recruiting

AMP SCZ® Observational Study: PREDICT-DPACC (AMP SCZ)

Psychosis | Remission | Conversion | Clinical High Risk

United States, United Kingdom, Canada, Italy, Australia, Chile, China, Denmark, Germany, Hong Kong, Korea, Republic of, Singapore, Spain, Switzerland
ECOG-ACRIN Cancer Research Group
National Cancer Institute (NCI)

Recruiting

Testing the Addition of Radiotherapy to the Usual Treatment (Chemotherapy) for Patients With Esophageal and Gastric Cancer That Has Spread to a Limited Number of Other Places in the Body

Clinical Stage IV Gastric Cancer AJCC v8 | Metastatic Gastric Adenocarcinoma | Clinical Stage IV Esophageal Adenocarcinoma AJCC v8 | Clinical Stage IVA Esophageal Adenocarcinoma AJCC v8 | Clinical Stage IVA Gastric Cancer AJCC v8 | Clinical Stage IVB Esophageal Adenocarcinoma AJCC v8 | Clinical... and other conditions

United States
NRG Oncology
National Cancer Institute (NCI)

Recruiting

Testing the Addition of the Anti-cancer Viral Therapy Telomelysin™ to Chemoradiation for Patients With Advanced Esophageal Cancer and Are Not Candidates for Surgery

Clinical Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8 | Unresectable Gastroesophageal Junction Adenocarcinoma | Postneoadjuvant Therapy Stage III Gastroesophageal Junction Adenocarcinoma AJCC v8 | Postneoadjuvant Therapy Stage IIIA Gastroesophageal Junction Adenocarcinoma... and other conditions

United States
Australian and New Zealand Intensive Care Research...

Recruiting

Bone Loss Prevention With Zoledronic Acid or Denosumab in Critically Ill Adults (BoneZone)

Critical Illness | Osteoporosis

Australia, New Zealand
Chantal Kats

Recruiting

External Validation of the Beta-lactam Target Non-attainment (BATMAN) Risk Score in Adult ICU Patients: a Diagnostic Multivariate Predictive Risk Model (BATMAN)

Infection, Bacterial | Beta-lactam Antibiotics | Critical Care | Risk Model | Therapeutic Drug Monitoring

Netherlands
Australian and New Zealand Intensive Care Research...
Monash University; The Alfred; St Vincent's Hospital, Sydney; Royal Prince Alfred... and other collaborators

Completed

Extracorporeal Membrane Oxygenation Physical Training (ECMO-PT)

Extracorporeal Membrane Oxygenation Complication | Critically Ill, Mechanically Ventilated

Canada, Australia
Australian and New Zealand Intensive Care Research...
National Health and Medical Research Council, Australia

Completed

Early Goal-Directed Sedation Compared With Standard Care in Mechanically Ventilated Critically Ill Patients (SPICE III RCT)

Critical Illness and Mechanical Ventilation

Australia, United Kingdom, Italy, New Zealand, Malaysia, Ireland, Switzerland, Saudi Arabia
BeiGene

Recruiting

Study of BGB-A425 and LBL-007 in Combination With Tislelizumab in Advanced Solid Tumors

Locally Advanced or Metastatic Solid Tumors for Phase 1,Dose Escalation and Phase 2 Safety Lead-in, HNSCC, NSCLC and RCC Participants for Phase 2

Australia, United States, Spain, France, Italy, Korea, Republic of, Poland
Millennium Pharmaceuticals, Inc.

Terminated

TAK-954 in Critically Ill Participants With Enteral Feeding Intolerance (EFI)

Critical Illness | Enteral Nutrition | Enteral Feeding Intolerance

United States, Canada, Australia, United Kingdom
Leiden University Medical Center
HollandPTC; Varian Medical Systems

Recruiting

Image Assisted Optimization of Proton Radiation Therapy in Chordomas and Chondrosarcomas (CHIPT)

Magnetic Resonance Imaging | Chondrosarcoma | Chordoma | Proton Therapy | Bone Neoplasm of Vertebral Column | PET-CT

Netherlands
Abbott Medical Devices

Active, not recruiting

LIFE-BTK Randomized Controlled Trial (LIFE-BTK)

Critical Limb Ischemia (CLI)

United States, Hong Kong, Australia, New Zealand, Singapore, Taiwan
Australian and New Zealand Intensive Care Research...
National Health and Medical Research Council, Australia; Intensive Care National... and other collaborators

Completed

Treatment of Invasively Ventilated Adults With Early Activity and Mobilisation (TEAM(III))

Critically Ill, Mechanically Ventilated

Australia, New Zealand, United Kingdom, Ireland, Germany

Clinical Trials on Clinical Study - RCT in South Africa

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Brazil

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Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

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