Clinical Trials on Clinical High-Risk
Total 6425 results
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Genelux CorporationGOG FoundationRecruitingFallopian Tube Cancer | Platinum-resistant Ovarian Cancer | Platinum-refractory Ovarian Cancer | Primary Peritoneal Cancer | High-grade Serous Ovarian Cancer | Endometrioid Ovarian Cancer | Ovarian Clear Cell CarcinomaUnited States
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Swiss GO Trial GroupHoffmann-La Roche; Novartis Pharmaceuticals; AGO Study Group; Anticancer Fund,... and other collaboratorsRecruitingFallopian Tube Neoplasms | Peritoneal Neoplasms | Ovarian Neoplasm Epithelial | High-grade Serous Ovarian Carcinoma (HGSOC) | Low-grade Serous Ovarian Carcinoma (LGSOC) | Ovarian Endometrioid CarcinomaAustria, Switzerland, Germany
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Mayo ClinicNational Cancer Institute (NCI)RecruitingRecurrent Hodgkin Lymphoma | Chronic Myelomonocytic Leukemia | Refractory Lymphoma | Recurrent Diffuse Large B-Cell Lymphoma | Refractory Diffuse Large B-Cell Lymphoma | Recurrent Lymphoma | Clonal Cytopenia of Undetermined Significance | High Grade B-Cell Lymphoma With MYC and BCL2 or BCL6 RearrangementsUnited States
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TCR2 TherapeuticsBristol-Myers SquibbActive, not recruitingOvarian Cancer | Non Small Cell Lung Cancer | Mesothelioma | Mesothelioma, Malignant | Cholangiocarcinoma | Non Small Cell Lung Cancer Metastatic | Mesotheliomas Pleural | Mesothelioma Peritoneum | Mesothelioma; Pleura | Cholangiocarcinoma Recurrent | High Grade Ovarian Serous AdenocarcinomaUnited States, Canada
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THERAPIM PTY LTDNovotech (Australia) Pty LimitedTerminatedOvarian Cancer | Fallopian Tube Cancer | Primary Peritoneal Carcinoma | High Grade Serious or Endometrioid Carcinoma of the Ovary, Fallopian Tube, or Primary Peritoneal CancerAustralia
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University College Hospital GalwayRecruitingDiabetic Foot | Amputation | Wound Infection | Wound Complication | Wound Healing Delayed | Critical Limb-Threatening Ischaemia | Gangrene; LimbIreland
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Queen Mary University of LondonCompletedQuality of Life | Critical Illness | Chronic Kidney Diseases | Acute Kidney Injury | Muscle Loss | Major TraumaUnited Kingdom
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National Cancer Institute (NCI)RecruitingAnatomic Stage III Breast Cancer AJCC v8 | Anatomic Stage IV Breast Cancer AJCC v8 | Advanced Pancreatic Carcinoma | Metastatic Pancreatic Carcinoma | Stage II Pancreatic Cancer AJCC v8 | Stage III Pancreatic Cancer AJCC v8 | Stage IV Pancreatic Cancer AJCC v8 | Castration-Resistant Prostate Carcinoma and other conditionsUnited States
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M.D. Anderson Cancer CenterNational Cancer Institute (NCI)Active, not recruitingMetastatic Lung Non-Small Cell Carcinoma | Metastatic Melanoma | Stage IV Lung Cancer AJCC v8 | Metastatic Uveal Melanoma | Acral Lentiginous Melanoma | Clinical Stage IV Cutaneous Melanoma AJCC v8 | Leptomeningeal Neoplasm | Metastatic Mucosal Melanoma | Central Nervous System Melanoma | MelanocytomaUnited States
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Instituto de Investigación Sanitaria de la Fundación...Clinica Universidad de Navarra, Universidad de Navarra; Hospital Universitario... and other collaboratorsActive, not recruitingDiabetic Foot | Limb IschemiaSpain
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Hospital Universitari Vall d'Hebron Research InstituteCompletedCOVID-19 | Critical Illness | Venous Thromboembolism | SARS-CoV Infection | Pulmonary Embolism | Sars-CoV2 | Venous Thromboses | Pulmonary Embolism and Thrombosis | Venous Thromboses, Deep | Venous Thrombosis PulmonarySpain
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National Cancer Institute (NCI)RecruitingSmall Cell Carcinoma of the Bladder | High Grade Neuroendocrine Tumors of the Urinary TractUnited States
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Wake Forest University Health SciencesNational Heart, Lung, and Blood Institute (NHLBI)RecruitingKidney Diseases | Hypertension | Pediatric Obesity | Proteinuria | Albuminuria | Kidney Injury | Blood Pressure Disorders | Autonomic Dysfunction | Pediatric Kidney Disease | Left Ventricular Dysfunction | Left Ventricular Hypertrophy | Kidney Dysfunction | Autonomic Imbalance | Left Ventricular Diastolic Dysfunction and other conditionsUnited States
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City of Hope Medical CenterCompletedEsophageal Cancer | Esophageal Neoplasms | Gastroesophageal Reflux | Barrett Esophagus | Esophageal Adenocarcinoma | Reflux Disease | Barretts Esophagus With High Grade Dysplasia | Barrett Adenocarcinoma | Esophagus Cancer | Barrett's Esophagus Without Dysplasia | Barretts Esophagus With Dysplasia | Esophagus... and other conditionsUnited States
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Bristol-Myers SquibbNektar TherapeuticsTerminatedEwing Sarcoma | Ependymoma | Medulloblastoma | Neuroblastoma | Rhabdomyosarcoma | High-grade Glioma | Leukemia and Lymphoma | Miscellaneous Brain Tumors | Miscellaneous Solid Tumors | Relapsed, Refractory Malignant NeoplasmsUnited States, Australia, France, Germany, Italy, Spain
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British Columbia Cancer AgencyBC Cancer FoundationCompletedGastrointestinal Stromal Tumors | Colorectal Cancer Metastatic | Advanced Melanoma | Advanced Non-Small Cell Lung Carcinoma | Patients With Diagnosed Malignancies Being Considered for Clinical TrialsCanada
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IDP Discovery Pharma S.L.RecruitingChronic Lymphocytic Leukemia (CLL) | Diffuse Large B-Cell Lymphoma, Not Otherwise Specified | Multiple Myeloma (MM) | High Grade B-Cell Lymphoma, Not Otherwise Specified | Double Hit Lymphoma | Triple Hit LymphomaSpain
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Ralph NULL SalloumChildren's Hospital Medical Center, CincinnatiRecruitingHigh Grade Glioma | Medulloblastoma | Meningioma | Anaplastic Ependymoma | Recurrent Malignant Glioma | Recurrent Medulloblastoma | Refractory Malignant Glioma | Refractory Medulloblastoma | Recurrent Diffuse Intrinsic Pontine Glioma | Recurrent Primary Central Nervous System Neoplasm | Refractory Primary... and other conditionsUnited States
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MEDSI Clinical Hospital 1, ICURecruitingRespiratory Tract Infections | Pneumonia | Sepsis | Critical Illness | Respiratory Distress Syndrome | Pneumonia, Ventilator-Associated | Bloodstream InfectionRussian Federation
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Mahidol UniversityCompletedParalysis | Critical Illness | Respiratory Failure | Respiratory Distress Syndrome, Adult | Neuromuscular Blockade | ARDS, HumanThailand
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National Cancer Institute (NCI)NRG OncologyRecruitingOvarian Endometrioid Adenocarcinoma | Endometrial Carcinoma | Endometrial Clear Cell Adenocarcinoma | Endometrial Endometrioid Adenocarcinoma | Ovarian Clear Cell Adenocarcinoma | Ovarian High Grade Serous Adenocarcinoma | Platinum-Resistant Ovarian Carcinoma | Endometrial Low Grade Endometrioid... and other conditionsUnited States
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Hugo W. Moser Research Institute at Kennedy Krieger...RecruitingNeurodegenerative Diseases | Ataxia | Cerebellar Ataxia | Leukodystrophy | Adrenomyeloneuropathy | LBSL | Leukoencephalopathy With Brainstem and Spinal Cord Involvement and Lactate Elevation | Leukoencephalopathy With Brain Stem and Spinal Cord Involvement and High Lactate Syndrome (Disorder)United States
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Affiliated Hospital to Academy of Military Medical...Cancer Institute and Hospital, Chinese Academy of Medical Sciences; Peking...RecruitingAge Range ≥16 Years, Gender Unlimited | Histopathology Confirmed Diffuse Large B-cell Lymphoma or High-grade B-cell Lymphoma | Received Prior First-line Chemotherapy for DLBCL or HGBL, Failed to Reach CR for Four Cycles, or Relapsed | At Least One Positive Lesion According to the 2014... and other conditionsChina
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Cancer Research UKActive, not recruitinga. Colorectal Cancer | b. High Grade Serous Ovarian Cancer | c. Non Small-cell Lung Cancer (Squamous Cell Variant) | d. Squamous Carcinoma of the Oesophagus | e. Squamous Carcinoma of the Head and Neck (HPV Negative) | f. Urothelial Cancer | g. Breast Cancer (Triple Negative Type) | h. Pancreatic...United Kingdom
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University of Sao Paulo General HospitalCompletedSARS-CoV 2 | Critical Illness | Corona Virus Infection | Respiratory Distress Syndrome, AdultBrazil
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Northwestern UniversityNational Cancer Institute (NCI)RecruitingAdvanced Malignant Solid Neoplasm | Advanced Pancreatic Carcinoma | Metastatic Pancreatic Carcinoma | Refractory Pancreatic Carcinoma | Stage II Pancreatic Cancer AJCC v8 | Stage III Pancreatic Cancer AJCC v8 | Stage IV Pancreatic Cancer AJCC v8 | Stage III Lung Cancer AJCC v8 | Stage IV Lung Cancer... and other conditionsUnited States
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Croatian Society for Organ SupportClinical Hospital Centre ZagrebRecruitingSepsis | Systemic Inflammatory Response Syndrome | Disease | Critical Illness | Acute Respiratory Distress Syndrome | Multi Organ Failure | Infections - Pathogen UnspecifiedCroatia
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University of UlmRecruitingSepsis | Critically Ill | Pseudomonas Infections | Sepsis, Severe | Pseudomonas Septicemia | Pseudomonas; Pneumonia | Pseudomonal Bacteraemia | Pseudomonas Urinary Tract Infection | Pseudomonas Gastrointestinal Tract InfectionGermany
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Karolinska University HospitalCompletedPneumonia | Sepsis | Critical Illness | Cognitive Impairment | Acute Respiratory Distress Syndrome | Extracorporeal Circulation; Complications | Long Term Adverse EffectsSweden
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Nova Scotia Health AuthorityUniversity Health Network, TorontoTerminatedOsteoarthritis | Rheumatoid Arthritis | Avascular Necrosis | Ankylosing Spondylitis | Post-traumatic; Arthrosis | Congenital Dysplasia of the Hip | Injury of Hip and Thigh
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National Cancer Institute (NCI)CompletedRecurrent Childhood Rhabdomyosarcoma | Recurrent Adult Soft Tissue Sarcoma | Stage III Adult Soft Tissue Sarcoma | Stage IV Adult Soft Tissue Sarcoma | Dermatofibrosarcoma Protuberans | Previously Treated Childhood Rhabdomyosarcoma | Recurrent Childhood Soft Tissue Sarcoma | Adult Rhabdomyosarcoma | Adult Angiosarcoma and other conditionsUnited States
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University of UtahNational Cancer Institute (NCI)SuspendedOral Cavity Carcinoma | Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 | Stage III Hypopharyngeal Carcinoma AJCC v8 | Stage III Laryngeal Cancer AJCC v8 | Stage III Oropharyngeal... and other conditionsUnited States
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Incyte Biosciences International SàrlCompletedCervical Cancer | Hepatocellular Carcinoma | Esophageal Cancer | Ovarian Cancer | Mesothelioma | Non-small Cell Lung Cancer (NSCLC) | Urothelial Carcinoma | Merkel Cell Carcinoma | Diffuse Large B-cell Lymphoma | Triple-negative Breast Cancer | Renal Cell Carcinoma (RCC) | Small Cell Lung Cancer (SCLC) | Squamous... and other conditionsUnited States
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St. Jude Children's Research HospitalRecruitingHodgkin Lymphoma | Osteosarcoma | Ewing Sarcoma | Ependymoma | Medulloblastoma | Non Hodgkin Lymphoma | Neuroblastoma | Craniopharyngioma | Rhabdomyosarcoma | Other | Brain Stem Glioma | Brain Tumors and/or Solid Tumors Including | High Grade CNS Tumors | Low Grade CNS TumorsUnited States
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M.D. Anderson Cancer CenterNational Cancer Institute (NCI)WithdrawnRecurrent B-Cell Non-Hodgkin Lymphoma | Recurrent Diffuse Large B-Cell Lymphoma | Recurrent T-Cell Non-Hodgkin Lymphoma | Recurrent High Grade B-Cell Lymphoma | Recurrent Aggressive Non-Hodgkin Lymphoma | Recurrent Burkitt Lymphoma | Recurrent Transformed B-Cell Non-Hodgkin LymphomaUnited States
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Pediatric Brain Tumor ConsortiumNational Cancer Institute (NCI); Memorial Sloan Kettering Cancer Center; American...Active, not recruitingGlioblastoma Multiforme | Medulloblastoma | Low-Grade Astrocytoma, Nos | Anaplastic Astrocytoma | Anaplastic Oligodendroglioma | Pilocytic Astrocytoma | Pineoblastoma | Supratentorial Primitive Neuroectodermal Tumor | Atypical Teratoid/Rhabdoid Tumor | Choroid Plexus Carcinoma | High-grade Astrocytoma NOS | CNS... and other conditionsUnited States
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University of OxfordIntensive Care National Audit & Research CentreActive, not recruitingMyocardial Infarction | Heart Failure | Stroke | Critical Illness | Covid19 | Renal Failure | Deep Vein Thrombosis | Pulmonary EmbolismUnited Kingdom
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University of California, San DiegoActive, not recruitingCritical Illness | Respiratory Failure | Renal Failure | Acute Respiratory Distress Syndrome | Pulmonary Disease | Extracorporeal Membrane Oxygenation Complication | Cardiac FailureUnited States
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Fondazione IRCCS Ca' Granda, Ospedale Maggiore...UnknownDiabetic Foot | Scleroderma, Systemic | Ischemic Leg | Critical Limb Ischemia | Ischemic Ulcer | Ischemic Feet | Peripheral Arterial Disease - PAD | Thrombo Angiitis ObliteransItaly
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University of Texas at AustinUnknownSepsis | Shock | Critical Illness | Shock, Septic | Respiratory Failure | Chronic Disease | Respiratory Distress Syndrome, Adult | Shock, HypovolemicUnited States
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SynthekineRecruitingRenal Cell Carcinoma | Cervical Cancer | Gastric Cancer | Non Small Cell Lung Cancer | Advanced Solid Tumor | Head and Neck Squamous Cell Carcinoma | Urothelial Carcinoma | Microsatellite Instability High | Malignant Melanoma | GastroEsophageal Cancer | Mismatch Repair DeficiencyUnited States
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M.D. Anderson Cancer CenterNational Cancer Institute (NCI)Active, not recruitingRecurrent Fallopian Tube Carcinoma | Recurrent Ovarian Carcinoma | Recurrent Primary Peritoneal Carcinoma | Recurrent Uterine Corpus Carcinoma | Endometrial Adenocarcinoma | Recurrent Breast Carcinoma | Estrogen Receptor Negative | HER2/Neu Negative | Progesterone Receptor Negative | Triple-Negative Breast... and other conditionsUnited States
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Oslo University HospitalDiakonhjemmet HospitalRecruitingDiabetes Mellitus | Diabetic Foot | Diabetic Neuropathies | Amputation | Critical Limb Ischemia | Osteomyelitis | Claudication, Intermittent | Lower Extremity Ulcer | Diabetic AngiopathyNorway
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M.D. Anderson Cancer CenterNational Cancer Institute (NCI)Active, not recruitingCervical Intraepithelial Neoplasia | Cervical Adenocarcinoma | Cervical Squamous Cell Carcinoma, Not Otherwise Specified | Vaginal Adenocarcinoma | Vulvar Intraepithelial Neoplasia | Stage I Cervical Cancer AJCC v8 | Stage IA Cervical Cancer AJCC v8 | Stage IA1 Cervical Cancer AJCC v8 | Stage IA2 Cervical... and other conditionsUnited States
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PhaseBio Pharmaceuticals Inc.TerminatedPneumonia | Respiratory Failure | Respiratory Insufficiency | COVID 19 | Acute Respiratory Distress Syndrome | SARS-CoV-2 | Coronavirus | Cytokine Storm | Pulmonary Edema | Cardiac Event | Respiratory Complication | Cardiac Dysfunction | Hypoxemic Respiratory Failure | Hypoxic Respiratory Failure | Cardiac Failure | Cardiac... and other conditionsUnited States
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National Cancer Institute (NCI)CompletedUnspecified Childhood Solid Tumor, Protocol Specific | Recurrent Childhood Medulloblastoma | Recurrent Childhood Ependymoma | Recurrent Childhood Grade III Lymphomatoid Granulomatosis | Recurrent Childhood Large Cell Lymphoma | Recurrent Childhood Lymphoblastic Lymphoma | Recurrent Childhood Small... and other conditionsUnited States
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M.D. Anderson Cancer CenterNational Cancer Institute (NCI)Active, not recruitingMetastatic Renal Cell Carcinoma | Metastatic Lung Non-Small Cell Carcinoma | Stage IVA Lung Cancer AJCC v8 | Stage IVB Lung Cancer AJCC v8 | Metastatic Melanoma | Fallopian Tube Carcinoma | Advanced Malignant Solid Neoplasm | Stage III Lung Cancer AJCC v8 | Stage IV Lung Cancer AJCC v8 | Stage III Renal... and other conditionsUnited States
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University of WashingtonMinnesota Ovarian Cancer AllianceTerminatedStage III Ovarian Cancer AJCC v8 | Stage IIIA Ovarian Cancer AJCC v8 | Stage IIIA1 Ovarian Cancer AJCC v8 | Stage IIIA2 Ovarian Cancer AJCC v8 | Stage IIIB Ovarian Cancer AJCC v8 | Stage IIIC Ovarian Cancer AJCC v8 | Stage IV Ovarian Cancer AJCC v8 | Stage IVA Ovarian Cancer AJCC v8 | Stage IVB Ovarian... and other conditionsUnited States
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Inovio PharmaceuticalsCompletedAnal NeoplasmUnited States, Canada
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Mayo ClinicRecruitingHematologic Neoplasms | Myeloid Malignancy | Cytopenia | Bone Marrow Failure Syndrome | Clonal Cytopenia of Undetermined Significance | Clonal Hematopoiesis of Indeterminate Potential | Low Risk Myelodysplastic Syndrome | Inherited Bone Marrow Failure Syndrome | Clonal Expansion | Hereditary Neoplastic... and other conditionsUnited States