Clinical Trials on Clostridium Enterocolitis

Total 740 results

Wake Forest University

Completed

Early Provision of Enteral Microlipid and Fish Oil to Infants With Enterostomy (EMLFO)

Necrotizing Enterocolitis | Short Bowel Syndrome | Small Intestine Perforation

United States
Fondazione IRCCS Ca' Granda, Ospedale Maggiore...
Massachusetts General Hospital

Unknown

Development and Use of a Tissue and Human Enteroid Biorepository to Study the Pathophysiology of NEC

Enterocolitis, Necrotizing | Prematurity | Gastrointestinal Disease
Assistance Publique - Hôpitaux de Paris

Recruiting

Safety Registry of a Fecal Microbiota Transplant Cohort (COSMIC-FMT)

Clostridium Difficile Infections

France
University of North Carolina, Chapel Hill
North Carolina Translational and Clinical Sciences Institute; North Carolina...

Completed

Fecal Microbiota Transplantation (FMT) in Clostridium Difficile Infection (CDI) Not Responding to Antibiotics (FMT)

Clostridium Difficile

United States
Pfizer

Completed

A Study To Investigate Two 3-dose Schedules Of A Clostridium Difficile Vaccine In Healthy Adults Aged 65 to 85 Years

Clostridium Difficile Associated Disease

United States
Pfizer

Completed

Evaluation of a 3-dose Vaccination Regimen With One of Three Ascending Dose Levels of Clostridium Difficile Vaccine With or Without Adjuvant in Healthy Adults Aged 50 to 85 Years

Clostridium Difficile Associated Disease

United States
Coordinación de Investigación en Salud, Mexico

Completed

Severe Necrotizing Enterocolitis in Preterm Newborns <1500g Using Probiotics (EPP)

Infectious Diseases

Mexico
Ain Shams University

Completed

Gut Priming With Oral Bovine Colostrum for Preterm Neonates; Randomized Control Trial

Feeding; Difficult, Newborn | Necrotizing Enterocolitis of Newborn | Late Onset Neonatal Sepsis

Egypt
Pfizer

Completed

Evaluation Of Clostridium Difficile Vaccine Lot Consistency In Healthy Adults 65 To 85 Years Of Age

Clostridium Difficile Associated Disease

United States
Pfizer

Completed

Clostridium Difficile Vaccine Safety, Tolerability, and Immunogenicity Study in Japanese Adults

Clostridium Difficile Associated Disease

Japan
Deinove

Recruiting

An Exploratory, Open-Label, Oligo-Center Study to Evaluate the Safety, Efficacy, and Pharmacokinetics of Intravenous DNV3837 in Subjects With Clostridium Difficile Infection

Clostridium Difficile (C. Difficile)

United States, Canada
Pfizer

Completed

Clostridium Difficile Vaccine 2-Dose Versus 3-Dose Study

Clostridium Difficile Associated Disease

United States
MJM Bonten
Universiteit Antwerpen; Universitätsklinikum Köln; Da Volterra

Completed

AssessmeNT of the Incidence of Clostridium Difficile Infections in Hospitalized Patients on Antibiotic TrEatment (ANTICIPATE)

Clostridium Difficile

Germany, Spain, France, Greece, Netherlands, Romania
Astellas Pharma Europe Ltd.
Cubist Pharmaceuticals LLC

Terminated

A Post-marketing, Blinded Study to Investigate How Effective Fidaxomicin is Compared to Vancomycin in the Sustained Cure of Clostridium Difficile Infection in Adults That Are Receiving Therapy to Suppress the Immune System (FREEDOM)

Clostridium Difficile

Spain, France, Germany, Greece, Denmark, Austria, Poland
Chinese University of Hong Kong

Unknown

Clostridium Difficile Virulence Mechanism Study (CDVM Study) (CDVM)

Clostridium Difficile Infection | Clostridium Difficile

Hong Kong
Medical University of Silesia

Unknown

Prevention of Clostridium Difficile Infections Using Lactobacillus Plantarum 299v Strain

Clostridium Difficile
Hvidovre University Hospital

Unknown

Rectal Bacteriotherapy, Fecal Microbiota Transplantation or Oral Vancomycin Treatment of Recurrent Clostridium Difficile Infections

Clostridium Difficile

Denmark
Pfizer

Completed

A Study To Investigate A Clostridium Difficile Vaccine In Healthy Adults Aged 50 to 85 Years, Who Will Each Receive 3 Doses Of Vaccine.

Clostridium Difficile Associated Disease

United States
Rigshospitalet, Denmark
Odense University Hospital; Technical University of Denmark

Not yet recruiting

The Intestinal Innate Immune System in Newborns. Development and Inflammation in Health and Disease (INTINE)

Preterm Infants | Atresia; Bowel | Term Infants | Innate Inflammatory Response | Necrotising Enterocolitis

Denmark
Per Torp Sangild

Completed

Feeding Bovine Colostrum to Preterm Infants (PreColos)

Sepsis | Necrotizing Enterocolitis | Meningitis | Feeding Intolerance | Extrauterine Growth Retardation

China, Denmark
Hospital Universitario Evangelico de Curitiba

Not yet recruiting

Treatment of CDI and Recurrence With Fecal Microbiota Transplant Using Promicrobioma

Clostridium Difficile Infections
University of Pennsylvania

Terminated

Penn Microbiome Therapy (PMT) for Severe-Clostridium Difficile Infection (CDI)

Severe Clostridium Difficile Infection | Severe-Complicated/Fulminant Clostridium Difficile Infection

United States
Mikrobiomik Healthcare Company S.L.

Completed

Primary or Recurrent Clostridioides Difficile Infection Treatment With Capsules of Lyophilised Faecal Microbiota vs Fidaxomicin

Recurrent Clostridium Difficile Infection | Primary Clostridium Difficile Infection

Spain
University of Oxford
National Institute for Health Research, United Kingdom

Completed

Speed of Increasing Milk Feeds Trial (SIFT)

Premature Birth | Necrotizing Enterocolitis | Late-onset Invasive Infection

United Kingdom, Ireland
Vanderbilt University
National Institute of Environmental Health Sciences (NIEHS)

Completed

Brain Manganese Deposition in High Risk Neonates

Necrotizing Enterocolitis | Cholestasis | Digestive System Abnormalities

United States
University Hospital Tuebingen

Unknown

Fecal Microbiota Transplantation in Recurrent or Refractory Clostridium Difficile Colitis (TOCSIN)

Clostridium Difficile Infection | Clostridium Difficile

Germany
King Chulalongkorn Memorial Hospital

Completed

Effect of Oral Probiotic Supplementation on The Rate of Hospital Acquired Infection and Necrotizing Enterocolitis in Preterm Very Low Birth Weight Infants

Necrotizing Enterocolitis | Nosocomial Infection

Thailand
Clinical Research Centre, Malaysia

Unknown

A Panel of Biomarkers in Diagnosing Late-onset Neonatal Sepsis and Necrotizing Enterocolitis in Sibu Hospital (PISALONS)

Necrotizing Enterocolitis | Neonatal SEPSIS

Malaysia
National Center for Research Resources (NCRR)
Baylor College of Medicine

Completed

Study of the Relationship Between Feeding and Late Onset Sepsis and/or Necrotizing Enterocolitis in Low Birth Weight Infants

Sepsis | Necrotizing Enterocolitis

United States
Beth Israel Medical Center

Terminated

The Role of Synbiotics in Reducing Post-Operative Infections in Patients Undergoing Cardiac Surgery: A Pilot Study

Pneumonia | Cystitis | Bacteremia | Surgical Wound Infection | Enterocolitis, Pseudomembranous

United States
Vanderbilt University Medical Center
National Institutes of Health (NIH)

Terminated

PROCLAIM -- Misoprostol in the Prevention of Recurrent CDI Prevent Recurrence of Clostridium Difficile Infection With Misoprostol (PROCLAIM)

Clostridium Difficile

United States
Yara El Helou
Pharma M

Terminated

Probiotics in the Prevention of Antibiotic Induced Diarrhea and Clostridium Difficile Associated Diarrhea.

Diarrhea, Clostridium Difficile

Lebanon
Vanderbilt University
The Gerber Foundation

Completed

Neurodevelopment and Neuroimaging in Parenterally-fed Infants and Young Children

Necrotizing Enterocolitis | Cholestasis | Digestive System Abnormalities | Parenteral Nutrition

United States
Assistance Publique - Hôpitaux de Paris

Recruiting

Study of the Influence of Intraperitoneal Insufflation of CO2 by Laparoscopy on the Short-term Evolution of Premature Infants With Ulcerative Necrotizing Enterocolitis (NECO2)

Preterm Birth | Enterocolitis, Necrotizing

France
Hospices Civils de Lyon

Unknown

Necrotizing Enterocolitis in Fetuses With Intrauterine Growth Restriction (ECUN)

Necrotizing Enterocolitis

France
University of Sussex
Danone Institute International

Completed

Probiotics in Preventing Antibiotic Associated Diarrhoea Including Clostridium Difficile Infection (NU278)

Diarrhoea | Clostridium Difficile

United Kingdom
University of Minnesota

Recruiting

Dietary Optimization of Microbiome Recovery Following Fecal Microbiota Transplantation

Recurrent Clostridium Difficile Infection | Fecal Microbiota Transplant

United States
Alison Schneider

Terminated

Efficacy of Metronidazole Prophylaxis Against Clostridium Difficile-Associated Diarrhea in High Risk Adult Patients

Clostridium Difficile Diarrhea

United States
University Health Network, Toronto

Terminated

Oral Vancomycin Followed by Fecal Transplant Versus Tapering Oral Vancomycin

Recurrent Clostridium Difficile Infection | Laboratory Confirmed Clostridium Difficile Infection

Canada
Sanofi

Terminated

Phase I Randomized, Placebo-Controlled, Double-Blind, Dose Ranging Study, Safety, Tolerability and Immunogenicity

Clostridium Difficile Infection | Clostridium Difficile Diarrhea
Optimer Pharmaceuticals LLC

Completed

Safety, Tolerability, and Pharmacokinetics of Fidaxomicin in Pediatric Subjects With Clostridium Difficile-associated Diarrhea (CDAD)

Clostridium Difficile-associated Diarrhea
Hadassah Medical Organization

Withdrawn

Safety and Validation of Efficacy of Oral Administration of the Food Additive Colostrum Derived Anti Clostridium Difficile Antibodies

Clostridium Difficile-Associated Diarrhea

Israel
Vedanta Biosciences, Inc.

Recruiting

VE303 for Prevention of Recurrent Clostridioides Difficile Infection (RESTORATiVE303)

Clostridium Difficile Infection Recurrence | Recurrent Clostridium Difficile Infection | Clostridium Difficile | Diarrhea Infectious | CDI | Clostridium Difficile Infections | Clostridioides Difficile Infection | C.Difficile Diarrhea | Clostridioides Difficile Infection Recurrence | C. Diff Infection

United States
Neuroganics LLC
Ramos Law Injury Firm

Recruiting

Infant Formula Feeding and Necrotizing Enterocolitis in Newborns

Necrotizing Enterocolitis | Necrotizing Enterocolitis of Newborn | Sepsis Newborn | Cows Milk Allergy

United States
University Hospital, Clermont-Ferrand
MEDIS Laboratory; QUAPA; ENTeRisk

Recruiting

Cohort of Premature Newborns for Charaterization of the Digestive Microbiota in Ulcerative Necrotizing Enterocolitis in Premature Infants (CortECS)

Premature Birth | Necrotizing Enterocolitis

France
NICHD Neonatal Research Network
Eunice Kennedy Shriver National Institute of Child Health and Human Development... and other collaborators

Completed

Laparotomy vs. Drainage for Infants With Necrotizing Enterocolitis (NEST)

Enterocolitis, Necrotizing | Intestinal Perforation | Infant, Small for Gestational Age | Infant, Premature | Infant, Low Birth Weight | Infant, Newborn

United States
Aga Khan University
United States Agency for International Development (USAID); University of Sydney

Unknown

Bovine Lactoferrin and Neonatal Survival in Low Birth Weight Babies.

Necrotizing Enterocolitis | Neonatal Sepsis

Pakistan
Burnasyan Federal Medical Biophysical Center

Unknown

Effectiveness and Safety of MMSCs for Enhancing Hematopoietic Recovery and Prophylaxis of Neutropenic Enterocolitis

Neutropenic Enterocolitis | Myeloablative Chemotherapy Induced Bone Marrow Aplasia

Russian Federation
Optimer Pharmaceuticals LLC

Completed

Safety and Efficacy of Fidaxomicin Versus Placebo for Prophylaxis Against Clostridium Difficile-Associated Diarrhea in Adults Undergoing Hematopoietic Stem Cell Transplantation (MK-5119-001) (DEFLECT-1)

Clostridium Difficile-Associated Diarrhea (CDAD)
Coordinación de Investigación en Salud, Mexico

Completed

Prevention of Necrotizing Enterocolitis of Premature Newborns Under Less Than 1500 g Using Probiotics ((PEPP))

Infectious Diseases

Mexico

Clinical Trials on Clostridium Enterocolitis

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Mali

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Rare Diseases

Drug Interventions

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