Clinical Trials on Coenzyme Q10 Pharmacokinetics in Germany

Total 74 results

Grünenthal GmbH

Completed

Pharmacokinetic Characterization of Two Novel CG5503 Tablet Formulations in Healthy Volunteers

Pharmacokinetics

Germany
Bayer

Completed

Clinical Study Investigating the Conversion of the Contraceptive Compound Norethisterone Within the Body Towards the Contraceptive Compound Ethinylestradiol

Pharmacokinetics

Germany
UCB Pharma

Completed

The First Clinical Study to Test Safety, Blood Levels and Other Effects of CDP6038 in Healthy Males

Pharmacokinetics

Germany
Max-Planck-Institute of Psychiatry

Completed

Pharmacokinetic and Pharmacodynamic Effects of Escitalopram Depending on Genetic Polymorphisms of the ABCB1-gene

Pharmacokinetics

Germany
Central Institute of Mental Health, Mannheim

Terminated

Cannabidiol - an in Vivo Innovative Drug Delivery Study

Pharmacokinetics, Bioavailability

Germany
Bayer

Completed

Relative Bioavailability and Food Effect Study With Vericiguat to Characterize the Pediatric Formulation in Adult Healthy Subjects

Pharmacokinetics

Germany
Teva Branded Pharmaceutical Products R&D, Inc.

Completed

A Phase I Study in Young Healthy Women to Investigate the Effects of Laquinimod on Standard Oral Contraceptive When Both Treatments Are Given Together

Pharmacokinetics | Pharmacodynamics

Germany
AstraZeneca

Completed

Drug Interaction Study - Effect of AZD5672 on the Pharmacokinetics of Digoxin

Healthy Volunteers | Pharmacokinetics

Germany
Astellas Pharma Europe B.V.
Cubist Pharmaceuticals LLC

Completed

A Study to Assess the Effects of Multiple Doses of Fidaxomicin on a Single Dose of Rosuvastatin in Healthy Male Subjects

Healthy Subjects | Drug-Drug Interaction (DDI) | Intestinal Absorption | Pharmacokinetics of Rosuvastatin | Pharmacokinetics of Fidaxomicin

Germany
Bayer

Completed

Study of Finerenone to Investigate a Paediatric Formulation in Healthy Male Volunteers

Pharmacokinetics

Germany
Grünenthal GmbH

Completed

Investigation How CG5503 is Taken up and Excreted From the Body After 2 Minutes Intravenous Infusion With and Without Oral Co-administration of Charcoal

Pharmacokinetic

Germany
AstraZeneca

Completed

Clopidogrel Bioequivalence Study in Healthy Subjects

Bioequivalence, AUC, Cmax, Pharmacokinetics

Germany
Grünenthal GmbH

Completed

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of GRT9906 Prolonged Release Tablets After Dose Escalation in Healthy Subjects

Pharmacokinetics

Germany
Heidelberg University
Sanofi-Synthelabo

Completed

Bioavailability Investigations of Thyronajod Mite Tablets of Dosage Strengths 50 μg Levothyrox-ine/75 μg Iodine, and 100 μg Levothyroxine/75 μg Iodine vs. a Levothyroxine Drinking-Solution: A Randomised Cross Over Study in Healthy Male Individuals. Currently: 50 μg/ 75 μg Tablets

Pharmacokinetics

Germany
Heidelberg University
Sanofi-Synthelabo

Completed

Bioavailability Investigations of Thyronajod Mite Tablets of Dosage Strengths 50 μg Levothyrox-ine/75 μg Iodine, and 100 μg Levothyroxine/75 μg Iodine vs. a Levothyroxine Drinking-Solution: A Randomised Cross Over Study in Healthy Male Individuals. Currently: 100 μg/ 75 μg Tablets

Pharmacokinetics

Germany
IDEA AG

Completed

Multi-Centre, Open-Label, Two Segment, Study Comparing Plasma Pharmacokinetics of Ketoprofen in Diractin® Alone to Diractin® Applied Concomitant With Heat or Moderate Exercise

Pharmacokinetic

Germany
Astellas Pharma Europe B.V.
FibroGen

Completed

A Study to Evaluate the Effects of Multiple Doses of FG-4592 on the Exposure, Safety and Tolerability and Effect of Warfarin in Healthy Subjects

Healthy Subjects | Pharmacokinetics of FG-4592

Germany
Astellas Pharma Europe B.V.

Completed

A Study to Evaluate the Safety and Tolerability of YM150 in Healthy Caucasian and Japanese Male and Female Subjects, and to Assess the Effect That Gender May Have on Its Actions in the Body

Healthy Subjects | Pharmacokinetics | Pharmacodynamics | Japanese | Caucasian

Germany
Bayer

Completed

Study of Finerenone to Investigate a Paediatric Formulation in Healthy Male Subjects

Pharmacokinetics

Germany
Aker Biomarine Antarctic AS
BioTeSys GmbH

Completed

Uptake of an Omega-3 Oil in Healthy Adults

Pharmacokinetics | Absorption

Germany
Astellas Pharma Europe B.V.

Completed

Study to Evaluate the Effect of Solifenacin and Mirabegron on the Tamsulosin Hydrochloride (HCl) Concentrations in Blood in Healthy Male Subjects

Healthy Subjects | Pharmacokinetics | Drug-Drug Interaction (DDI)

Germany
University of Hohenheim

Active, not recruiting

The Microalga Phaeodactylum Tricornutum a Potential Fish Substitute?- Pharmacokinetic Study (MikroFisch)

Pharmacokinetic Parameters

Germany
Astellas Pharma Europe B.V.

Completed

Study to Evaluate the Effect of Solifenacin and Mirabegron on the Digoxin Concentrations in Blood in Healthy Subjects

Healthy Subjects | Pharmacokinetics | Drug-Drug Interaction (DDI)

Germany
Fraunhofer-Institute of Toxicology and Experimental...
AstraZeneca

Completed

Use of Exhaled Particles to Assess Lung Pharmacokinetics (EXPLORE)

Healthy | Lung Pharmacokinetic

Germany
Grünenthal GmbH

Completed

Clinical Study in Healthy Men to Investigate the Uptake of Buprenorphine and Its Elimination From the Body After Dermal Application as Patches for 96 Hours and for 72 Hours

Pain | Pharmacokinetics

Germany
Astellas Pharma Europe B.V.
Medivation, Inc.

Completed

A Study to Evaluate How a Drug That Alters Liver Enzymes (Rifampin) Affects the Metabolism of Enzalutamide in Men

Healthy Subjects | Drug-Drug Interaction (DDI) | Pharmacokinetics of Enzalutamide

Germany
University of Hohenheim

Completed

Comparison of Curcumin Bioavailability

Safety After Oral Intake | Pharmacokinetics After Oral Intake

Germany
University of Hohenheim

Completed

Bioavailability of Resveratrol From Vineatrol30 Extract Incorporated Into Micelles

Safety After Oral Intake | Pharmacokinetics After Oral Intake

Germany
University Medicine Greifswald

Not yet recruiting

Impact of Food Intake on Berberine Kinetics (BERKI-3)

Pharmacokinetic Study in Healthy Volunteers

Germany
University Medicine Greifswald

Recruiting

Sex Differences in Berberine Pharmacokinetics (BERKI-2)

Pharmacokinetic Study in Healthy Volunteers

Germany
University of Hohenheim
German Federal Ministry of Education and Research

Completed

Oral Bioavailability of Curcumin From Micronized Powder and Liquid Micelles in Healthy Young Women and Men

Pharmacokinetics of Novel Curcumin Formulations | Safety of Novel Curcumin Formulations

Germany
University Medicine Greifswald

Completed

Pharmacokinetic and Pharmacodynamic Interactions Between the Cholesterol-lowering Ezetimibe and the Non-nucleoside Reverse Transcriptase Inhibitor Efavirenz During Chronic Treatment in Healthy Volunteers With Reference to Intestinal Expression of CYP3A4, UGT1A1, ABCB1 and ABCC2

Pharmacokinetics | Pharmacodynamics | Drug Interactions | Intestinal Transporter Expression

Germany
University of Hohenheim
German Federal Ministry of Economics and Technology

Completed

Absorption and Excretion Kinetics of the Bioactive Ingredients of Rice Bran Extract

Safety After Oral Intake | Pharmacokinetics After Oral Intake

Germany
Astellas Pharma Europe B.V.

Completed

A Study to Assess the Interaction Between ASP1707 and Itraconazole in Healthy Female Subjects

Healthy Subjects | Pharmacokinetics | DDI (Drug-Drug Interaction)

Germany
University Medicine Greifswald

Completed

Impact of OCT1 and CYP2D6 Genotypes on Pharmacokinetics of Berberine in Healthy Volunteers (BERKI-1)

Pharmacokinetic Study in Healthy Volunteers

Germany
Grünenthal GmbH

Completed

Effect of a Multiple-dose Oral Administration of CG5503 PR on the Electrical Activity of the Heart in 48 Healthy Men and Women

Prolonged QTc Interval | Pharmacokinetic

Germany
Heidelberg University

Completed

Influence of Drug Transporter Expression on the Pharmacokinetics of the HIV Protease Inhibitor Kaletra

Healthy | Pharmacokinetics

Germany
University of Hohenheim
German Federal Ministry of Education and Research

Completed

Improved Oral Bioavailability of Curcumin Incorporated Into Micelles

Pharmacokinetics of New Curcumin Formulations | Safety of New Curcumin Formulations

Germany
Bayer

Completed

Drug-drug Interaction Study Using Rosuvastatin as a Breast Cancer Resistant Protein (Efflux Transporter), Organic Anion-transporting Polypeptide (OATP)1B1, and OATP1B3 (Uptake Transporters) Probe Substrate

Healthy Volunteers | Pharmacokinetics | Drug Interaction

Germany
CannaXan GmbH

Completed

Clinical Trial on Pharmacokinetics and Tolerability of AP707

Pharmacokinetics | Tolerability | Safety

Germany
University Medicine Greifswald
AWD.pharma GmbH & Co. KG

Completed

Pharmacokinetics, Metabolism and Analgesic Effects of Flupirtine

Pain | Pharmacokinetics | Flupirtine

Germany
University of Hohenheim
Universität Tübingen

Completed

Oral Bioavailability and Bioactivity of Prenylflavonoids From Hops

Safety After Oral Intake | Pharmacokinetics After Oral Intake | Immune Cells Activity

Germany
University Medicine Greifswald

Completed

Influence of the OATP1B1 and OATP1B3 Genotype on the Hepatic Uptake of Primovist®

MRI | Pharmacokinetics | Liver | Drug Transporter | Gd-EOB-DTPA

Germany
CannaXan GmbH

Completed

Clinical Trial on Pharmacokinetic and Tolerability of AP701

Tolerability | Safety | Pharmacokinetic

Germany
Bayer
Janssen Research & Development, LLC

Completed

Relative Bioavailability Study in Healthy Subjects Comparing 2 Dry Powder Oral Suspensions of Rivaroxaban Under Fasting and 20 mg of an Oral Suspension of Rivaroxaban Under Fed Conditions to 10 mg of an Immediate Release Tablet Under Fasting Conditions

Pharmacokinetics

Germany
University Medicine Greifswald

Completed

Pharmacokinetic Drug Interaction Between Ezetimibe and Sirolimus After Single Dose Administration in Healthy Subjects

Hypercholesterolemia | Pharmacokinetics | Immunosuppression | Drug Interactions

Germany
Bayer

Completed

Study to Investigate Safety, Absorption, Elimination, and Drug Effect of BAY2327949 in Participants With Different Renal Function Status

Pharmacokinetics

Germany
University Medicine Greifswald

Completed

Pharmacokinetic Drug Interaction Between Ezetimibe and Tacrolimus After Single Dose Administration in Healthy Subjects

Hypercholesterolemia | Pharmacokinetics | Immunosuppression | Drug Interactions

Germany
Novartis Pharmaceuticals

Completed

Comparison of a Tacrolimus Hexal® Based Regimen Versus a Prograf® Based Regimen in de Novo Renal Transplant Recipients (Spartacus)

Pharmacokinetics Study in de Novo Kidney Transplantation

Germany
Heidelberg University

Completed

Pharmacokinetics of THCCOOH and Its Acyl-glucuronide After Intravenous Administration of THCCOOH

Pharmacokinetics | Cannabis | Metabolism | THCCOOH

Germany

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