Clinical Trials on Colorectal Neoplasm

Total 107032 results

Fondazione IRCCS Istituto Nazionale dei Tumori,...
Azienda Usl di Bologna

Completed

Adjuvant HIPEC to Prevent Colorectal Peritoneal Metastases in High-risk Patients

Colorectal Neoplasm | Metastasis
Academisch Medisch Centrum - Universiteit van Amsterdam...

Completed

Combining Risk Factors and Faecal Immunochemical Testing in Colorectal Cancer Screening: a Randomized Controlled Trial

Colorectal Neoplasms | Colorectal Cancer | Colorectal Adenoma | Colorectal Carcinoma | Colorectal Adenoma and Carcinoma

Netherlands
Fundació Institut Germans Trias i Pujol
Hospital General Universitario Gregorio Marañon; Hospital Clinic of Barcelona; Hospital General Universitario Elche and other collaborators

Unknown

Endoscopic Full-Thickness Resection In Colon (EFTRICOM)

Colorectal Neoplasms | Colorectal Cancer | Colo-rectal Cancer | Colonic Cancer | Colorectal Adenocarcinoma | Colon Polyp | Colon Neoplasm, Malignant | Colonic Adenoma | Colon Lesion | Colon Neoplasm

Spain
Academic and Community Cancer Research United
National Cancer Institute (NCI)

Active, not recruiting

Capecitabine and Bevacizumab With or Without Atezolizumab in Treating Patients With Refractory Metastatic Colorectal Cancer

Stage IV Colorectal Cancer AJCC v7 | Stage IVA Colorectal Cancer AJCC v7 | Stage IVB Colorectal Cancer AJCC v7 | Recurrent Colorectal Carcinoma | Metastatic Colorectal Carcinoma | Refractory Colorectal Carcinoma

United States
Martin-Luther-Universität Halle-Wittenberg
University of Ulm; Deutsche Krebshilfe e.V., Bonn (Germany); KKS Netzwerk

Completed

Minimizing the Risk of Metachronous Adenomas of the Colorectum With Green Tea Extract -MIRACLE- (MIRACLE)

Colorectal Serrated Adenomas | Colorectal Tubular Adenomas | Colorectal Villous Adenomas | Colorectal Tubulovillous Adenomas

Germany
Vastra Gotaland Region

Recruiting

The Swedish Study of Liver Transplantation for Non-resectable Colorectal Cancer Metastases (SOULMATE)

Colorectal Cancer | Liver Metastases | Colorectal Liver Metastases

Sweden
Fudan University

Unknown

Study Comparing Radio Frequency Ablation Plus Chemotherapy and Chemotherapy Alone in Patients With Unresectable CRLM

Colorectal Cancer Liver Metastasis

China
University of Southern California
National Cancer Institute (NCI)

Completed

Collection of Blood, Urine, and Stool to Monitor MetastaticColorectal Cancers

Stage IV Colorectal Cancer AJCC v8 | Stage IVA Colorectal Cancer AJCC v8 | Stage IVB Colorectal Cancer AJCC v8 | Stage IVC Colorectal Cancer AJCC v8 | Stage III Colorectal Cancer AJCC v8 | Stage IIIA Colorectal Cancer AJCC v8 | Stage IIIB Colorectal Cancer AJCC v8 | Stage IIIC Colorectal Cancer AJCC...

United States
Roswell Park Cancer Institute

Not yet recruiting

Pembrolizumab and Autologous Dendritic Cells for the Treatment of Refractory Colorectal Cancer (CRC)

Recurrent Colorectal Carcinoma | Stage IV Colorectal Cancer AJCC v8 | Stage III Colorectal Cancer AJCC v8 | Unresectable Colorectal Carcinoma | Metastatic Microsatellite Stable Colorectal Carcinoma

United States
Weill Medical College of Cornell University
Agenus Inc.

Recruiting

Platform Study of Immunotherapy Combinations in Colorectal Cancer Liver Metastases

Colorectal Cancer | Colorectal Cancer Metastatic | Liver Metastases

United States
Fudan University

Not yet recruiting

Multimodal Model for Efficacy Prediction Cetuximab in Colorectal Cancer Liver Metastasis Patient

Colorectal Cancer Liver Metastases

China
Peking Union Medical College Hospital
Cancer Institute and Hospital, Chinese Academy of Medical Sciences; Peking... and other collaborators

Recruiting

3D Bioprinted Models for Predicting Chemotherapy Response in Colorectal Cancer With/Without Liver Metastases

Colorectal Cancer | Colorectal Cancer Liver Metastasis

China
University of Southern California
National Cancer Institute (NCI)

Terminated

Medical and Psychosocial Issues in Adolescents and Young Adults With Colorectal Cancer

Stage IV Colorectal Cancer AJCC v8 | Stage IVA Colorectal Cancer AJCC v8 | Stage IVB Colorectal Cancer AJCC v8 | Stage IVC Colorectal Cancer AJCC v8 | Stage III Colorectal Cancer AJCC v8 | Stage IIIA Colorectal Cancer AJCC v8 | Stage IIIB Colorectal Cancer AJCC v8 | Stage IIIC Colorectal Cancer AJCC... and other conditions

United States
Western Sydney Local Health District

Recruiting

ESD for Colorectal LSL Using a Selective Strategy - a Prospective Cohort Study (COVERT)

Colorectal Neoplasm | Endoscopic Mucosal Resection

Australia
University of Michigan Rogel Cancer Center
National Cancer Institute (NCI)

Not yet recruiting

A Trial of Omeprazole and Low Dose Aspirin to Identify Colorectal Biomarkers of Preventive Efficacy

Colorectal Neoplasia

United States
M.D. Anderson Cancer Center

Active, not recruiting

Glutamine PET Imaging Colorectal Cancer

Stage IV Colorectal Cancer | Stage IVA Colorectal Cancer | Stage IVB Colorectal Cancer | RAS Wild Type

United States
Roswell Park Cancer Institute
National Cancer Institute (NCI); Merck Sharp & Dohme LLC

Completed

Cetuximab and Pembrolizumab in Treating Patients With Colorectal Cancer That is Metastatic or Cannot Be Removed by Surgery

Recurrent Colorectal Carcinoma | Stage IVA Colorectal Cancer | Stage IVB Colorectal Cancer

United States
City of Hope Medical Center
National Cancer Institute (NCI)

Terminated

FOLFIRI and Panitumumab in Treating Patients With RAS and BRAF Wild-Type Metastatic Colorectal Cancer

Recurrent Colorectal Carcinoma | Stage IVA Colorectal Cancer | Stage IVB Colorectal Cancer

United States
University of Wisconsin, Madison
Merck Sharp & Dohme LLC

Completed

PI Pembro in Combination With Stereotactic Body Radiotherapy for Liver Metastatic Colorectal Cancer

Colorectal Cancer | Colorectal Adenocarcinoma | Stage IVA Colorectal Cancer | Stage IVB Colorectal Cancer | Metastatic Carcinoma in the Liver

United States
Academic and Community Cancer Research United
National Cancer Institute (NCI)

Completed

Irinotecan and Cetuximab With or Without Bevacizumab in Treating Patients With RAS Wild-Type Locally Advanced or Metastatic Colorectal Cancer That Cannot Be Removed by Surgery

Stage IV Colorectal Cancer AJCC v7 | Stage IVA Colorectal Cancer AJCC v7 | Stage IVB Colorectal Cancer AJCC v7 | Colorectal Adenocarcinoma | RAS Wild Type

United States
Bristol-Myers Squibb

Active, not recruiting

A Study of Nivolumab Alone or Nivolumab Combination Therapy in Colon Cancer That Has Come Back or Has Spread (CheckMate142)

Microsatellite Stable Colorectal Cancer | Mismatch Repair Proficient Colorectal Cancer | Microsatellite Unstable Colorectal Cancer | Mismatch Repair Deficient Colorectal Cancer

United States, Australia, Belgium, Canada, Ireland, Italy, Spain, France
Fudan University

Recruiting

Fruquintinib Combined With TAS-102 in Refractory Metastatic Colorectal Cancer

Metastatic Colorectal Cancer | Colorectal Cancer | Refractory Colorectal Carcinoma

China
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

4D PET/CT in Diagnosing Participants With Lung and Colorectal Cancer With Liver and Lung Metastasis

Stage IVA Lung Cancer AJCC v8 | Stage IVB Lung Cancer AJCC v8 | Stage IV Lung Cancer AJCC v8 | Metastatic Malignant Neoplasm in the Liver | Stage IV Colorectal Cancer AJCC v8 | Stage IVA Colorectal Cancer AJCC v8 | Stage IVB Colorectal Cancer AJCC v8 | Stage IVC Colorectal Cancer AJCC v8 | Metastatic...

United States
Academisch Medisch Centrum - Universiteit van Amsterdam...
University of Bologna; Bergman Clinics

Completed

Evaluation of a New Blood-based Test to Detect Colorectal Cancer and Its Precursors (CELTiC)

Colorectal Neoplasms | Colorectal Cancer | Colorectal Adenoma | Colorectal Carcinoma | Colorectal Polyp

Netherlands, Italy
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Completed

Systems Support Mapping in Guiding Self-Management in Stage I-III Colorectal Cancer Survivors

Cancer Survivor | Stage III Colorectal Cancer AJCC v8 | Stage IIIA Colorectal Cancer AJCC v8 | Stage IIIB Colorectal Cancer AJCC v8 | Stage IIIC Colorectal Cancer AJCC v8 | Stage I Colorectal Cancer AJCC v8 | Stage II Colorectal Cancer AJCC v8 | Stage IIA Colorectal Cancer AJCC v8 | Stage IIB Colorectal... and other conditions

United States
Leap Therapeutics, Inc.

Recruiting

Phase 2 Study of DKN-01 in Colorectal Cancer (DeFianCe)

Colorectal Cancer | Colorectal Cancer Metastatic | Colo-rectal Cancer | Colorectal Adenocarcinoma

United States, Korea, Republic of, Germany
Milton S. Hershey Medical Center

Completed

Detection of CTCs in Patients Undergoing Surgery for Stage IV Colorectal Cancer

Lung Metastases | Liver Metastases | Stage IV Colorectal Cancer

United States
Gachon University Gil Medical Center

Completed

Prospective Phase II Trial on Prophylactic Perihepatic Lymphadenectomy in Patients With Colorectal Cancer With Liver Metastasis (LN)

Colorectal Cancer With Liver Metastasis

Korea, Republic of
University of California, San Francisco
Merck Sharp & Dohme LLC

Completed

Pembrolizumab, Capecitabine, and Bevacizumab in Treating Patients With Microsatellite Stable Colorectal Cancer That Is Locally Advanced, Metastatic, or Cannot Be Removed by Surgery

Stage IV Colorectal Cancer AJCC v7 | Stage IVA Colorectal Cancer AJCC v7 | Stage IVB Colorectal Cancer AJCC v7 | Microsatellite Stable | Stage III Colorectal Cancer AJCC v7 | Stage IIIB Colorectal Cancer AJCC v7 | Stage IIIC Colorectal Cancer AJCC v7 | Mismatch Repair Protein Proficient

United States
Ludwig-Maximilians - University of Munich
Charité Universitätsmedizin, Department of Hematology, Oncology and Tumor...

Not yet recruiting

Centralized Tumour Board and Secondary Intervention Rate in mCRC

Metastatic Colorectal Cancer | Multidisciplinary Communication | RAS Mutation | Secondary Intervention
GERCOR - Multidisciplinary Oncology Cooperative...
Bristol-Myers Squibb

Recruiting

Two Combination Treatment Regimens of Nivolumab and Ipilimumab in Patients With dMMR and / or MSI mCRC. (NIPISAFE)

Colorectal Cancer Metastatic | MSI-H Colorectal Cancer

France
Academic and Community Cancer Research United
National Cancer Institute (NCI)

Active, not recruiting

Binimetinib and Palbociclib or TAS-102 in Treating Patients With KRAS and NRAS Mutant Metastatic or Unresectable Colorectal Cancer

Metastatic Colorectal Carcinoma | Stage IV Colorectal Cancer AJCC v8 | Stage IVA Colorectal Cancer AJCC v8 | Stage IVB Colorectal Cancer AJCC v8 | Stage IVC Colorectal Cancer AJCC v8 | Unresectable Carcinoma

United States
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Active, not recruiting

Chemotherapy and/or Metastasectomy in Treating Patients With Metastatic Colorectal Adenocarcinoma With Lung Metastases

Colorectal Adenocarcinoma | Stage IV Colorectal Cancer AJCC v8 | Stage IVA Colorectal Cancer AJCC v8 | Stage IVB Colorectal Cancer AJCC v8 | Stage IVC Colorectal Cancer AJCC v8 | Colorectal Carcinoma Metastatic in the Lung

United States, Canada
Nyamdavaa Tuul

Not yet recruiting

Phase I Study of Combined Immune Cell Therapy in Patients With Stage 4 Colorectal Cancer With Metastatic Lesion Who Failed Prior Standard of Care

Metastatic Colorectal Cancer | Colorectal Cancer Stage IV
City of Hope Medical Center
National Cancer Institute (NCI)

Active, not recruiting

An Imaging Agent (I-124 M5A) in Detecting CEA-Positive Liver Metastases in Patients With Colorectal Cancer

Metastatic Colorectal Carcinoma | Stage IV Colorectal Cancer AJCC v8 | Stage IVA Colorectal Cancer AJCC v8 | Stage IVB Colorectal Cancer AJCC v8 | Stage IVC Colorectal Cancer AJCC v8 | Colorectal Carcinoma Metastatic in the Liver

United States
Zhejiang University

Suspended

Randomized Trial of Primary Surgery Followed Selective Radiochemotherapy for Rectal Cancer With MRI Negative CRM (PSSR)

Surgery | Colorectal Neoplasm | Effects of Chemotherapy | Effects of Radiation Therapy

China
Xijing Hospital
Air Force Military Medical University, China

Unknown

Colorectal Polyps Screening With Low-dose CT Colonoscopy

Polyps | Colorectal Neoplasm

China
MiWEndo Solutions S.L.

Recruiting

Performance and Safety of MiWEndo-assisted Colonoscopy (MiWEndo II)

Colorectal Neoplasms | Colorectal Cancer | Colorectal Adenoma | Colorectal Adenocarcinoma | Colorectal Polyp | Colorectal Adenomatous Polyp

Spain
Shanghai Minimally Invasive Surgery Center

Active, not recruiting

Infrapyloric and Greater Curvature Lymph Node Metastasis in Colon Cancer

Colorectal Neoplasm

China
MiWEndo Solutions S.L.
Hospital Clinic of Barcelona

Completed

Feasibility and Safety of MiWEndo-assisted Colonoscopy (MiWEndo1)

Colorectal Neoplasms | Colorectal Cancer | Colorectal Adenoma | Colorectal Adenocarcinoma | Colorectal Polyp | Colorectal Adenomatous Polyp

Spain
Alliance for Clinical Trials in Oncology
National Cancer Institute (NCI)

Recruiting

Testing the Addition of Total Ablative Therapy to Usual Systemic Therapy Treatment for Limited Metastatic Colorectal Cancer, The ERASur Study

Metastatic Colorectal Adenocarcinoma | Stage IV Colorectal Cancer AJCC v8

United States
Harbin Medical University

Not yet recruiting

A Trial of Camrelizumab Combined With Microwave Ablation and Chemotherapy in the Treatment of Colorectal Cancer Liver Metastasis/Pulmonary Metastasis

Lung Metastases | Colorectal Cancer Metastatic | Liver Metastases
Oslo University Hospital
The Research Council of Norway; Norwegian Cancer Society; Klinbeforsk

Active, not recruiting

Aspirin in Colorectal Cancer Liver Metastases (ASAC)

Colorectal Cancer | Liver Metastases | Colorectal Cancer Liver Metastases

Norway, Denmark, Sweden
Fudan University

Unknown

A Model for Predicting the Efficacy of Conversion Therapy for Patients With Colorectal Cancer Liver Metastases by the Detection of 5-hydroxymethylcytosine (5-hmC) in Plasma Cell-free DNA

Colorectal Cancer With Liver Metastases

China
Fudan University

Completed

Postoperative Folfox4 Only Versus Folfox4 Plus Transhepatic Arterial Chemotherapy (TAC) in the Treatment Unresectable Liver Metastasis of Colorectal Cancer

Unresectable Liver Metastasis of Colorectal Cancer

China
Sun Yat-sen University

Recruiting

Regorafenib Combined With Irinotecan Drug-Eluting Beads for Colorectal Cancer Liver Metastases (RIDER)

Colorectal Cancer Liver Metastases | Regorafenib

China
Ye Xu

Unknown

Alternating Systemic and Hepatic Artery Infusion Therapy As Adjuvant Treatment After Resection of Liver Metastases From Colorectal Cancer

Resected Liver Metastases From Colorectal Cancer

China
BioNTech SE

Recruiting

Epidemiological Study to Monitor Study Participants With Resected Stage II (High Risk) or Stage III Colorectal Cancer for Circulating Tumor DNA Before, During and After Their Treatment With Adjuvant Chemotherapy

Colorectal Cancer Stage II | Colorectal Cancer Stage III

United States, Spain, Germany, Belgium
BioNTech SE
Genentech, Inc.

Recruiting

A Phase II Clinical Trial Comparing the Efficacy of RO7198457 Versus Watchful Waiting in Patients With ctDNA-positive, Resected Stage II (High Risk) and Stage III Colorectal Cancer

Colorectal Cancer Stage II | Colorectal Cancer Stage III

United States, Spain, United Kingdom, Germany, Belgium, Sweden
Shanghai Jiao Tong University School of Medicine
Fudan University; Shanghai Zhongshan Hospital; Ruijin Hospital; Shanghai Municipal... and other collaborators

Recruiting

Study of Oral Metronidazole on Postoperative Chemotherapy in Colorectal Cancer

Colorectal Cancer Stage II | Colorectal Cancer Stage III

China

Clinical Trials on Colorectal Neoplasm

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