Clinical Trials on Critical Limb Ischemia

Total 17078 results

Pluristem Ltd.

Unknown

Efficacy, Tolerability and Safety of Intramuscular Injections of PLX PAD for the Treatment of Subjects With Critical Limb Ischemia (CLI) With Minor Tissue Loss Who Are Unsuitable for Revascularization

Critical Limb Ischemia (CLI)

Germany, United Kingdom, Hungary, United States, Bulgaria, Czechia, Israel, North Macedonia, Poland
Temple University

Unknown

External Compression Therapy for Secondary Prevention of Lower-Limb Loss and Cardiovascular Mortality (ArtAssist)

Critical Limb Ischemia

United States
Biotyx Medical (Shenzhen) Co., Ltd.

Recruiting

IBS Titan vs. PTA in Patients With Infrapopliteal Arterial Stenosis or Occlusive Disease (GENIUS)

Critical Limb Ischemia (CLI)

China
Egyptian Biomedical Research Network

Completed

Surgical Bypass Versus Hybrid Approaches for Critical Limb Ischemia

Critical Lower Limb Ischemia
Andalusian Initiative for Advanced Therapies -...
Iniciativa Andaluza en Terapias Avanzadas

Terminated

Clinical Trial I/II Opened, Randomized and Controlled for the Study of the Use of Stem Cells Therapy in Insulinized Diabetic Patients Type 2 With Critical Ischemia in Lower Limbs (CLI): Study of the Needs of Insulin

Critical Limb Ischemia (CLI)

Spain
Medtronic Endovascular

Completed

Study of IN.PACT Amphirion™ Drug Eluting Balloon vs. Standard PTA for the Treatment of Below the Knee Critical Limb Ischemia (INPACT-DEEP)

Critical Lower Limb Ischemia

Germany, Belgium, Netherlands, Switzerland, Austria, Italy
Pluristem Ltd.

Available

Expanded Access Treatment of Subjects With Critical Limb Ischemia (CLI) With Minor Tissue Loss Who Are Unsuitable for Revascularization

Critical Limb Ischemia (CLI)

United States
WideTrial, Inc.

Available

Expanded Access for Treatment Use of PLX-PAD in Critical Limb Ischemia (CLI)

Critical Limb Ischemia (CLI)
Cesca Therapeutics, Inc.

Unknown

Critical Limb Ischemia Rapid Delivery by SurgWerks-CLI Kit and VXP System (CLIRST III)

Critical Limb Ischemia (CLI)
University Hospital, Angers

Not yet recruiting

NOrmoBaric Oxygen Therapy Use In Critical Limb ISchemia (NOBILIS)

Critical Ischemia Limb

France
Abbott Medical Devices

Active, not recruiting

LIFE-BTK PK Sub-study

Critical Limb Ischemia (CLI)

Taiwan, United States, Australia
Abbott Medical Devices

Active, not recruiting

LIFE-BTK Randomized Controlled Trial (LIFE-BTK)

Critical Limb Ischemia (CLI)

United States, Hong Kong, Australia, New Zealand, Singapore, Taiwan
Xuanwu Hospital, Beijing

Recruiting

Excimer Laser Combined With DCB Compared With Angioplasty Alone in the Treatment of Infrapopliteal Lesions.

Critical Limb Ischemia | Infrapopliteal Lesions

China
National University of Malaysia
Cytopeutics Sdn. Bhd.

Unknown

Intramuscular Mononuclear Cells and Mesenchymal Stem Cells Transplantation to Treat Chronic Critical Limb Ischemia

Critical Limb Ischemia

Malaysia
Andalusian Initiative for Advanced Therapies -...
Iniciativa Andaluza en Terapias Avanzadas

Completed

Application of Cell Regeneration Therapy With Mesenchymal Stem Cells From Adipose Tissue in Critical Chronic Ischemic Syndrome of Lower Limbs (CLI) in Nondiabetic Patients.

Critical Limb Ischemia

Spain
Ospedale San Donato

Unknown

Comparison of Sirolimus vs Paclitaxel Drug Eluting Balloon for Below-the-knee Angioplasty in Critical Limb Ischemia (DebateBTKDuell)

Drug Effect | Critical Limb Ischemia

Italy
Assiut University

Not yet recruiting

Outcomes of Endovascular Revascularization in CLTI in Patients Associated With Heel Ulcers

Lower Limb Ischemia Critical
Stanford University
National Heart, Lung, and Blood Institute (NHLBI); Medtronic Endovascular

Enrolling by invitation

The Use of FlowMet-R Technology to Predict Wound Healing in CLI Patients in a Wound Care Center Setting

Critical Limb Ischemia

United States
Andalusian Initiative for Advanced Therapies -...
Iniciativa Andaluza en Terapias Avanzadas

Completed

Intra-arterial Infusion of Autologous Bone Marrow Mononuclear Cells in Non-diabetic Patients With Critical Limb Ischemia (CLI).

Critical Limb Ischemia (CLI)

Spain
Southwest Regional Wound Care Center

Completed

A Retrospective Analysis of Patients With Full Thickness Wounds in Limbs With Critical Ischemia

Critical Limb Ischemia

United States
Micro Medical Solution, Inc.

Recruiting

An All-Comers Observational Study of the MicroStent™ Peripheral Vascular Stent System in Subjects With Peripheral Arterial Disease (HEAL)

Peripheral Arterial Disease | Peripheral Artery Disease | Critical Limb Ischemia | Critical Lower Limb Ischemia

Austria, Belgium, Germany, Italy, Netherlands
Science Valley Research Institute
Wyeth is now a wholly owned subsidiary of Pfizer

Recruiting

Efficacy and Safety of Apixaban in Reducing Restenosis and Limb Loss in PAD Patients. (AGRIPPA)

Critical Limb Ischemia

Brazil
TotipotentSC Scientific Product Pvt. Ltd.
Thermogenesis Corp.

Completed

Safety and Efficacy of Autologous Bone Marrow Mononuclear Cells in Patients With Severe Critical Limb Ischemia

Critical Limb Ischemia

India
University of Illinois at Chicago

Completed

Proteomics and Stem Cell Therapy as a New Vascularization Strategy

Critical Limb Ischemia

United States
Yonsei University

Unknown

Comparison of Cilostazol-based Triple Antiplatelet Therapy Versus Dual Antiplatelet Therapy for Outcomes of below-the Knee Endovascular Intervention in Patients With Critical Limb Ischemia (TAP CLI Study)

Critical Limb Ischemia

Korea, Republic of
Juventas Therapeutics, Inc.

Completed

Study to Evaluate the Safety and Efficacy of JVS-100 Administered to Adults With Critical Limb Ischemia

Critical Limb Ischemia

United States, India
Southern Arizona Vascular Institute
Southern Illinois University

Unknown

UT-15C SR in the Treatment of Critical Limb Ischemia

Critical Limb Ischemia

United States
Kafrelsheikh University

Active, not recruiting

Outcomes of Straight-line Flow Versus Angiosome-targeted Angioplasty in Treatment of Critical Lower Limb Ischemia

Critical Lower Limb Ischemia | Angioplasty

Egypt
Ochsner Health System
United Therapeutics

Completed

Safety Study of UT-15C SR (Oral Treprostinil) in Patients Undergoing a Lower Limb Endovascular Procedure

Critical Limb Ischemia

United States
University Hospital, Angers

Completed

New Oxymetry Indices in Critical Limb Ischemia (NOVICE)

Critical Limb Ischemia

France
Vericel Corporation

Completed

An Efficacy and Safety Study of Ixmyelocel-T in Patients With Critical Limb Ischemia (CLI) (REVIVE)

Critical Limb Ischemia

United States
Cook Research Incorporated

Terminated

HemaTrate™ in the Treatment of Critical Limb Ischemia

Ischemia | Critical Limb Ischemia

United Kingdom
Helixmith Co., Ltd.

Completed

Safety and Efficacy Study Using Gene Therapy for Critical Limb Ischemia

Critical Limb Ischemia

United States, Korea, Republic of
Helixmith Co., Ltd.

Completed

Safety Study of Gene Therapy in Treating Lower Leg Ischemia

Critical Limb Ischemia

United States
The Cleveland Clinic

Withdrawn

Correlation Between FlowMet™ and Other Gold Standard Assessments in the Management of Critical Limb Ischemia (CLI)

Critical Limb Ischemia

United States
Richard Burt, MD

Terminated

Efficacy and Safety of Umbilical Cord Blood Injection for Critical Limb Ischemia

Critical Limb Ischemia

United States
Clinical Centre of Serbia
University of California, Los Angeles

Unknown

Distal Venous Arterialisation of Ischemic Limb

Critical Limb Ischemia

Serbia
University of Manitoba
Mitsubishi-Rayon-Cleansui

Unknown

Evaluation of Carbothera in the Treatment of Foot Ulcers

Foot Ulcer | Critical Limb Ischemia | Critical Lower Limb Ischemia | Skin Ulceration

Canada
Ryazan State Medical University

Recruiting

Allografts in Surgery of the Main Arteries

Critical Lower Limb Ischemia

Russian Federation
University of Catanzaro

Completed

Matrix Metalloproteinases in Patients With Critical Limb Ischemia Undergoing Surgical Revascularization (ROMAMETA)

Critical Limb Ischemia | Extracellular Matrix Alteration | Peripheral Revascularisation
Mahidol University

Completed

Treatment of Chronic Critical Limb Ischemia With G-CSF-mobilized Autologous Peripheral Blood Mononuclear Cells

Atherosclerosis | Gangrene | Critical Limb Ischemia | Ischemic Ulcer

Thailand
IRCCS Policlinico S. Matteo

Completed

Autologous Endothelial Progenitor Cells (EPCs) From Peripheral Blood in the Treatment of Critical Limb Ischemia

Critical Limb Ischemia

Italy
University of Oklahoma
Atrium Medical Corporation

Terminated

Use of Clearway™ Balloon vs. Mechanical Thrombectomy as Initial Treatment for Acute Limb Ischemia

Critical Limb Ischemia

United States
Center of New Medical Technologies

Not yet recruiting

Nanofat Grafting as a Method of Treating Critical Limb Ischemia

Limb Ischemia

Russian Federation
Ageless Regenerative Institute

Withdrawn

Autologous Adipose-Derived Stromal Cell Delivered Via Intramuscular Injections for the Treatment of Critical Limb Ischemia

Critical Limb Ischemia

United States
Vascular Investigation Network Spanish Society...
Hospital Clínico Universitario de Valladolid

Completed

Impact of Nutritional and Inflammatory Status in Patients With Critical Limb-threatening Ischemia

Postoperative Complications | Critical Lower Limb Ischemia

Spain
LimFlow, Inc.

Active, not recruiting

PROMISE II: Percutaneous Deep Vein Arterialization for the Treatment of Late-Stage Chronic Limb-Threatening Ischemia (PROMISE)

Vascular Diseases | Arterial Occlusive Diseases | Peripheral Arterial Disease | Peripheral Vascular Disease | Peripheral Artery Disease | Critical Limb Ischemia | Arterial Disease | Arterial Occlusion | Critical Lower Limb Ischemia | Chronic Limb-Threatening Ischemia | Peripheral Artery Occlusion | Peripheral...

United States, Puerto Rico
Hull University Teaching Hospitals NHS Trust

Completed

Peripheral Vascular Disease and Nerve Stimulation (CCLINS)

Varicose Veins | Claudication | Ulcers | Critical Limb Ischaemia | Post Angioplasty

United Kingdom
HealthCore-NERI
Massachusetts General Hospital; National Heart, Lung, and Blood Institute (NHLBI) and other collaborators

Completed

Best Endovascular vs. Best Surgical Therapy in Patients With Critical Limb Ischemia (BEST-CLI)

Critical Limb Ischemia

United States, Canada, New Zealand, Finland, Italy
Mahmoud Abdelmohsen Mostafa Osman

Not yet recruiting

Role and Outcome of Endovascular Revascularization of Chronic Limb Ischaemia

Limb Ischemia, Critical

Clinical Trials on Critical Limb Ischemia

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