Clinical Trials on Cryptococcosis or Aspergillosis Infections in United Kingdom

Total 1083 results

F2G Biotech GmbH
Quotient Clinical

Completed

Evaluation of Immediate Release Tablet

Invasive Aspergillosis

United Kingdom
F2G Biotech GmbH
Hammersmith Medicines Research

Completed

Evaluation of the Potential for Cytochrome P450 3A4 Inhibition by F901318 Using Oral Midazolam as a Probe

Invasive Aspergillosis

United Kingdom
Zambon SpA

Completed

Phase 1 Three Part SAD, MAD & Cross-Over Study of ZP-059 in Healthy and Asthmatic Subjects

Allergic Bronchopulmonary Aspergillosis

United Kingdom
F2G Biotech GmbH
Quotient Clinical

Withdrawn

Radiolabelled IV and Oral Metabolism Study of F901318 (ADME)

Invasive Aspergillosis

United Kingdom
F2G Biotech GmbH
Hammersmith Medicines Research

Completed

F901318 Multiple Ascending Dose Study

Invasive Aspergillosis

United Kingdom
F2G Biotech GmbH
Celerion Ltd

Completed

Study of Potential for Interaction of Fluconazole With F901318

Invasive Aspergillosis

United Kingdom
F2G Biotech GmbH
Simbec-Orion Group

Completed

Single Ascending Oral Dose Study of F901318

Invasive Aspergillosis

United Kingdom
Community Pharmacology Services Ltd
Pulmatrix Inc.

Withdrawn

Allergic Bronchopulmonary Aspergillosis Prescreening Study

Asthma | Allergic Bronchopulmonary Aspergillosis | ABPA

United Kingdom
F2G Biotech GmbH
Covance

Completed

Assessment of Varying Oral Dosing Regimens for F901318 in Healthy Subjects

Invasive Aspergillosis

United Kingdom
F2G Biotech GmbH
SimbecRresearch Ltd.

Completed

Multiple Ascending Oral Dose Study of F901318 in Healthy Subjects (ORALMAD)

Invasive Aspergillosis

United Kingdom
F2G Biotech GmbH
Simbec Research

Completed

F901318 Single Ascending Dose Study in Healthy Male Volunteers

Invasive Aspergillosis

United Kingdom
St George's University Hospitals NHS Foundation...
University College, London; St George's, University of London; University of... and other collaborators

Recruiting

LFD of Aspergillus Antigen in Paediatrics (LFD-AsPaeds)

Invasive Pulmonary Aspergillosis | Invasive Fungal Disease

United Kingdom
Novartis Pharmaceuticals

Terminated

An Exploratory Study to Assess Multiple Doses of Omalizumab in Patients With Cystic Fibrosis Complicated by Acute Bronchopulmonary Aspergillosis (ABPA)

Cystic Fibrosis | Allergic Bronchopulmonary Aspergillosis

United Kingdom, Germany, Belgium, Italy, Netherlands
King's College Hospital NHS Trust

Completed

Diagnostic and Management Strategies for Invasive Aspergillosis

Neutropenia | Invasive Aspergillosis

United Kingdom
University of Colorado, Denver
University of California, Davis; University of Georgia

Recruiting

Prospective Observational Study on the Incidence of Opportunistic Fungal Infections

Candidiasis | Aspergillosis | Cryptococcosis | Pneumocystis Jirovecii Infection | Pneumocystis

United States
Pulmocide Ltd

Terminated

The Effect of Early Treatment of PC945 on Aspergillus Fumigatus Lung Infection in Lung Transplant Patients.

Aspergillosis | Lung Transplant Infection

United Kingdom
University of Alabama at Birmingham
University of Colorado, Denver

Completed

Immune Profiles in CF Fungal Infection

Fungal Infection | Cystic Fibrosis | Allergic Bronchopulmonary Aspergillosis

United States
Pfizer

Completed

Patterns of Real-World Isavuconazole Use - a Study of Patients With Mucormycosis or Invasive Aspergillosis (PRISMA)

Mucormycosis | Invasive Aspergillosis

Spain, Germany, France, United Kingdom, Italy
Brynn Chappell
The Christie NHS Foundation Trust

Suspended

Individualisation of Voriconazole Antifungal Therapy Antifungal Therapy (PIVOTAL)

Aspergillosis | Immunocompromised Patient | Fusarium

United Kingdom
Medstar Health Research Institute
Enzon Pharmaceuticals, Inc.

Withdrawn

Safety, Efficacy, and Pharmacokinetics of Amphotericin B Lipid Complex

Invasive Cryptococcosis

United States
Pulmatrix Inc.

Terminated

Study in Adult Asthmatic Patients With Allergic Bronchopulmonary Aspergillosis

Allergic Bronchopulmonary Aspergillosis

United States, Australia, United Kingdom, India, Poland
National Cancer Institute (NCI)

Completed

Evaluation of the Association of Polymorphisms in the Innate Immune System With the Risk for Cryptococcus Neoformans Infection in Patients Not Infected With HIV and Complications Associated With Cryptococcus Neoformans Infection

Cryptococcosis

United States
National Cancer Institute (NCI)

Completed

Early Molecular Detection for the Improved Diagnosis of Invasive Pulmonary Aspergillosis and Invasive Pulmonary Zygomycosis

Invasive Pulmonary Aspergillosis | Immunocompromised Host | Invasive Pulmonary Fungal Infection | Invasive Pulmonary Zygomycosis

United States
Arkansas Children's Hospital Research Institute
National Institute of Allergy and Infectious Diseases (NIAID); Children's Hospital...

Recruiting

Non-Invasive Diagnosis of Pediatric Pulmonary Invasive Mold Infections (DOMINIC)

Pulmonary Invasive Fungal Infections | Pulmonary Invasive Aspergillosis

United States, Canada
Astellas Pharma Inc

Withdrawn

A Study to Evaluate the Effectiveness of Voriconazole + Micafungin Versus Voriconazole Alone for Invasive Aspergillosis

Aspergillosis/Blood | Aspergillosis/Invasive

United States
Regeneron Pharmaceuticals
Sanofi

Completed

Investigating Treatment With Dupilumab in Patients With Allergic Bronchopulmonary Aspergillosis (ABPA) (LIBERTY ABPA AIRED)

Allergic Bronchopulmonary Aspergillosis

United States, Hungary, Bulgaria, France, Germany, Japan, Netherlands, Poland, Romania, United Kingdom
University of Pittsburgh
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Open-label Vitamin D Trial for Patients With Cystic Fibrosis and Allergic Bronchopulmonary Aspergillosis

Cystic Fibrosis | Allergic Bronchopulmonary Aspergillosis

United States
University of Pittsburgh
National Heart, Lung, and Blood Institute (NHLBI)

Completed

Mechanisms of Immune Tolerance and Inflammation in Patients With Cystic Fibrosis With ABPA (ABPA)

Cystic Fibrosis | Allergic Bronchopulmonary Aspergillosis

United States
Pulmocide Ltd

Completed

A Study to Investigate the Safety, Tolerability and Pharmacokinetics of Single and Repeat Doses of PC945

Aspergillosis

United Kingdom
F2G Biotech GmbH
Iqvia Pty Ltd; Shionogi

Recruiting

Olorofim Aspergillus Infection Study (OASIS)

Invasive Aspergillosis

United States, Taiwan, Belgium, Spain, Italy, Turkey, New Zealand, China, Canada, Netherlands, Australia, Brazil, Singapore, Israel, France, Thailand, Germany, Japan, Korea, Republic of, United Kingdom
Baylor Research Institute

Withdrawn

Benralizumab in the Treatment of Patients With Severe Asthma With ABPA

Severe Asthma | Allergic Bronchopulmonary Aspergillosis | ABPA

United States
European Organisation for Research and Treatment...

Completed

Comparison of Voriconazole and Amphotericin B in Treating Patients With Aspergillosis

Infection | Pulmonary Complications

France, Spain, Switzerland, Australia, Sweden, Luxembourg, Belgium, Germany, United Kingdom, Hungary, Italy, Israel, Ireland, Netherlands, United States
Pulmocide Ltd

Terminated

The Effect of PC945 on Aspergillus or Candida Lung Infections in Patients With Asthma or Chronic Respiratory Diseases

Bronchiectasis | Asthma | COPD | Respiratory Candidiasis | Respiratory Aspergillosis

United Kingdom
Pulmatrix Inc.

Terminated

Study to Evaluate Itraconazole Administered as Inhaled Dry Powder in Adults With Asthma and ABPA

ABPA

Australia, United States, United Kingdom, France
Pfizer

Terminated

A Study To Evaluate The Safety Of Voriconazole As Treatment Of Invasive Aspergillosis (Fungal Infection) And Other Rare Molds In Children

Invasive Aspergillosis

Spain, United States, Singapore, Canada, Czechia, Netherlands, Poland, Thailand
Pulmocide Ltd

Terminated

The Effect of PC945 on Aspergillus Fumigatus Lung Infection in Patients With Cystic Fibrosis

Cystic Fibrosis | Aspergillosis

United Kingdom
Merck Sharp & Dohme LLC

Completed

Posaconazole (MK-5592) Intravenous and Oral in Children With Invasive Aspergillosis (IA) (MK-5592-104)

Invasive Aspergillosis

Belgium, United States, Greece, Hungary, Israel, Italy, Korea, Republic of, Mexico, Peru, Russian Federation
National Cancer Institute (NCI)

Completed

Voriconazole to Prevent Systemic Fungal Infections in Children

Mycoses | Candidiasis | Aspergillosis | Fungal Diseases

United States
Pulmocide Ltd

Recruiting

Safety and Efficacy of PC945 (Opelconazole) in Combination With Other Antifungal Therapy for the Treatment of Refractory Invasive Pulmonary Aspergillosis (OPERA-T Study)

Refractory IPA

Spain, United States, Canada, Italy, Austria, France, Israel, United Kingdom, Belgium, Korea, Republic of, Brazil, Germany, Chile, Greece, Taiwan, Argentina, Colombia
National Institute of Allergy and Infectious Diseases...

Recruiting

Natural History of Individuals With Immune System Problems That Lead to Fungal Infections

Invasive Aspergillosis | Chronic Mucocutaneous Candidiasis | CARD9 | APECED

United States
Astellas Pharma Global Development, Inc.

Completed

A Study to Evaluate Isavuconazonium Sulfate for the Treatment of Invasive Aspergillosis (IA) or Invasive Mucormycosis (IM) in Pediatric Participants

Invasive Aspergillosis | Invasive Mucormycosis

United States, Belgium, Spain
Astellas Pharma Inc

Completed

Study of FK463 for the Treatment of Invasive Aspergillosis

Aspergillosis

United Kingdom, Austria, France, Germany, Italy, Poland, Spain, Sweden
Scynexis, Inc.

Completed

Study to Evaluate the Safety and Efficacy of the Coadministration of Ibrexafungerp (SCY-078) With Voriconazole in Patients With Invasive Pulmonary Aspergillosis (SCYNERGIA)

Invasive Pulmonary Aspergillosis

United States, Belgium, Canada, Germany, South Africa
Vical

Terminated

VL-2397 Compared to Standard First-Line Treatment for Invasive Aspergillosis (IA) in Adults

Invasive Aspergillosis | Invasive Pulmonary Aspergillosis

United States, Korea, Republic of, Canada, Belgium, France, Germany
National Institute of Allergy and Infectious Diseases...

Recruiting

Cryptococcosis in Previously Healthy Adults

Cryptococcus

United States
University Hospitals, Leicester

Recruiting

Pharmacokinetics of Voriconazole in Adult ECMO Patients

Covid19 | Influenza | Aspergillosis

United Kingdom
St. Bartholomew's Hospital

Unknown

Early Diagnosis of Aspergillosis in Patients at High Risk of Fungal Infection Caused by Treatment for Hematologic Cancer or Other Disease

Myelodysplastic Syndromes | Leukemia | Infection | Graft Versus Host Disease | Myelodysplastic/Myeloproliferative Neoplasms

United Kingdom
Scynexis, Inc.

Completed

Study to Evaluate the Efficacy and Safety of Ibrexafungerp in Patients With Fungal Diseases That Are Refractory to or Intolerant of Standard Antifungal Treatment (FURI)

Coccidioidomycosis | Invasive Pulmonary Aspergillosis | Allergic Bronchopulmonary Aspergillosis | Histoplasmosis | Chronic Pulmonary Aspergillosis | Blastomycosis | Invasive Candidiasis | Recurrent Vulvovaginal Candidiasis | Mucocutaneous Candidiasis | Other Emerging Fungi

United States, Spain, United Kingdom, Austria, Pakistan, South Africa, Germany, Netherlands
University of Alabama at Birmingham
Astellas Pharma Inc; Centers for Disease Control and Prevention

Recruiting

COVID-19 Associated Pulmonary Aspergillosis (CAPA) and Other Invasive Fungal Infections (IFI) (CAPA IFI)

Covid19 | Fungal Infection | Aspergillosis

United States
Jeffrey Jenks, MD, MPH
Astellas Pharma Global Development, Inc.

Terminated

Isavuconazole for the Prevention of COVID-19-associated Pulmonary Aspergillosis (Isavu-CAPA)

Severe Acute Respiratory Syndrome Coronavirus 2 | Aspergillosis Invasive

United States

Clinical Trials on Cryptococcosis or Aspergillosis Infections in United Kingdom

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