Clinical Trials on Cutaneous Squamous Cell Carcinoma in Situ (CSCCis)

Total 12347 results

National Cancer Institute (NCI)

Active, not recruiting

Testing the Addition of an Anti-cancer Drug, BAY 1895344, With Radiation Therapy to the Usual Pembrolizumab Treatment for Recurrent Head and Neck Cancer

Recurrent Head and Neck Squamous Cell Carcinoma | Recurrent Hypopharyngeal Squamous Cell Carcinoma | Recurrent Laryngeal Squamous Cell Carcinoma | Recurrent Oral Cavity Squamous Cell Carcinoma | Recurrent Oropharyngeal Squamous Cell Carcinoma | Clinical Stage III HPV-Mediated (p16-Positive)... and other conditions

United States
Morphogenesis, Inc.

Completed

IFx-Hu2.0 for the Treatment of Patients With Skin Cancer

Basal Cell Carcinoma | Cutaneous Squamous Cell Carcinoma

United States
NRG Oncology
National Cancer Institute (NCI)

Recruiting

Comparing High-Dose Cisplatin Every Three Weeks to Low-Dose Cisplatin Weekly When Combined With Radiation for Patients With Advanced Head and Neck Cancer

Advanced Head and Neck Squamous Cell Carcinoma | Squamous Cell Carcinoma of Unknown Primary | Advanced Hypopharyngeal Squamous Cell Carcinoma | Advanced Laryngeal Squamous Cell Carcinoma | Advanced Oropharyngeal Squamous Cell Carcinoma

United States, Canada
University Hospital, Montpellier
National Cancer Institute, France

Unknown

Circulating Tumor Cells as an Early Predictive head-and -Neck Squamous-cell Carcinoma (CIRCUTEC)

Metastatic Head-and-neck Squamous-cell Carcinoma

France
H. Lee Moffitt Cancer Center and Research Institute
Regeneron Pharmaceuticals; Sanofi-Synthelabo

Recruiting

Neoadjuvant Cemiplimab in Newly Diagnosed or Recurrent Stage I-II Merkel Cell Carcinoma and Locoregionally Advanced Cutaneous Squamous Cell Carcinoma

Merkel Cell Carcinoma | Cutaneous Squamous Cell Carcinoma

United States
Philogen S.p.A.

Recruiting

Intratumoral Administration of Daromun in Non-melanoma Skin Cancer Patients (DUNCAN)

Carcinoma, Basal Cell | Carcinoma, Cutaneous Squamous Cell

Germany, Poland, Switzerland
UNC Lineberger Comprehensive Cancer Center
Mayo Clinic; National Institute of Dental and Craniofacial Research (NIDCR)

Recruiting

Prospective Observational Study to Validate Circulating HPVDNA and Prognostic Genomic Biomarkers in HPV-associated OPSCC

Carcinoma, Squamous Cell | Head and Neck Squamous Cell Carcinoma | Oropharyngeal Squamous Cell Carcinoma | Oropharynx Squamous Cell Carcinoma

United States
Emory University
Synta Pharmaceuticals Corp.

Terminated

Ganetespib Window of Opportunity Study in Head and Neck Cancers

Stage IVA Oral Cavity Squamous Cell Carcinoma | Stage IVA Laryngeal Squamous Cell Carcinoma | Stage IVA Oropharyngeal Squamous Cell Carcinoma | Stage I Hypopharyngeal Squamous Cell Carcinoma | Stage I Laryngeal Squamous Cell Carcinoma | Stage I Oropharyngeal Squamous Cell Carcinoma | Stage II... and other conditions

United States
National Cancer Institute (NCI)

Terminated

Capecitabine and Vorinostat in Treating Patients With Recurrent and/or Metastatic Head and Neck Cancer

Recurrent Hypopharyngeal Squamous Cell Carcinoma | Recurrent Laryngeal Squamous Cell Carcinoma | Recurrent Oral Cavity Squamous Cell Carcinoma | Recurrent Oropharyngeal Squamous Cell Carcinoma | Stage IVA Oral Cavity Squamous Cell Carcinoma | Stage IVA Laryngeal Squamous Cell Carcinoma | Stage... and other conditions

Canada, United States
National Cancer Institute (NCI)

Active, not recruiting

Tacrolimus, Nivolumab, and Ipilimumab in Treating Kidney Transplant Recipients With Selected Unresectable or Metastatic Cancers

Metastatic Melanoma | Unresectable Melanoma | Clinical Stage III Cutaneous Melanoma AJCC v8 | Pathologic Stage IIIB Cutaneous Melanoma AJCC v8 | Pathologic Stage IIIC Cutaneous Melanoma AJCC v8 | Pathologic Stage IIID Cutaneous Melanoma AJCC v8 | Metastatic Merkel Cell Carcinoma | Metastatic Skin... and other conditions

United States
Biotech Pharmaceutical Co., Ltd.

Unknown

Nimotuzumab in Combined With Paclitaxel and Cisplatin for Treatment of Metastatic Esophageal Squamous Cell Carcinoma

Esophageal Squamous Cell Carcinomas

China
Exicure, Inc.

Terminated

Intratumoral Cavrotolimod Combined With Pembrolizumab or Cemiplimab in Patients With Merkel Cell Carcinoma, Cutaneous Squamous Cell Carcinoma, or Other Advanced Solid Tumors

Advanced or Metastatic Solid Tumors | Advanced or Metastatic Merkel Cell Carcinoma | Advanced or Metastatic Cutaneous Squamous Cell Carcinoma | Advanced or Metastatic Melanoma | Advanced or Metastatic Head and Neck Squamous Cell Carcinoma

United States
Sidney Kimmel Cancer Center at Thomas Jefferson...
Bristol-Myers Squibb

Completed

Nivolumab, Carboplatin, and Paclitaxel in Treating Patients With Stage III-IV Head and Neck Squamous Cell Carcinoma That Can Be Removed by Surgery

Stage IVA Oral Cavity Squamous Cell Carcinoma | Stage IV Hypopharyngeal Squamous Cell Carcinoma | Stage IVA Laryngeal Squamous Cell Carcinoma | Stage IVA Oropharyngeal Squamous Cell Carcinoma | Stage IVB Laryngeal Squamous Cell Carcinoma | Stage IVB Oropharyngeal Squamous Cell Carcinoma | Stage... and other conditions

United States
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Recruiting

Neoadjuvant Sintilimab Combined With Reduction of Cycles of Chemotherapy in Resectable Oral Cavity or Oropharyngeal Squamous Cell Carcinoma (OOC-002)

Oropharyngeal Squamous Cell Carcinoma | Oral Squamous Cell Carcinoma | Oral Cavity Squamous Cell Carcinoma

China
Shanghai Chest Hospital

Not yet recruiting

Salvage Immunotherapy and Chemotherapy in Esophageal Squamous Cell Carcinoma Patients Nonresponding to Initial Neoadjuvant Chemoradiotherapy (SINCERE)

Esophageal Squamous Cell Carcinomas
Fuzhou General Hospital

Recruiting

Camrelizumab Combined With Radiotherapy for Adjuvant Treatment of Esophageal Squamous Cell Carcinoma After Surgery

Esophageal Squamous Cell Carcinomas

China
Nanjing Tongren Hospital

Unknown

CTC Detection Rate in SCCHN With a in Vivo Device

Squamous Cell Carcinoma of the Head and Neck | Circulating Tumor Cell

China
National Cancer Institute (NCI)

Completed

Temsirolimus With or Without Cetuximab in Patients With Recurrent and/or Metastatic Head and Neck Cancer Who Did Not Respond to Previous Therapy (MAESTRO HN)

Recurrent Hypopharyngeal Squamous Cell Carcinoma | Recurrent Laryngeal Squamous Cell Carcinoma | Recurrent Oropharyngeal Squamous Cell Carcinoma | Salivary Gland Squamous Cell Carcinoma | Recurrent Lip and Oral Cavity Squamous Cell Carcinoma | Recurrent Nasopharyngeal Keratinizing Squamous... and other conditions

United States, China
Oslo University Hospital

Recruiting

Microbiota Transplant to Cancer Patients Who Have Failed Immunotherapy Using Faeces From Clinical Responders (MITRIC)

Clear Cell Renal Cell Carcinoma | Non-small Cell Lung Cancer | Head and Neck Squamous Cell Carcinoma | Melanoma Stage IV | Cutaneous Squamous Cell Carcinoma | MSI-High

Norway
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Completed

Image-guided Proton Therapy for the Treatment of Locally Advanced Unresectable Head and Neck Cancer

Stage III Cutaneous Squamous Cell Carcinoma of the Head and Neck AJCC v8 | Stage III Hypopharyngeal Carcinoma AJCC v8 | Stage III Laryngeal Cancer AJCC v8 | Stage III Oropharyngeal (p16-Negative) Carcinoma AJCC v8 | Unresectable Head and Neck Squamous Cell Carcinoma | Unresectable Oropharyngeal... and other conditions

United States
University of California, Irvine

Recruiting

De-escalated Radiation for Human Papillomavirus-Positive Squamous Cell Carcinoma of the Oropharynx

HPV Positive Oropharyngeal Squamous Cell Carcinoma

United States
Dana-Farber Cancer Institute

Withdrawn

Stereotactic Boost for Oropharyngeal Squamous Cell Carcinoma

Squamous Cell Carcinoma of the Oropharynx

United States
Peking University Hospital of Stomatology

Recruiting

Neoadjuvant Tislelizumab Plus Chemotherapy for Locally Advanced Oral/Oropharyngeal Cancer (NeoSPOT)

Oropharyngeal Squamous Cell Carcinoma | Oral Squamous Cell Carcinoma

China
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Recruiting

Neoadjuvant Sintilimab in Combination With Carboplatin and Nab-paclitaxel in Resectable Oral Cavity or Oropharyngeal Squamous Cell Carcinoma (OOC-001)

Oropharyngeal Squamous Cell Carcinoma | Oral Squamous Cell Carcinoma

China
University Health Network, Toronto
NuBiyota

Active, not recruiting

Role of Microbiome as a Biomarkers in Locoregionally-Advanced Oropharyngeal Squamous Cell Carcinoma 2 (ROMA LA-OPSCC2)

Head and Neck Squamous Cell Carcinoma

Canada
Washington University School of Medicine

Active, not recruiting

Surgery Followed by Risk-Directed Post-Operative Adjuvant Therapy for HPV-Related Oropharynx Squamous Cell Carcinoma: "The Minimalist Trial (MINT)" (MINT)

HPV Related Oropharyngeal Squamous Cell Carcinoma

United States
Centre hospitalier de l'Université de Montréal...
AstraZeneca

Active, not recruiting

Immunotherapy and SBRT for Metastatic Head and Neck Carcinomas

Head and Neck Squamous Cell Carcinoma | Metastatic Squamous Cell Carcinoma

Canada
University Health Network, Toronto

Completed

Role of Microbiome as a Biomarkers in Locoregionally-Advanced Oropharyngeal Squamous Cell Carcinoma (ROMA LA-OPSCC)

Locoregionally-advanced Oropharyngeal Squamous Cell Carcinoma

Canada
City of Hope Medical Center
National Cancer Institute (NCI)

Completed

Pembrolizumab and Palliative Radiation Therapy in Treating Patients With Metastatic Esophagus, Stomach, or Gastroesophageal Junction Cancer

Gastric Adenocarcinoma | Gastric Squamous Cell Carcinoma | Gastroesophageal Junction Adenocarcinoma | Metastatic Malignant Neoplasm in the Stomach | Stage IV Esophageal Adenocarcinoma AJCC v7 | Stage IV Esophageal Squamous Cell Carcinoma AJCC v7

United States
H. Lee Moffitt Cancer Center and Research Institute
AstraZeneca; Brooklyn ImmunoTherapeutics, LLC

Active, not recruiting

IRX-2 Regimen and Durvalumab, for Incurable H&N Squamous Cell Carcinoma

Squamous Cell Carcinoma of the Head and Neck | Oropharynx Squamous Cell Carcinoma | Squamous Cell Carcinoma | Oral Cavity Squamous Cell Carcinoma | Metastatic Squamous Cell Carcinoma | Hypopharynx Squamous Cell Carcinoma | Paranasal Sinus Squamous Cell Carcinoma | Larynx Squamous Cell Carcinoma

United States
Case Comprehensive Cancer Center
National Cancer Institute (NCI)

Terminated

Stereotactic Body Radiation Therapy in Treating Patients With High Risk Locally Advanced Head and Neck Cancer

Recurrent Hypopharyngeal Squamous Cell Carcinoma | Recurrent Laryngeal Squamous Cell Carcinoma | Recurrent Oral Cavity Squamous Cell Carcinoma | Recurrent Oropharyngeal Squamous Cell Carcinoma | Recurrent Nasopharyngeal Keratinizing Squamous Cell Carcinoma | Stage IVA Oral Cavity Squamous Cell... and other conditions

United States
Sidney Kimmel Cancer Center at Thomas Jefferson...

Completed

Durvalumab With or Without Metformin in Treating Participants With Head and Neck Squamous Cell Carcinoma

Head and Neck Squamous Cell Carcinoma | Oropharyngeal Squamous Cell Carcinoma | Oral Cavity Squamous Cell Carcinoma

United States
Hyunseok Kang, MD
NeoImmuneTech

Recruiting

NT-I7 for the Treatment of Recurrent Squamous Cell Carcinoma of Head and Neck Undergoing Surgery

Recurrent Head and Neck Squamous Cell Carcinoma | Recurrent Hypopharyngeal Squamous Cell Carcinoma | Recurrent Laryngeal Squamous Cell Carcinoma | Recurrent Oral Cavity Squamous Cell Carcinoma | Recurrent Oropharyngeal Squamous Cell Carcinoma | Resectable Oropharyngeal Squamous Cell Carcinoma

United States
Icahn School of Medicine at Mount Sinai

Recruiting

The Sinai Robotic Surgery Trial in HPV-related Oropharyngeal Squamous Cell Carcinoma (SIRS 2.0 Trial)

HPV-positive Oropharyngeal Squamous Cell Carcinoma

United States
Memorial Sloan Kettering Cancer Center

Completed

Molecular Effects of Short-Term Celecoxib Treatment on Head and Neck Squamous Cell Carcinoma

SQUAMOUS CELL CARCINOMA
University Health Network, Toronto
AstraZeneca; Mirati Therapeutics Inc.

Withdrawn

Pre-operative Mocetinostat (MGCD0103) and Durvalumab (MEDI4736) (PRIMED) for Squamous Cell Carcinoma of the Oral Cavity (PRIMED-001)

Squamous Cell Carcinoma, Head And Neck | Squamous Cell Carcinoma Mouth | Resectable Squamous Cell Carcinoma of Oral Cavity

Canada
Onconova Therapeutics, Inc.

Completed

Oral Rigosertib for Squamous Cell Carcinoma

Head and Neck Squamous Cell Carcinoma | Esophageal Squamous Cell Carcinoma | Anal Squamous Cell Carcinoma | Cervical Squamous Cell Carcinoma | Skin Squamous Cell Carcinoma | Lung Squamous Cell Carcinoma | Penile Squamous Cell Carcinoma

United States
Peking University

Unknown

Research of Pathological Imaging Diagnosis of Ocular Tumors Based on New Artificial Intelligence Algorithm

Melanoma (Skin) | Basal Cell Carcinoma | Squamous Cell Carcinoma in Situ | Ocular Tumor | Melanoma in Situ | Nevus Eye | Sebaceous Gland Carcinoma of the Eyelid
Wake Forest University Health Sciences
National Cancer Institute (NCI)

Completed

Prepare to Care, A Supported Self-Management Intervention for Head and Neck Cancer CaregiversHead and Neck Cancer

Recurrent Head and Neck Squamous Cell Carcinoma | Recurrent Hypopharyngeal Squamous Cell Carcinoma | Recurrent Laryngeal Squamous Cell Carcinoma | Caregiver | Salivary Gland Squamous Cell Carcinoma | Malignant Head and Neck Neoplasm | Recurrent Lip and Oral Cavity Squamous Cell Carcinoma | Stage... and other conditions

United States
Nanfang Hospital of Southern Medical University

Recruiting

Efficacy and Safety of Neoadjuvant Pembrolizumab in III-IVA Resectable Oral Squamous Cell Carcinoma (PROBES)

Oral Cavity Squamous Cell Carcinoma

China
UNICANCER

Recruiting

Study Comparing Fibula Free-flap MR With or Without PVP in Patients With OOPC (CURVE)

Oropharynx Squamous Cell Carcinoma | Oral Cavity Squamous Cell Carcinoma

France
Memorial Sloan Kettering Cancer Center

Recruiting

A Dye for the Detection of Cancer of the Tongue and Mouth

Oral Squamous Cell Carcinoma (OSCC)

United States
Katherine L Fedder

Active, not recruiting

Efficacy and Safety of TORS for SCCA

Oropharyngeal Squamous Cell Carcinoma | Supraglottic Squamous Cell Carcinoma

United States
National Taiwan University Hospital

Unknown

Study on the Interplay Between Twist1 and Other EMT Regulators Through microRNA-29 Family.

Head-and-Neck Squamous Cell Carcinoma

Taiwan
Dan Zandberg
Merck Sharp & Dohme LLC; ISA Pharmaceuticals

Recruiting

HPV-16 Vaccination and Pembrolizumab Plus Cisplatin for "Intermediate Risk" HPV-16-associated Head and Neck Squamous Cell Carcinoma

Head and Neck Squamous Cell Carcinoma | HPV-Related Squamous Cell Carcinoma

United States
Instituto do Cancer do Estado de São Paulo
Instituto de Ciências Biomédicas da Universidade de São Paulo

Not yet recruiting

Determination of ALDH1b1 and ALDH2 Polymorphisms Frequency in the Brazilian Population (ALDH2020)

Oral Squamous Cell Carcinoma (OSCC)

Brazil
National Cancer Institute (NCI)

Recruiting

Testing What Happens When an Immunotherapy Drug (Pembrolizumab) is Given by Itself Compared to the Usual Treatment of Chemotherapy With Radiation After Surgery for Recurrent Head and Neck Squamous Cell Carcinoma

Recurrent Head and Neck Squamous Cell Carcinoma | Recurrent Hypopharyngeal Squamous Cell Carcinoma | Recurrent Laryngeal Squamous Cell Carcinoma | Recurrent Oral Cavity Squamous Cell Carcinoma | Recurrent Oropharyngeal Squamous Cell Carcinoma

United States
Roswell Park Cancer Institute

Recruiting

CIMAvax Vaccine, Nivolumab, and Pembrolizumab in Treating Patients With Advanced Non-small Cell Lung Cancer or Squamous Head and Neck Cancer

Metastatic Lung Non-Small Cell Carcinoma | Stage IVA Lung Cancer AJCC v8 | Stage IVB Lung Cancer AJCC v8 | Lung Non-Small Cell Carcinoma | Stage III Lung Cancer AJCC v8 | Stage IV Lung Cancer AJCC v8 | Stage IIIA Lung Cancer AJCC v8 | Stage IIIB Lung Cancer AJCC v8 | Recurrent Head and Neck Squamous... and other conditions

United States
Sichuan Baili Pharmaceutical Co., Ltd.

Recruiting

SI-B001 Combined With Irinotecan in the Treatment of Recurrent Metastatic Esophageal Squamous Cell Carcinoma.

Esophageal Squamous Cell Carcinomas

China
Phio Pharmaceuticals Inc.

Recruiting

Intratumoral PH-762 for Cutaneous Carcinoma

Squamous Cell Carcinoma of the Skin | Malignant Melanoma of Skin | Merkel Cell Carcinoma of Skin

United States

Clinical Trials on Cutaneous Squamous Cell Carcinoma in Situ (CSCCis)

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