Clinical Trials on Cystic Fibrosis (CF) in Netherlands

Total 268 results

AbbVie

Terminated

Study to Evaluate Adverse Events and Change in Disease Activity With Oral Capsules of Galicaftor/Navocaftor/ABBV-119 or Galicaftor/Navocaftor/ABBV-576 Combination Therapies in Adult Participants With Cystic Fibrosis

Cystic Fibrosis (CF)

United States, Australia, Belgium, Hungary, Netherlands, New Zealand, Slovakia, United Kingdom
Horizon Pharma USA, Inc.

Completed

Safety, Tolerability and Efficacy of MP-376 Given for 28 Days to Cystic Fibrosis (CF) Patients

Cystic Fibrosis (CF)

Germany, United States, Netherlands
Maastricht University
Memorial Sloan Kettering Cancer Center; University of Sao Paulo General Hospital and other collaborators

Unknown

The Potential of Radiomics to Differentiate Between Malignant and Benign Bosniak 3 Renal Cysts. (BIII)

Renal Cyst Complex

Netherlands
University Medical Center Groningen
Vertex Pharmaceuticals Incorporated; Marien Hospital Wesel

Completed

Effect of Lumacaftor/Ivacaftor in Children With Cystic Fibrosis Homozygote for F508del on Small Airway Function (ROOTS)

Cystic Fibrosis in Children

Netherlands, Germany
Academisch Medisch Centrum - Universiteit van Amsterdam...

Recruiting

Performance and Patient Acceptance of a Commercially Available Beverage as Compared to an Oral Glucose Solution for Oral Glucose Tolerance Tests in Cystic Fibrosis (CF) Patients Who Are Screened for CF-related Diabetes.

Cystic Fibrosis | Cystic Fibrosis-related Diabetes

Netherlands
University Medical Center Groningen

Recruiting

DPI-Tobra-Kind Cyclops® in Children With Cystic Fibrosis

Cystic Fibrosis

Netherlands
Medical Center Alkmaar

Completed

Inhaled Nebulized Tobramycin in Non-cystic Fibrosis Bronchiectasis (BATTLE)

Non-CF Bronchiectasis

Netherlands
Vertex Pharmaceuticals Incorporated

Completed

Lumacaftor/Ivacaftor Combination Therapy in Subjects With CF Who Have an A455E CFTR Mutation

Cystic Fibrosis

Netherlands
Erasmus Medical Center
Emory University; UMC Utrecht

Completed

Inflammatory Markers in Broncho-alveolar Lavage Fluid as Risk Factors for Lung Disease in Infants With Cystic Fibrosis: the I-BALL Study (I-BALL)

Cystic Fibrosis

Netherlands
Maastricht University Medical Center
AstraZeneca; Cystic Fibrosis Foundation

Completed

Non-Invasive Biomarkers in Cystic Fibrosis

Cystic Fibrosis

Netherlands
Galapagos NV

Completed

Study of GLPG1837 in Subjects With Cystic Fibrosis (S1251N Mutation) (SAPHIRA2)

Cystic Fibrosis

Belgium, Netherlands
University Childrens' Hospital (Zentrum für Kinderheilkunde...
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA); University...

Recruiting

Connexin Genotypes in Cystic Fibrosis

Inflammation | Cystic Fibrosis

Germany, Netherlands
Maastricht University Medical Center

Completed

Breath Analysis in Children by New Point-of-care Instruments

Asthma | Cystic Fibrosis

Netherlands
Vertex Pharmaceuticals Incorporated

Completed

Phase 1, QT/QTC Interval Study in Healthy Subjects

Cystic Fibrosis

Netherlands
Swedish Orphan Biovitrum

Completed

Efficacy of Bucelipase Alfa (BSSL) in Patients With Cystic Fibrosis and Pancreatic Insufficiency

Cystic Fibrosis | Exocrine Pancreatic Insufficiency

Netherlands, Poland
Vertex Pharmaceuticals Incorporated

Completed

Drug-Drug Interaction Study of VX-809 and VX-770 in Healthy Subjects

Cystic Fibrosis

Netherlands
Vertex Pharmaceuticals Incorporated

Completed

Study of VX-121 in Healthy Subjects and in Subjects With Cystic Fibrosis

Cystic Fibrosis

Netherlands, United Kingdom
Maastricht University Medical Center
AstraZeneca; Cystic Fibrosis Foundation

Completed

FLAME: Airway Inflammation Monitoring in Asthma and Cystic Fibrosis

Asthma | Cystic Fibrosis

Netherlands
Maastricht University Medical Center

Unknown

Standardisation of Measurements in Exhaled Breath and Exhaled Breath Condensate.

Pneumonia | Asthma | Cystic Fibrosis | Chronic Lung Disease

Netherlands
Erasmus Medical Center
Stichting TAAI

Active, not recruiting

TAAI Erasmus Research Initiative to Fight CF: Monitoring Inflammation in CF Lung Disease Into a New Era (TERRIFIC-MILE)

Lung Diseases | Cystic Fibrosis | Infections, Bacterial | Congenital Disorders | Lung Inflammation | Lung Infection | Lung Disease; Cystic | Lung Disease; Cystic, Congenital | Inflammation Lungs | Exacerbation, Symptom

Netherlands
Radboud University Medical Center

Completed

Penetration of Cefazolin Into Hepatic Cysts (PENTAC)

Hepatic Cyst

Netherlands
Radboud University Medical Center

Completed

Efficacy of Combining Pasireotide With Aspiration Sclerotherapy to Improve Volume Reduction of Hepatic Cysts (Sclerocyst)

Symptomatic Dominant Liver Cyst

Netherlands
Erasmus Medical Center
Queen's University, Belfast; Cystic Fibrosis Foundation; European Cystic Fibrosis...

Active, not recruiting

COVID-19 Antibody Responses In Cystic Fibrosis (CAR-CF)

Cystic Fibrosis

Netherlands
Maastricht University Medical Center
NCFS; Chiesie Pharmaceuticals B.V.

Completed

Prevention of CF Exacerbation in Childhood: PREVEC Study (PREVEC)

Quality of Life | Children | Cystic Fibrosis | Volatile Organic Compounds | Exhaled Breath Condensate | Home Monitoring | Non-invasive Inflammatory Markers

Netherlands
St. Antonius Hospital
ZonMw: The Netherlands Organisation for Health Research and Development; Boeringer...

Recruiting

Optimising Screening for Early Disease Detection in Familial Pulmonary Fibrosis (FLORIS)

Pulmonary Fibrosis Idiopathic Familial

Netherlands
AstraZeneca

Withdrawn

Study to Assess Efficacy of AZD1236 in Patients With Cystic Fibrosis (CYBER)

Cystic Fibrosis

Netherlands, Poland, Spain, Canada
Vertex Pharmaceuticals Incorporated

Completed

A Study of Lumacaftor in Combination With Ivacaftor in Cystic Fibrosis Subjects Aged 12 Years and Older Who Are Homozygous for the F508del-CFTR Mutation (TRAFFIC)

Cystic Fibrosis, Homozygous for the F508del CFTR Mutation

United States, Germany, Canada, Netherlands, Czech Republic, Italy, Ireland, Sweden, United Kingdom, Australia, France
Insmed Incorporated

Completed

Assessment of INS1007 in Participants With Non-Cystic Fibrosis Bronchiectasis

Non-Cystic Fibrosis Bronchiectasis

United States, Spain, Korea, Republic of, Australia, Denmark, United Kingdom, Italy, Belgium, Singapore, Bulgaria, Germany, Netherlands, New Zealand, Poland
Zambon SpA

Completed

Efficacy and Safety of Inhaled CMS in Bronchiectasis Subjects With Chronic P. Aeruginosa Infection. (PROMIS-I) (PROMIS-I)

Non Cystic Fibrosis Bronchiectasis

Australia, Greece, Israel, Italy, Portugal, Belgium, Germany, Netherlands, New Zealand, Spain, Switzerland, United Kingdom
Bayer
Merck Sharp & Dohme LLC

Terminated

Early Signs of Efficacy Study With Riociguat in Adult Homozygous Delta F508 Cystic Fibrosis Patients

Cystic Fibrosis

Germany, United States, France, Canada, Belgium, Netherlands, United Kingdom
Vertex Pharmaceuticals Incorporated

Completed

Observational Study of Outcomes in Cystic Fibrosis Patients With Selected Gating Mutations on a CFTR Allele (The VOCAL Study) (VOCAL)

Cystic Fibrosis

Netherlands, Italy, United Kingdom
Vertex Pharmaceuticals Incorporated

Completed

A Phase 3 Rollover Study of Lumacaftor in Combination With Ivacaftor in Subjects 12 Years and Older With Cystic Fibrosis

Cystic Fibrosis, Homozygous or Heterozygous for the F508del-CFTR Mutation

United States, France, United Kingdom, Germany, Spain, Belgium, Canada, Australia, Netherlands, Denmark, Czech Republic, Italy, Austria, Ireland, Sweden
Galapagos NV

Completed

A Study Looking at the Safety, Tolerability and Efficacy of the Combination of the Study Drugs GLPG2451 and GLPG2222 With or Without GLPG2737 in Patients With Cystic Fibrosis. (FALCON)

Cystic Fibrosis

Belgium, Bulgaria, Germany, Greece, Netherlands, Serbia, Sweden, United Kingdom
Boehringer Ingelheim

Recruiting

A Study to Test How Well BI 1291583 is Tolerated by People With Cystic Fibrosis Bronchiectasis (Clairafly™)

Bronchiectasis | Cystic Fibrosis

Belgium, Germany, Spain, Netherlands, United States, France, Italy
Insmed Incorporated

Active, not recruiting

A Study to Assess the Efficacy, Safety, and Tolerability of Brensocatib in Participants With Non-Cystic Fibrosis Bronchiectasis (ASPEN)

Non-Cystic Fibrosis Bronchiectasis

New Zealand, United States, Argentina, Australia, Austria, Belgium, Brazil, Bulgaria, Canada, Chile, Colombia, Denmark, France, Germany, Greece, Hungary, Ireland, Israel, Italy, Japan, Korea, Republic of, Latvia, Malaysia, Mexico, Nethe... and more
Academisch Medisch Centrum - Universiteit van Amsterdam...

Recruiting

Dasatinib and Quercetin to Treat Fibrotic Non-alcoholic Fatty Liver Disease

NAFLD | Liver Fibrosis | NASH With Fibrosis

Netherlands
Rijnstate Hospital

Completed

Stellate Ganglion Block to Reduce Hot Flushes

Stellate Ganglion Block | Postmenopausal | Hot Flushes | Hot Flash

Netherlands
Enanta Pharmaceuticals, Inc
PRA Health Sciences

Completed

A Study of EDP-297 in Healthy Subjects

NASH - Nonalcoholic Steatohepatitis With Liver Fibrosis

Netherlands
Echosens

Recruiting

Optimization of Spleen VCTE Examinations With FibroScan

Spleen; Fibrosis

Spain, Netherlands, Romania
Galapagos NV

Completed

A Study to Evaluate Multiple Doses of GLPG2222 in Adult Subjects With Cystic Fibrosis

Cystic Fibrosis

Spain, United Kingdom, United States, Netherlands, Belgium, Serbia
Canisius-Wilhelmina Hospital
Maastricht University Medical Center

Unknown

The Effects of Discontinuation of Vitamin K Antagonists on the Rate of Elastin Degradation

Cystic Fibrosis | Alpha 1-Antitrypsin Deficiency | Aneurysm | Emphysema or COPD

Netherlands
Vertex Pharmaceuticals Incorporated

Completed

A Study Evaluating Efficacy and Safety of Elexacaftor/Tezacaftor/Ivacaftor in Subjects 6 Through 11 Years of Age With Cystic Fibrosis and F/MF Genotypes

Cystic Fibrosis

Canada, France, Germany, United Kingdom, Israel, Australia, Spain, Netherlands, Denmark, Switzerland
University of Washington, the Collaborative Health...
Cystic Fibrosis Foundation

Completed

Saline Hypertonic in Preschoolers + CT (SHIP-CT)

Cystic Fibrosis

Spain, United States, Australia, Italy, France, Canada, Belgium, Denmark, Netherlands
Erasmus Medical Center
St. Antonius Hospital; OLVG; Zuyderland Medical Centre

Completed

Home Monitoring in Idiopathic Pulmonary Fibrosis; Improving Use of Anti-fibrotic Medication and Quality of Life

Idiopathic Pulmonary Fibrosis

Netherlands
Vertex Pharmaceuticals Incorporated

Completed

A Study Evaluating the Long-term Safety and Efficacy of Elexacaftor/Tezacaftor/Ivacaftor in Cystic Fibrosis (CF) Particpants 6 Years and Older and F/MF Genotypes

Cystic Fibrosis

Canada, France, United Kingdom, Israel, Australia, Spain, Germany, Netherlands, Denmark, Switzerland
Maastricht University
Université Libre de Bruxelles

Completed

To Evaluate the Use of Radiomics to Classify Between Idiopathic Pulmonary Fibrosis and Interstitial Lung Disease

Idiopathic Pulmonary Fibrosis | Interstitial Lung Disease | Usual Interstitial Pneumonia

Netherlands
UMC Utrecht

Terminated

Targeted Vessel Ablation of Type 3 Uterine Fibroids With Magnetic Resonance Guided High Intensity Focused Ultrasound

Uterine Fibroid

Netherlands
Vertex Pharmaceuticals Incorporated

Completed

A Study to Evaluate the Safety and Efficacy of VX-121 Combination Therapy in Subjects With Cystic Fibrosis

Cystic Fibrosis

United States, Netherlands, United Kingdom, Germany, Portugal
Vertex Pharmaceuticals Incorporated

Completed

Study of VX-809 in Cystic Fibrosis Subjects With the ∆F508-CFTR Gene Mutation

Cystic Fibrosis

United States, Belgium, Canada, Netherlands, Germany
Leiden University Medical Center
Amgen

Recruiting

Denosumab in Subjects With Giant Cell Rich Tumors of Bone

Aneurysmal Bone Cysts | Giant Cell Granuloma | Osteoblastoma | Chondroblastoma | Chondromyxoid Fibroma

France, Italy, Netherlands

Clinical Trials on Cystic Fibrosis (CF) in Netherlands

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