Clinical Trials on Cytopenia

Total 195 results

Maastricht University Medical Center

Completed

Low Bacterial Diet in Patients With Cytopenia

Cytopenia

Netherlands
National Institute of Allergy and Infectious Diseases...

Recruiting

A Phase I Study of Mozobil in the Treatment of Patients With WHIMS

Infections | Warts | Neutropenia | Leukopenia | Myelokathexis

United States
Novartis Pharmaceuticals

Completed

A Study to Assess the Safety and Efficacy of Eltrombopag in Japanese Subjects With Refractory, Moderate or More Severe Aplastic Anemia

Cytopaenia

Japan
Hanny Al-Samkari, MD
Swedish Orphan Biovitrum

Recruiting

Avatrombopag vs. Placebo for CIT in GI Malignancies (ACT-GI)

Gastrointestinal Neoplasms | Gastrointestinal Cancer | Chemotherapy-Induced Thrombocytopenia

United States
Basilea Pharmaceutica
The Clinical Trials Centre Cologne

Completed

Safety and Pharmacokinetics of Intravenous and Oral APX001 in Patients With Acute Myeloid Leukemia (AML) and Neutropenia

Acute Myeloid Leukemia

Germany
Johns Hopkins Bloomberg School of Public Health
Johns Hopkins University; University of Maryland; University of California, San... and other collaborators

Recruiting

Platelet-Directed Whole Blood Transfusion Strategy for Malaria (PLATFORM)

Thrombocytopenia | Severe Malaria

United States, Zambia
Kirsten Grønbæk
Zealand University Hospital; University of Copenhagen; Herlev Hospital; Steno Diabetes... and other collaborators

Recruiting

Repurposing Metformin as a Leukemia-preventive Drug in CCUS and LR-MDS

Preleukemia | Cytopenia | Myelodysplastic Neoplasm | Preleukemic Anemia

Denmark
Boston Children's Hospital
National Heart, Lung, and Blood Institute (NHLBI); Beth Israel Deaconess Medical...

Recruiting

Impact of Thrombocytopenia and Platelet Transfusions on Neonatal Bleeding and Inflammation

Neonatal Thrombocytopenia

United States
National Institute of Allergy and Infectious Diseases...

Recruiting

Hematopoietic Stem Cell Mobilization in Idiopathic CD4 Lymphocytopenia Patients and Healthy Controls for the Study of T Cell Maturation and Trafficking in Murine Models

Idiopathic CD4-Positive | T-Lymphocytopenia

United States
Sandoz

Completed

A Phase I/II Study of Recombinant Human GM-CSF in Patients With AIDS Virus Infection and Leukopenia

HIV Infections | Cytopenias

United States
Sandoz

Completed

An Open Label Phase I Study of Subcutaneously Administered Recombinant Human GM-CSF in Patients With AIDS Virus Infection and Leukopenia

HIV Infections | Cytopenias

United States
Sandoz

Completed

A Pilot Study to Evaluate the Effects of Subcutaneously Administered Recombinant Human Granulocyte-Macrophage Colony Stimulating Factor in Pediatric HIV-Infected Patients With Neutropenia Secondary to Azidothymidine

HIV Infections | Cytopenias

United States
Henry Ford Health System

Completed

Response to SARS-CoV-2 Vaccine in Stem Cell Transplant and Cellular Therapy Patients

Hematologic Disorders and Bone Marrow Failure, Hematopoietic Stem Cell Transplantation (HSCT) or Cellular Therapy (CART)

United States
Rallybio IPA, LLC

Recruiting

Study to Assess the Occurrence of HPA-1a Alloimmunization in Women With Higher Risk for Fetal and Neonatal Alloimmune Thrombocytopenia

Fetal and Neonatal Alloimmune Thrombocytopenia

United States, Canada, Netherlands, Norway, United Kingdom, Sweden, Germany
M.D. Anderson Cancer Center
National Cancer Institute (NCI)

Recruiting

Major Complication Rate in Cancer Patients With Neutropenic Fever Potentially Eligible for a Hospital at Home Program

Hematopoietic and Lymphoid Cell Neoplasm | Malignant Solid Neoplasm

United States
Centre Hospitalier Universitaire Vaudois
Unisanté Centre universitaire de médecine générale et santé publique; FORCE...

Not yet recruiting

Adjustment of Antibiotic Dosage in Pediatric Oncology Patients With Febrile Neutropenia and Augmented Renal Clearance (DAR-ARC)

Febrile Neutropenia

Switzerland
Institute of Hematology & Blood Diseases Hospital...

Recruiting

Pegylated Interferon Alfa-2b Versus Interferon Alfa Therapy in Childhood and Adolescent Essential Thrombocythemia

Essential Thrombocytopenia

China
Amgen

Completed

Determination of Safe Dose of Romiplostim (AMG 531) in Patients With Myelodysplastic Syndromes (MDS)

Myelodysplastic Syndromes | Thrombocytopenia | MDS | Refractory Cytopenias
Tufts Medical Center

Recruiting

Letermovir for Secondary Prophylaxis in Solid Organ Transplant Recipients

Neutropenia | Cytomegalovirus Infections | Infection in Solid Organ Transplant Recipients | Antiviral Toxicity

United States
Beneficência Portuguesa de São Paulo
Merck Sharp & Dohme LLC

Not yet recruiting

Ceftolozane/Tazobactam Versus Meropenem for Febrile Neutropenia on Patients Colonized With or at Risk for Infection With Extended Spectrum Beta Lactamase - Producing Pathogens (CLEMENT)

Febrile Neutropenia

Brazil
Mayo Clinic

Recruiting

Pre-myeloid Cancer and Bone Marrow Failure Clinic Study

Hematologic Neoplasms | Myeloid Malignancy | Cytopenia | Bone Marrow Failure Syndrome | Clonal Cytopenia of Undetermined Significance | Clonal Hematopoiesis of Indeterminate Potential | Low Risk Myelodysplastic Syndrome | Inherited Bone Marrow Failure Syndrome | Clonal Expansion | Hereditary Neoplastic... and other conditions

United States
Murdoch Childrens Research Institute

Recruiting

Early Versus Late Stopping of Antibiotics in Children With Cancer and High-risk Febrile Neutropenia (ELSA-FN)

Febrile Neutropenia

Australia
Lawson Health Research Institute

Recruiting

A Prospective Study on the Long-Term Vascular Burden in Thrombotic Thrombocytopenic Purpura Patients (TTP)

Thrombotic Thrombocytopenic Purpura

Canada
Wake Forest University Health Sciences

Recruiting

Antimicrobial Revision in Persistent Febrile Neutropenia

Febrile Neutropenia

United States
Meyer Children's Hospital IRCCS

Active, not recruiting

Autoimmune Cytopenias as a Sign of Primary Immunodeficiency.

Cytopenia

Italy, United States, Belgium
Fujian Medical University Union Hospital
The Affiliated Hospital Of Guizhou Medical University; The Second Hospital... and other collaborators

Recruiting

Short-course High-dose Prednisone and Dexamethasone in Children With ITP

Immune Thrombocytopenia | Child, Only | Glucocorticoids

China
Pfizer

Recruiting

Safety and Efficacy Study of PF-06835375 in Primary Immune Thrombocytopenia

Primary Immune Thrombocytopenia

United States, Australia, Canada, Czechia, Poland, Hungary, United Kingdom
Kyowa Kirin China Pharmaceutical Co., Ltd.

Completed

Evaluating the Pharmacokinetics and Pharmacodynamics of Romiplostim in Patients With Immune Thrombocytopenia (ITP)

Immune Thrombocytopenia (ITP)

China
Anjali Sharathkumar
Amgen

Active, not recruiting

TPO-Mimetic Use in Children for Hematopoietic Failure

Thrombocytopenia | Bone Marrow Failure Disorders | Aplastic Anemia | Refractory Cytopenia of Childhood | Myelodysplastic Syndrome(MDS)

United States
Universitaire Ziekenhuizen KU Leuven
University Hospital, Ghent; Universitair Ziekenhuis Brussel; University Hospital... and other collaborators

Recruiting

Stopping Antibiotics After 3 Days for the Treatment of High-risk FEbrile Neutropenia (SAFE)

Neutropenia, Febrile

Belgium
Tufts Medical Center
Merck Sharp & Dohme LLC

Active, not recruiting

Letermovir Use in Heart Transplant Recipients

Neutropenia | Cytomegalovirus Infections | Cytomegalovirus Disease | Heart Transplant Infection | Antiviral Toxicity

United States
Changzhou No.2 People's Hospital
Rui Therapeutics Co., Ltd

Not yet recruiting

An Clinical Study of CD19 CAR NK Cells for the Treatment of Refractory Primary Immune Thrombocytopenia

Thrombocytopenia Alloimmune
University of Cologne

Recruiting

Retrospective Analysis of the Efficiency of Caplacizumab in the Treatment of aTTP (REACT-2020)

Acquired Thrombotic Thrombocytopenic Purpura

Germany
Fred Hutchinson Cancer Center
National Cancer Institute (NCI)

Terminated

Iodine I 131 Monoclonal Antibody BC8, Fludarabine Phosphate, Cyclophosphamide, Total-Body Irradiation and Donor Bone Marrow Transplant in Treating Patients With Advanced Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia, or High-Risk Myelodysplastic Syndrome

Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome | Chronic Myelomonocytic Leukemia | Previously Treated Myelodysplastic Syndrome | Adult Acute Myeloid Leukemia in Remission | Adult Acute Lymphoblastic Leukemia in Remission | Refractory Anemia With Excess Blasts | Refractory... and other conditions

United States
Instituto Nacional de Cancerologia de Mexico

Recruiting

Ceftolozane/Tazobactam vs. Piperacillin/Tazobactam for the Treatment of Bacteremia in Hemato-oncological Patients

Hematologic Neoplasms | Neutropenia

Mexico
Fundación Española de Hematología y Hemoterapía

Recruiting

Spanish-Portuguese Thrombotic Thrombocytopenic Purpura Registry (RE-PTT)

Purpura, Thrombocytopenic

Spain
Rigshospitalet, Denmark
Odense University Hospital; University of Copenhagen; Imperial College London; University... and other collaborators

Active, not recruiting

Epigenetics, Vitamin C, and Abnormal Blood Cell Formation - Vitamin C in Patients With Low-Risk Myeloid Malignancies (EVITA)

Myelodysplastic Syndromes | Cytopenia | Chronic Myelomonocytic Leukemia-1

Denmark, United States
Kyowa Kirin Korea Co., Ltd.

Completed

An Observational Study to Evaluate the Safety and Efficacy of Pegfilgrastim (Neulasta®)

Breast Neoplasm Female | Breast Cancer Female

Korea, Republic of
Boehringer Ingelheim

Terminated

Multiple Rising Does Study (Subcutaneous Doses) of BI 655064 in Male and Female Patients With Chronic Primary Immune Thrombocytopenic Purpura (ITP).

Purpura, Thrombocytopenic, Idiopathic

United States
University of Colorado, Denver
National Heart, Lung, and Blood Institute (NHLBI)

Not yet recruiting

Optimizing Pulsatility During Cardiopulmonary Bypass to Reduce Acute Kidney Injury

Thrombocytopenia | Surgery | Acute Kidney Injury | Hemolysis

United States
AO GENERIUM

Completed

Comparative Study of Clinical Efficacy and Safety of GNR-069 and Nplate in Patients With ITP

Idiopathic Thrombocytopenic Purpura

Russian Federation
Gruppo Italiano Malattie EMatologiche dell'Adulto

Recruiting

Biologic Characterization of Patients With ITP

Immune Thrombocytopenia

Italy
Sanofi

Recruiting

Caplacizumab and Immunosuppressive Therapy Without Firstline Therapeutic Plasma Exchange in Adults With Immune-mediated Thrombotic Thrombocytopenic Purpura (MAYARI)

Thrombotic Thrombocytopenic Purpura

Italy, Belgium, France, Greece, United States, Austria, Canada, Czechia, Germany, Japan, Netherlands, Spain, United Kingdom
Baylor College of Medicine
Boston Children's Hospital; University of California, San Francisco

Active, not recruiting

Eltrombopag vs Standard Front Line Management for Newly Diagnosed Immune Thrombocytopenia (ITP) in Children

Immune Thrombocytopenia

United States
Rigel Pharmaceuticals

Terminated

Observational Study of Fostamatinib as Second Line Therapy in Adult Patients With Immune Thrombocytopenia (ITP) and Insufficient Response to a Prior Therapy

Immune Thrombocytopenia | ITP

United States
Boston Children's Hospital
Baylor College of Medicine; Children's Hospital of Philadelphia; Columbia University and other collaborators

Completed

Association of Platelet Parameters With Bleeding Severity in Children With ITP (ITP-APPS)

Immune Thrombocytopenia

United States
Principia Biopharma, a Sanofi Company

Recruiting

Study to Evaluate Rilzabrutinib in Adults and Adolescents With Persistent or Chronic Immune Thrombocytopenia (ITP) (LUNA 3)

Immune Thrombocytopenia

United States, China, Argentina, Australia, Brazil, Canada, France, Hungary, Israel, Korea, Republic of, Mexico, Russian Federation, Singapore, Spain, Thailand, United Kingdom, Austria, Chile, Germany, Italy, Japan, Netherlands, Norway and more
Kyowa Kirin China Pharmaceutical Co., Ltd.

Completed

Efficacy and Safety of Romiplostim in Adult Subjects With Persistent or Chronic Immune Thrombocytopenia (ITP)

Immune Thrombocytopenia

China
920th Hospital of Joint Logistics Support Force...

Recruiting

Efficacy and Safety of CAR-T Cells Therepy for Chronic or Refractory Primary Immune Thrombocytopenia (ITP)

ITP - Immune Thrombocytopenia

China
University Hospital, Rouen

Not yet recruiting

Efficacy and Safety of Immunosuppression, Caplacizumab and Plasma Infusion Without Therapeutic Plasma Exchange in Immune-mediated Thrombotic Thrombocytopenic Purpura: Multicentric Non-inferiority Single-arm Study (PEX-FREE)

Thrombotic Microangiopathies

Clinical Trials on Cytopenia

Sponsors and Collaborators

Medical Conditions

Drug Interventions

CROs by country

CROs in Moldova

Conditions

Rare Diseases

Drug Interventions

Dietary Supplements

Sponsor/Collaborators

Locations