Clinical Trials on DNA Repair-Deficiency Disorders
Total 10252 results
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IRCCS San RaffaeleFondazione TelethonCompletedSevere Combined Immunodeficiency Syndrome
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Yang LiRuijin HospitalRecruitingPediatric Cancer | Li-Fraumeni Syndrome | p53 MutationsChina
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The Hospital for Sick ChildrenEnrolling by invitation
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Institute of Cancer Research, United KingdomCancer Research UK; National Institute for Health Research, United KingdomCompletedLi-Fraumeni SyndromeUnited Kingdom
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National Cancer Institute (NCI)CompletedLi-Fraumeni SyndromeUnited States
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Neena Kapoor, M.D.Terminated
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University of California, San FranciscoWithdrawnSevere Combined Immunodeficiency | Stem Cell Transplant | Transplacental Maternal EngraftmentUnited States
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University of WashingtonActive, not recruitingBRCA1 Gene Mutation | BRCA2 Gene Mutation | Castration-Resistant Prostate Carcinoma | Homologous Recombination Deficiency | PSA Progression | Stage IV Prostate Adenocarcinoma AJCC v7 | Castration Levels of Testosterone | ATM Gene Mutation | Prostate Carcinoma Metastatic in the Bone | PSA Level Greater...United States
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National Cancer Institute (NCI)RecruitingNeoplasms | Li-Fraumeni Syndrome | Tp53 MutationsUnited States
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University of MinnesotaRecruitingDNA Repair Disorder | Xeroderma Pigmentosum | Cockayne Syndrome | TrichothiodystrophyUnited States
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National Institute of Allergy and Infectious Diseases...National Center for Advancing Translational Sciences (NCATS); Primary Immune...Enrolling by invitationADA-SCID | Omenn Syndrome | SCID | Reticular Dysgenesis | XSCID | Leaky SCIDUnited States, Canada
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University of California, San FranciscoCompletedSevere Combined Immunodeficiency | T Cell LymphocytopeniaUnited States
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Gustave Roussy, Cancer Campus, Grand ParisCompleted
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Abramson Cancer Center of the University of PennsylvaniaChildren's Hospital of PhiladelphiaRecruiting
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National Heart, Lung, and Blood Institute (NHLBI)CompletedMitochondrial Disorders | Li-Fraumeni Syndrome | Carriers of p53 MutationUnited States
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Dana-Farber Cancer InstituteActive, not recruiting
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Istituto Ortopedico RizzoliRecruitingLi-Fraumeni Syndrome | Li-Fraumeni-Like SyndromeItaly
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PRG Science & Technology Co., Ltd.Amarex Clinical ResearchCompletedHutchinson-Gilford Progeria Syndrome | Werner SyndromeUnited States
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National Human Genome Research Institute (NHGRI)Withdrawn
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David WilliamsActive, not recruitingGene Therapy | Severe Combined Immunodeficiency, X LinkedUnited States, United Kingdom
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National Institute of Allergy and Infectious Diseases...UnknownX-Linked Combined Immunodeficiency DiseasesUnited States
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National Institute of Allergy and Infectious Diseases...CompletedSevere Combined ImmunodeficiencyUnited States
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Great Ormond Street Hospital for Children NHS Foundation...RecruitingSevere Combined Immunodeficiency, X-LinkedUnited Kingdom
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National Institute of Allergy and Infectious Diseases...National Center for Advancing Translational Sciences (NCATS); Office of Rare... and other collaboratorsEnrolling by invitationOmenn Syndrome | Reticular Dysgenesis | Severe Combined Immunodeficiency (SCID) | XSCID | Leaky SCID | ADA SCIDUnited States, Canada
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Shenzhen Geno-Immune Medical InstituteUnknownAdenosine DeAminase Severe Combined ImmunoDeficiency (ADA-SCID)China
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Fred Hutchinson Cancer CenterNational Cancer Institute (NCI); National Heart, Lung, and Blood Institute...CompletedSevere Combined Immunodeficiency | Adenosine Deaminase Deficiency | Immune System Disorder | Autosomal Recessive Disorder | Purine-Nucleoside Phosphorylase Deficiency | Severe Combined Immunodeficiency With Absence of T and B Cells | X-Linked Severe Combined ImmunodeficiencyUnited States
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Children's Hospital of Chongqing Medical UniversityRecruiting
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Assistance Publique - Hôpitaux de ParisNot yet recruiting
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Assistance Publique - Hôpitaux de ParisRecruitingPediatric Patients | Any Type of Severe Combined Immunodeficiency (SCID) | Partial HLA Incompatible Allogeneic Hematopoietic Stem Cell Transplantation (HSCT)France
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Great Ormond Street Hospital for Children NHS Foundation...UnknownX-linked Severe Combined ImmunodeficiencyUnited Kingdom
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Direction Centrale du Service de Santé des ArméesUnknownKaposi's DiseaseFrance
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Dana-Farber Cancer InstituteNational Cancer Institute (NCI); Baylor College of Medicine; City of Hope Medical...RecruitingTP53 Gene Mutation | Li-Fraumeni Syndrome | Hereditary Cancer Syndrome | Mosaicism | Clonal HematopoiesisUnited States
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Clinuvel Europe LimitedRecruitingXeroderma PigmentosumBelgium, Spain
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The Affiliated Nanjing Drum Tower Hospital of Nanjing...RecruitingChemotherapy Effect | DNA Damage Repair Deficiency | Chemotherapeutic Toxicity | Hormone Sensitive Metastatic Prostate CancerChina
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WellSpan HealthActive, not recruitingEndometrial Hyperplasia | Lynch Syndrome | Endometrial Cancer | Microsatellite Instability | Mismatch Repair DeficiencyUnited States
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Guy's and St Thomas' NHS Foundation TrustKing's College London; Newcastle University; University of CambridgeCompletedXeroderma PigmentosumUnited Kingdom
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Grifols Therapeutics LLCCompletedCommon Variable Immunodeficiency | Severe Combined Immunodeficiency | Wiskott-Aldrich Syndrome | Agammaglobulinemia | Immunologic Deficiency SyndromeCanada, United States
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Scripps HealthJ. Craig Venter InstituteCompletedLi-Fraumeni Syndrome | Hereditary Cancer Syndromes | TP53 Gene Germline Mutation CarrierUnited States
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Clinuvel Europe LimitedRecruitingXeroderma PigmentosumGermany
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National Institute of Allergy and Infectious Diseases...RecruitingX-linked Severe Combined Immunodeficiency (XSCID)United States
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St. Jude Children's Research HospitalNational Heart, Lung, and Blood Institute (NHLBI); Assisi Foundation; California...SuspendedSevere Combined Immunodeficiency Disease, X-linkedUnited States
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Assistance Publique - Hôpitaux de ParisCompletedX-linked Severe Combined ImmunodeficiencyFrance
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Henry Ford Health SystemUnknown
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National Heart, Lung, and Blood Institute (NHLBI)CompletedCancer | Muscle Weakness | Skin FibroblastsUnited States
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Baylor College of MedicineNational Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) and other collaboratorsCompletedRothmund-Thomson SyndromeUnited States
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Applied GeneticsUnknownPrecancerous ConditionUnited States, Germany, United Kingdom
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Yu jirenRecruitingAdenocarcinoma of the Stomach | Mismatch Repair Deficiency | Adenocarcinoma of Esophagogastric JunctionChina
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National Institute of Allergy and Infectious Diseases...RecruitingChronic Granulomatous Disease (CGD) | X-Linked Severe Combined Immune Deficiency (XSCID) | Leukocyte Adhesion Deficiency 1 (LAD) | Graft Versus Host Disease (cGvHD)United States
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M.D. Anderson Cancer CenterNational Cancer Institute (NCI)CompletedHigh-Frequency Microsatellite Instability | Mismatch Repair Gene Mutation | Mutation-Negative Lynch Syndrome | Mutation-Positive Lynch SyndromeUnited States
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University Hospital, Strasbourg, FranceRecruiting