Clinical Trials on DYT 1

Total 5729 results

Indiana University

Completed

Phase II Study of Gleevec/Imatinib Mesylate (STI-571, NCS 716051) in Neurofibromatosis (NF1) Patients With Plexiform Neurofibromas

Neurofibromatosis

United States
Hospices Civils de Lyon

Recruiting

Retrospective and Prospective Follow-up of Patients With Primary Hyperoxaluria Type 1 Treated With Lumasiran in France. (DAILY-LUMA)

Patients With PH1 Treated With Lumasiran in France

France
Johns Hopkins University
Neurofibromatosis Therapeutic Acceleration Program

Recruiting

Mirdametinib Monotherapy in Adults With Neurofibromatosis 1 (NF1) and Cutaneous Neurofibromas (cNF). (Mirda)

Cutaneous Neurofibroma | NF1 | Monotherapy

United States
Medical University of Lodz
Medical University of Silesia; Medical University of Gdansk; Institute of Medical... and other collaborators

Not yet recruiting

Lisdexamphetamine vs Methylphenidate for Pediatric Patients With ADHD and Type 1 Diabetes (LAMAinDiab)

Diabetes Mellitus, Type 1 | Attention Deficit Disorder With Hyperactivity
University of Stavanger
Stavanger Municipality, Norway

Recruiting

Health Determinants in Older Adults Living at Home

Frailty | Healthy Aging | Alcohol Use, Unspecified | Mental Health Issue | Social Functioning | Vision and Hearing Loss | Cognitive Function, Social 1

Norway
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.

Not yet recruiting

A Clinical Trial to Evaluate the Tolerability and Pharmacokinetics of TQ-B3234 in Patients With Type I Neurofibromatosis

Type I Neurofibromatosis

China
National Cancer Institute (NCI)

Recruiting

Prospective Evaluation of High Resolution Dual Energy Computed Tomographic Imaging, Noninvasive (Liquid) Biopsies, and Minimally Invasive Surgical Surveillance for Early Detection of Mesotheliomas in Patients With BAP1 Tumor Predisposition Syndrome

Mesothelioma | Familial Cancer | BRCA1-Associated Protein-1 (BAP1) Mutations | Tumor Predisposition Syndrome (TPDS)

United States
Massachusetts General Hospital
United States Department of Defense

Recruiting

Resiliency Training in Adolescents With NF1 and NF2

Neurofibromatoses

United States
VA Eastern Colorado Health Care System

Recruiting

Impact of HIV-1 and Aging on Mucosal Vaccine Responses

HIV Infections | HIV/AIDS | Human Immunodeficiency Virus | HIV-1-infection

United States
Sclnow Biotechnology Co., Ltd.

Not yet recruiting

Umbilical Cord Mesenchymal Stem Cells Therapy (19#iSCLife®-SA) for Patients With Spinocerebellar Ataxia

Spinocerebellar Ataxia Type 3 | Spinocerebellar Ataxia Type 1 | Spinocerebellar Ataxia Type 2 | Spinocerebellar Ataxia Type 6
University of California, Los Angeles

Active, not recruiting

Open Pilot Trial of BHV-4157

Spinocerebellar Ataxias | Spinocerebellar Ataxia 3 | Spinocerebellar Ataxia Type 1 | Spinocerebellar Ataxia Type 2 | Spinocerebellar Ataxia Type 6 | MSA-C

United States
Nationwide Children's Hospital

Suspended

Phase I/IIa Trial of scAAV1.tMCK.NTF3 for Treatment of CMT1A

Charcot-Marie-Tooth Neuropathy Type 1A

United States
Region Skane
Novartis

Active, not recruiting

Treatment of NF1-related Plexiform Neurofibroma With Trametinib (plexifpc)

Child | Neurofibromatosis 1 | Neurofibroma, Plexiform

Sweden
Cellatoz Therapeutics, Inc

Active, not recruiting

The Safety and Tolerability of CLZ-2002 in Patients With Charcot-Marie Tooth Disease.

Charcot Marie Tooth Disease, Type 1

Korea, Republic of
National Cancer Institute (NCI)

Completed

Systematically Assessing Changes in Plexiform Neurofibroma Related Disfigurement From Photographs of Subjects With Neurofibromatosis Type 1 on a Phase 2 Clinical Trial

Neurofibromatosis 1

United States
Novartis Gene Therapies

Active, not recruiting

Long-Term Follow-up Study for Patients From AVXS-101-CL-101 (START)

Spinal Muscular Atrophy 1

United States
Virginia Commonwealth University

Completed

Intervention Effectiveness on the Neurocognitive Functioning of Children and Adolescents With Neurofibromatosis Type 1 (OPTIMAL-SSI)

Neurofibromatosis 1 | Neurocognitive Deficit | Mental Health Impairment

United States
University of Wisconsin, Milwaukee
NF Midwest

Active, not recruiting

Open Trial of Telehealth Group for Improving Peer Relationships (PEERS) in NF1

Social Skills | Neurofibromatosis 1

United States
Prof. Dr. Fridoon Jawad Ahmad
University of Lahore; Bahria International Hospital

Unknown

To Determine the Efficacy of Neurokinin 1 Receptor Antagonist as a Therapeutic Tool Against Cytokine Storm and Respiratory Failure in Covid-19 Patients

Neurokinin 1 Receptor, Substance P, Respiratory Illness, Inflammation, Covid-19, Coronavirus

Pakistan
National Cancer Institute (NCI)

Completed

Pirfenidone in Children and Young Adults With Neurofibromatosis Type I and Progressive Plexiform Neurofibromas

Neurofibromatosis 1 | Neurofibroma, Plexiform

United States
Assistance Publique - Hôpitaux de Paris
Association Française contre les Myopathies (AFM), Paris

Unknown

Efficacy and Tolerance of Early Launching of Nocturnal Non Invasive (DYVINE)

Respiratory Insufficiency | Myopathy | Muscular Weakness

France
Assistance Publique - Hôpitaux de Paris

Completed

Primary Pigmented Nodular Adrenocortical Disease (PPNAD) and the CARNEY Complex (CNC) (EVACARNEY)

Primary; Complex | Pigmented Nodular Adrenocortical Disease, Primary, 1 | Periorificial Lentiginosis | Cardiac Myxoma

France
National Cancer Institute (NCI)

Terminated

Fenretinide and Rituximab in Treating Patients With B-Cell Non-Hodgkin Lymphoma

Nodal Marginal Zone B-cell Lymphoma | Recurrent Adult Burkitt Lymphoma | Recurrent Adult Diffuse Large Cell Lymphoma | Recurrent Adult Lymphoblastic Lymphoma | Recurrent Grade 1 Follicular Lymphoma | Recurrent Grade 2 Follicular Lymphoma | Recurrent Mantle Cell Lymphoma | Recurrent Marginal Zone... and other conditions

United States
Children's Hospital Medical Center, Cincinnati

Recruiting

RASopathy Biorepository

Neurofibromatosis 1 | Noonan Syndrome | Legius Syndrome | Cardiofaciocutaneous Syndrome | Costello Syndrome | SYNGAP1-Related Intellectual Disability | DLG4 | RAS Mutation | Noonan Syndrome With Multiple Lentigines | Noonan Neurofibromatosis Syndrome | Smith-Kingsmore Syndrome | MTOR Gene Mutation | GATOR-1 Gene... and other conditions

United States
Cairo University

Not yet recruiting

Association Between Molar Incisor Hypomineralization And Type I Diabetes Milletus. (MIH and TIDM)

Molar Incisor Hypomineralization
Massachusetts General Hospital
Patient-Centered Outcomes Research Institute

Not yet recruiting

A Decentralized Clinical Trial to Promote Evidence-Based Care for Underserved Patients With Neurofibromatosis 1

Neurofibromatosis 1

United States
University of Rochester
National Institute of Neurological Disorders and Stroke (NINDS)

Recruiting

Myotonic Dystrophy and Facioscapulohumeral Muscular Dystrophy Registry

Muscular Dystrophy | Myotonic Dystrophy Type 2 | Myotonic Dystrophy Type 1 | Myotonic Dystrophy | Facioscapulohumeral Muscular Dystrophy | Steinert's Disease | Congenital Myotonic Dystrophy | PROMM (Proximal Myotonic Myopathy) | Myotonic Muscular Dystrophy

United States
Teachers College, Columbia University

Active, not recruiting

Priming Motor Learning Through Exercise in People With Spinocerebellar Ataxia (PRIME-Ataxia)

Spinocerebellar Ataxia Type 3 | Spinocerebellar Ataxia Type 1 | Spinocerebellar Ataxia Type 2 | Spinocerebellar Ataxia Type 6 | Spinocerebellar Ataxia Type 7

United States
Robert Lowsky
National Cancer Institute (NCI); Janssen, LP; The Leukemia and Lymphoma Society; Rising Tide Foundation

Completed

TLR9 Agonist SD-101, Ibrutinib, and Radiation Therapy in Treating Patients With Relapsed or Refractory Grade 1-3A Follicular Lymphoma

Mantle Cell Lymphoma | Marginal Zone Lymphoma | Recurrent Follicular Lymphoma | Refractory Follicular Lymphoma | Grade 1 Follicular Lymphoma | Grade 2 Follicular Lymphoma | Grade 3a Follicular Lymphoma

United States
Ain Shams University

Completed

Omega-3 Fatty Acids Supplementation Improves Early-stage Diabetic Nephropathy and Subclinical Atherosclerosis in Pediatric Patients With Type 1 Diabetes

Diabetes Mellitus, Type 1

Egypt
University of Alabama at Birmingham

Completed

Cabozantinib for Plexiform Neurofibromas (PN) in Subjects With NF1 in Children and Adults (NF105-CABO)

Neurofibromatosis | Plexiform Neurofibromas | NF1

United States
Queensland Centre for Gynaecological Cancer
The University of Queensland; Queensland University of Technology

Active, not recruiting

Improving the Treatment for Women With Early Stage Cancer of the Uterus (feMMe)

Complex Endometrial Hyperplasia With Atypia | Grade 1 Endometrial Endometrioid Adenocarcinoma

Australia, New Zealand
Ixaka Ltd
Andalusian Network for Design and Translation of Advanced Therapies

Terminated

The Efficacy and Safety of REX-001 to Treat Ischemic Ulcers in Subjects With CLI Rutherford Category 5 and DM

Cardiovascular Disease | Diabetes Mellitus, Type 2 | Diabetes Mellitus, Type 1 | Critical Limb Ischemia (CLI) | Peripheral Arterial Disease (PAD) | Diabetes Mellitus (DM)

Spain, Netherlands, United Kingdom, Czechia, Portugal, Hungary
Levenson, David I., M.D.

Completed

mRNA Based-Covid-19 Vaccine Effects on Blood Glucose Levels

Hyperglycemia | Diabetes Mellitus, Type 2 | Diabetes Mellitus, Type 1 | Vaccine Adverse Reaction

United States
National Cancer Institute (NCI)
NRG Oncology

Completed

Medroxyprogesterone Acetate With or Without Entinostat Before Surgery in Treating Patients With Endometrioid Endometrial Cancer

FIGO Grade 1 Endometrial Endometrioid Adenocarcinoma | FIGO Grade 2 Endometrial Endometrioid Adenocarcinoma | FIGO Grade 3 Endometrial Endometrioid Adenocarcinoma

United States
University Hospital, Montpellier

Terminated

Evaluation of the Severity of Cardiovascular Autonomic Neuropathy in Type 1 Diabetic Patients With OSAS (DIADYSAS)

Sleep Apnea, Obstructive | Diabetes Mellitus, Type 1

France
Kirby Institute
Gilead Sciences; Melanoma Institute Australia; St Vincent's Hospital, Sydney; Royal... and other collaborators

Active, not recruiting

Coronavirus (COVID-19) Outcomes Registries in Immunocompromised Individuals Australia (CORIA) (CORIA)

COVID-19 | Cancer | Primary Immune Deficiency Disorder | HIV-1-infection | Immunosuppression Disorders

Australia
Ixaka Ltd
Andalusian Network for Design and Translation of Advanced Therapies

Terminated

The Efficacy and Safety of REX-001 to Treat Ischemic Rest Pain in Subjects With CLI Rutherford Category 4 and DM

Cardiovascular Disease | Diabetes Mellitus, Type 2 | Diabetes Mellitus, Type 1 | Critical Limb Ischemia (CLI) | Peripheral Arterial Disease (PAD) | Diabetes Mellitus (DM)

Spain, Czechia, Portugal, Hungary, Germany, Poland
National Cancer Institute (NCI)

Completed

Study of Plexiform Neurofibromas in Neurofibromatosis Type 1

Plexiform Neurofibromas | NF1

United States
National Cancer Institute (NCI)

Completed

Acceptance and Commitment Therapy for Adolescents and Young Adults With Neurofibromatosis and Chronic Pain

Neurofibromatosis

United States
National Cancer Institute (NCI)

Completed

Tivantinib With or Without Erlotinib Hydrochloride in Treating Patients With Metastatic or Locally Advanced Kidney Cancer That Cannot Be Removed by Surgery

Recurrent Renal Cell Carcinoma | Stage III Renal Cell Cancer | Stage IV Renal Cell Cancer | Type 1 Papillary Renal Cell Carcinoma | Type 2 Papillary Renal Cell Carcinoma

United States
Medical University of Vienna

Unknown

Pulsed Oral Sirolimus in Autosomal Dominant Polycystic Kidney Disease (RAP)

Polycystic Kidney, Type 1 Autosomal Dominant Disease | Polycystic Kidney, Type 2 Autosomal Dominant Disease

Austria
Hospital Universitário Professor Edgard Santos

Completed

Urological Physical Therapy in HTLV-1 With Urinary Symptoms (UROHTLV)

Tropical Spastic Paraparesis | HTLV-1

Brazil
National Cancer Institute (NCI)

Completed

Bevacizumab With or Without TRC105 in Treating Patients With Metastatic Kidney Cancer

Clear Cell Renal Cell Carcinoma | Recurrent Renal Cell Carcinoma | Stage IV Renal Cell Cancer | Type 1 Papillary Renal Cell Carcinoma | Type 2 Papillary Renal Cell Carcinoma

United States, Taiwan, Australia
Indiana University
Pfizer; United States Department of Defense

Terminated

Study of Sutent®/Sunitinib (SU11248) in Subjects With NF-1 Plexiform Neurofibromas

Neurofibromatosis | Plexiform Neurofibromas | NF1

United States
Holdsworth House Medical Practice

Completed

The Prevalence of Neurocognitive Disorder in a Primary Care-based HIV Cohort Compared to a HIV-negative Control Cohort - (CNS HAND)

HIV-1-Associated Cognitive Motor Complex
University of Genova

Unknown

Treadmill, Stretching and Proprioceptive Exercise (TreSPE) Rehabilitation Program for Charcot-Marie-Tooth Neuropathy Type 1A (CMT1A) (TreSPE)

Charcot-Marie-Tooth Disease | Charcot-Marie-Tooth Disease Type 1A

Italy
Shanghai Ninth People's Hospital Affiliated to...

Recruiting

A Retrospective Study on Epidemiological Characteristics of Chinese NF1 Patients in Real World (PROMISE)

Neurofibromatosis 1 | Plexiform Neurofibroma

China
University of Alabama at Birmingham
Children's Hospital of Philadelphia; Congressionally Directed Medical Research...

Not yet recruiting

Selumetinib for the Prevention of Plexiform Neurofibroma Growth in NF Type 1 (NF114)

Neurofibromatosis 1 | Plexiform Neurofibroma
National Cancer Institute (NCI)

Recruiting

Decitabine/Cedazuridine (INQOVI), an Oral DNA Demethylating Agent, in Subjects With BAP1 Cancer Predisposition Syndrome and Subclinical, Early-Stage Mesothelioma

Mesothelioma | BRCA1-Associated Protein-1 (BAP1) Mutations | Malignant Mesothelioma (MM) | Early-stage Mesothelioma | Subclinical Mesothelioma | Early-stage BAP1-associated Malignancies

United States

Clinical Trials on DYT 1

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