Clinical Trials on Dementia, Multi-Infarct in Netherlands

Total 324 results

Leiden University Medical Center
Erasmus Medical Center; Academisch Medisch Centrum - Universiteit van Amsterdam... and other collaborators

Active, not recruiting

Aeration, Breathing, Clamping Study 3 (ABC3)

Preterm Infant | Birth, Preterm

Netherlands
Vivoryon Therapeutics N.V.
Amsterdam UMC, location VUmc; Julius Clinical

Completed

Safety and Tolerability of PQ912 in Subjects With Early Alzheimer's Disease (SAPHIR)

Alzheimer's Disease

Spain, Finland, Germany, Netherlands, Belgium, France, Sweden
Academisch Medisch Centrum - Universiteit van Amsterdam...

Recruiting

Performance and Patient Acceptance of a Commercially Available Beverage as Compared to an Oral Glucose Solution for Oral Glucose Tolerance Tests in Cystic Fibrosis (CF) Patients Who Are Screened for CF-related Diabetes.

Cystic Fibrosis | Cystic Fibrosis-related Diabetes

Netherlands
Novartis Pharmaceuticals

Completed

A Study Evaluating the Safety and Efficacy of Topical BPR277 for the Treatment of Atopic Dermatitis and Netherton Syndrome (3)

Healthy Volunteers | Atopic Dermatitis | Netherton Syndrome

Netherlands, United States
EIP Pharma Inc
National Institute on Aging (NIA); Worldwide Clinical Trials; CervoMed, Inc

Active, not recruiting

RewinD-LB - Clinical Study of Neflamapimod in Patients With Dementia With Lewy Bodies

Dementia With Lewy Bodies

United States, United Kingdom, Netherlands
Denali Therapeutics Inc.
Takeda

Active, not recruiting

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of DNL593 in Healthy Participants and Participants With Frontotemporal Dementia (FTD-GRN)

Frontotemporal Dementia

Spain, Turkey, France, Belgium, Netherlands, Portugal, Italy, Colombia, Czechia, Brazil, United Kingdom, Serbia
Erasmus Medical Center
Stichting TAAI

Active, not recruiting

TAAI Erasmus Research Initiative to Fight CF: Monitoring Inflammation in CF Lung Disease Into a New Era (TERRIFIC-MILE)

Lung Diseases | Cystic Fibrosis | Infections, Bacterial | Congenital Disorders | Lung Inflammation | Lung Infection | Lung Disease; Cystic | Lung Disease; Cystic, Congenital | Inflammation Lungs | Exacerbation, Symptom

Netherlands
Ruth Kaufmann, MD

Completed

Mesh Versus Suture Repair for Umbilical Hernias (HUMP)

Umbilical Hernia

Netherlands, Germany, Italy
prof. dr. Frans B. Plötz
Dutch Society of Pediatrics; Zorgevaluatie Nederland; Care4Neo; everywhereIM

Recruiting

Safely Reduce Newborn Antibiotic Exposure With the Early-onset Sepsis Calculator

EOS | Early-Onset Sepsis, Neonatal

Netherlands
Wave Life Sciences Ltd.

Terminated

Study of WVE-004 in Patients With C9orf72-associated Amyotrophic Lateral Sclerosis (ALS) or Frontotemporal Dementia (FTD) (FOCUS-C9)

ALS | FTD

Canada, Belgium, New Zealand, Netherlands, Australia, Sweden, United Kingdom, Ireland
TauRx Therapeutics Ltd

Completed

Safety and Efficacy Study Evaluating TRx0237 in Subjects With Behavioral Variant Frontotemporal Dementia (bvFTD)

Behavioral Variant Frontotemporal Dementia (bvFTD)

United States, Australia, Canada, Croatia, Poland, Netherlands, United Kingdom, Spain, Germany, Italy, Romania, Singapore
Karolinska Institutet
Harvard Medical School (HMS and HSDM); Karolinska University Hospital; National... and other collaborators

Recruiting

The Neonatal Hemorrhagic Risk Assessment in Thrombocytopenia (NEOHAT-2)

Bleeding | Neonatal Thrombocytopenia

United States, Netherlands, Sweden
Academisch Medisch Centrum - Universiteit van Amsterdam...
University of Sao Paulo; National University of Ireland, Galway, Ireland; Carlos...

Active, not recruiting

PRactice of VENTilation in Patients With ARDS Due to COVID-19 vs Pneumonia (PRoVENT-COP)

COVID-19 | Pneumonia | Acute Respiratory Distress Syndrome | Mechanical Ventilation Complication

Netherlands, Argentina, Brazil, Ireland, Spain
Janssen Research & Development, LLC

Terminated

An Efficacy and Safety Study of Atabecestat in Participants Who Are Asymptomatic at Risk for Developing Alzheimer's Dementia (EARLY)

Asymptomatic Amyloid-positive

United States, Canada, United Kingdom, Belgium, Germany, Spain, Japan, Australia, Netherlands, Denmark, Mexico, Finland, Sweden
Central Clinical Hospital of the Russian Academy...
Ural State Medical University; De Haar Research Task Force; De Haar Research... and other collaborators

Terminated

Natural History of Coronary Atherosclerosis in Real-World Stable Chest Pain Patients Underwent Computed Tomography Angiography in Comparison With Invasive Multimodality Imaging (REALITY)

Coronary Artery Disease | Alzheimer Disease | Contrast-induced Nephropathy | Coronary Atherosclerosis | Cerebrovascular Disease | Stable Chronic Angina | Chronic Coronary Insufficiency

Netherlands, Russian Federation, Estonia
Vivoryon Therapeutics N.V.
Amsterdam UMC, location VUmc; Nordic Bioscience A/S

Completed

A Study to Evaluate Safety and Tolerability of Different Doses and Efficacy of PQ912 in Subjects With MCI and Mild AD (VIVIAD)

Early Alzheimers Disease | Mild Cognitive Impairment Due to AD

Netherlands, Spain, Denmark, Germany, Poland
Axovant Sciences Ltd.

Terminated

Long-Term Extension Study of Intepirdine (RVT-101) in Subjects With Dementia With Lewy Bodies: HEADWAY-DLB Extension

Dementia With Lewy Bodies

United States, Canada, France, Italy, Netherlands, Spain, United Kingdom
Axovant Sciences Ltd.

Completed

Study Evaluating Intepirdine (RVT-101) in Subjects With Dementia With Lewy Bodies: The HEADWAY-DLB Study

Dementia With Lewy Bodies

United States, Canada, France, Italy, Netherlands, Spain, United Kingdom
Vertex Pharmaceuticals Incorporated

Completed

Study of VX-121 in Healthy Subjects and in Subjects With Cystic Fibrosis

Cystic Fibrosis

Netherlands, United Kingdom
Institut National de la Santé Et de la Recherche...
Assistance Publique - Hôpitaux de Paris; Cardiff University; Karolinska Institutet and other collaborators

Withdrawn

TINN2: Treat Infection in NeoNates 2 (TINN2)

Bronchopulmonary Dysplasia

Belgium, France, Germany, Hungary, Italy, Luxembourg, Netherlands, Sweden, United Kingdom
Novartis Pharmaceuticals

Completed

Safety, Tolerability and Abeta-specific Antibody Response of Repeated i.m. Injections of Adjuvanted CAD106 in Mild Alzheimer Patients

Alzheimer's Disease

Belgium, Switzerland, Spain, United States, Italy, Sweden, Canada, Germany, Norway, Netherlands
Maastricht University Medical Center

Recruiting

Qualitative Study in Patients With Genodermatoses and Healthcare Professionals on Reproductive Counselling

Quality of Life | Tuberous Sclerosis | Basal Cell Nevus Syndrome | Cutis Laxa | Epidermolysis Bullosa | Ichthyosis | Ectodermal Dysplasia | Albinism | Birt-Hogg-Dube Syndrome | Palmoplantar Keratoses

Netherlands
EIP Pharma Inc
Amsterdam UMC, location VUmc; Worldwide Clinical Trials

Completed

Proof-of-Concept Study of a Selective p38 MAPK Alpha Inhibitor, Neflamapimod, in Subjects With Mild Alzheimer's Disease (REVERSE-SD)

Alzheimer Disease

United States, Netherlands, United Kingdom, Czechia, Denmark
Maastricht University Medical Center

Enrolling by invitation

Reproductive Options in Inherited Skin Diseases (REPRO-ISD)

Tuberous Sclerosis | Basal Cell Nevus Syndrome | Cutis Laxa | Epidermolysis Bullosa | Ichthyosis | Ectodermal Dysplasia | Albinism | Xeroderma Pigmentosum | Birt-Hogg-Dube Syndrome | Palmoplantar Keratoses

Netherlands
Academisch Medisch Centrum - Universiteit van Amsterdam...

Recruiting

Personalized Mechanical Ventilation Guided by UltraSound in Patients With Acute Respiratory Distress Syndrome

ARDS, Human | Mechanical Ventilation | Lung Ultrasound

Denmark, Italy, Netherlands, Belgium, Greece, Ireland, Poland
TauRx Therapeutics Ltd

Terminated

Open-Label Study of Leuco-methylthioninium Bis(Hydromethanesulfonate) (LMTM) in Subjects With Alzheimer's Disease or Behavioral Variant Frontotemporal Dementia (bvFTD)

Alzheimer's Disease | Behavioral Variant Frontotemporal Dementia

Korea, Republic of, United States, Spain, Taiwan, Canada, Belgium, Malaysia, United Kingdom, Australia, Singapore, Croatia, Finland, France, Germany, Netherlands, Romania, Russian Federation
FUJIFILM Toyama Chemical Co., Ltd.

Completed

Efficacy and Safety of T-817MA in Patients With Mild Cognitive Impairment Due to Alzheimer's Disease (AD) or Mild AD

Mild Cognitive Impairment

Netherlands, United Kingdom, Ireland, Spain, Germany, Czechia, Hungary
Novartis

Completed

Long-term Safety of Rivastigmine Capsule and Patch in Patients With Mild to Moderately-severe Dementia Associated With Parkinson's Disease (PDD)

Parkinson's Disease Dementia

United States, Belgium, Italy, United Kingdom, Germany, Australia, Austria, Spain, Canada, France, Netherlands, Turkey, Argentina
Franciscus Gasthuis
Erasmus Medical Center

Completed

Reduction of Intravenous Antibiotics In Neonates (RAIN)

Neonatal Infection | Neonatal SEPSIS

Netherlands
Biogen

Recruiting

A Study to Learn About the Safety of BIIB080 and Whether it Can Improve Symptoms of Participants With Mild Cognitive Impairment Due to Alzheimer's Disease (AD) or Mild AD Dementia Between 50 to 80 Years of Age (CELIA)

Mild Cognitive Impairment Due to Alzheimer's Disease | Alzheimer's Disease Dementia

Belgium, Australia, Italy, United States, Spain, Denmark, United Kingdom, Czechia, France, Poland, Canada, Switzerland, Germany, Japan, Finland, Netherlands, Sweden
Shire

Completed

Long-term Safety and Efficacy Outcome Study Comparing Children Previously Enrolled in Study ROPP-2008-01 for the Prevention of Retinopathy of Prematurity (ROP) (PEDAL)

Retinopathy of Prematurity (ROP)

United States, Italy, Netherlands, Poland, Sweden, United Kingdom
University Medical Center Groningen
Radboud University Medical Center; Universitaire Ziekenhuizen KU Leuven; Amsterdam...

Completed

Social Cognition in Children Treated for a Brain Tumour

Brain Neoplasms | Cystic Fibrosis | Social Behaviour

Belgium, Netherlands
Bellus Health Inc

Unknown

European Study of 3APS in Mild to Moderate Alzheimer's Disease Patients

Alzheimer's Disease

Poland, France, Spain, Switzerland, Netherlands, Italy, Germany, Sweden, United Kingdom, Belgium
Cognition Therapeutics
National Institute on Aging (NIA)

Completed

A Study to Evaluate the Safety and Efficacy of CT1812 in Subjects With Mild to Moderate Alzheimer's Disease.

Mild to Moderate Alzheimer's Disease

United States, Australia, Netherlands, Czechia, Spain
IntraBio Inc

Active, not recruiting

A Pivotal Study of N-Acetyl-L-Leucine on Niemann-Pick Disease Type C

Niemann-Pick Disease, Type C

United States, Australia, United Kingdom, Germany, Slovakia, Netherlands, Czechia, Switzerland
Alector Inc.

Active, not recruiting

A Phase 3 Study to Evaluate Efficacy and Safety of AL001 in Frontotemporal Dementia (INFRONT-3)

Frontotemporal Dementia

Spain, United States, Portugal, United Kingdom, France, Germany, Netherlands, Belgium, Australia, Italy, Turkey, Switzerland, Argentina, Canada, Greece, Sweden
Anavex Life Sciences Corp.
Anavex Australia Pty Ltd.; Anavex Germany GmbH

Active, not recruiting

OLE of Phase 2b/3 Study ANAVEX2-73-AD-004 (ATTENTION-AD)

Alzheimer Disease

Australia, Canada, Germany, Netherlands, United Kingdom
Boehringer Ingelheim

Completed

Alzheimer Disease Proof of Concept Study With BI 409306 Versus Placebo

Alzheimer Disease

United States, Spain, Canada, United Kingdom, Germany, Italy, Netherlands, Portugal, Austria, Belgium, France, Poland
Anavex Life Sciences Corp.
Anavex Australia Pty Ltd.; Anavex Germany GmbH; Anavex Canada Ltd.

Completed

ANAVEX2-73 for Treatment of Early Alzheimer's Disease

Alzheimer Disease

Australia, Canada, Germany, Netherlands, United Kingdom
Leiden University Medical Center
ZonMw: The Netherlands Organisation for Health Research and Development; Horizon...

Recruiting

Phase I/II Clinical Trial Stem Cell Gene Therapy in RAG1-Deficient SCID (RAG1-SCID)

Severe Combined Immunodeficiency Due to RAG1 Deficiency

Spain, Netherlands, Italy, Poland, Australia, Turkey, United Kingdom
AstraZeneca

Withdrawn

Study to Assess Efficacy of AZD1236 in Patients With Cystic Fibrosis (CYBER)

Cystic Fibrosis

Netherlands, Poland, Spain, Canada
Regeneron Pharmaceuticals

Recruiting

A Trial to Study if REGN5837 in Combination With Odronextamab is Safe for Participants With Aggressive B-cell Non-Hodgkin Lymphomas (ATHENA-1)

B-cell Non-Hodgkins Lymphoma (B-NHL)

United States, Spain, United Kingdom, Netherlands
LEO Pharma

Terminated

Efficacy and Safety of 3 Doses of HL10 Given at Fixed Time Intervals Compared to Standard Therapy

Acute Respiratory Distress Syndrome | Acute Lung Injury

Denmark, Belgium, Austria, Canada, Finland, France, Germany, Netherlands, Norway, Spain, Sweden, United Kingdom
Hoffmann-La Roche

Terminated

A Study to Evaluate the Safety and Tolerability of Long-term Administration of Gantenerumab in Participants With Alzheimer's Disease (AD)

Alzheimer Disease

United States, Korea, Republic of, Canada, Poland, Argentina, Australia, Italy, Japan, Netherlands, Spain, Switzerland, Turkey, Chile, Mexico, United Kingdom, Denmark, Russian Federation
PRInnovation GmbH
Julius Clinical; Federal Agency for Disruptive Innovation - SPRIN-D; Priavoid

Recruiting

Study to Assess Safety and Efficacy of PRI-002 in Patients With MCI to Mild Dementia Due to Alzheimer's Disease (AD) (PRImus-AD)

Mild Cognitive Impairment Due to Alzheimer's Disease | Alzheimer's Disease, Early Onset

Spain, Germany, Italy, Czechia, Netherlands, Poland
Pfizer

Terminated

A Long-Term Safety And Tolerability Study Of Bapineuzumab In Alzheimer Disease Patients

Alzheimer Disease

Australia, France, Finland, Portugal, Spain, United Kingdom, Poland, Japan, Italy, Belgium, Switzerland, Netherlands, Chile, Slovakia, Sweden, New Zealand, South Africa
St George's, University of London
Assistance Publique - Hôpitaux de Paris; MRC/UVRI and LSHTM Uganda Research... and other collaborators

Recruiting

Serocorrelate of Protection Against GBS (PREPARE WP3)

Group B Streptococcus Carrier in Childbirth | Group B Streptococcal Infection, Late-Onset | Group B Streptococcal Infection, Early-Onset | Group B Streptococcus Neonatal Sepsis | Group B Strep Infection

France, Italy, Malawi, Netherlands, Uganda, United Kingdom
Eli Lilly and Company

Terminated

Study of LY2886721 in Mild Cognitive Impairment Due to Alzheimer's Disease or Mild Alzheimer's Disease

Alzheimer's Disease

United States, Italy, Japan, Spain, Netherlands
Alector Inc.
AbbVie

Active, not recruiting

A Phase 2 Study to Evaluate Efficacy and Safety of AL002 in Participants With Early Alzheimer's Disease (INVOKE-2)

Alzheimer Disease

United States, Spain, France, Germany, Australia, Canada, Poland, Italy, Argentina, Netherlands, United Kingdom, New Zealand
UCB Biopharma SRL

Active, not recruiting

A Study to Test the Efficacy, Safety, and Tolerability of Bepranemab (UCB0107) in Patients With Mild Cognitive Impairment or Mild Alzheimer's Disease (AD)

Alzheimer's Disease

United States, Belgium, Canada, France, Germany, Italy, Netherlands, Poland, Spain, United Kingdom

Clinical Trials on Dementia, Multi-Infarct in Netherlands

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