Clinical Trials on Digestive Tract Cancer in China

Total 16742 results

Henan Provincial People's Hospital
CSPC Ouyi Pharmaceutical Co., Ltd.

Recruiting

Efficacy and Safety Study of Nab-Paclitaxel Combined With Cisplatin in Second or Later-Line Treatment in Advanced Biliary Tract Cancers

Advanced Biliary Tract Cancers

China
Tianjin Medical University Cancer Institute and...

Recruiting

Cadonilimab Plus Regorafenib and Gem-Cis Chemotherapy in Advanced Biliary Tract Cancer

Advanced Biliary Tract Cancer

China
The First Affiliated Hospital of Zhengzhou University

Recruiting

Anlotinib Plus TQB2450 Combined With Nab-paclitaxel and Cisplatin as First-line Treatment for Advanced Biliary Tract Cancer

Advanced Biliary Tract Cancer

China
Tianjin Medical University Cancer Institute and...
CSPC Ouyi Pharmaceutical Co., Ltd.

Recruiting

Efficacy and Safety of Irinotecan Liposome Injection Combined With 5-FU/LV± Immunotherapy in First-line Gemsitabine + Immunoprogressive Patients With Metastatic Biliary Tract Cancer

Metastatic Biliary Tract Cancer

China
Fudan University

Recruiting

Cryoablation Combined With Sintilimab Plus Lenvatinib in Patients With Immune Checkpoint Inhibitor Previously Treated Advanced Biliary Tract Cancer （CASTLE-08） (CASTLE-08)

Advanced Biliary Tract Cancer

China
Peking University

Completed

HAIC With Oxaliplatin, 5-FU and Bevacizumab Plus Intravenous Toripalimab for Advanced BTC

Advanced Biliary Tract Cancer

China
Chinese PLA General Hospital

Unknown

A Phase I/II Study of the Pan-immunotherapy in Patients With Local Advanced/Metastatic BTC

Biliary Tract Cancer (BTC)

China
Sun Yat-sen University
Jiangsu Hengrui Pharmaceutical Co., Ltd.

Not yet recruiting

A Phase Ib/II Clinical Study of Camrelizumab and Apatinib Plus GP in the Treatment of Advanced Biliary Tract Cancer

Metastatic Biliary Tract Cancer | Locally Advanced Biliary Tract Cancer

China
Fudan University

Recruiting

Oncolytic Virotherapy Combined With Tislelizumab Plus Lenvatinib in Patients With Advanced Biliary Tract Cancer (OPTIONS-05) (OPTIONS-05)

Advanced Biliary Tract Cancer

China
Tianjin Medical University Cancer Institute and...

Recruiting

Durvalumab Combined With Chemotherapy Neoadjuvant Therapy of Biliary Tract Cancer

Resectable Biliary Tract Cancer

China
Peking Union Medical College Hospital
Shanghai Junshi Bioscience Co., Ltd.

Recruiting

Toripalimab Plus Lenvatinib as Second-line Treatment in Advanced Biliary Tract Cancers

Advanced Biliary Tract Cancer

China
Dai, Guanghai

Unknown

Toripalimab Combined With S1 and Albumin Paclitaxel in Patients With Advanced Biliary Tract Cancer

Advanced Biliary Tract Cancer

China
Sun Yat-sen University

Recruiting

Envofolimab and Lenvatinib Combined With Gemcitabine Plus Cisplatin for Advanced BTC as First-Line Treatment(ENLIGHTEN)

Advanced Biliary Tract Cancer

China
Innovent Biologics (Suzhou) Co. Ltd.

Recruiting

IBI310 in Combination With Sintilimab in Patients With Advanced Biliary Tract Cancer

Advanced Biliary Tract Cancer

China
Peking Union Medical College Hospital
Geneplus-Beijing Co. Ltd.

Active, not recruiting

Exploratory Study on the Therapeutic Effect Prediction Model of Advanced BTC Immunotherapy

Biliary Tract Cancer | Predictive Cancer Model | Immune Checkpoint Inhibitor

China
AstraZeneca

Active, not recruiting

A Phase 3b, Open-label, Multi-center Study on Durvalumab in Combination With Gemcitabine-based Chemotherapy as 1L Treatment for the Chinese Patients With Unresectable Biliary Tract Cancers (BTC) (TopDouble)

Biliary Tract Cancers

China
Peking University Cancer Hospital & Institute

Recruiting

KN046 Plus Regorafenib or Apatinib in MSI-H Digestive System Cancers Resistant to PD-1/PD-L1 Blockade

Digestive System Cancers

China
Yi Miao
Nanjing Abingen Biotech Co. Ltd

Unknown

T Cell Mediated Adaptive Therapy for Her2-positive Neoplasms of Digestive System

Gastric Cancer | Pancreatic Cancer | Esophageal Cancer | Bowel Cancer | Liver Cancer | Gallbladder Cancer

China
The Affiliated Hospital of Xuzhou Medical University
Guangzhou Bioresette Biomedical Technology Co., Ltd.

Recruiting

BGT007H Cells for the Treatment of Refractory Digestive System Tumors

Digestive Tract Cancer

China
Zhejiang Cancer Hospital

Recruiting

A Single-Arm Phase II Exploratory Clinical Study of Pemigatinib in the Treatment of Advanced Gastrointestinal Cancer (Excluding Biliary Tract Cancer) Patients With FGFR Alterations Who Have Failed Standard Therapy

Gastrointestinal Cancer

China
Fudan University

Recruiting

Capecitabine Combined With Lenvatinib and Tislelizumab as Adjuvant Treatment After Resection in Patients With BTC

Biliary Tract Cancer

China
Shanghai Zhongshan Hospital
Shanghai Junshi Bioscience Co., Ltd.; OrigiMed

Completed

A Study of the Efficacy and Safety of Chemotherapy Combined With Toripalimab in Advanced Biliary Tract Cancer

Biliary Tract Cancer

China
Shanghai Zhongshan Hospital
Transcenta Holding Limited

Completed

TST001 in Patients With CLDN18.2 Positive Previously Treated Advanced Biliary Tract Cancer

Biliary Tract Neoplasms

China
Lee's Pharmaceutical Limited

Enrolling by invitation

A Clinical Study of PD-L1 Antibody ZKAB001 Combined With Capecitabine in Resected Biliary Tract Cancer

Biliary Tract Cancer

China
Jiangsu HengRui Medicine Co., Ltd.

Not yet recruiting

Phase II Clinical Study of SHR-A1811 in Patients With HER2 Expression / Amplification of Locally Advanced Unresectable or Recurrent Metastatic Biliary Tract Cancer

HER2 Expression / Amplification in Patients With Biliary Tract Cancer

China
National Cancer Institute (NCI)

Completed

A Population-Based Case-Control Study of Biliary Tract Cancers in Shanghai, China

Biliary Tract Cancer

China
Hutchison Medipharma Limited

Unknown

A Trial Evaluating Surufatinib Efficacy and Safety in Biliary Tract Carcinoma Patients

Biliary Tract Cancer

China
Chinese PLA General Hospital

Unknown

Study of PD-1 Inhibitor in Combination With Gemcitabine/Cisplatin for Advancer BTCs

Biliary Tract Cancer

China
Peking University

Completed

Study of Hepatic Arterial Infusion to Treat Biliary Tract Carcinomas

Biliary Tract Cancer

China
Shanghai East Hospital

Not yet recruiting

Circulating Tumor DNA Guided Adjuvant Chemotherapy for Biliary Tract Carcinoma

Biliary Tract Cancer

China
ASLAN Pharmaceuticals

Completed

Varlitinib Plus Capecitabine in Chinese Patients With Advanced or Metastatic Biliary Tract Cancer

Biliary Tract Cancer

China
RenJi Hospital
Shanghai Changzheng Hospital; Yangpu District Central Hospital Affiliated to... and other collaborators

Unknown

The Role of ctDNA and PBMC in Treatment of Biliary Tract Cancer

Biliary Tract Neoplasms

China
Fudan University

Recruiting

GEMOX Combined With Donafenib and Tislelizumab in Biliary Tract Cancer

Biliary Tract Carcinoma

China
Peking University Cancer Hospital & Institute

Not yet recruiting

KN026 Plus Chemotherapy ± KN-046 in HER2 Positive Colorectal Cancer and Biliary Carcinoma

HER2-positive Colorectal Cancer | HER2-positive Biliary Tract Cancer

China
Peking Union Medical College Hospital

Recruiting

Durvalumab and Lenvatinib With or Without Chemotherapy in First-Line Treatment of Advanced Biliary Tract Cancer

Biliary Tract Neoplasms | Immunotherapy

China
Huazhong University of Science and Technology
CSPC Ouyi Pharmaceutical Co., Ltd.

Unknown

A Phase II Study for Nab-paclitaxel Plus Cisplatin vs Gemcitabine Plus Cispatin as First Line Chemotherapy in Advanced Biliary Tract Cancer

Biliary Tract Cancer

China
The First Hospital of Jilin University

Recruiting

Lenvatinib Combined With PD-1 Inhibitors as First-line Treatment for Unresectable/Advanced Biliary Tract Carcinoma (LEADER-001)

Biliary Tract Cancer

China
Zhejiang University

Completed

Second-line Irinotecan and Capecitabine Versus Irinotecan for Gemcitabine and Cisplatin Refractory Biliary Tract Cancer

Biliary Tract Neoplasms

China
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Recruiting

A Single-arm Phase II Clinical Study of the Efficacy and Safety of Camrelizumab Combined With GEMOX for Unresectable GBCs

Unresectable Gallbladder Cancer

China
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

Not yet recruiting

A Clinical Study of a Preoperative Translational Therapy for Unresectable Gallbladder Cancer

Unresectable Gallbladder Cancer

China
Zhejiang Cancer Hospital

Recruiting

A Randomized, Multicenter Phase II Basket Study of Hypofractionated Radiotherapy/Stereotactic Body Radiotherapy Followed by Immunotherapy-Based Systemic Therapy +/- L. Rhamnosus M9 for the First-Line Treatment of Advanced Digestive System Malignancies.

Gastric Cancer | Colorectal Cancer | Pancreatic Adenocarcinoma | Biliary Tract Cancer | Gastroesophageal Junction Adenocarcinoma | Liver Cancer Stage IV

China
Zhejiang Cancer Hospital

Unknown

Anlotinib in Combination With PD1 With Gemcitabine Plus(+)Cisplatin for Unresectable or Metastatic Biliary Tract Cancer

Biliary Tract Cancer

China
Peking Union Medical College Hospital

Recruiting

Toripalimab With or Without Lenvatinib or Chemotherapy in First-Line Treatment of Advanced Biliary Tract Cancer

Biliary Tract Neoplasms Immunotherapy

China
Peking Union Medical College Hospital

Recruiting

Pembrolizumab With or Without Lenvatinib or Chemotherapy in First-Line Treatment of Advanced Biliary Tract Cancer

Biliary Tract Neoplasms Immunotherapy

China
Second Affiliated Hospital, School of Medicine,...
Guangzhou Burning Rock Dx Co., Ltd.

Recruiting

Early-stage Detection of LIver, Biliary tRAct and pancReatic Cancers

Pancreatic Cancer | Liver Cancer | Biliary Tract Cancer

China
Fudan University

Active, not recruiting

Combination of Gemcitabine, Oxaliplatin, Sintilimab and Bevacizumab in Unresectable Biliary Tract Cancer

Biliary Tract Carcinoma | Initially Unresectable

China
Shanghai Zhongshan Hospital

Recruiting

Candonilimab in Combination With LM-302 for Claudin 18.2 Positive-advanced Biliary Tract Cancer After Failure of Standard of Chemotherapy and PD1/PD-L1 Antibody

Biliary Tract Cancer | Candonilimab | Claudin 18.2

China
Eastern Hepatobiliary Surgery Hospital
Guangzhou Burning Rock Bioengineering Co., Ltd

Recruiting

AssesSment of Early-deteCtion basEd oN liquiD Biopsy in Biliary Tract Cancer (ASCEND-BTC)

Biliary Tract Cancer

China
Sun Yat-sen University

Unknown

A Pilot Study of Genomic Sequencing Guided Individualized Therapy in Gastrointestinal Cancers, GITIC Study (GITIC)

Gastrointestinal Cancers

China
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Suzhou Suncadia Biopharmaceuticals Co., Ltd.

Recruiting

Adebrelimab and a TKI in Combination With GEMOX in First-line Treatment of Advanced Biliary Tract Cancers (BTC)

Biliary Tract Cancer | Gemox Chemotherapy

China

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